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Valorization of Camellia oleifera oil processing byproducts to value-added chemicals and biobased materials: A critical review 被引量:3
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作者 Xudong Liu Yiying Wu +11 位作者 Yang Gao Zhicheng Jiang Zicheng Zhao Wenquan Zeng Mingyu Xie Sisi Liu Rukuan Liu Yan Chao Suli Nie Aihua Zhang Changzhu Li Zhihong Xiao 《Green Energy & Environment》 SCIE EI CAS CSCD 2024年第1期28-53,共26页
The C.oleifera oil processing industry generates large amounts of solid wastes,including C.oleifera shell(COS)and C.oleifera cake(COC).Distinct from generally acknowledged lignocellulosic biomass(corn stover,bamboo,bi... The C.oleifera oil processing industry generates large amounts of solid wastes,including C.oleifera shell(COS)and C.oleifera cake(COC).Distinct from generally acknowledged lignocellulosic biomass(corn stover,bamboo,birch,etc.),Camellia wastes contain diverse bioactive substances in addition to the abundant lignocellulosic components,and thus,the biorefinery utilization of C.oleifera processing byproducts involves complicated processing technologies.This reviewfirst summarizes various technologies for extracting and converting the main components in C.oleifera oil processing byproducts into value-added chemicals and biobased materials,as well as their potential applications.Microwave,ultrasound,and Soxhlet extractions are compared for the extraction of functional bioactive components(tannin,flavonoid,saponin,etc.),while solvothermal conversion and pyrolysis are discussed for the conversion of lignocellulosic components into value-added chemicals.The application areas of these chemicals according to their properties are introduced in detail,including utilizing antioxidant and anti-in-flammatory properties of the bioactive substances for the specific application,as well as drop-in chemicals for the substitution of unrenewable fossil fuel-derived products.In addition to chemical production,biochar fabricated from COS and its applications in thefields of adsorption,supercapacitor,soil remediation and wood composites are comprehensively reviewed and discussed.Finally,based on the compositions and structural characteristics of C.oleifera byproducts,the development of full-component valorization strategies and the expansion of the appli-cationfields are proposed. 展开更多
关键词 Camellia oleifera shell Camellia oleifera cake value-added chemicals Bioactive components Biobased materials
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Upcycling plastic wastes into value-added products via electrocatalysis and photoelectrocatalysis 被引量:1
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作者 Sungsoon Kim Dongjae Kong +1 位作者 Xiaolin Zheng Jong Hyeok Park 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第4期522-541,共20页
Plastic,renowned for its versatility,durability,and cost-effectiveness,is indispensable in modern society.Nevertheless,the annual production of nearly 400 million tons of plastic,coupled with a recycling rate of only ... Plastic,renowned for its versatility,durability,and cost-effectiveness,is indispensable in modern society.Nevertheless,the annual production of nearly 400 million tons of plastic,coupled with a recycling rate of only 9%,has led to a monumental environmental crisis.Plastic recycling has emerged as a vital response to this crisis,offering sustainable solutions to mitigate its environmental impact.Among these recycling efforts,plastic upcycling has garnered attention,which elevates discarded plastics into higher-value products.Here,electrocatalytic and photoelectrocatalytic treatments stand at the forefront of advanced plastic upcycling.Electrocatalytic or photoelectrocatalytic treatments involve chemical reactions that facilitate electron transfer through the electrode/electrolyte interface,driven by electrical or solar energy,respectively.These methods enable precise control of chemical reactions,harnessing potential,current density,or light to yield valuable chemical products.This review explores recent progress in plastic upcycling through electrocatalytic and photoelectrocatalytic pathways,offering promising solutions to the plastic waste crisis and advancing sustainability in the plastics industry. 展开更多
关键词 Plastic upcycling Electrocatalytic reaction Photoelectrocatalytic reaction value-added product
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Crosstalk among canonical Wnt and Hippo pathway members in skeletal muscle and at the neuromuscular junction
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作者 Said Hashemolhosseini Lea Gessler 《Neural Regeneration Research》 SCIE CAS 2025年第9期2464-2479,共16页
