A buttress on the need for welfare program in Nigeria and the important obligation to consider the Economics’and CIA’s contextual position for the dependency ratios,both total and elderly dependency ratio alongside ...A buttress on the need for welfare program in Nigeria and the important obligation to consider the Economics’and CIA’s contextual position for the dependency ratios,both total and elderly dependency ratio alongside the consideration of the age structure and demography statistics of Nigeria relatively to other economies,particularly as an elixir for the declining older population in Nigeria and the aged male contraction in the nation.Although,older female population is higher in every country as obtainable globally,the Nigerian case is that of drastic contraction in both aged male and older population generally.Therefore,the submission is that the government has to consider the total dependency ratio to the elderly dependency ratio,which is all-encompassing in order to cater for the declining older population and to appropriate the requisite welfare cum benefits programs in the nation.展开更多
1.Introduction With the increase in older populations worldwide1 comes an increased health burden related to chronic diseases.2–4One of the most disabling of these is knee osteoarthritis(OA),which occurs in million...1.Introduction With the increase in older populations worldwide1 comes an increased health burden related to chronic diseases.2–4One of the most disabling of these is knee osteoarthritis(OA),which occurs in millions of older adults who subsequently live with joint pain and stiffness,leading to chronic disability and a diminished quality of life.5,6 Epidemiological evidence shows a higher prevalence of OA in older adults living in urban and展开更多
BACKGROUND Spinal anesthesia is superior to general anesthesia for postoperative recovery in older patients(≥65 age).However,evidence for this is lacking.AIM To evaluate the effect of anesthesia on postoperative comp...BACKGROUND Spinal anesthesia is superior to general anesthesia for postoperative recovery in older patients(≥65 age).However,evidence for this is lacking.AIM To evaluate the effect of anesthesia on postoperative complications in older patients undergoing hip surgery.METHODS This is a retrospective,propensity score-matched,cohort study.Patients≥65-years-old who underwent hip surgery at the Traditional Chinese Medicine of Guangdong Provincial Hospital in China from October 2016 to June 2020 were included.The operative methods were femoral fracture’s internal fixation and hip replacement.The orthopedic doctors in different hospitals of our group have varied requirements for patients’out-of-bed time after surgery.Therefore,spinal anesthesia or general anesthesia was selected according to the requirements of the orthopedic doctors.The primary outcome of this study was complications during the hospitalization of the postoperative patient.The length of hospital stay,postoperative blood transfusion,routine blood analysis,renal function,coagulation function,and inflammatory correlations were secondary outcomes.Propensity score matching(PSM)was performed utilizing logistic regression.RESULTS Among the 864 patients identified from the electronic medical record data database,we screened out those with incomplete medical record data.After PSM of the baseline values of the two groups of patients,data of 309 patients(206 patients in spinal anesthesia group and 103 patients in general anesthesia)were utilized in this study.67/309 patients had complications,including postoperative limb dysfunction,pulmonary infection,delirium,lower extremity venous thrombosis,and shock.The incidence of complications was not related to anesthesia methods(P>0.05),but the levels of D-Dimer(P=0.017),fibrinogen(P=0.005),and high-sensitivity C-reactive protein(hs CRP)(P=0.002)in the spinal anesthesia group were significantly higher than those in the general anesthesia group.CONCLUSION Anesthesia technology is not a risk factor for postoperative complications of hip surgery.The levels of D-Dimer and hs CRP were higher in the spinal anesthesia group.展开更多
