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Delayed Visual Recovery from Optic Nerve Injury Following a Procedure of Orbital Wall Reconstruction
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作者 Chengzhe Wu Yingjun Li +1 位作者 Xun Cui Zhengri Li 《Journal of Biosciences and Medicines》 2020年第1期38-41,共4页
The acute onset of the vision loss by optic never injury following orbital wall reconstruction, has been reported in 0.5% - 5.0% of the cases. Visual impairment can be recovered within an early period after injury. De... The acute onset of the vision loss by optic never injury following orbital wall reconstruction, has been reported in 0.5% - 5.0% of the cases. Visual impairment can be recovered within an early period after injury. Delayed visual recovery from optic nerve injury during a procedure of orbital wall reconstruction has not been reported. We report a case of delayed recovery from optic nerve injury which occurred following orbital wall reconstruction. A 78-year-old man underwent orbital wall reconstruction for medial wall fracture and resulting enophthalmos in the right eye, one week after a traffic accident. Immediate after surgery, postoperative visual acuity in the right eye decreased to light perception, and relative afferent pupillary defect (RAPD) was detected. In spite of mega-dose steroid treatment, the visual acuity did not improve. However, 8 months after surgery, visual acuity began to recover to 0.1, and the degree of RAPD decreased. Twelve months after surgery, visual acuity in the right eye was 0.4, and pupillary light reflex was normal. Our report suggests that patients with optic neuropathy by surgery or trauma require long-term follow-up, regardless of early response to mega-dose steroid treatment. 展开更多
关键词 VISUAL Loss DELAYED VISUAL Recovery Optic NERVE Injury mega-dose STEROID
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兆伏级锥形束CT成像剂量及其致继发肿瘤终生归因风险研究
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作者 闫少杰 闫先瑞 +3 位作者 陈张铭 王云刚 朱健 康玺 《中华肿瘤防治杂志》 CAS 北大核心 2023年第19期1161-1167,共7页
目的 评估胸部影像引导放射治疗中,兆伏级锥形束CT(MV-CBCT)成像在不同年龄患者各重要器官沉积的剂量,并预测成像剂量致继发肿瘤的终生归因风险(LAR)。方法 回顾性评估2018-02-01-2021-10-31山东省肿瘤防治研究院收治的206例年龄为3~70... 目的 评估胸部影像引导放射治疗中,兆伏级锥形束CT(MV-CBCT)成像在不同年龄患者各重要器官沉积的剂量,并预测成像剂量致继发肿瘤的终生归因风险(LAR)。方法 回顾性评估2018-02-01-2021-10-31山东省肿瘤防治研究院收治的206例年龄为3~70岁患者胸部MV-CBCT计划系统模拟的心脏、双侧肺、双侧乳腺等器官平均剂量和脊髓最大点剂量。建立成像野内器官剂量与胸围尺寸的线性关系。使用美国电离辐射生物效应委员会(BEIR)Ⅶ模型,预测MV-CBCT致不同年龄患者继发肿瘤的风险值。结果 206例患者以10 cm(头脚方向)×28 cm(左右方向)的开野范围模拟MV-CBCT扫描,其心脏、双侧肺、双侧乳腺和脊髓单次扫描的中位剂量分别为4.3(3.6~5.3)、2.7(1.9~5.0)、4.5(3.6~5.8)和3.7(2.8~4.9) cGy。射野内各器官平均剂量随着胸围的增大而单调减小。不同肿瘤LAR均随暴露年龄增大而降低。暴露年龄段为3~<10、10~<20、30~<40、50~<60和60~<70岁的男性肺癌LAR分别为2 539/10万人、1 729/10万人、750/10万人、649/10万人和594/10万人;女性分别为6 108/10万人、3 948/10万人、1 744/10万人、1 497/10万人和1 296/10万人。结论 在影像引导放射治疗过程中,MV-CBCT致成像野内器官的累积剂量可达约100 cGy,如叠加治疗场内低剂量区域,MV-CBCT增加继发肿瘤LAR则不可忽视。特别是暴露辐射年龄较小的儿童患者,制定放疗计划时应将该成像剂量潜在风险考虑在内。 展开更多
关键词 肿瘤 放射治疗 兆伏级锥形束CT 影像引导放射治疗 低剂量辐射 终生归因风险 继发肿瘤
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