To explore the application of the characteristics of metallic microparticles, alternating current electric trapping of the SU-8 microrods coated with a thin gold layer by the chemical approach is investigated. Positiv...To explore the application of the characteristics of metallic microparticles, alternating current electric trapping of the SU-8 microrods coated with a thin gold layer by the chemical approach is investigated. Positive dielectrophoresis is used to absorb the gold-coated SU-8 microrods at the edge of the parallel electrodes, thereby forming chains to connect the electrodes. This is a fast automatic microcircuit formation process. Moreover, a non-charged molecule is modified on the surface of the gold-coated SU-8 microrod, and the modified microrods are controlled by the alternating electric field to form a number of chains. The different chains between the parallel electrodes consist of various parallel circuits. In order to compare these chains with different electric surfaces, the impedances of the metallic and modified microrods are measured and compared, and the results show that the gold-coated microrods act as pure resistors, while the microrods functionalized by a non-charged molecule behave as good capacitors.展开更多
Extremely low-frequency magnetic field is widely used as a noninvasive stimulation method in clinical practice and basic research. Electrical field induced from magnetic pulse can decrease or increase neuronal electri...Extremely low-frequency magnetic field is widely used as a noninvasive stimulation method in clinical practice and basic research. Electrical field induced from magnetic pulse can decrease or increase neuronal electrical activity. However, the cellular mechanism underlying the effects of magnetic field is not clear from experimental data. Recent studies have demonstrated that "non-neuronal" cells, especially astrocytes, may be the potential effector for transcranial magnetic stimulation(TMS). In the present study, we implemented a neural–astrocyte microcircuit computational model based on hippocampal architecture to investigate the biological effects of different magnetic field frequencies on cells. The purpose of the present study is to elucidate the main influencing factors of MS to allow a better understanding of its mechanisms.Our model reproduced the basic characteristics of the neuron and astrocyte response to different magnetic stimulation. The results predict that interneurons with lower firing thresholds were more active in magnetic fields by contrast to pyramidal neurons. And the synaptic coupling strength between the connected neurons may be one of the critical factor to affect the effect of magnetic field on cells. In addition, the simulations show that astrocytes can decrease or increase slow inward currents(SICs) to finely tune neuronal excitation, which suggests their key role in excitatory–inhibitory balance. The interaction between neurons and astrocytes may represent a novel target for effective therapeutic strategies involving magnetic stimulation.展开更多
Positive type photosensitive polyimide is used as the modification layer in the thin film transistors production process. The photosensitive polyimide is not only used as the second insulating layer, it can also be us...Positive type photosensitive polyimide is used as the modification layer in the thin film transistors production process. The photosensitive polyimide is not only used as the second insulating layer, it can also be used instead of a mask because of the photosensitivity. A suitable curing condition can help photosensitive polyimide form the high performance polyimide with orderly texture inside, and the performance of imidization depends on the precise control of temperature, time, and heat control during the curing process. Therefore, experiments of different stepped up heating tests are made, and the ability of protecting silicon dioxide is analyzed.展开更多
With the support by the National Natural Science Foundation of China,the research team led by Prof.Yu Yongchun(禹永春)at the Institutes of Brain Science,Fudan University,revealed the vital roles of electrical coupling...With the support by the National Natural Science Foundation of China,the research team led by Prof.Yu Yongchun(禹永春)at the Institutes of Brain Science,Fudan University,revealed the vital roles of electrical coupling in chemical synapse formation between interneurons,which was published in Nature Communications(2016,7:12229,DOI:10.1038).Although the excitatory neurons in the neocortex are electrically coupled only during early development,展开更多
根据我国海洋综合气象监测装备建设网点不继扩大和加密的现状,依靠现有的卫星通信网络,利用其覆盖范围广、通信稳定、实时在线和维持经费等优势,设计一种基于卫星通信网络的海洋气象数据采集系统。介绍该系统的数据采集结构和功能,智能...根据我国海洋综合气象监测装备建设网点不继扩大和加密的现状,依靠现有的卫星通信网络,利用其覆盖范围广、通信稳定、实时在线和维持经费等优势,设计一种基于卫星通信网络的海洋气象数据采集系统。介绍该系统的数据采集结构和功能,智能处理终端的硬件组成,硬件电路芯片选型与使用;介绍系统软件的控制和编制方法,简述在可视化编程语言Microsoft Visual Studio 6.0集成包环境下开发海洋气象数据采集系统软件的步骤;讨论基于我国北斗卫星通信网络的海洋气象数据采集系统的实际应用情况。展开更多