Skeletal muscles are essential for locomotion,posture,and metabolic regulation.To understand physiological processes,exercise adaptation,and muscle-related disorders,it is critical to understand the molecular pathways... Skeletal muscles are essential for locomotion,posture,and metabolic regulation.To understand physiological processes,exercise adaptation,and muscle-related disorders,it is critical to understand the molecular pathways that underlie skeletal muscle function.The process of muscle contra ction,orchestrated by a complex interplay of molecular events,is at the core of skeletal muscle function.Muscle contraction is initiated by an action potential and neuromuscular transmission requiring a neuromuscular junction.Within muscle fibers,calcium ions play a critical role in mediating the interaction between actin and myosin filaments that generate force.Regulation of calcium release from the sarcoplasmic reticulum plays a key role in excitation-contraction coupling.The development and growth of skeletal muscle are regulated by a network of molecular pathways collectively known as myogenesis.Myogenic regulators coordinate the diffe rentiation of myoblasts into mature muscle fibers.Signaling pathways regulate muscle protein synthesis and hypertrophy in response to mechanical stimuli and nutrient availability.Seve ral muscle-related diseases,including congenital myasthenic disorders,sarcopenia,muscular dystrophies,and metabolic myopathies,are underpinned by dys regulated molecular pathways in skeletal muscle.Therapeutic interventions aimed at preserving muscle mass and function,enhancing regeneration,and improving metabolic health hold promise by targeting specific molecular pathways.Other molecular signaling pathways in skeletal muscle include the canonical Wnt signaling pathway,a critical regulator of myogenesis,muscle regeneration,and metabolic function,and the Hippo signaling pathway.In recent years,more details have been uncovered about the role of these two pathways during myogenesis and in developing and adult skeletal muscle fibers,and at the neuromuscular junction.In fact,research in the last few years now suggests that these two signaling pathways are interconnected and that they jointly control physiological and pathophysiological processes in muscle fibers.In this review,we will summarize and discuss the data on these two pathways,focusing on their concerted action next to their contribution to skeletal muscle biology.However,an in-depth discussion of the noncanonical Wnt pathway,the fibro/a dipogenic precursors,or the mechanosensory aspects of these pathways is not the focus of this review. 展开更多
关键词 canonical Wnt"Wingless-related integration site"pathway beta-catenin(CTNNB1) Hippo pathway MYOGENESIS MYOTUBE neuromuscular junction satellite cell skeletal muscle fiber transcriptional co-activator with PDZ-binding motif(TAZ) T-cell-specific transcription factor/lymphoid enhancer-binding factor(TCF/LEF) TEA domain family member(TEAD) transducin-like enhancer of split(TLE) yes-associated protein 1(YAP1)
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Artificial photosynthesis for high-value-added chemicals:Old material,new opportunity 被引量:7
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作者 Sungsoon Kim Kwang Hee Kim +2 位作者 Cheoulwoo Oh Kan Zhang Jong Hyeok Park 《Carbon Energy》 SCIE CAS 2022年第1期21-44,共24页
Solar energy utilization has drawn attention due to ever-increasing environmental and energy issues.Photoelectrochemical(PEC)and photocatalytic(PC)water splitting for hydrogen production,which is the most popular and ... Solar energy utilization has drawn attention due to ever-increasing environmental and energy issues.Photoelectrochemical(PEC)and photocatalytic(PC)water splitting for hydrogen production,which is the most popular and well-established solar-to-chemical conversion process,has been studied thoroughly to date but is now facing limitations related to low conversion efficiency.To resolve this issue,research in PEC cells or photocatalysts has recently aimed to produce alternative value-added chemicals by modifying their redox reactions,which potentially enables high economic reward to compensate for the low efficiency.Here,various kinds of redox reactions that decouple classic water splitting reactions to produce value-added chemicals via PEC and PC processes are introduced.Successful coupling of CO_(2) reduction,O_(2) reduction and organic synthesis with either water oxidation or water reduction is comprehensively discussed from the perspective of basic fundamental and product selectivity in terms of the band structure of materials,cocatalyst design,and thermodynamics and kinetics of the reactions.Throughout the review,future challenges and opportunities are suggested with respect to the redesigned artificial synthesis,which might be an alternative development for the commercialization of PEC or PC value-added chemical production technologies in the near future. 展开更多
关键词 artificial photosynthesis PHOTOCATALYSTS photoelectrochemical cells redox reactions value-added chemical production
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Food processing wastewater purification by microalgae cultivation associated with high value-added compounds production——A review 被引量:3
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作者 Shuhong Li Shuang Zhao +4 位作者 Siliang Yan Yiting Qiu Chunfeng Song Yang Li Yutaka Kitamura 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2019年第12期2845-2856,共12页
