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Trends on medicine use in county public hospitals in Sanming,China from 2011 to 2017 被引量:1
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作者 Aichen Yu Mengyuan Fu +8 位作者 Bingyu Ni Chunxia Man Jingyuan Zhang Huajie Hu Ye Tian Yue Zhou Sheng Han Xiaodong Guan Luwen Shi 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2022年第3期218-223,共6页
Sanming model in healthcare reform has attracted much attention due to its comprehensive and efficient exploration,while its impact on physicians’prescribing behavior remains unknown.In the present study,we aimed to ... Sanming model in healthcare reform has attracted much attention due to its comprehensive and efficient exploration,while its impact on physicians’prescribing behavior remains unknown.In the present study,we aimed to evaluate the impact of Sanming reform on physicians’medicine use in county-level public hospitals.We collected outpatient prescriptions in the internal medicine and pediatric departments from nine county public hospitals in Sanming from January 2011 to December 2017.We used six prescribing indicators to analyze physicians’medicine use.The Mann-Kendall test was used to examine trends in the study outcomes.A total of 1577904 outpatient prescriptions were included in this study.The average prescription rate of antibiotics and combined antibiotics were 57.5%and 12.2%in 2011,respectively,which were declined to 28.2%(P=0.007)and 2.9%(P=0.003)in 2017,respectively.The average prescription rate of injection was 30.2%in 2011 and declined to 5.3%(P=0.003)in 2017.As for the subgroup analysis of the internal medicine and pediatric departments,the average prescription rate of antibiotics was 39.3%and 71.4%in 2011,respectively,which was declined to 10.2%(P=0.003)and 47.3%(P=0.035)in 2017,respectively.The average prescription rate of combined antibiotics was 15.9%and 9.4%in 2011,respectively,which was declined to 2.9%(P=0.003)and 2.9%(P=0.016),respectively.The average prescription rate of injection was 17.8%and 39.6%in 2011,respectively,which was declined to 1.9%(P=0.003)and 9.0%(P=0.003),respectively.Our study showed a significant decreasing trend in antibiotic use in county-level public hospitals after the Sanming healthcare reform,indicating that the reform successfully promoted the appropriate use of medicine to some extent. 展开更多
关键词 Sanming healthcare reform medicine use Prescribing behavior
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Use of Chinese Herbal Medicine Therapies in Comprehensive Hospitals in Central China: A Parallel Survey in Cancer Patients and Clinicians 被引量:3
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作者 陈刚 乔婷婷 +5 位作者 丁浩 李晨曦 郑慧玲 陈晓玲 胡少明 于世英 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2015年第6期808-814,共7页
Summary: Chinese herbal medicine (CHM), as the largest application category of traditional Chinese medicine (TCM), is widely accepted among cancer patients in China. Herbal slice (HS) and Chinese patent drug (... Summary: Chinese herbal medicine (CHM), as the largest application category of traditional Chinese medicine (TCM), is widely accepted among cancer patients in China. Herbal slice (HS) and Chinese patent drug (CPD) are commonly used CHM in China. This study aimed to investigate the utilization of CHM among clinicians and cancer patients in central China. Five hundred and twenty-five patients and 165 clinicians in 35 comprehensive hospitals in central China were asked to complete an anonymous questionnaire that was designed to evaluate the use of CHM. The results showed that 90.74% clinicians and 72.24% cancer patients used CHM during cancer treatment. The educational backgrounds of the clinicians and the age, education level, annual income, and cancer stage of the cancer patients were re- lated to use of CHM. More than 90% clinicians and cancer patients had used CPD. Comparatively, the percentage of HS use was 10% lower than that of CPD use among clinicians and cancer patients. More clinicians preferred to use CHM after surgery than cancer patients did (20.41% vs. 5.37%). Enhancing physical fitness and improving performance status were regarded as the most potential effect of CHM on cancer treatment (85.71% among clinicians and 94.07% among cancer patients), in comparison with directly killing tumor cells (24.49% among clinicians and 31.36% among patients). As for refusal rea- sons, imprecise efficacy was the unanimous (100%) reason for clinicians' rejection of CHM, and 95.58% patients objected to using CHM also for this reason. Furthermore, the side effects of CHM were more concerned by clinicians than by patients (33.33% vs. 15.81%). In conclusion, our survey revealed that CHM was popularly accepted by clinicians and cancer patients in central China. The reasons of use and rejection of CHM were different between clinicians and cancer patients. 展开更多
关键词 A Parallel Survey in Cancer Patients and Clinicians use of Chinese Herbal medicine Therapies in Comprehensive Hospitals in Central China
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Evaluation of Clinical Efficacy of Combined Use of Acupuncture and Medicine in Treating Sleep Disorder in Patients with Anxiety Disorder 被引量:1
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作者 Xiangpu LIU Jingping MU +3 位作者 Xinhua YU Shun ZENG Nannan LIU Xiaohu ZHU 《Medicinal Plant》 CAS 2021年第3期91-93,共3页
