It is now well accepted that ionizing radiation (IR) induces DNA damage responses in cells that are not hit directly by IR[1]. The irradiated cells are capable of transmitting signals into the neighboring cells throug...It is now well accepted that ionizing radiation (IR) induces DNA damage responses in cells that are not hit directly by IR[1]. The irradiated cells are capable of transmitting signals into the neighboring cells through gap junction and/or culture medium, resulting in a series of biological responses in non-irradiated cells. These responses are termed as radiation induced bystander effects (RIBE), which have been identified both in vitro and in vivo[2].展开更多
文摘It is now well accepted that ionizing radiation (IR) induces DNA damage responses in cells that are not hit directly by IR[1]. The irradiated cells are capable of transmitting signals into the neighboring cells through gap junction and/or culture medium, resulting in a series of biological responses in non-irradiated cells. These responses are termed as radiation induced bystander effects (RIBE), which have been identified both in vitro and in vivo[2].
