Building Information Modeling-Based Secondary Development System for 3D Modeling of Underground Pipelines

Underground pipeline networks constitute a major component of urban infrastructure,and thus,it is imperative to have an efficient mechanism to manage them.This study introduces a secondary development system to efficiently model underground pipeline networks,using the building information modeling(BIM)-based software Revit.The system comprises separate pipe point and tubulation models.Using a Revit application programming interface(API),the spatial position and attribute data of the pipe points are extracted from a pipeline database,and the corresponding tubulation data are extracted from a tubulation database.Using the Family class in Revit API,the cluster in the self-built library of pipe point is inserted into the spatial location and the attribute data is added;in the same way,all pipeline instances in the pipeline system are created.The extension and localization of the model accelerated the modeling speed.The system was then used in a real construction project.The expansion of the model database and rapid modeling made the application of BIM technology in three-dimensional visualization of underground pipeline networks more convenient.Furthermore,it has applications in pipeline engineering construction and management.

Searching for Novel Targets to Control Wheat Head Blight Disease—I-Protein Identification, 3D Modeling and Virtual Screening

Fusarium head blight (FHB) is a destructive disease of wheat and other cereals. FHB occurs in Europe, North America and around the world causing significant losses in production and endangers human and animal health. In this article, we provide the strategic steps for the specific target selection for the phytopathogen system wheat-Fusarium graminearum. The economic impact of FHB leads to the need for innovation. Currently used fungicides have been shown to be effective over the years, but recently cereal infecting Fusaria have developed resistance. Our work presents a new perspective on target selection to allow the development of new fungicides. We developed an innovative approach combining both genomic analysis and molecular modeling to increase the discovery for new chemical compounds with both safety and low environmental impact. Our protein targets selection revealed 13 candidates with high specificity, essentiality and potentially assayable with a favorable accessibility to drug activity. Among them, three proteins: trichodiene synthase, endoglucanase-5 and ERG6 were selected for deeper structural analyses to identify new putative fungicides. Overall, the bioinformatics filtering for novel protein targets applied for agricultural purposes is a response to the demand for chemical crop protection. The availability of the genome, secretome and PHI-base allowed the enrichment of the search that combined experimental data in planta. The homology modeling and molecular dynamics simulations allowed the acquisition of three robust and stable conformers. From this step, approximately ten thousand compounds have been virtually screened against three candidates. Forty-five top-ranked compounds were selected from docking results as presenting better interactions and energy at the binding pockets and no toxicity. These compounds may act as inhibitors and lead to the development of new fungicides.

3D bioprinting of in vitro porous hepatoma models:establishment,evaluation,and anticancer drug testing

Traditional tumor models do not tend to accurately simulate tumor growth in vitro or enable personalized treatment and are particularly unable to discover more beneficial targeted drugs.To address this,this study describes the use of threedimensional(3D)bioprinting technology to construct a 3D model with human hepatocarcinoma SMMC-7721 cells(3DP-7721)by combining gelatin methacrylate(GelMA)and poly(ethylene oxide)(PEO)as two immiscible aqueous phases to form a bioink and innovatively applying fluorescent carbon quantum dots for long-term tracking of cells.The GelMA(10%,mass fraction)and PEO(1.6%,mass fraction)hydrogel with 3:1 volume ratio offered distinct pore-forming characteristics,satisfactorymechanical properties,and biocompatibility for the creation of the 3DP-7721 model.Immunofluorescence analysis and quantitative real-time fluorescence polymerase chain reaction(PCR)were used to evaluate the biological properties of the model.Compared with the two-dimensional culture cell model(2D-7721)and the 3D mixed culture cell model(3DM-7721),3DP-7721 significantly improved the proliferation of cells and expression of tumor-related proteins and genes.Moreover,we evaluated the differences between the three culture models and the effectiveness of antitumor drugs in the three models and discovered that the efficacy of antitumor drugs varied because of significant differences in resistance proteins and genes between the three models.In addition,the comparison of tumor formation in the three models found that the cells cultured by the 3DP-7721 model had strong tumorigenicity in nude mice.Immunohistochemical evaluation of the levels of biochemical indicators related to the formation of solid tumors showed that the 3DP-7721 model group exhibited pathological characteristics of malignant tumors,the generated solid tumors were similar to actual tumors,and the deterioration was higher.This research therefore acts as a foundation for the application of 3DP-7721 models in drug development research.