[Objectives]To evaluate the clinical efficacy of combined acupuncture and medicine in the treatment of sleep disorders in patients with anxiety disorders.[Methods]A total of 300 anxiety patients with sleep disorders w... [Objectives]To evaluate the clinical efficacy of combined acupuncture and medicine in the treatment of sleep disorders in patients with anxiety disorders.[Methods]A total of 300 anxiety patients with sleep disorders were randomly selected and divided into a research group and a control group,with 150 cases in each group.The control group was administered with western medicine,and the research group was treated with acupuncture and medicine to compare their clinical treatment effects.[Results]The total effective rate of treatment in the research group was significantly higher than that in the control group;after treatment,both the PSQI and SAS scores of the two groups were significantly reduced,and the reduction degree of the research group was higher than that of the control group,the difference was statistically significant(P<0.05).[Conclusions]Combined use of acupuncture and medicine to treat sleep disorders in patients with anxiety disorders has better curative effect and fewer adverse reactions,so it has high clinical application value. 展开更多
关键词 Combined use of acupuncture and medicine Anxiety disorder Sleep disorder
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Published papers about Salvia miltiorrhiza Bunge used in traditional Chinese medicine
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《Journal of Pharmaceutical Analysis》 SCIE CAS 2011年第4期309-318,共10页
Chu Kedan, Ji Guolu, Shi Hong, Xie Weirong, Zhang Yuqin, Zhang Xiaoqin. Study of the alcohol extraction process of Shenhu granules. Strait Pharmaceutical Journal, 2011, 23(03): 21-24. Email: chukd5917@ 163.com
关键词 EMAIL Published papers about Salvia miltiorrhiza Bunge used in traditional Chinese medicine ZHANG
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The method of external use of Chinese medicine in prevention of epidemic disease and its application in COVID-19
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作者 Jia-Shuai Deng Kai Li +1 位作者 Gui-Juan Pan Yong Jiang 《Journal of Hainan Medical University》 2020年第17期1-5,共5页
The ancient people of our country have accumulated rich experience in prevention of epidemic disease in the course of fighting the epidemic for thousands of years,and invented effective methods of external use of Chin... The ancient people of our country have accumulated rich experience in prevention of epidemic disease in the course of fighting the epidemic for thousands of years,and invented effective methods of external use of Chinese medicine for preventing epidemic,some of these methods have been still used today,in addition to ensuring the health and safety of ancient people in China.In the COVID-19 ravaged China today,all kinds of protective supplies for the general public is difficult to get,so the study of external use of Chinese medicine that preventing epidemic for modern society is still very significant and valuable.According to the characteristics of COVID-19 and the theory of combination of disease-syndrome,based on the applicability and feasibility for modern society,combed out three methods of external use of Chinese medicine,including medicine hanging,medicine smearing and medicine fumigation,and made corresponding application recommendations for hospitals,communities,families to prevent epidemic disease. 展开更多
关键词 PESTILENCE COVID-19 External use of Chinese medicine medicine hanging medicine smearing medicine fumigation Common Pathogenesis Individual Pathogenesis
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Cases analysis of rational use of medicine (31) Nongonococcal urethritis(NGU)
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《天津药学》 2008年第5期77-78,共2页
1.Patient's conditionsA 29-year-old man,was infected with nongonococcal urethritis(NGU).He complained that he had dysuria and discomfort in the urethra and mucopurulent discharge,which appeared one week after inte... 1.Patient's conditionsA 29-year-old man,was infected with nongonococcal urethritis(NGU).He complained that he had dysuria and discomfort in the urethra and mucopurulent discharge,which appeared one week after intercourse. 展开更多
关键词 NGU Nongonococcal urethritis Cases analysis of rational use of medicine
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Analysis of plant resources and diversity in the southeast area of Taihang Mountains
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作者 Junpeng Lin Jingming Jia Anhua Wang 《Asian Journal of Traditional Medicines》 2024年第2期88-98,共11页
Taihang Mountains are situated between Shanxi Province and the North China Plain,spanning Beijing,Hebei,Shanxi,and Henan provinces and cities.The mountains extend from northeast to southwest for over 400 km,naturally ... Taihang Mountains are situated between Shanxi Province and the North China Plain,spanning Beijing,Hebei,Shanxi,and Henan provinces and cities.The mountains extend from northeast to southwest for over 400 km,naturally deviding the second step from the third one in China.The southeastern area of Taihang Mountains specifically refers to Changzhi City and Jincheng Administrative Region of Shanxi Province.Given Shanxi Province’s robust development plans for the southeast area of Taihang Mountains,the medicinal plant resources in this area will be affected.Therefore,it is imperative and urgent to conduct a comprehensive investigation and study on the medicinal plant resources in the southeast area of Taihang Mountains.By means of field investigation,literature review,and specimen identification,the plant resources and diversity of two counties in the southeast of Taihang Mountains were evaluated.The findings revealed 234 plants species across 172 genera in 70 families,primarily comprising angiosperms.The families with more species included Compositae,Leguminosae,Rosaceae,Labiatae,Ranunculaceae.Among the genera,those with more species were Cynanchum,Selaginella,Clematis,Thalictrum,and Rhamnus.A total of 114 medicinal plants were identified,constituting 48.72%of the total.Regarding medicinal parts,the concentration is in roots and rhizomes,followed by whole plants and fruits.On the basis of investigation and study,some suggestions on the development,utilization,and protection of medicinal plant resources in southeast Taihang Mountains were made.These suggestions provide valuable insights for the study on medicinal plant resources and vegetation in the southeast of Taihang Mountains,serving as a scientific basis for the protection and sustainable utilization of wild medicinal plant resources. 展开更多