Microalgae have been considered as an efficient microorganism for wastewater treatment with simultaneously bioenergy and high value-added compounds production.However,the high energy cost associated with complicated b... Microalgae have been considered as an efficient microorganism for wastewater treatment with simultaneously bioenergy and high value-added compounds production.However,the high energy cost associated with complicated biorefinery(e.g.microalgae cultivation,harvesting,drying,extraction,conversion,and purification)is a critical challenge that inhibits its large-scale application.Among different nutrition(e.g.carbon,nitrogen and phosphorous)sources,food processing wastewater is a relative safe and suitable one for microalgae cultivation due to its high organic content and low toxicity.In this review,the characteristic of different food wastewater is summarized and compared.The potential routes of value-added products(i.e.biofuel,pigment,polysaccharide,and amino acid)production along with wastewater purification are introduced.The existing challenges(e.g.biorefinery cost,efficiency and mechanism)of microalgal-based wastewater treatment are also discussed.The prospective of microalgae-based food processing wastewater treatment strategies(such as microalgae-bacteria consortium,poly-generation of bioenergy and value-added products)is forecasted.It can be observed that food wastewater treatment by microalgae could be a promising strategy to commercially realize waste source reduce,conversion and reutilization. 展开更多
关键词 Food wastewater MICROALGAE value-added PRODUCE BIOFUEL POLYSACCHARIDE Protein
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Influence of Pt/Ru anodic ratio on the valorization of ethanol by PEM electrocatalytic reforming towards value-added products 被引量:2
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作者 Alberto Rodriguez-Gomez Fernando Dorado +1 位作者 Antonio de Lucas-Consuegra Ana Raquel de la Osa 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2021年第5期264-275,共12页
The ethanol electro-reforming process was studied over PtRu/C catalysts synthesized by the modified polyol method with different compositions.In particular,this work reports the influence of anodic Pt:Ru ratio(5:1,2:1... The ethanol electro-reforming process was studied over PtRu/C catalysts synthesized by the modified polyol method with different compositions.In particular,this work reports the influence of anodic Pt:Ru ratio(5:1,2:1 and 1:2)on the organic product distribution(acetaldehyde,acetic acid and ethyl acetate)and pure hydrogen generation at different current densities operation levels.Physicochemical characterization of the catalysts was made by X-ray diffraction(XRD),temperature-programmed reduction(TPR)and N_(2) adsorption-desorption measurements.XRD patterns showed that Ru is introduced into the Pt structure,forming an alloy between both metals.Also,the degree of alloy was higher by increasing the Ru amounts.From TPR profiles Pt was found to be properly reduced while Ru was both in metallic state and forming RuO2.The electrochemical behaviour of each catalyst towards ethanol electroreforming process was investigated through electrochemical techniques in a half cell and a single proton exchange membrane(PEM)cell systems.An intermediate Pt:Ru ratio was found to result in high current density and electrochemical surface area(ECSA)values along with lower amounts of adsorbed species.Also,Ru addition seems to diminish the degree of degradation of the catalyst.Based on characterization and in agreement with essays carried out in a PEM cell at mild conditions(80℃ and 1 atm),PtRu/C 2:1 anode provided the best electrocatalytic results in terms of current density(740 mA cm^(-2)),hydrogen production and selectivity toward acetic acid(up to 15%apart from acetaldehyde and ethyl acetate)while requiring the lowest energy consumption. 展开更多
关键词 Ethanol electro-reforming PEM cell Pt:Ru anodic ratio Hydrogen production value-added liquid product distribution
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Brief analysis on value-added tax transformation and its influence on enterprises
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作者 HUANG Wei-mo 《Chinese Business Review》 2009年第2期55-58,共4页
From Jan. 1st, 2009, the value-added tax transformation will be performed in all industries around the country. Based on value-added tax types and retrospection of reform practices, this article analyzes the backgroun... From Jan. 1st, 2009, the value-added tax transformation will be performed in all industries around the country. Based on value-added tax types and retrospection of reform practices, this article analyzes the background of the national value-added tax transformation and points out the influence of full implementation of the value-added tax transformation on various enterprises. 展开更多
关键词 value-added tax value-added tax transformation production value-added tax consumption value-added tax
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Evolution trends and structural decomposition of China's green value-added over 40 years of reform and opening-up
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作者 Jin Fan Wei Wan +1 位作者 Xiaohui Yuan Fatemeh Ranaei 《Chinese Journal of Population,Resources and Environment》 2020年第2期69-78,共10页