根据我国实时监测气象设备布设网点不断扩大和加密的现状,提出利用现有的GPRS网络覆盖范围广、实时在线、通信质量高和维持费用低等优势,设计一种基于GPRS网络的远程气象数据采集系统。介绍该系统的结构模式和功能,系统中远程测控终端...根据我国实时监测气象设备布设网点不断扩大和加密的现状,提出利用现有的GPRS网络覆盖范围广、实时在线、通信质量高和维持费用低等优势,设计一种基于GPRS网络的远程气象数据采集系统。介绍该系统的结构模式和功能,系统中远程测控终端的硬件结构组成,相关的电路芯片使用。阐述编制相应控制软件的方法,在Microsoft Visual Studio 6.0可视化编程语言集成包环境下开发管理中心软件的方法,以及基于GPRS网络的远程气象数据采集系统的实际应用情况。展开更多
基金supported by the National Natural Science Foundation of China(Grant No.51075087)the Funds from the State Key Laboratory of Fluid Power Transmission and Control,Zhejiang University,China(Grant Nos.GZKF-201107 and GZKF-201004)the Foundation from the China Scholarship Council(Grant No.2009612129)
文摘To explore the application of the characteristics of metallic microparticles, alternating current electric trapping of the SU-8 microrods coated with a thin gold layer by the chemical approach is investigated. Positive dielectrophoresis is used to absorb the gold-coated SU-8 microrods at the edge of the parallel electrodes, thereby forming chains to connect the electrodes. This is a fast automatic microcircuit formation process. Moreover, a non-charged molecule is modified on the surface of the gold-coated SU-8 microrod, and the modified microrods are controlled by the alternating electric field to form a number of chains. The different chains between the parallel electrodes consist of various parallel circuits. In order to compare these chains with different electric surfaces, the impedances of the metallic and modified microrods are measured and compared, and the results show that the gold-coated microrods act as pure resistors, while the microrods functionalized by a non-charged molecule behave as good capacitors.
基金supported by the National Natural Science Foundation of China (Grant No. 61673158)the Youth Talent Support Program of Hebei Province,China(Grant No. BJ2019044)。
文摘Extremely low-frequency magnetic field is widely used as a noninvasive stimulation method in clinical practice and basic research. Electrical field induced from magnetic pulse can decrease or increase neuronal electrical activity. However, the cellular mechanism underlying the effects of magnetic field is not clear from experimental data. Recent studies have demonstrated that "non-neuronal" cells, especially astrocytes, may be the potential effector for transcranial magnetic stimulation(TMS). In the present study, we implemented a neural–astrocyte microcircuit computational model based on hippocampal architecture to investigate the biological effects of different magnetic field frequencies on cells. The purpose of the present study is to elucidate the main influencing factors of MS to allow a better understanding of its mechanisms.Our model reproduced the basic characteristics of the neuron and astrocyte response to different magnetic stimulation. The results predict that interneurons with lower firing thresholds were more active in magnetic fields by contrast to pyramidal neurons. And the synaptic coupling strength between the connected neurons may be one of the critical factor to affect the effect of magnetic field on cells. In addition, the simulations show that astrocytes can decrease or increase slow inward currents(SICs) to finely tune neuronal excitation, which suggests their key role in excitatory–inhibitory balance. The interaction between neurons and astrocytes may represent a novel target for effective therapeutic strategies involving magnetic stimulation.
文摘Positive type photosensitive polyimide is used as the modification layer in the thin film transistors production process. The photosensitive polyimide is not only used as the second insulating layer, it can also be used instead of a mask because of the photosensitivity. A suitable curing condition can help photosensitive polyimide form the high performance polyimide with orderly texture inside, and the performance of imidization depends on the precise control of temperature, time, and heat control during the curing process. Therefore, experiments of different stepped up heating tests are made, and the ability of protecting silicon dioxide is analyzed.
文摘With the support by the National Natural Science Foundation of China,the research team led by Prof.Yu Yongchun(禹永春)at the Institutes of Brain Science,Fudan University,revealed the vital roles of electrical coupling in chemical synapse formation between interneurons,which was published in Nature Communications(2016,7:12229,DOI:10.1038).Although the excitatory neurons in the neocortex are electrically coupled only during early development,
文摘根据我国海洋综合气象监测装备建设网点不继扩大和加密的现状,依靠现有的卫星通信网络,利用其覆盖范围广、通信稳定、实时在线和维持经费等优势,设计一种基于卫星通信网络的海洋气象数据采集系统。介绍该系统的数据采集结构和功能,智能处理终端的硬件组成,硬件电路芯片选型与使用;介绍系统软件的控制和编制方法,简述在可视化编程语言Microsoft Visual Studio 6.0集成包环境下开发海洋气象数据采集系统软件的步骤;讨论基于我国北斗卫星通信网络的海洋气象数据采集系统的实际应用情况。
文摘根据我国实时监测气象设备布设网点不断扩大和加密的现状,提出利用现有的GPRS网络覆盖范围广、实时在线、通信质量高和维持费用低等优势,设计一种基于GPRS网络的远程气象数据采集系统。介绍该系统的结构模式和功能,系统中远程测控终端的硬件结构组成,相关的电路芯片使用。阐述编制相应控制软件的方法,在Microsoft Visual Studio 6.0可视化编程语言集成包环境下开发管理中心软件的方法,以及基于GPRS网络的远程气象数据采集系统的实际应用情况。