关键词 plant resources DIVERSITY medicinal use protection and utilization Taihang Mountains
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Analysis of plant resources and diversity in Balluk Mountain, Xinjiang Uygur Autonomous Region
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作者 Minli Ruan Anhua Wang Jingming Jia 《Asian Journal of Traditional Medicines》 2024年第1期10-25,共16页
Balluk Mountain is located between the Tianshan Mountains and the Altai Mountains in Xinjiang Province.Influenced by the humid air and diverse landforms of Lake Alacuri,the unique climate of Mount Baluk nourishes exce... Balluk Mountain is located between the Tianshan Mountains and the Altai Mountains in Xinjiang Province.Influenced by the humid air and diverse landforms of Lake Alacuri,the unique climate of Mount Baluk nourishes excellent pastures and supports numerous wildlife,making it rich in plant resources.The 9th Shenyang Pharmaceutical University Chinese Medicine Resources Scientific Expedition Team conducted field investigations,literature reviews,and specimen identification to study the plant resources and diversity of Balluk Mountain in Xinjiang Province.A total of 235 species of medicinal plants belonging to 59 families and 159 genera were collected during the period from July to August 2015 in this area.The dominant families observed were Asteraceae,Caryophyllaceae,Lamiaceae,Ranunculaceae,Rosaceae and Umbelliferae,with 35,11,14,12,27,and 13 species respectively.These families account for over 47.4%of the total species collected,though comprising only 10.2%of the total number of families.At the genus level,Artemisia was found to be the most dominant genus with eight species,contributing to 0.63%of the total genera,while representing 3.4%of the total species abundance.Overall,this study provides an updated analysis of the plant resources and diversity in Balluk Mountain.Several species have been identified to possess significant medicinal properties and hold potential for various research fields,including natural product chemistry and drug development.The study also offers practical and meaningful suggestions for strengthening the protection and utilization of plant resources in the area.By implementing these suggestions,we can better preserve the plant diversity in Balluk Mountain and ensure the sustainable use of these valuable resources. 展开更多
关键词 plant resources DIVERSITY medicinal use protection and utilization Balluk Mountain
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Analysis of vascular plant resources and diversity in Fanjing Mountain,Guizhou Province
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作者 Hu Chen Guoqing Long +1 位作者 Anhua Wang Jingming Jia 《Asian Journal of Traditional Medicines》 2024年第3期137-151,共15页
Fanjing Mountain Nature Reserve is located at the junction of Jiangkou,Yinjiang and Songtao counties in the Tongren region of Guizhou Province.Because of the topography and humid climate of the central subtropical mon... Fanjing Mountain Nature Reserve is located at the junction of Jiangkou,Yinjiang and Songtao counties in the Tongren region of Guizhou Province.Because of the topography and humid climate of the central subtropical monsoonal mountains,the plant species in this area are rich and diverse.The vascular plant resources and diversity of Fanjing Mountain Nature Reserve in Guizhou Province were studied through field survey,literature review and specimen identification.The results show that there are 284 species of vascular plants in the region,belonging to 205 genera in 93 families,mainly angiosperms.Liliaceae,Asteraceae,Polygonaceae,Leguminosae,Ranunculaceae and Polygonum have the most species,followed by Sedum,Dioscorea,Actinidia Lindl and Thalictrum.In terms of life types,perennial herbs are the most dominant,accounting for 68.47%of the total number of species,and annual(or biennial)herbs,shrubs and vine types also present.There are 222 species identified as medicinal vascular plants,accounting for 78.2%of the total number of species.The medicinal parts are primarily found in the whole herb category,followed by the root and rhizome category. 展开更多
关键词 plant resources DIVERSITY medicinal use conservation and utilization Fanjing Mountain Nature Reserve
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Analysis of wild medicinal vascular plant resources and diversity in Dabie Mountains, Anhui Province
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作者 Qing Wang Minli Ruan +1 位作者 Anhua Wang Jingming Jia 《Asian Journal of Traditional Medicines》 2024年第4期192-210,共19页
