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Ambiguous clear cell carcinoma in medullary sponge kidney:A case report
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作者 Yang Chen Tianyu Li Jiwen Cheng 《Asian Journal of Urology》 CSCD 2020年第4期369-372,共4页
Medullary sponge kidney(MSK)is a characteristic renal malformation,with a relatively low incidence.Radiologically,identification of MSK is sometimes ambiguous when compared to a renal mass.Here,we report a novel renal... Medullary sponge kidney(MSK)is a characteristic renal malformation,with a relatively low incidence.Radiologically,identification of MSK is sometimes ambiguous when compared to a renal mass.Here,we report a novel renal clear cell carcinoma in MSK,and discuss our approach to treatment.We recommended that a preoperative biopsy should be performed,followed by a comprehensive discussion regarding the appropriate perioperative preparations and careful surgical techniques that should be performed for this complex disease. 展开更多
关键词 medullary sponge kidney Renal clear cell carcinoma Preoperative biopsy
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Nephrectomy in a Patient with Medullary Sponge Kidney Associated with Severe Nephrocalcinosis and Nephrolithiasis: A Rare Condition
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作者 Landry Oriole Mbouché Achille Aurèle Mbassi +3 位作者 Junior Mekeme Mekeme Axel Stéphane Nwaha Makon Pierre Joseph Fouda Fru Fobuzshi Angwafo III 《Open Journal of Urology》 2021年第9期332-341,共10页
<strong>Background:</strong> Medullary sponge kidney (MSK) is a disturbance of renal development characterized by cystic dilation and diffuse precalyceal duct ectasia. The disease affects both genders in e... <strong>Background:</strong> Medullary sponge kidney (MSK) is a disturbance of renal development characterized by cystic dilation and diffuse precalyceal duct ectasia. The disease affects both genders in equal proportions and is generally diagnosed in adulthood, as a result of recurrent calcium nephrolithiasis and nephrocalcinosis. The most frequently encountered manifestations being renal colic, microscopic or macroscopic hematuria, and fever. The intravenous pyelogram is standard for diagnosis and metabolic workup is required to identify the underlying cause. The main goal of treatment is to prevent recurrence and disease progression. Though considered a benign condition, a nephrectomy may often be required in patients presenting late with irreversible complications and end-stage renal disease.<strong> Aim:</strong> To highlight and discuss the presentation and management of a rare case of nephrocalcinosis and nephrolithiasis secondary to the medullary sponge kidney. <strong>Case presentation:</strong> We report herein the case of a 56-year-old male with long-standing hematuria in whom a diagnosis of medullary sponge kidney disease was made and he underwent a left total nephrectomy. The postoperative course was uneventful. <strong>Conclusion:</strong> Nephrocalcinosis and nephrolithiasis are complications of MSK and can result in irreversible renal damage. A high index of suspicion is necessary for patients presenting with renal colic, recurrent urinary tract infections, or hematuria for prompt diagnosis and management. 展开更多
关键词 medullary sponge kidney NEPHROLITHIASIS NEPHROCALCINOSIS NEPHRECTOMY
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The genetic framework for development of nephrolithiasis 被引量:5
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作者 Vinaya Vasudevan Patrick Samson +1 位作者 Arthur D.Smith Zeph Okeke 《Asian Journal of Urology》 2017年第1期18-26,共9页
Over 1%-15% of the population worldwide is affected by nephrolithiasis,which remains the most common and costly disease that urologists manage today.Identification of atrisk individuals remains a theoretical and techn... Over 1%-15% of the population worldwide is affected by nephrolithiasis,which remains the most common and costly disease that urologists manage today.Identification of atrisk individuals remains a theoretical and technological challenge.The search for monogenic causes of stone disease has been largely unfruitful and a technological challenge;however,several candidate genes have been implicated in the development of nephrolithiasis.In this review,we will review current data on the genetic inheritance of stone disease,as well as investigate the evolving role of genetic analysis and counseling in the management of nephrolithiasis. 展开更多
关键词 GENETICS HYPERCALCIURIA NEPHROLITHIASIS UROLITHIASIS Calcium sensing receptor CYSTINURIA medullary sponge kidney Autosomal dominant polcystic kidney disease Uric acid nephrolithiasis HYPERCALCIURIA
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