China's 40-year history of reform and opening-up includes rapid economic development as well as pollution and environmental governance.Using a four-stage division,this study explores the evolution trend and struct... China's 40-year history of reform and opening-up includes rapid economic development as well as pollution and environmental governance.Using a four-stage division,this study explores the evolution trend and structural decomposition of China's green value-added by constructing a non-competitive input-output table for environmental pollution from 1978 to 2017.The results indicate that pollution production coefficients increased continuously,and the green value-added index decreased.Additionally,the structural decomposition showed that investment and export were critical for economic growth during the period,though they were accompanied by serious pollution problems.The pollution generated by the raw material(represented by coal mining)and processing industries(represented by the textiles)were not controlled effectively.Pollution treatment for these industries should be strengthened in the future.The study has implications for government officials,policy makers,and academics.First,China should make green development a core concept for economic development,increase environmental pollution governance,develop a“green GDP,”incorporate the external costs of environmental pollution into the national economic accounting system.Second,it must change the investment and export structure as well as the traditional economic development pattern that exacerbates pollution.Specifically,the country should develop industries with low pollution and promote the export of industries producing high value-added products and increase green GDP per capita.Third,it should closely monitor the development of highly polluting industries.Upgrading technology to reduce pollution and strengthening pollution treatment will reduce the number of polluting industries and improve environmental governance efficiency. 展开更多
关键词 Green value-added Non-competitive input-output table Factor decomposition Environmental governance
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Aldo-keto reductase family member C3(AKR1C3)promotes hepatocellular carcinoma cell growth by producing prostaglandin F2α 被引量:2
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作者 KUO-SHYANG JENG PO-YU CHENG +5 位作者 YUEH-HSIEN LIN PO-CHUN LIU PING-HUI TSENG YU-CHAO WANG CHIUNG-FANG CHANG CHUEN-MIIN LEU 《Oncology Research》 SCIE 2024年第1期163-174,共12页
Hepatocellular carcinoma(HCC)is a leading cause of death worldwide.Current therapies are effective for HCC patients with early disease,but many patients suffer recurrence after surgery and have a poor response to chem... Hepatocellular carcinoma(HCC)is a leading cause of death worldwide.Current therapies are effective for HCC patients with early disease,but many patients suffer recurrence after surgery and have a poor response to chemotherapy.Therefore,new therapeutic targets are needed.We analyzed gene expression profiles between HCC tissues and normal adjacent tissues from public databases and found that the expression of genes involved in lipid metabolism was significantly different.The analysis showed that AKR1C3 was upregulated in tumors,and high AKR1C3 expression was associated with a poorer prognosis in HCC patients.In vitro,assays demonstrated that the knockdown of AKR1C3 or the addition of the AKR1C3 inhibitor indomethacin suppressed the growth and colony formation of HCC cell lines.Knockdown of AKR1C3 in Huh7 cells reduced tumor growth in vivo.To explore the mechanism,we performed pathway enrichment analysis,and the results linked the expression of AKR1C3 with prostaglandin F2 alpha(PGF2a)downstream target genes.Suppression of AKR1C3 activity reduced the production of PGF2a,and supplementation with PGF2a restored the growth of indomethacin-treated Huh7 cells.Knockdown of the PGF receptor(PTGFR)and treatment with a PTGFR inhibitor significantly reduced HCC growth.We showed that indomethacin potentiated the sensitivity of Huh7 cells to sorafenib.In summary,our results indicate that AKR1C3 upregulation may promote HCC growth by promoting the production of PGF2α,and suppression of PTGFR limited HCC growth.Therefore,targeting the AKR1C3-PGF2a-PTGFR axis may be a new strategy for the treatment of HCC. 展开更多
关键词 Hepatocellular carcinoma Aldo-keto reductase family member C3 Prostaglandin F2 alpha Prostaglandin F receptor
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Reactive ball-milling synthesis of Co-Fe bimetallic catalyst for efficient hydrogenation of carbon dioxide to value-added hydrocarbons
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作者 Haipeng Chen Chenwei Wang +5 位作者 Mengyang Zheng Chenlei Liu Wenqiang Li Qingfeng Yang Shixue Zhou Xun Feng 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2023年第9期210-218,共9页
Catalytic hydrogenation of CO_(2) using renewable hydrogen not only reduces greenhouse gas emissions,but also provides industrial chemicals.Herein,a Co-Fe bimetallic catalyst was developed by a facile reactive ball-mi... Catalytic hydrogenation of CO_(2) using renewable hydrogen not only reduces greenhouse gas emissions,but also provides industrial chemicals.Herein,a Co-Fe bimetallic catalyst was developed by a facile reactive ball-milling method for highly active and selective hydrogenation of CO_(2) to value-added hydrocarbons.When reacted at 320℃,1.0 MPa and 9600 mL h^(-1) g_(cat)^(-1),the selectivity to light olefin(C_(2)^(=)-C_(4)^(=)) and C_(5)+ species achieves 57.3% and 22.3%,respectively,at a CO_(2) co nversion of 31.4%,which is superior to previous Fe-based catalysts.The CO_(2) activation can be promoted by the CoFe phase formed by reactive ball milling of the Fe-Co_(3)O_(4) mixture,and the in-situ Co_(2)C and Fe_(5)C_(2) formed during hydrogenation are beneficial for the C-C coupling reaction.The initial C-C coupling is related to the combination of CO species with the surface carbon of Fe/Co carbides,and the sustained C-C coupling is maintained by self-recovery of defective carbides.This new strategy contributes to the development of efficient catalysts for the hydrogenation of CO_(2) to value-added hydrocarbons. 展开更多