AIM:To quantitatively examine the impacts of an easyto-measure parameter-weight gain-on metabolic syndrome development among middle-aged adults. METHODS:We conducted a five-year interval observational study.A total of...AIM:To quantitatively examine the impacts of an easyto-measure parameter-weight gain-on metabolic syndrome development among middle-aged adults. METHODS:We conducted a five-year interval observational study.A total of 1384 middle-aged adults not meeting metabolic syndrome(MetS)criteria at the initial screening were included in our analysis.Baseline data such as MetS-components and lifestyle factors were collected in 2002.Body weight and MetS-components were measured in both 2002 and 2007.Participants were classified according to proximal quartiles of weight gain(WG)in percentages(%WG≤1%,1%< %WG≤5%,5%<%WG≤10%and%WG>10%, defined as:control,mild-WG,moderate-WG and severe-WG groups,respectively)at the end of the follow-up. Multivariate models were used to assess the association between MetS outcome and excessive WG in the total population,as well as in both genders. RESULTS:In total,175(12.6%)participants fulfilled MetS criteria within five years.In comparison to the control group,mild-WG adults had an insignificant risk for MetS development while adults having moderate-WG had a 3.0-fold increased risk for progression to MetS [95%confidence interval(CI),1.8-5.1],and this risk was increased 5.4-fold(95%CI,3.0-9.7)in subjects having severe-WG.For females having moderate-and severe-WG,the risk for developing MetS was 3.6(95% CI,1.03-12.4)and 5.5(95%CI,1.4-21.4),respectively. For males having moderate-and severe-WG,the odds ratio for MetS outcome was respectively 3.0(95%CI, 1.6-5.5)and 5.2(95%CI,2.6-10.2). CONCLUSION:For early-middle-aged healthy adults with a five-year weight gain over 5%,the severity of weight gain is related to the risk for developing metabolic syndrome.展开更多
ackground:The gradual ageing of the population,and its effect on public spending,constitutes an urgent challenge for advanced economies.Through this study,we analyse the effect of older people,and their health and ind...ackground:The gradual ageing of the population,and its effect on public spending,constitutes an urgent challenge for advanced economies.Through this study,we analyse the effect of older people,and their health and individual characteristics,on public health spending.Methods:Using logistic regression methods,we have analysed the use of different health services and health technologies by older people in Spain,controlled for several health,socioeconomic,and other individual factors.Results:The main factors that explain the consumption of both health services and health technology,above age,are related to the so-called need factors:self-reported health status,presence of chronic diseases,and disability.Conclusion:Knowing the main factors that imply greater public health spending is a topic of special interest for designing efficient health policies,in a context of growth in public health spending.In this way,preventive attention on the so-called need factors may be an important driver to improve the effectiveness of spending.展开更多
Background Heart failure(HF)is a leading cause of hospitalization and mortality for older chronic kidney disease(CKD)patients.However,the epidemiological data is scarce.We aimed to determine the prevalence of left ven...Background Heart failure(HF)is a leading cause of hospitalization and mortality for older chronic kidney disease(CKD)patients.However,the epidemiological data is scarce.We aimed to determine the prevalence of left ventricular(LV)dysfunction and HF,and to explore the risk factors for HF among those patients.Methods This is a cross-sectional analysis of the China Hypertension Survey conducted between October 2012 and December 2015.A total of 5,808 participants aged≥65 years were included in the analysis.Self-reported history of HF and any other cardiovascular diseases was acquired.2-D and Doppler echocardiography were used to assess LV dysfunction.CKD was defined as