Dabie Mountains are located at the junction of Anhui,Henan and Hubei provinces in the East of China.With its varied altitude,climate,and soil texture,Dabie Mountains are extremely rich in wild plant resources.The 12th... Dabie Mountains are located at the junction of Anhui,Henan and Hubei provinces in the East of China.With its varied altitude,climate,and soil texture,Dabie Mountains are extremely rich in wild plant resources.The 12th Traditional Chinese Medicine(TCM)Resources Scientific Expedition Team of Shenyang Pharmaceutical University conducted a study on wild vascular plants resources,especially medicinal vascular plants,through field investigation,literature review and specimen identification.There were 472 species of vascular plants belonging to 347 genera and 125 families collected during July 2018 in this area,of which 424 species were medicinal vascular plants,accounting for 89.83%of the total.From the perspective of medicinal parts,most of the medicinal plants there have values in their roots and rhizomes,as well as the whole plants.The efficacy and characteristics of these pharmaceutical dimensions were also summarized and analyzed in detail.Besides,among the wild vascular plants collected,the most dominant families with the biggest numbers of species are Compositae,Lamiaceae,Liliaceae,Rosaceae,Leguminosae,Ranunculaceae,Saxifragaceae and Polygonaceae,and the dominant genus are Viola and Sedum.In terms of life form,perennial herbs are dominant,accounting for 55.72%of the total species,followed by some annual(or biennial)herbs,shrubs and lianas.Finally,recommendations are put forward for strengthening the protection and utilization of wild medicinal plant resources in Dabie Mountains. 展开更多
关键词 Dabie Mountains medicinal vascular plant resources plant diversity medicinal use protection and utilization
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Analysis of plant resources and diversity in Shennongjia Area of Hubei Province,China
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作者 Terigen Bao Min Li +1 位作者 Jingming Jia Anhua Wang 《Asian Journal of Traditional Medicines》 2024年第2期66-87,共22页
Shennongjia Area is located in northwest of Hubei Province with Shennongding,the highest peak(3105.4 m above sea level)in central China.The unique geographical location and complex terrain of this region make it rich ... Shennongjia Area is located in northwest of Hubei Province with Shennongding,the highest peak(3105.4 m above sea level)in central China.The unique geographical location and complex terrain of this region make it rich in plant resources.After field investigation,th literature review,and specimen identification,the 7 Shenyang Pharmaceutical University Chinese Medicine Resources Scientific Expedition Team studied the plant resources and diversity of Shennongjia Area.454 species of vascular plants belonging to 106 families and 275 genera were collected from July to August in 2013.The dominant families are Lamiaceae,Ranunculaceae,Rosaceae,and Asteraceae,with 20,21,37 and 48 species respectively.At the genus level,Rubus is the dominant one with 11 species.3 species of national first-class protective plants,13 species of“Huan yang yao”and 36 species of“Qi yao”were collected.In all,our research has updated the plant recources and diversity in Shennongjia Area.Furthermore,by putting forward practical and meaningful suggestions on strengthening the protection and utilization of plant resources in Shennongjia Area,our research will help to protect the diverse ecosystem there. 展开更多
关键词 plant resources DIVERSITY medicinal use Shennongjia Area
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Safe Disposal of Medicines in Palestine
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作者 Qusai N. Al-Shahed Anhar Assali Ruba Najjar 《Journal of Pharmacy and Pharmacology》 2016年第1期17-22,共6页
The disposal of unwanted and expired medications has been a concern to public health practitioners, and patients alike. The objective of the current investigation was to look closely at the practice of patients and ca... The disposal of unwanted and expired medications has been a concern to public health practitioners, and patients alike. The objective of the current investigation was to look closely at the practice of patients and carers in Nablus-Palestine with regard to disposal of unused or expired medicines. The study was a cross-sectional survey administered via face-to-face structured interviews with randomly selected patients, community pharmacists and physicians from Nablus-Palestine. Two hundred and fifty patients/carers completed a questionnaire regarding medicines disposal current practice, effects on environment, and their views to overcome this problem. Most of the people completing the questionnaire (67%) stated that they throw unwanted medicines in the normal household bins, and about 75% think that this can impose illegal and environmental hazards. Nearly half of the questionnaire showed that main reason for need to dispose medicines was possessing expired ones with almost believe there should be more appropriate way to dispose medicines. About 95% said they have not been directed for safe disposal of medicines with 46% thinking that a national campaign can be very educative in this issue mainly through Ministry of Health (54%) followed by .73% of the sampled patients were in favor of national campaign to direct people to safe disposal of medicines. This pilot study in Nablus clearly highlights the need for appropriate method for safe disposal of medicines in Palestine through guidelines in pharmacies and hospitals. A well organized method for collecting unwanted medicines from people should be encouraged through appropriate teaching of patients and caters about effects of waste medicines on environment as well as being domestic hazard. The data and information is valuable for furthering discussions regarding patients behaviour and also provides a basis for future research into determining what quantities of active pharmaceutical ingredients (APIs) are disposed, enter the environment and what effects it can impose. 展开更多
关键词 Active pharmaceutical ingredients medicines disposal medicine use.