关键词 Reactive ball milling Co-Fe bimetallic catalyst Carbon dioxide value-added hydrocarbon C–C coupling reaction
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PoC: An IMS-based Wireless Value-added Service
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作者 Liu Xiaowen,Zhang Lijun (Department of Communication Engineering, Nanjing University of Posts and Telecommunications, Nanjing 210003, China) 《ZTE Communications》 2005年第4期21-24,共4页
This article introduces the Push-to-talk over Cellular( PoC) service, a new mobile value-added service based on the IP Multimedia Subsystem (IMS). Its implementation scheme is discussed and its Session Initiation Prot... This article introduces the Push-to-talk over Cellular( PoC) service, a new mobile value-added service based on the IP Multimedia Subsystem (IMS). Its implementation scheme is discussed and its Session Initiation Protocol (SIP) signaling exchange flow is described. Target user groups are predicted based on the analysis of the strengths and weaknesses of the PoC service. The article purports that the PoC system could undoubtedly be used as a platform for new services such as multimedia messaging, instant messaging, presence, and picture receiving and sending. Just like the short message service, the PoC service will help the terminal vendors, equipment vendors, content providers and operators setup a win-for-all industrial value chain. 展开更多
关键词 IMS FIGURE POC An IMS-based Wireless value-added Service GPP Server UMTS
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Export Value-Added of China’s Manufacturing Sector:Estimation and Mechanism Analysis
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作者 樊秀峰 程文先 《China Economist》 2015年第6期66-77,共12页
Estimation of domestic and overseas value-added of manufacturing sector is an important and difficult subject for the science-based evaluation of a country's trade interests under global value chain. Traditional HIY ... Estimation of domestic and overseas value-added of manufacturing sector is an important and difficult subject for the science-based evaluation of a country's trade interests under global value chain. Traditional HIY approach overestimates the domestic value- added of export. Although Koopman's method made certain improvements, it cannot utilize traditional I/O matrix and direct input coefficient matrix under the condition of incomplete information. By creating GAMS model, this paper addresses the above-mentioned problems and employs an improved model for the estimation of variations in domestic and overseas value-added of Chinese exports between 2002 and 2012. Our results indicate that by neglecting the export of processing trade, HIY approach overestimates the domestic value- added ratio of Chinese exports. As more imported intermediate inputs have been used in the export of processing trade, the estimation result of this paper have corrected deviations in the forecast of overseas value-added ratio and its tendencies based on HIY method Further analysis of specific factors of domestic value-added of export led to the discovery that the domestic value-added of export of processing trade and mixed trade is highly vulnerable to the impact of international capital inflow. It can be seen that the improved method for the estimation of value-added has indeed corrected the deviations in the estimation of China's value-added. In conclusion, China should accelerate the development of export of non- processing trade and trade in high-end services, and balance the relationship of export between local firms and foreign-funded firms, with a view to improving trade dependence and increasing the trade status of Chinese manufaeturing firms in global value chain. 展开更多
关键词 global value chain domestic value-added processing trade estimationapproach
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Characteristics and control factors of feldspar dissolution in gravity flow sandstone of Chang 7 Member,Triassic Yanchang Formation,Ordos Basin,NW China 被引量:1
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作者 ZHU Haihua ZHANG Qiuxia +4 位作者 DONG Guodong SHANG Fei ZHANG Fuyuan ZHAO Xiaoming ZHANG Xi 《Petroleum Exploration and Development》 SCIE 2024年第1期114-126,共13页