either estimated glomerular filtration rate(eGFR)<60 mL/min per 1.73 m2 or urinary albumin to creatinine ratio(ACR)≥30 mg/g.Results Among CKD patients aged≥65 years,the weighted prevalence of HF,heart failure with preserved ejection fraction(HFpEF),heart failure with mid-range ejection fraction(HFmrEF),and heart failure with reduced ejection fraction(HFrEF)was 4.8%,2.5%,0.8%,and 1.7%,respectively.The weighted prevalence of HF was 5.0%in patients with eGFR<60 mL/min per 1.73 m2,and was 5.9%in patients with ACR≥30 mg/g.The prevalence of LV systolic dysfunction was 3.1%,and while it was 8.9%for moderate/severe diastolic dysfunction.Multivariate analysis showed that smoking was significantly associated with the risk of HF.Furthermore,age,smoking,and residents in rural areas were significantly associated with a risk of LV diastolic dysfunction.Conclusions The prevalence of HF and LV dysfunction was high in older patients with CKD,suggesting that particular strategies will be required.展开更多
This paper aims to investigate how social contacts affect middle-aged and older adults’(MOA)mental health,happiness,depression,and loneliness in China.The results show that social relations lead to an improvement of ...This paper aims to investigate how social contacts affect middle-aged and older adults’(MOA)mental health,happiness,depression,and loneliness in China.The results show that social relations lead to an improvement of mental health and hap-piness and relief of depression and loneliness.For respondents who changed the sta-tus of their social contacts during the sample period,social relations benefit overall mental health and happiness but have no significant impact on depression and lone-liness.Moreover,the loss in mental health and happiness from quitting the social activities exceeds the gain from joining.This asymmetrical impact between adding and dropping social contacts emphasizes the importance of maintaining the social relations of current participants.On average,the MOA’s willingness to pay(WTP)for social contacts ranges from$235 to$270,or 9.57-11.00%of income a year.展开更多
Accumulating evidence in recent years has reinforced the notion that non-alcoholic fatty liver disease/metabolic dysfunction-associated fatty liver disease/metabolic dysfunction steatotic liver disease(NAFLD/MAFLD/MAS...Accumulating evidence in recent years has reinforced the notion that non-alcoholic fatty liver disease/metabolic dysfunction-associated fatty liver disease/metabolic dysfunction steatotic liver disease(NAFLD/MAFLD/MASLD)is a multisystem disease that increases the risk of all-cause and disease-specific mortality(1,2).展开更多
检索中、西文大型权威数据库(包括CNKI、PubMed、Elsevier and PsycInfo)中有关中国老年人口的痴呆研究文献13037篇,对这些文献的分析结果表明:1.研究主题涉及痴呆的流行病学(1.68%)、痴呆的发病机制与风险因素(37.4%)、痴呆的临床表现...检索中、西文大型权威数据库(包括CNKI、PubMed、Elsevier and PsycInfo)中有关中国老年人口的痴呆研究文献13037篇,对这些文献的分析结果表明:1.研究主题涉及痴呆的流行病学(1.68%)、痴呆的发病机制与风险因素(37.4%)、痴呆的临床表现与诊断(9.8%)、痴呆的治疗与干预(40.2%)以及关于痴呆的其它研究(10.9%);2.不同研究所报道的我国痴呆患病率彼此差异很大,60岁及以上人口的痴呆患病率平均为3.5%(95%CI 2.8-4.2),且患病率随年龄而增长;3.痴呆的发病机制非常复杂,是由内外多种因素交互作用的结果,其中,有些风险因素的结果比较一致,有些保护因素的结果也有共识,但不少因素的影响尚需进一步探讨;4.研究认为,今后需要增强样本代表性、完善检测与诊断工具、在加强痴呆流行病学和临床症状研究的同时,进一步加强痴呆患病的延缓因素研究,以便为老年痴呆的护理和干预提供客观的科学依据。展开更多
文摘A buttress on the need for welfare program in Nigeria and the important obligation to consider the Economics’and CIA’s contextual position for the dependency ratios,both total and elderly dependency ratio alongside the consideration of the age structure and demography statistics of Nigeria relatively to other economies,particularly as an elixir for the declining older population in Nigeria and the aged male contraction in the nation.Although,older female population is higher in every country as obtainable globally,the Nigerian case is that of drastic contraction in both aged male and older population generally.Therefore,the submission is that the government has to consider the total dependency ratio to the elderly dependency ratio,which is all-encompassing in order to cater for the declining older population and to appropriate the requisite welfare cum benefits programs in the nation.