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Traditional Chinese medicine of Salvia miltiorrhiza Bunge: a review of phytochemistry, pharmacology and pharmacokinetics 被引量:3
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作者 Ebuka-Olisaemeka Nwafor Peng Lu +7 位作者 Jia-Wei Li Qing-Qing Zhang Dong-Li Qi Zhi-Dong Liu Hui Peng Huan Qin Yan-Quan Gao Ji-Lin Wang 《Traditional Medicine Research》 2021年第4期62-86,共25页
Salvia miltiorrhiza Bunge,known as red sage or Danshen,is commonly applied in Chinese herbal therapeutics for various biological effects.In 25-220 C.E.,the earliest Chinese Materia Medica referred to as Shengong’s Cl... Salvia miltiorrhiza Bunge,known as red sage or Danshen,is commonly applied in Chinese herbal therapeutics for various biological effects.In 25-220 C.E.,the earliest Chinese Materia Medica referred to as Shengong’s Classic of Materia Medica(Eastern Han Dynasty of China,200 C.E.)initially documented Salvia miltiorrhiza Bunge.Currently,Salvia miltiorrhiza Bunge is one of the most frequently prescribed traditional Chinese medicines in clinics for antidiabetic,antianxiety,antihypertensive,antidepressant,antilipidemic,antiarrhythmic,and anticancer effects.Undoubtedly,it is best known for improving and promoting blood circulation;thus,its recommendation for use in cardiovascular disorders.Regarding this article,important information was sourced both manually and electronically using patent compendium and databases,including Google Scholar,herbal plant monographs,Hindawi,PubMed,Embase,CNKI,pharmacopoeias,Springer,etc.Well-concise details and discussions on the botany,traditional medicinal uses,chemical constituents-phytochemistry,pharmacokinetics,pharmacology,and toxicology information are presented.In perspective,understanding the comprehensive information of the above-stated fields with regards to Salvia miltiorrhiza Bunge would yield an additional positive knowledge on areas that need urgent attention and identify gaps in research and safety for future consideration. 展开更多
关键词 Traditional medicinal uses Salvia miltiorrhiza Bunge PHYTOCHEMISTRY TOXICOLOGY Quality control PHARMACOLOGY
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In vitro screening of traditionally used medicinal plants in China against Enteroviruses 被引量:13
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作者 Jin-Peng Guo Ji Pang Xin-Wei Wang Zhi-Qiang Shen Min Jin Jun-Wen Li 《World Journal of Gastroenterology》 SCIE CAS CSCD 2006年第25期4078-4081,共4页
AIM: To search for new antiviral agents from traditional Chinese medicine, specifically anti-enterovirosuses agents. METHODS: The aqueous extracts (AE) of more than 100 traditionally used medicinal plants in China... AIM: To search for new antiviral agents from traditional Chinese medicine, specifically anti-enterovirosuses agents. METHODS: The aqueous extracts (AE) of more than 100 traditionally used medicinal plants in China were evaluated for their in vitro anti-Coxsackie virus B3 activities with a MTT-based colorimetric assay. RESULTS: The test for AE of 16 plants exhibited anti- Coxsackie virus B3 activities at different magnitudes of potency. They can inhibit three steps (inactivation, adsorption and replication) during the infection. Among the 16 plants, Sargentodoxa cuneata (Oliv.) Rehd. et Wils., Sophora tonkinensis Gapnep., Paeonia veitchii Lynch, Spatholobus suberectus Dunn. and Cyrtorniurn fortunei J, sm. also have activity against other enterovirus, including Coxsackie virus 135, Polio virus I, Echo virus 9 and Echo virus 29. Cell cytotoxic assay demonstrated that all tested AE had CC50 values higher than their EC50 values. CONCLUSION: The sixteen traditionally used medicinal plants in China possessed antMral activity, and some of them merit further investigations. 展开更多
关键词 Traditional used medicinal plant China Antiviral activity Enterovirus Sargentodoxa cuneata(O/iv) Reid. et. W/Is. Sophora tonkinensis Gapnep. Paeonia veitchii Lynch. Cyrtomium fortunei J. sm. Spatholobus suberectus Dunn
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Euphorbia tirucalli L.:Review on morphology,medicinal uses,phytochemistry and pharmacological activities
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作者 Prashant Y. Mali Shital S. Panchal 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2017年第7期603-613,共11页