Unified Data Model of Urban Air Pollution Dispersion and 3D Spatial City Model:Groundwork Assessment towards Sustainable Urban Development for Malaysia

Understanding the behavior of urban air pollution is important en route for sustainable urban development (SUD). Malaysia is on its mission to be a developed country by year 2020 comprehends dealing with air pollution is one of the indicators headed towards it. At present monitoring and managing air pollution in urban areas encompasses sophisticated air quality modeling and data acquisition. However, rapid developments in major cities cause difficulties in acquiring the city geometries. The existing method in acquiring city geometries data via ground or space measurement inspection such as field survey, photogrammetry, laser scanning, remote sensing or using architectural plans appears not to be practical because of its cost and efforts. Moreover, air monitoring stations deployed are intended for regional to global scale model whereby it is not accurate for urban areas with typical resolution of less than 2 km. Furthermore in urban areas, the pollutant dispersion movements are trapped between buildings initiating it to move vertically causing visualization complications which imply the limitations of existing visualization scheme that is based on two-dimensional (2D) framework. Therefore this paper aims is to perform groundwork assessment and discuss on the current scenario in Malaysia in the aspect of current policies towards SUD, air quality monitoring stations, scale model and detail discussion on air pollution dispersion model used called the Operational Street Pollution Model (OSPM). This research proposed the implementation of three-dimensional (3D) spatial city model as a new physical data input for OSPM. The five Level of Details (LOD) of 3D spatial city model shows the scale applicability for the dispersion model implementtation. Subsequently 3D spatial city model data commonly available on the web, by having a unified data model shows the advantages in easy data acquisition, 3D visualization of air pollution dispersion and improves visual analysis of air quality monitoring in urban areas.

Fabrication of polyetheretherketone(PEEK)-based 3D electronics with fine resolution by a hydrophobic treatment assisted hybrid additive manufacturing method

Additive manufacturing(AM)is a free-form technology that shows great potential in the integrated creation of three-dimensional(3D)electronics.However,the fabrication of 3D conformal circuits that fulfill the requirements of high service temperature,high conductivity and high resolution remains a challenge.In this paper,a hybrid AM method combining the fused deposition modeling(FDM)and hydrophobic treatment assisted laser activation metallization(LAM)was proposed for manufacturing the polyetheretherketone(PEEK)-based 3D electronics,by which the conformal copper patterns were deposited on the 3D-printed PEEK parts,and the adhesion between them reached the 5B high level.Moreover,the 3D components could support the thermal cycling test from-55℃ to 125℃ for more than 100 cycles.Particularly,the application of a hydrophobic coating on the FDM-printed PEEK before LAM can promote an ideal catalytic selectivity on its surface,not affected by the inevitable printing borders and pores in the FDM-printed parts,then making the resolution of the electroless plated copper lines improved significantly.In consequence,Cu lines with width and spacing of only60μm and 100μm were obtained on both as-printed and after-polished PEEK substrates.Finally,the potential of this technique to fabricate 3D conformal electronics was demonstrated.

Customized Visualizations of Urban Infill Development Scenarios for Local Stakeholders

Infill development has been seen as one of the solutions to urban challenges. However, it changes the dynamics and visual appearance of the neighborhood. As infill development usually requires the acceptance of local stakeholders, their perceptions of the resulting intensified housing have a significant role. In this study, customized visualizations illustrating scenarios of infill development were made from the perspective of individual apartments in neighboring residential building. The usefulness of customized visualizations for local stakeholders was studied in the Tammela test area. A 3D virtual model of the existing environment was created. Models depicting the alternative infill buildings were added to the 3D model, which was used to create customized visualizations. These visualizations were utilized in the interviews of local stakeholders. The findings indicate that the customized visualizations help stakeholders conceptualize the impact, and plan and manage the infill development. Visualizations can also be seen as a tool for a resident-driven approach to intensifying housing.

Extended research of showing means of GIS in the development and management of oil and gas reservoir

Owing to the close correlation of development of oil and gas reservoir and spatial geological place, the technique of GIS can be introduced into the process of development and management of oil and gas reservoir. But development of oil and gas reservoir has its particularity, development and management GIS of oil and gas reservoir should use the other techniques to extend the forms of representation to make up the shortages of GIS in representation. The development and management GIS of oil and gas reservoir will be perfect besides the basic functions of GIS. This paper expatiates how to use other techniques to extend GIS in development and management of oil and gas reservoir mainly from productive dynamic curve of well, layers of map piling up, 3 D geological model and replaying maps, etc. Through extended GIS in development and management of oil and gas reservoir, the forms of representation of geological information are enriched, representations of information are more direct and visual, spatial descriptive ability and forms of representation of GIS are built up and the single information system will be developed into a management and decision making system.

