Increasing prolificacy is an important aim in the pig industry. Regions associated with litter size have been revealed, but detailed molecular mechanisms are unclear. The Meishan pig is one of the most prolific breeds...Increasing prolificacy is an important aim in the pig industry. Regions associated with litter size have been revealed, but detailed molecular mechanisms are unclear. The Meishan pig is one of the most prolific breeds, with higher prolificacy than the Yorkshire pig, which exhibits high feeding efficiency and lean meat yield. The ovary is the key organ determining reproductive traits during pregnancy by synthesizing and secreting reproductive hormones essential for conceptus maintenance. In this comparative multi-omics study of the ovary transcriptome, proteome, and metabolome on day 49 of pregnancy, we aimed to identify genomic, proteomic, and metabolomic differences between the ovaries of Meishan and Yorkshire pigs to reveal potential molecular mechanisms conferring high prolificacy. Meishan pigs demonstrated general downregulation of steroid biosynthesis and butanoate metabolism in the ovary during mid-pregnancy at both transcriptome and proteome levels but exhibited higher serum cholesterol, estradiol, and progesterone levels than Yorkshire pigs. We also identified several single-nucleotide polymorphisms in the genes of the steroid hormone pathway associated with litter number, average birth weight, and total litter weight. Lower biosynthesis rates but elevated serum levels of reproductive hormones during mid-and late pregnancy are essential for the greater prolificacy of Meishan pigs.展开更多
The unique geographical environment and humanistic spirit of Meishan region gave birth to the Witchcraft exorcism cultur in Meishan,which has been passed down for thousands of years.The unique totem worship phenomenon...The unique geographical environment and humanistic spirit of Meishan region gave birth to the Witchcraft exorcism cultur in Meishan,which has been passed down for thousands of years.The unique totem worship phenomenon of Meishan people adds a footnote to the interpretation of the culture.The witchcraft culture of Meishan is the“living fossil”of the study of Meishan culture,and the totem worship of Meishan is its external cultural representation,reflecting the folk customs,religious beliefs,ethnic information,and life forms of Meishan area.The totem worship phenomenon is closely related to the concept of“animism”of Meishan people.展开更多
The Meishan Section of Changxing County, Zhejiang Province, China and the base of its Bed 27c,in which Hindeodus parvus first occurs, are recommended as the GSSP of Permian-Triassic boundary (PTB).The present paper in...The Meishan Section of Changxing County, Zhejiang Province, China and the base of its Bed 27c,in which Hindeodus parvus first occurs, are recommended as the GSSP of Permian-Triassic boundary (PTB).The present paper introduces a description of the section. Biostratigraphic correlation with other famous sections shows the completeness of this section and justifies choice of H. Parvus as the index fossil. Chemostratigraphic investigation provides the δ￣13C excursion and the moderate but inconsistent Ir spike as auxiliary symbols for the PTB. This boundary is closely related to transgression,anoxia,volcanism,mass extinction and possible impact events which can be correlated with those in South China and other parts of the world .展开更多
基金supported by the National Natural Science Foundation of China (31972541 and 31830090)the Central Public-interest Scientific Institution Basal Research Fund, China (Y2021XK20)+1 种基金the Special Construction Project Fund for Shandong Province Taishan Scholars, Chinathe Agricultural Science and Technology Innovation Program, China (ASTIP-IAS05)。
文摘Increasing prolificacy is an important aim in the pig industry. Regions associated with litter size have been revealed, but detailed molecular mechanisms are unclear. The Meishan pig is one of the most prolific breeds, with higher prolificacy than the Yorkshire pig, which exhibits high feeding efficiency and lean meat yield. The ovary is the key organ determining reproductive traits during pregnancy by synthesizing and secreting reproductive hormones essential for conceptus maintenance. In this comparative multi-omics study of the ovary transcriptome, proteome, and metabolome on day 49 of pregnancy, we aimed to identify genomic, proteomic, and metabolomic differences between the ovaries of Meishan and Yorkshire pigs to reveal potential molecular mechanisms conferring high prolificacy. Meishan pigs demonstrated general downregulation of steroid biosynthesis and butanoate metabolism in the ovary during mid-pregnancy at both transcriptome and proteome levels but exhibited higher serum cholesterol, estradiol, and progesterone levels than Yorkshire pigs. We also identified several single-nucleotide polymorphisms in the genes of the steroid hormone pathway associated with litter number, average birth weight, and total litter weight. Lower biosynthesis rates but elevated serum levels of reproductive hormones during mid-and late pregnancy are essential for the greater prolificacy of Meishan pigs.
基金Hunan Social Science Fund Project in 2022:Meishan Religious Art Research(22YBX021)。
文摘The unique geographical environment and humanistic spirit of Meishan region gave birth to the Witchcraft exorcism cultur in Meishan,which has been passed down for thousands of years.The unique totem worship phenomenon of Meishan people adds a footnote to the interpretation of the culture.The witchcraft culture of Meishan is the“living fossil”of the study of Meishan culture,and the totem worship of Meishan is its external cultural representation,reflecting the folk customs,religious beliefs,ethnic information,and life forms of Meishan area.The totem worship phenomenon is closely related to the concept of“animism”of Meishan people.
文摘The Meishan Section of Changxing County, Zhejiang Province, China and the base of its Bed 27c,in which Hindeodus parvus first occurs, are recommended as the GSSP of Permian-Triassic boundary (PTB).The present paper introduces a description of the section. Biostratigraphic correlation with other famous sections shows the completeness of this section and justifies choice of H. Parvus as the index fossil. Chemostratigraphic investigation provides the δ￣13C excursion and the moderate but inconsistent Ir spike as auxiliary symbols for the PTB. This boundary is closely related to transgression,anoxia,volcanism,mass extinction and possible impact events which can be correlated with those in South China and other parts of the world .