The intention of current review is to make available up-to-date information on morphology, ecological biodiversity, medicinal uses, phytochemistry and pharmacolog-ical activities on different parts of Euphorbia tiruca... The intention of current review is to make available up-to-date information on morphology, ecological biodiversity, medicinal uses, phytochemistry and pharmacolog-ical activities on different parts of Euphorbia tirucalli (E. tirucalli). This plant has a number of medicinal uses. Latex of E. tirucalli is vesicant and rubefacient which is used for rheumatism, warts, cough, asthma, ear-ache, tooth-ache and neuralgia. It acts as a purgative in small doses while in big doses it is bitter irritant and emetic. Milky juice is alexiteric, carminative and purgative. It is useful in whooping cough, gonorrhea, asthma, leprosy, dropsy, dyspepsia, enlargement of spleen, colic, jaundice and stone in bladder. The fresh milky juice is good alternative in syphilis and a good application in neuralgia. A decoction of branches is used in gastralgia and colic. Bark is used in treatment of fractures. Poultices prepared from the stem are useful to repair the broken bones. Boiled root liquid acts as an emetic in cases of snake-bite and for infertility in women. The wood is used for rafters, toys and veneering purposes. It is also useful against leprosy and foot paralysis subsequent to childbirth. E. tirucalli is reported to have euphol, β-sitosterol, euphorbol hexacosonate, cycloeuphordenol, cyclotirucanenol, tirucalicine, tri-methyl ellagic acid, gallic acids, terpenic alcohol, isoeuphorol, taraxasterol, tirucallol, euphor-one, euphorcinol, euphorbins, 12-deoxy-4β-hydroxyphorbol-13-phenyl acetate-20-acetate, 12, 20-dideoxyphorbol-13-isobutyrate, glut-5-en-3-β-ol, 3,3′-di-O-methylellagic acid, euphorbin-A (polyphenol), tirucallin-A (7) (tannin), tirucallin-B (11), euphorbin-F (14) (dimers), cycloartenol, 24-methylenecycloartenol, ingenol triacetate, 12-deoxy-4β-hydroxyphorbol-13-phenyl acetate-20-acetate, taraxerone, euphorginol, taraxerol, cam-pesterol, stigmasterol, palmitic acid, linoleic acid,β-amyrin, etc. active phytoconstituents. E. tirucalli have possessed activity in human-lymphocytes, analgesic, anthelmintics, antiarthritic, antibacterial/antifungal/antimicrobial, anti-HIV, anti-inflammatory, antioxi-dant, antiviral, biodiesel production, CNS depressant/neuropathic pain, cytotoxicity/anticancer, genotoxic/mutagenic, hepatoprotective, insect repellants, immunomodulatory, larvicidal, molluscicidal/ovicidal/piscicidal, myelopoiesis, proteolytic/chitinolytics phar-macological activities. There is a need to isolate dynamic constituents, their biological trial, molecular mechanisms, experimental protection and legalization of therapeutic uses of E. tirucalli. The collected information will be helpful to locate up study protocol for recent drugs and Ayurvedic formulation expansion in curative and treat a variety of ailments. 展开更多
关键词 Euphorbia tirucalli MORPHOLOGY Ecological biodiversity Medicinal uses PHYTOCHEMISTRY ANTICANCER
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Analysis of vascular plant resources and diversity in Machin County,Qinghai Province
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作者 Hu Chen Dongdong Wang +2 位作者 Qing Wang Anhua Wang Jingming Jia 《Asian Journal of Traditional Medicines》 2023年第6期271-279,共9页
Machin County is situated in the Sanjiangyuan Nature Reserve in the southeastern part of Qinghai Province.Influenced by the special topography and climate of the Qinghai-Tibet Plateau,Machin County has complex and div... Machin County is situated in the Sanjiangyuan Nature Reserve in the southeastern part of Qinghai Province.Influenced by the special topography and climate of the Qinghai-Tibet Plateau,Machin County has complex and diverse plant species.The vascular plant resources and diversity in Machin County were studied through field survey,literature review and specimen identification.The results show that there are 47 families and 127 genera and 256 species of vascular plants in the region,basically angiosperms,including those containing more species of the family Asteraceae,Buttercup,Genus Ginseng,Leguminosae and Rosaceae,and those containing more species of the genus Artemisia,Artemisia,Aster and Donzonia.In terms of life type,perennial herbs are the most dominant ones,accounting for 77.34%of the total number of species,followed by some annual(or biennial)herbs and shrub types.There are 191 species of medicinal vascular plants,accounting for 74.61%of the total number of species,including 48 species of Tibetan medicine.In terms of the medicinal parts of these plants,whole herb category is the most common one,followed by the root and rhizome category.Based on the investigation and research,we have proposed the conservation and utilization of plant resources in Machin County,Qinghai Province. 展开更多
关键词 plant resources DIVERSITY medicinal use conservation and utilization Tibetan medicine Machin County