An intermittent lithium deposition model based on CuMnbimetallic MOF derivatives for composite lithium anode with ultrahigh areal capacity and current densities

Recently,three-dimensional(3D)conductive frameworks have been chosen as the host for composite lithium(Li)metal anode because of their exceptional electrical conductivity and remarkable thermal and electrochemical stability.However,Li tends to accumulate on the top of the 3D frameworks with homogenous lithiophilicity and Li dendrite still growth.This work firstly designed a bimetallic metal-organic framework(MOF)(CuMn-MOF)derived Cu_(2)O and Mn_(3)O_(4) nanoparticles decorated carbon cloth(CC)substrates(CC@Cu_(2)O/Mn_(3)O_(4))to fabricate a composite Li anode.Thanks to the synergistic effects of lithiophilic Cu_(2)O and Mn_(3)O_(4),the CC@Cu_(2)O/Mn_(3)O_(4)@Li symmetrical cell can afford a prolonged cycling lifespan(1400 h)under an ultrahigh current density and areal capacity(6 mA·cm^(-2)/6 mAh·cm^(-2)).When coupled with the LiFePO_(4)(LFP)cathode,the LFP||CC@Cu_(2)O/Mn_(3)O_(4)@Li full cell demonstrated a superior performance of 89.7 mAh·g^(-1) even at an extremely high current density(10 C).Furthermore,it can also be matched well with LiNi_(0.5)Co^(0).2Mn_(0.3)O_(2)(NCM523)cathode.Importantly,to explain the excellent performances of the CC@Cu_(2)O/Mn_(3)O_(4)@Li composite anode,an intermittent model was also proposed.This study offers a novel model that can enhance our comprehension of the Li deposition behavior and pave the way to attain stable and safe Li metal anodes by employing bimetallic MOF-derived materials to construct 3D frameworks.

An intermittent lithium deposition model based on bimetallic MOFs derivatives for dendrite-free lithium anode with ultrahigh areal capacity

In the development of 3D conductive frameworks for lithium metal anode(LMA),two models have been proposed:top growth model and bottom-up growth model.However,Li tends to accumulate on the top of these 3D frameworks with homogenous lithiophilicity(top growth)and Li dendrite still forms.To address this issue,some researchers have focused on developing 3D frameworks with gradient lithio-philicity,which realized bottom-up growth of Li.Nevertheless,partial Li nucleation sites on the top of these frameworks were missed.Inspired by the two models talked above,this work firstly proposed a novel intermittent lithiophilic model for lithium deposition.To demonstrate the feasibility of this model,a bimetallic metal-organic frameworks derived ZnMn_(2)O_(4)-MnO nanoparticles were grown on carbon cloth for LMA.It can cycle stably under ultra-high current and areal capacity(10 mA/cm^(2),10 mAh/cm^(2)).The in-situ optical microscopy(OM)was conducted to observe the Li deposition behavior,no dendrite was found during 80 h in ester-based electrolyte while the pure Li only cycled for 2h.What is more,it can also be well-coupled with LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2)(NCM811)cathode and solid-state electrolyte,which further prove the advantages of the intermittent model for the development of LMAs with high safety and high energy density.

Micromechanical modeling of longitudinal tensile behavior and failure mechanism of unidirectional carbon fiber/aluminum composites involving fiber strength dispersion

This paper examines the longitudinal tensile behavior and failure mechanism of a new unidirectional carbon fiber reinforced aluminum composite through experiments and simulations.A Weibull distribution model was established to describe the fiber strength dispersion based on single-fiber tensile tests for carbon fibers extracted from the composite.The constitutive models for the matrix and interface were established based on the uniaxial tensile and single-fiber push-out tests,respectively.Then,a 3D micromechanical numerical model,innovatively considering the fiber strength dispersion by use of the weakest link and Weibull distribution theories,was estab-lished to simulate the progressive failure behavior of the composite under longitudinal tension.Due to the dispersion of fiber strength,the weakest link of the fiber first fractures,and stress concentra-tion occurs in the surrounding fibers,interfaces,and matrix.The maximum stress concentration fac-tor for neighboring fibers varies nonlinearly with the distance from the fractured fiber.Both isolated and clustered fractured fibers are present during the progressive failure process of the composite.The expansion of fractured fiber clusters intensifies stress concentration and material degradation which in turn enlarges the fractured fiber clusters,and their mutual action leads to the final collapse of the composite.