To clarify the formation and distribution of feldspar dissolution pores and predict the distribution of high-quality reservoir in gravity flow sandstone of the 7^(th) member of Triassic Yanchang Formation(Chang 7 Memb... To clarify the formation and distribution of feldspar dissolution pores and predict the distribution of high-quality reservoir in gravity flow sandstone of the 7^(th) member of Triassic Yanchang Formation(Chang 7 Member)in the Ordos Basin,thin sections,scanning electron microscopy,energy spectrum analysis,X-ray diffraction whole rock analysis,and dissolution experiments are employed in this study to investigate the characteristics and control factors of feldspar dissolution pores.The results show that:(1)Three types of diagenetic processes are observed in the feldspar of Chang 7 sandstone in the study area:secondary overgrowth of feldspar,replacement by clay and calcite,and dissolution of detrital feldspar.(2)The feldspar dissolution of Chang 7 tight sandstone is caused by organic acid,and is further affected by the type of feldspar,the degree of early feldspar alteration,and the buffering effect of mica debris on organic acid.(3)Feldspars have varying degrees of dissolution.Potassium feldspar is more susceptible to dissolution than plagioclase.Among potassium feldspar,orthoclase is more soluble than microcline,and unaltered feldspar is more soluble than early kaolinized or sericitized feldspar.(4)The dissolution experiment demonstrated that the presence of mica can hinder the dissolution of feldspar.Mica of the same mass has a significantly stronger capacity to consume organic acids than feldspar.(5)Dissolution pores in feldspar of Chang 7 Member are more abundant in areas with low mica content,and they improve the reservoir physical properties,while in areas with high mica content,the number of feldspar dissolution pores decreases significantly. 展开更多
关键词 gravity flow sandstone differential feldspar dissolution mica-feldspar dissolution experiment Chang 7 member of Triassic Yanchang Formation Ordos Basin
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International Competitiveness of China’s Manufacturing Sectors:Estimation Based on Trade in Value-added
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作者 戴翔 《China Economist》 2015年第6期110-122,共13页
Based on trade in value-added, this paper has estimated the revealed comparative advantage (RCA) of China's various manufacturing sectors between 1995 and 2011 and compared with the RCA indexes measured using conve... Based on trade in value-added, this paper has estimated the revealed comparative advantage (RCA) of China's various manufacturing sectors between 1995 and 2011 and compared with the RCA indexes measured using conventional aggregate accounting approach. Results indicate that: (1) the RCA index measured using conventional aggregate accounting approach has underestimated China's comparative advantage of labor-intensive sectors but overestimated China's comparative advantage in capital, knowledge and technology-intensive manufacturing sectors, giving rise to a serious misjudgment. (2) The RCA measured using value-added approach shows that in the industry chain layout of global manufacturing sectors, China's comparative advantage is still concentrated in labor-intensive manufacturing sectors but has signs of weakening; in capital, knowledge and technology-intensive sectors, China is yet to develop any significant comparative advantage; there are signs that China is developing comparative advantage in capital-intensive sectors yet China's comparative disadvantage in knowledge and technology-intensive sectors has no significant tendency to improve. This result not only helps correct the misjudgment of China's competitiveness in manufacturing sectors based on conventional aggregate accounting approach but offers important policy implications for setting strategic directions and policies for China's manufacturing transition and upgrade. 展开更多
关键词 trade in value-added international competitiveness revealed comparativeadvantage (RCA)
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Distribution of Value-added Income of Collective Construction Land Entering the Market Based on the Subject Input Contribution and TOPSIS
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作者 Chenguang YUAN Lingchao WANG 《Asian Agricultural Research》 2021年第12期19-22,共4页
In order to promote the revitalization and development of rural areas and protect the property rights of farmers,it is necessary to explore the reasonable distribution ratio of land value-added income in collective op... In order to promote the revitalization and development of rural areas and protect the property rights of farmers,it is necessary to explore the reasonable distribution ratio of land value-added income in collective operating construction land.Under the existing land value-added income distribution model,the land value-added income obtained by the government is much greater than that of village collectives,and it is difficult for village collectives and farmers to enjoy greater benefits.This distribution model is not conducive to protecting the property rights of farmers.The results show that there was a positive correlation between land value-added income and land level,that is,the higher the land level was,the higher the value-added income and its ratio to the market transaction price were.According to calculation,the reasonable distribution ratio of the value-added income of collective operating construction land entering the market among the government,village collectives and farmers was 28.6%,51.1%,and 20.3%respectively.The actual land value-added income obtained by farmers was greatly improved compared with the current situation.In actual operation,this distribution mode has universal applicability.The reform of entering the market in the future also needs to raise the standards for entering the market,explore diversified interest protection channels,and strengthen the construction of rural collective management system. 展开更多