基金Supported by grants from the National Institute on Aging (Nos. AG034956, AG045094)
文摘1.Introduction With the increase in older populations worldwide1 comes an increased health burden related to chronic diseases.2–4One of the most disabling of these is knee osteoarthritis(OA),which occurs in millions of older adults who subsequently live with joint pain and stiffness,leading to chronic disability and a diminished quality of life.5,6 Epidemiological evidence shows a higher prevalence of OA in older adults living in urban and
文摘BACKGROUND Spinal anesthesia is superior to general anesthesia for postoperative recovery in older patients(≥65 age).However,evidence for this is lacking.AIM To evaluate the effect of anesthesia on postoperative complications in older patients undergoing hip surgery.METHODS This is a retrospective,propensity score-matched,cohort study.Patients≥65-years-old who underwent hip surgery at the Traditional Chinese Medicine of Guangdong Provincial Hospital in China from October 2016 to June 2020 were included.The operative methods were femoral fracture’s internal fixation and hip replacement.The orthopedic doctors in different hospitals of our group have varied requirements for patients’out-of-bed time after surgery.Therefore,spinal anesthesia or general anesthesia was selected according to the requirements of the orthopedic doctors.The primary outcome of this study was complications during the hospitalization of the postoperative patient.The length of hospital stay,postoperative blood transfusion,routine blood analysis,renal function,coagulation function,and inflammatory correlations were secondary outcomes.Propensity score matching(PSM)was performed utilizing logistic regression.RESULTS Among the 864 patients identified from the electronic medical record data database,we screened out those with incomplete medical record data.After PSM of the baseline values of the two groups of patients,data of 309 patients(206 patients in spinal anesthesia group and 103 patients in general anesthesia)were utilized in this study.67/309 patients had complications,including postoperative limb dysfunction,pulmonary infection,delirium,lower extremity venous thrombosis,and shock.The incidence of complications was not related to anesthesia methods(P>0.05),but the levels of D-Dimer(P=0.017),fibrinogen(P=0.005),and high-sensitivity C-reactive protein(hs CRP)(P=0.002)in the spinal anesthesia group were significantly higher than those in the general anesthesia group.CONCLUSION Anesthesia technology is not a risk factor for postoperative complications of hip surgery.The levels of D-Dimer and hs CRP were higher in the spinal anesthesia group.
文摘AIM:To quantitatively examine the impacts of an easyto-measure parameter-weight gain-on metabolic syndrome development among middle-aged adults. METHODS:We conducted a five-year interval observational study.A total of 1384 middle-aged adults not meeting metabolic syndrome(MetS)criteria at the initial screening were included in our analysis.Baseline data such as MetS-components and lifestyle factors were collected in 2002.Body weight and MetS-components were measured in both 2002 and 2007.Participants were classified according to proximal quartiles of weight gain(WG)in percentages(%WG≤1%,1%< %WG≤5%,5%<%WG≤10%and%WG>10%, defined as:control,mild-WG,moderate-WG and severe-WG groups,respectively)at the end of the follow-up. Multivariate models were used to assess the association between MetS outcome and excessive WG in the total population,as well as in both genders. RESULTS:In total,175(12.6%)participants fulfilled MetS criteria within five years.In comparison to the control group,mild-WG adults had an insignificant risk for MetS development while adults having moderate-WG had a 3.0-fold increased risk for progression to MetS [95%confidence interval(CI),1.8-5.1],and this risk was increased 5.4-fold(95%CI,3.0-9.7)in subjects having severe-WG.For females having moderate-and severe-WG,the risk for developing MetS was 3.6(95% CI,1.03-12.4)and 5.5(95%CI,1.4-21.4),respectively. For males having moderate-and severe-WG,the odds ratio for MetS outcome was respectively 3.0(95%CI, 1.6-5.5)and 5.2(95%CI,2.6-10.2). CONCLUSION:For early-middle-aged healthy adults with a five-year weight gain over 5%,the severity of weight gain is related to the risk for developing metabolic syndrome.
文摘ackground:The gradual ageing of the population,and its effect on public spending,constitutes an urgent challenge for advanced economies.Through this study,we analyse the effect of older people,and their health and individual characteristics,on public health spending.Methods:Using logistic regression methods,we have analysed the use of different health services and health technologies by older people in Spain,controlled for several health,socioeconomic,and other individual factors.Results:The main factors that explain the consumption of both health services and health technology,above age,are related to the so-called need factors:self-reported health status,presence of chronic diseases,and disability.Conclusion:Knowing the main factors that imply greater public health spending is a topic of special interest for designing efficient health policies,in a context of growth in public health spending.In this way,preventive attention on the so-called need factors may be an important driver to improve the effectiveness of spending.