A comprehensive review of 3D cancer models for drug screening and translational research

The 3D cancer models fill the discovery gap of 2D cancer models and play an important role in cancer research.In addition to cancer cells,a range of other factors include the stroma,density and composition of extracellular matrix,cancer-associated immune cells(e.g.,cancer-associated fibroblasts cancer cell-stroma interactions and subsequent interactions,and a number of other factors(e.g.,tumor vasculature and tumor-like microenvironment in vivo)has been widely ignored in the 2D concept of culture.Despite this knowledge,the continued use of monolayer cell culture methods has led to the failure of a series of clinical trials.This review discusses the immense importance of tumor microenvironment(TME)recapitulation in cancer research,prioritizing the individual roles of TME elements in cancer histopathology.The TME provided by the 3D model fulfills the requirements of in vivo spatiotemporal arrangement,components,and is helpful in analyzing various different aspects of drug sensitivity in preclinical and clinical trials,some of which are discussed here.Furthermore,it discusses models for the co-assembly of different TME elements in vitro and focuses on their synergistic function and responsiveness as tumors.Furthermore,this review broadly describes of a handful of recently developed 3D models whose main focus is limited to drug development and their screening and/or the impact of this approach in preclinical and translational research.

The Integrated 3D As-Built Representation of Underground MRT Construction Sites

This study facilitates the scalability of as-built data from an earlier street level to underground transportation sites from the life-cycle perspective of urban information maintenance. As-built 3D scans of a 6 km street were made at different time periods, and of 3 underground Mass Rapid Transit (MRT) stations under construction in Taipei. A scanned point cloud was used to create a Building Information Modeling (BIM) Level of Development (LOD) 500 as-built point cloud model, with which topographic utility data were integrated and the model quality was investigated. The complex underground models of the transportation stations are proofed to be in correct relative locations to the street entrances on ground level. In the future the 3D relationship around the station will facilitate new designs or excavations in the neighborhood urban environment.

开孔泡沫金属传热和流动特性

近年来开孔泡沫金属运用于散热设备逐渐成为研究的热点。由于开孔泡沫金属结构复杂无序,数值模拟时大都将其结构进行化简,目前已有种类繁多的简化模型,然而适用于其传热与流动特性模拟研究的简化模型尚不明确;另外,适用于散热领域的泡沫金属结构参数有待详细研究。为此,建立开孔泡沫金属的5种简化三维模型,并进行传热和流动特性的对比研究,认为Gibson-Ashby模型更能准确描述实际开孔泡沫金属的传热和流动性能。在此基础上,采用Gibson-Ashby模型对开孔泡沫金属的关键结构参数进行传热和流动综合性能分析,发现孔隙率90%、孔密度30PPI开孔泡沫金属翅片的综合性能j/f^(1/3)(j为换热因子,f为阻力因子)最优;将孔隙率90%、孔密度30PPI开孔泡沫金属翅片与平直翅片进行对比,发现开孔泡沫金属翅片换热效果是平直翅片的2倍以上,综合性能也优于平直翅片。所得研究成果可为开孔泡沫金属在换热领域的应用和设计提供参考。

SolidWorks实现渐开线齿轮三维建模

推导出直角坐标系下渐开线齿轮齿廓线方程,利用SolidWorksAPI编写了生成渐开线圆柱齿轮三维实体模型的程序,设计了输入齿轮基本参数的表单界面,使得渐开线三维模型的建立变得非常简单。同时对进行SolidWorks二次开发一般过程进行了介绍。

基于SolidWorks的圆柱齿轮设计系统研究

针对SolidWorks齿轮建模过程繁琐及效率低等问题,本文基于Visual Basic程序语言中的SolidWorks,对圆柱齿轮参数化设计系统进行研究。以Windows为开发平台,利用Visual Basic程序语言,通过对SolidWorks进行二次开发,完成了直齿、斜齿和圆柱齿轮的三维模型设计系统。该系统主要包括参数设计和三维建模两大模块,且三者之间相互联系统一,在参数设计过程中添加了疲劳强度校核部分,以实现集设计、校核于一体的圆柱齿轮三维造型系统。设计实例表明,该系统实现了齿轮的参数化设计,设计结果准确,生成的三维模型合乎要求,提高了设计效率,而且该系统用户界面形象直观,具有人性化,保证了设计的合理性与准确性。该研究对其他类型齿轮及标准件的参数化设计具有重要的参考价值。