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Cultural Heritage Assets: Rituals, Grinding Hollows and Other Socio-Cultural Practices in Simiyu Region, Tanzania 被引量:2
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作者 Charles B. Saanane 《Natural Resources》 2016年第4期214-238,共25页
This paper presents results from preliminary assessments in Ngasamo ward, Busega district in Simiyu region. The main objective was to assess cultural heritage assets in some areas of Bariadi district in Simiyu region.... This paper presents results from preliminary assessments in Ngasamo ward, Busega district in Simiyu region. The main objective was to assess cultural heritage assets in some areas of Bariadi district in Simiyu region. Specific objectives of the assessment are to identify tangible cultural heritage resources in Simiyu region;to identify intangible cultural heritage resources in Simiyu region;and to provide suggestions for pertinent protection, conservation and presentation of cultural heritage resources. The assessment was carried out through surveys that included documentation together with records for Global Positioning System (GPS) coordinates per surveyed locality;key informant interviews;and Focus Group Discussion. Results from the assessment revealed several worship areas that include immovable physical objects associated to ritual performance places. For example, wells like Luhuhi in Ilula village, Nkindwa biye tree in Ilula village, Magahi well in Isenge village, Isangijo hill at Isenge village, Dutwa well in Isenge village, Nyabusalu well in Igalukilo village and similar others are worship places that were revealed by informants. The assessment uncovered granite rock boulders that are being chopped off flakes for traditional medicine use in the area. Some cultural heritage sites have been identified such that a lot more needs to be explored in order to establish existence of other physical cultural heritage sites in Busega district, Bariadi district. For example, the grinding hollows, bao and the like are unique heritage resources. Such resources including undiscovered immovable archaeological objects would need presentation of sustainable preservation as well as conservation plans in line with Antiquities Acts, Antiquities Rules and Monuments of 1980 together with Cultural Heritage Policy of 2008. 展开更多
关键词 Grinding Hollows Traditional Rituals Rock Boulders for Traditional medicine use
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Fruits as Prospective Reserves of bioactive Compounds:A Review 被引量:5
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作者 Marines Marli Gniech Karasawa Chakravarthi Mohan 《Natural Products and Bioprospecting》 CAS 2018年第5期335-346,共12页
Astaxanthin is a value-added ketocarotenoid with great potential in nutraceutical and pharmaceutical industries.Genetic engineering of heterologous hosts for astaxanthin production has attracted great attention.In thi... Astaxanthin is a value-added ketocarotenoid with great potential in nutraceutical and pharmaceutical industries.Genetic engineering of heterologous hosts for astaxanthin production has attracted great attention.In this study,we assessed some key factors,including codon usage of the expressed genes,types of promoters,bacterial strains,and culture media,for engineered Escherichia coli to produce astaxanthin.The effect of codon usage was shown to be related to the types of promoters.E.coli DH5a was superior to other strains for astaxanthin production.Different culture media greatly affected the contents and yields of astaxanthin in engineered E.coli.When the expression cassette containing GadE promoter and its driving genes,HpCHY and CrBKT,was inserted into the plasmid pACCAR16DcrtX and expressed in E.coli DH5a,the engineered strain was able to produce 4.30±0.28 mg/g dry cell weight(DCW)or 24.16±2.03 mg/L of astaxanthin,which was a sevenfold or 40-fold increase over the initial production of 0.62±0.03 mg/g DCW or 0.61±0.05 mg/L. 展开更多
关键词 ANTICANCER Antioxidant Bioactive compounds Flavones FRUITS Medicinal uses
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Annona muricata:Is the natural therapy to most disease conditions including cancer growing in our backyard?A systematic review of its research history and future prospects 被引量:1
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作者 Yahaya Gavamukulya Fred Wamunyokoli Hany A.El-Shemy 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2017年第9期835-848,共14页