关键词 Collective operating construction land Land value-added income Subject input contribution TOPSIS
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Operational mechanism of comprehensive benefit evaluation of existing building energy efficient renovation project based on value-added life
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作者 GUO Han-ding WEI Yong-cheng +1 位作者 CUI Si-wen ZHANG Yin-xian 《Ecological Economy》 2019年第4期280-288,共9页
The comprehensive benefit evaluation of the existing building energy efficient renovation project cannot be separated from the scientific and effective evaluation mechanism.Based on the value-added life perspective,th... The comprehensive benefit evaluation of the existing building energy efficient renovation project cannot be separated from the scientific and effective evaluation mechanism.Based on the value-added life perspective,this paper analyzes the implementation subject,standard,system and principle of the comprehensive benefit evaluation of the existing building energy efficient renovation project.It plans the process of comprehensive benefit evaluation,and builds a scientific and reasonable operation platform of evaluation system,with a view to promoting the effective implementation of the comprehensive benefit evaluation of existing building energy-saving retrofits. 展开更多
关键词 energy efficient RENOVATION existing building value-added LIFE COMPREHENSIVE BENEFIT evaluation OPERATIONAL mechanism
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MiRNA-145-5p inhibits gastric cancer progression via the serpin family E member 1-extracellular signal-regulated kinase-1/2 axis 被引量:1
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作者 Hong-Xia Bai Xue-Mei Qiu +1 位作者 Chun-Hong Xu Jian-Qiang Guo 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第5期2123-2140,共18页
BACKGROUND MicroRNAs(miRNAs)regulate gene expression and play a critical role in cancer physiology.However,there is still a limited understanding of the function and regulatory mechanism of miRNAs in gastric cancer(GC... BACKGROUND MicroRNAs(miRNAs)regulate gene expression and play a critical role in cancer physiology.However,there is still a limited understanding of the function and regulatory mechanism of miRNAs in gastric cancer(GC).AIM To investigate the role and molecular mechanism of miRNA-145-5p(miR145-5p)in the progression of GC.METHODS Real-time polymerase chain reaction(RT-PCR)was used to detect miRNA expression in human GC tissues and cells.The ability of cancer cells to migrate and invade was assessed using wound-healing and transwell assays,respectively.Cell proliferation was measured using cell counting kit-8 and colony formation assays,and apoptosis was evaluated using flow cytometry.Expression of the epithelial-mesenchymal transition(EMT)-associated protein was determined by Western blot.Targets of miR-145-5p were predicated using bioinformatics analysis and verified using a dual-luciferase reporter system.Serpin family E member 1(SERPINE1)expression in GC tissues and cells was evaluated using RT-PCR and immunohistochemical staining.The correlation between SERPINE1 expression and overall patient survival was determined using Kaplan-Meier plot analysis.The association between SERPINE1 and GC progression was also tested.A rescue experiment of SERPINE1 overexpression was conducted to verify the relationship between this protein and miR-145-5p.The mechanism by which miR-145-5p influences GC progression was further explored by assessing tumor formation in nude mice.RESULTS GC tissues and cells had reduced miR-145-5p expression and SERPINE1 was identified as a direct target of this miRNA.Overexpression of miR-145-5p was associated with decreased GC cell proliferation,invasion,migration,and EMT,and these effects were reversed by forcing SERPINE1 expression.Kaplan-Meier plot analysis revealed that patients with higher SERPINE1 expression had a shorter survival rate than those with lower SERPINE1 expression.Nude mouse tumorigenesis experiments confirmed that miR-145-5p targets SERPINE1 to regulate extracellular signal-regulated kinase-1/2(ERK1/2).CONCLUSION This study found that miR-145-5p inhibits tumor progression and is expressed in lower amounts in patients with GC.MiR-145-5p was found to affect GC cell proliferation,migration,and invasion by negatively regulating SERPINE1 levels and controlling the ERK1/2 pathway. 展开更多
关键词 Gastric cancer MicroRNA-145-5p Serpin family E member 1 Epithelial-mesenchymal transition Proliferation Extracellular signal-regulated kinase-1/2
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Value-Added Tax (VAT) on Selected Financial Transactions
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作者 Yvona Legierska 《Journal of Modern Accounting and Auditing》 2014年第8期846-852,共7页