CAD三维实体造型对企业产品研发能力的影响

目前,CAD的应用是一个企业产品研发过程中必不可少的。对企业产品的研发流程以及产品研发过程中二维CAD应用存在的主要问题进行了研究,阐述了三维图形软件的应用以及CAE软件的应用对企业产品研发能力的影响。

Zoning assessment of water environmental supporting capacity for socioeconomic development in the Huaihe River Basin, China

There have been substantial conflicts in the human-water relationship in the Huaihe River Basin （HRB）. To achieve sustainable economic development without degrading the water environment in the HRB, we develop a three-dimensional water environmental sup- porting capacity （WESC） model based on water environmental carrying capacity （WECC）, water environmental pressure （WEP）, and water pollution prevention and control capacity （WPPC）. Geographic information systems spatial analysis with the analytical hierarchy process method and dynamic weighted summation is applied. Several proposals for suitable locations for industry and environmental protection strategies for water were presented. The following results were obtained. （1） The spatial differences in WECC are substantial; areas with high-value WECC zones are mainly located along the main stream of the Huaihe River on the south side. WEP is generally high, with an overall low level of pollution prevention and control in the whole HRB. WPPC and WEP show high spatial overlapping due to the fact that areas with higher environmental pollution usually have high level of economic development, and thus have a strong capacity for pollution control. （2） Overall, WESC is moderate in the HRB. In particular, areas with a high WESC value only account for 56.24% of the HRB in 2010 Distinct differences in WESC also exist between areas located in the south compared with in the north of the basin, and areas alongside the downstream region compared with alongside the upstream and midstream regions. （3） Consequently, according to the guidance for indus- try zoning in the HRB, the areas in the south and alongside the downstream and sub-streams with a low WEP value and high WECC and WPPC, traditional industries should be developed based on strict environmental access and pollution emission standards. While for the areas along the midstream of the HRB and along the whole Yishusi River Basin, which have a high WEP value, industrial restructuring and technological upgrading are suggested. Action should be taken to limit development and protect the environment in the upstream region of the basin which is a key source of drinking water, in the eastern route along the line of the South-toNorth Water Diversion Project, and in the ecologically fragile region alongside the basin. This will ensure good environmental functionality including subsistent provision of clean water, while at the same time satisfying the urgent need to adjust, transform, and upgrade the industrial structure.

Local electronic structure and magnetic properties of 3d transition metal doped GaAs

The local electronic structure and magnetic properties of GaAs doped with 3d transition metal (Sc, Ti, V, Cr, Mn, Fe, Co, Ni) were studied by using discrete variational method (DVM) based on density functional theory. The calculated result indicated that the magnetic moment of transition metal increases first and then decreases, and reaches the maximum value when Mn is doped into GaAs. In the case of Mn concentration of 1.4%, the magnetic moment of Mn is in good agreement with the experimental result. The coupling between impure atoms in the system with two impure atoms was found to have obvious variation. For different transition metal, the coupling between the impure atom and the nearest neighbor As also has different variation.

虚拟三维服装展示的发展历史与研究热点

虚拟三维服装展示涉及众多学科领域的技术融合,致力于产生逼真而富有动感的展示效果。20世纪80年代中后期以来,虚拟三维服装仿真技术经历了从简单织物变形形态的静态模拟到三维复杂服装动态模拟的过程。对织物以及服装的模拟主要归结于建模技术与数值方法的结合,不同的织物服装有不同的建模技术,对于同种模型,不同的数值计算方法的计算效率也不尽相同。从建模技术、数值理论、碰撞检测和响应等方面,系统地介绍织物形态模拟技术和虚拟三维服装展示技术的发展历史,详细地分析三维服装展示技术面临的挑战、近期的研究热点和未来发展趋势。

井地电法三维物理模型试验

文中通过采用不锈钢管模拟金属套管,细铜棒模拟供电电极,高阻绝缘板代表油层,紫铜板代表水层,并利用128道网络电位记录仪器水槽模拟实验,获得单一模型、横向和纵向组合模型的地面电位异常。通过研究钢套管井中供电存在高阻或低阻异常体时,地面电位等值线异常规律,可为井地电法研究油气储层或水层提供物理依据。模拟实验结果表明,通过向油井中供直流电,在水(地)面测量电场分布的井地工作方式的直流充电法,对于目标油气藏能够有效地消除其上方电性不均匀的影响,特别是对于上、下几套油水层同时存在,且层与层之间存在一定距离时,井地电法有可能圈定出不同储层的分布范围。因此,此法有可能在油田开发和注水开采中监测以及寻找剩余油气分布发挥重要作用。