基金the China National Science&Technology Pillar Program(2011BAI11B01)the National Health and Family Planning Commission,China(No.201402002)the CAMS Innovation Fund for Medical Sciences(2017-I2M-1-004)。
文摘Background Heart failure(HF)is a leading cause of hospitalization and mortality for older chronic kidney disease(CKD)patients.However,the epidemiological data is scarce.We aimed to determine the prevalence of left ventricular(LV)dysfunction and HF,and to explore the risk factors for HF among those patients.Methods This is a cross-sectional analysis of the China Hypertension Survey conducted between October 2012 and December 2015.A total of 5,808 participants aged≥65 years were included in the analysis.Self-reported history of HF and any other cardiovascular diseases was acquired.2-D and Doppler echocardiography were used to assess LV dysfunction.CKD was defined as either estimated glomerular filtration rate(eGFR)<60 mL/min per 1.73 m2 or urinary albumin to creatinine ratio(ACR)≥30 mg/g.Results Among CKD patients aged≥65 years,the weighted prevalence of HF,heart failure with preserved ejection fraction(HFpEF),heart failure with mid-range ejection fraction(HFmrEF),and heart failure with reduced ejection fraction(HFrEF)was 4.8%,2.5%,0.8%,and 1.7%,respectively.The weighted prevalence of HF was 5.0%in patients with eGFR<60 mL/min per 1.73 m2,and was 5.9%in patients with ACR≥30 mg/g.The prevalence of LV systolic dysfunction was 3.1%,and while it was 8.9%for moderate/severe diastolic dysfunction.Multivariate analysis showed that smoking was significantly associated with the risk of HF.Furthermore,age,smoking,and residents in rural areas were significantly associated with a risk of LV diastolic dysfunction.Conclusions The prevalence of HF and LV dysfunction was high in older patients with CKD,suggesting that particular strategies will be required.
文摘This paper aims to investigate how social contacts affect middle-aged and older adults’(MOA)mental health,happiness,depression,and loneliness in China.The results show that social relations lead to an improvement of mental health and hap-piness and relief of depression and loneliness.For respondents who changed the sta-tus of their social contacts during the sample period,social relations benefit overall mental health and happiness but have no significant impact on depression and lone-liness.Moreover,the loss in mental health and happiness from quitting the social activities exceeds the gain from joining.This asymmetrical impact between adding and dropping social contacts emphasizes the importance of maintaining the social relations of current participants.On average,the MOA’s willingness to pay(WTP)for social contacts ranges from$235 to$270,or 9.57-11.00%of income a year.
基金supported in part by the Southampton NIHR Biomedical Research Centre,UK (NIHR 203319).
文摘Accumulating evidence in recent years has reinforced the notion that non-alcoholic fatty liver disease/metabolic dysfunction-associated fatty liver disease/metabolic dysfunction steatotic liver disease(NAFLD/MAFLD/MASLD)is a multisystem disease that increases the risk of all-cause and disease-specific mortality(1,2).
文摘检索中、西文大型权威数据库(包括CNKI、PubMed、Elsevier and PsycInfo)中有关中国老年人口的痴呆研究文献13037篇,对这些文献的分析结果表明:1.研究主题涉及痴呆的流行病学(1.68%)、痴呆的发病机制与风险因素(37.4%)、痴呆的临床表现与诊断(9.8%)、痴呆的治疗与干预(40.2%)以及关于痴呆的其它研究(10.9%);2.不同研究所报道的我国痴呆患病率彼此差异很大,60岁及以上人口的痴呆患病率平均为3.5%(95%CI 2.8-4.2),且患病率随年龄而增长;3.痴呆的发病机制非常复杂,是由内外多种因素交互作用的结果,其中,有些风险因素的结果比较一致,有些保护因素的结果也有共识,但不少因素的影响尚需进一步探讨;4.研究认为,今后需要增强样本代表性、完善检测与诊断工具、在加强痴呆流行病学和临床症状研究的同时,进一步加强痴呆患病的延缓因素研究,以便为老年痴呆的护理和干预提供客观的科学依据。