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Hypobaric-hypoxia Induces Alteration in Microbes and Microbes-associated Enzyme Profile in Rat Colonic Samples 被引量:4
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作者 Chiranjit MAITY Atanu ADAK +2 位作者 Kuntal GHOSH Bikas R PATI Keshab C MONDAL 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2013年第10期869-873,共5页
Present study deals with the straight impact of hypobaric hypoxia on the quantity and composition of some predominant fecal microflora and its functional aspects. For that, isolated fecal contents of rat were exposed ... Present study deals with the straight impact of hypobaric hypoxia on the quantity and composition of some predominant fecal microflora and its functional aspects. For that, isolated fecal contents of rat were exposed to two different simulated air pressures (70 kPa and 40 kPa) for different time durations (1, 3, and 5 h) and the bacterial community composition was compared with normobaric groups (101.3 kPa). It was found that the total anaerobes, Escherichio coli, Enterbocters spp., Bi^idobocterium spp., CIostridium spp. were increased whereas total aerobes were decreased at both hypobaric treatments. The increased number of amplicon was detected in the pressure-treated groups than the control that clearly mentioned the disruption of microbiota structure at different simulated hypobaric-hypoxia. The amylase, protease, tannase, 13-glucuronidase, and alkaline phosphatase activities were increased at these atmospheric pressures. Thus, the present investigation demonstrates that the hypobaric hypoxia is an important environmental factor which can strongly modulate the composition of intestinal flora as well as microfiora-derived functional aspects. 展开更多
关键词 Hypobaric-hypoxia Induces Alteration in Microbes and microbes-associated Enzyme Profile in Rat Colonic Samples
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