Annona muricata(A.muricata)is a tropical plant species belonging to family Annonaceae and known for its many medicinal uses.This review focuses on the research history of its traditional uses,phytochemicals,pharmacolo... Annona muricata(A.muricata)is a tropical plant species belonging to family Annonaceae and known for its many medicinal uses.This review focuses on the research history of its traditional uses,phytochemicals,pharmacological activities,toxicological aspects of the extracts and isolated compounds,as well as the in vitro propagation studies with the objective of stimulating further studies on this plant for human consumption and treatment.A.muricata extracts have been identified in tropical regions to traditionally treat diverse conditions ranging from fever to diabetes and cancer.More than 200 chemical compounds have been identified and isolated from this plant,the most important being alkaloids,phenols and acetogenins.Using in vitro studies,its extracts and phytochemicals have been characterized as antioxidant,anti-microbial,anti-inflammatory,insecticidal,larvicidal,and cytotoxic to cancer cells.In vivo studies have revealed anxiolytic,antistress,anti-inflammatory,immunomodulatory,antimalarial,antidepressant,gastro protective,wound healing,hepato-protective,hypoglycemic,anticancer and anti-tumoral activities.In silico studies have also been reported.In addition,clinical studies support the hypoglycemic as well as some anticancer activities.Mechanisms of action of some pharmacological activities have been elucidated.However,some phytochemical compounds isolated from A.muricata have shown a neurotoxic effect in vitro and in vivo,and therefore,these crude extracts and isolated compounds need to be further investigated to define the magnitude of the effects,optimal dosage,and mechanisms of action,long-term safety,and potential side effects.Additionally,more clinical studies are necessary to support the therapeutic potential of this plant.Some studies were also found to have successfully regenerated the plant in vitro,but with limited success.The reported toxicity notwithstanding,A.muricata extracts seem to be some of the safest and promising therapeutic agents of the 21st century and beyond that need to be studied further for better medicinal formulations and diseases management. 展开更多
关键词 Annona muricata Traditional medicinal uses PHYTOCHEMICALS ACETOGENINS Bioactivity Cytotoxicity
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Ethnobotanical profiling of the medicinal flora of Kotli,Azad Jammu and Kashmir,Pakistan:Empirical reflections on multinomial logit specifications 被引量:1
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作者 Muhammad Shoaib Amjad Muhammad Arshad +2 位作者 Abdul Saboor Sue Page Sunbal Khalil Chaudhari 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2017年第5期478-488,共11页
Objective:To report the indigenous people's uses of plants from a multidimensional perspective in a remote area where strong ethnobotanical cultural practices prevail. Methods:An ethnobotanical survey was conducte... Objective:To report the indigenous people's uses of plants from a multidimensional perspective in a remote area where strong ethnobotanical cultural practices prevail. Methods:An ethnobotanical survey was conducted in the field during 2014-2016. Ethnobotanical data were gathered from 182 informants through oral interviews and semi-structured questionnaires. The distribution of plants was explored using both descriptive and graphical methods. Further,a Multinomial Logit Specification was applied to find out the probability of the occurrence of diverse utilization of plants in multipurpose domains. Results:The study identified 202 plant species distributed among 71 families and 156 genera. Ethnobotanical data indicate that there are more medicinal(36.96%) uses of plants as compared to all other use categories. The output from the Multinomial Logit Specifications(MLS) model reveals that perennial and non-woody plants are exploited more for medicinal and food uses than annual and woody plants. In the context of ethnomedicinal uses,aerial plant parts particularly leaves are more extensively used for the preparation of herbal recipes as compared to underground parts. Conclusions:The results of the study emphasize the need to create awareness among the local communities about the conservation status of plant species in order to maintain a sustainable resource of plant-derived materials into the future. The novel econometric approach employed in this study adds a new insightful methodology to the existing body of literature in the field of ethnobotany. We strongly recommend conservation measures,alongside phytochemical and pharmacological studies on the useful plant species identified in this study in order to ensure their sustainable and effective utilization. 展开更多
关键词 ETHNOBOTANY Medicinal uses Multinomial logit Kotli Azad Kashmir Pakistan
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