This paper deals with the approach to imposing value-added tax (VAT) on financial transactions. The VAT is a highly harmonized consumption tax within the European Union (EU). VAT operational rules have been set do... This paper deals with the approach to imposing value-added tax (VAT) on financial transactions. The VAT is a highly harmonized consumption tax within the European Union (EU). VAT operational rules have been set down by the relevant directive of the Council of the EU. Under the directive, it is possible to select either exemption or taxation of financial transactions. Only the first option is permitted in the Czech Republic. Pros and cons of both models are described, in particular, the problems with determining the difference between financial transactions and other similar performance that must always be subject to tax. Potential lower VAT revenue or tax base assessment, as appropriate, seems to be crucial in the case of the taxation of financial transactions. 展开更多
关键词 value-added tax (VAT) financial services financial transactions reverse charge option to tax cost-sharing agreement
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Tanshinone ⅡA improves Alzheimer’s disease via RNA nuclearenriched abundant transcript 1/microRNA-291a-3p/member RAS oncogene family Rab22a axis 被引量:1
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作者 Long-Xiu Yang Man Luo Sheng-Yu Li 《World Journal of Psychiatry》 SCIE 2024年第4期563-581,共19页
BACKGROUND Alzheimer’s disease(AD)is a neurodegenerative condition characterized by oxidative stress and neuroinflammation.Tanshinone ⅡA(Tan-ⅡA),a bioactive compound isolated from Salvia miltiorrhiza plants,has sho... BACKGROUND Alzheimer’s disease(AD)is a neurodegenerative condition characterized by oxidative stress and neuroinflammation.Tanshinone ⅡA(Tan-ⅡA),a bioactive compound isolated from Salvia miltiorrhiza plants,has shown potential neuroprotective effects;however,the mechanisms underlying such a function remain unclear.AIM To investigate potential Tan-ⅡA neuroprotective effects in AD and to elucidate their underlying mechanisms.METHODS Hematoxylin and eosin staining was utilized to analyze structural brain tissue morphology.To assess changes in oxidative stress and neuroinflammation,we performed enzyme-linked immunosorbent assay and western blotting.Additionally,the effect of Tan-ⅡA on AD cell models was evaluated in vitro using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay.Genetic changes related to the long non-coding RNA(lncRNA)nuclear-enriched abundant transcript 1(NEAT1)/microRNA(miRNA,miR)-291a-3p/member RAS oncogene family Rab22a axis were assessed through reverse transcription quantitative polymerase chain reaction.RESULTS In vivo,Tan-ⅡA treatment improved neuronal morphology and attenuated oxidative stress and neuroinflammation in the brain tissue of AD mice.In vitro experiments showed that Tan-ⅡA dose-dependently ameliorated the amyloid-beta 1-42-induced reduction of neural stem cell viability,apoptosis,oxidative stress,and neuroinflammation.In this process,the lncRNA NEAT1-a potential therapeutic target-is highly expressed in AD mice and downregulated via Tan-ⅡA treatment.Mechanistically,NEAT1 promotes the transcription and translation of Rab22a via miR-291a-3p,which activates nuclear factor kappa-B(NF-κB)signaling,leading to activation of the pro-apoptotic B-cell lymphoma 2-associated X protein and inhibition of the anti-apoptotic B-cell lymphoma 2 protein,which exacerbates AD.Tan-ⅡA intervention effectively blocked this process by inhibiting the NEAT1/miR-291a-3p/Rab22a axis and NF-κB signaling.CONCLUSION This study demonstrates that Tan-ⅡA exerts neuroprotective effects in AD by modulating the NEAT1/miR-291a-3p/Rab22a/NF-κB signaling pathway,serving as a foundation for the development of innovative approaches for AD therapy. 展开更多
关键词 TanshinoneⅡA Alzheimer’s disease Nuclear-enriched abundant transcript 1 member of RAS oncogene family Rab22a Reactive oxygen species
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"Add-ons" to the Value-Added of ELTs
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作者 Srinivasa Rao Idapalapati 《Sino-US English Teaching》 2014年第1期1-12,共12页
Teacher evaluations intend to cultivate quality among teachers. However, since they are traditionally dependent on observers and their reports that are likely biased, the procedures probably effectuate discords among ... Teacher evaluations intend to cultivate quality among teachers. However, since they are traditionally dependent on observers and their reports that are likely biased, the procedures probably effectuate discords among the calling-teaching professionals. An evaluation procedure that can ascertain fairness in the decisions about teacher retentions, terminations, promotions, and sanctions can capture the accordance of all teachers and teacher facilitators. This paper identifies the possibility of such an evaluation system that is built upon the existing value-added methods. Drawing upon the observations and recommendations by Chetty, Friedman, and Rockoff (2012) on value-added methods of evaluation, and considering the uniqueness of ELTs (English Language Teachers) as it was observed by Borg (2006) and Lee (2010), this paper describes the application of the value-added evaluation method, in gauging the quality of ELTs. The paper further explicates the vantages and conformities embodied in the procedure that could boost up the morale of ELTs as independent professionals of a creative art, and help them perform to their fullest potential 展开更多
关键词 teachers' accountability learning outcomes VA value-added self-assertion of performances measuring PD (Professional Development)
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