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突发性聋患者中枢敏化因素分析及临床干预
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作者 陈元星 甄全胜 +3 位作者 孙悍军 张清华 杨萌 孙勍 《中国耳鼻咽喉头颈外科》 CSCD 2024年第1期57-59,共3页
目的探讨突发性聋的可能机制,以及中枢敏化因素临床干预在突发性聋患者中的应用分析。方法选取2020年1月~2023年1月在解放军总医院第三医学中心耳鼻咽喉头颈外科住院治疗且合并偏头痛或其他中枢敏化因素的37例突发性聋患者作为治疗组,... 目的探讨突发性聋的可能机制,以及中枢敏化因素临床干预在突发性聋患者中的应用分析。方法选取2020年1月~2023年1月在解放军总医院第三医学中心耳鼻咽喉头颈外科住院治疗且合并偏头痛或其他中枢敏化因素的37例突发性聋患者作为治疗组,随机选取同期无偏头痛及其他中枢敏化因素的30例突发性聋患者作为对照组。两组患者均参照突发性聋指南进行规范化分型治疗,对合并偏头痛或其他中枢敏化因素的患者进行抗偏头痛治疗,比较两组的治疗效果。结果治疗组总有效率为81.1%(30/37),其中痊愈13例、显效10例、有效7例、无效7例;对照组总有效率66.7%(20/30),其中痊愈6例、显效6例、有效8例、无效10例。治疗组痊愈及显效比例高于对照组,两组总有效率差异无统计学意义(χ^(2)=1.1364,P>0.05)。结论偏头痛是中枢敏化的一种表现形式,中枢敏化可能参与到一部分突发性聋患者的发病机制中,对突发性聋患者进行中枢敏化评估,合并偏头痛或其他中枢敏化因素的突发性聋患者可以考虑配合抗偏头痛药物进行治疗,有可能改善患者预后。 展开更多
关键词 偏头痛(migraine disorders) 治疗结果(Treatment Outcome) 突发性聋(sudden deafness) 中枢敏化(central sensitization)
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100 CASES OF INTRACTABLE MIGRAINE TREATED BY ACUPUNCTURE AND CUPPING 被引量:2
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作者 多秀瀛 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 1999年第3期205-206,共2页
The author has treated 100 cases ofintractable migraine by acupuncture andcupping with satisfactory therapeutic results,as reported as follows.Clinical Data There were 100 cases in this series,including 38 males and 6... The author has treated 100 cases ofintractable migraine by acupuncture andcupping with satisfactory therapeutic results,as reported as follows.Clinical Data There were 100 cases in this series,including 38 males and 62 females. 8 展开更多
关键词 Acupuncture Therapy ADOLESCENT ADULT Female Humans Male Middle Aged migraine disorders
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Treatment of Migraine with Acupuncture at Points Pertaining to the Liver and Gallbladder Channels
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作者 李炜 邓干初 +6 位作者 刘远珍 刘卫平 钟广伟 王素娥 文玲波 李学文 毛树章 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2003年第3期205-206,共2页
In studying the syndrome of yang-hyperactivity, we found that most migraine patients were with hyperactivity of the liver-yang, stagnation of the liver-qiand blood stasis, and stagnation of the liverqi and deficiency ... In studying the syndrome of yang-hyperactivity, we found that most migraine patients were with hyperactivity of the liver-yang, stagnation of the liver-qiand blood stasis, and stagnation of the liverqi and deficiency of the spleen. To evaluate the needling effects on migraine and to approach its mechanism, we have launched a study in 207 cases since 1997. The results were satisfactory and reported as follows. 展开更多
关键词 ELECTROACUPUNCTURE Acupuncture Points ADOLESCENT ADULT Aged Calcitonin Gene-Related Peptide Diagnosis Differential Female Follow-Up Studies Humans Male Medicine Chinese Traditional MERIDIANS Middle Aged migraine disorders Substance P
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Clinical Records for Acupuncture Treatment of Migraine
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作者 陶莎 毛树章 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2005年第1期54-57, ,共4页
Migraine, characterized by periodic attacks that hampers the quality of the daily life, is an obstinate symptom complex commonly seen in the clinic. In contrast with the poor effects obtained in Western medicine, acup... Migraine, characterized by periodic attacks that hampers the quality of the daily life, is an obstinate symptom complex commonly seen in the clinic. In contrast with the poor effects obtained in Western medicine, acupuncture is a safe and effective treatment for migraine. The following are the clinical records for acupuncture treatment of migraine in the recent 5 years. 展开更多
关键词 Acupuncture Points Acupuncture Therapy Humans migraine disorders
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ACUPUNCTURE TREATMENT OF MIGRAINE IN GERMANY 被引量:1
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作者 胡金生 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 1998年第2期99-101,共3页
1. The fact that 25% of the German population have the problem of headache, or migraine is uniquely characteristic of Germany. The administration of analgesics which used to be their local treatment for the problem ca... 1. The fact that 25% of the German population have the problem of headache, or migraine is uniquely characteristic of Germany. The administration of analgesics which used to be their local treatment for the problem can neither give a radical cure nor avoid certain side effects. 2. It can be seen from the therapeutic result of a 80% effective rate in 89 cases of migraine that acupuncture treatment is an effective therapy for 'German migraine' without any side effects. 3. Since 10% of the migraine cases were related to the improper sleeping posture, due attention should be paid and appropriate measures be taken to prevent occurrence of headache. 4. While receiving acupuncture treatment, the cases of migraine related to menstruation should also try to regulate their emmeniopathy. 5. It seems somewhat difficult for acupuncture treatment to give good effects in those with migraine related to psychological pressures and in those given long-term administration of contraceptives. This needs to be further studied. 展开更多
关键词 Acupuncture Analgesia Acupuncture Points ADOLESCENT ADULT Aged Aged 80 and over CHILD Diagnosis Differential FEMALE Humans Male Medicine Chinese Traditional Middle Aged migraine disorders
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Examples of Clinical Application of Fengchi 被引量:1
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作者 陈跃来 张天嵩 +1 位作者 郑魁山 余敏 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2002年第2期128-131,共4页
Fengchi (GB 20) is a point of the Gallbladder Channel of Foot-Shaoyang. Just as its name implies that it is a place where the pathogenic wind converges. So, the point is regarded as an important point to dispel wind s... Fengchi (GB 20) is a point of the Gallbladder Channel of Foot-Shaoyang. Just as its name implies that it is a place where the pathogenic wind converges. So, the point is regarded as an important point to dispel wind since it has the functions of clearing heat and brightening the eye, dispelling wind and inducing resuscitation. 展开更多
关键词 Acupuncture Points Acupuncture Therapy ADULT BLEPHAROPTOSIS Common Cold FEMALE Humans Male Middle Aged migraine disorders
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Clinical Application of the Point Xuanzhong
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作者 胡燕芬 王新中 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2003年第4期275-277,共3页
Xuanzhong (GB 39), also called Juegu, belongs tothe Gallbladder Channel of Foot Shaoyang, and it isan Influential Point of the marrow.
关键词 Acupuncture Points Acupuncture Therapy ADULT FEMALE HEMIPLEGIA Humans Male Middle Aged migraine disorders PERIARTHRITIS Shoulder Joint
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Clinical Application of Point Sanyinjiao
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作者 杨静 王新中 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2001年第4期291-293,共3页
Point Sanyinjiao (SP 6) gets its name due to its location. It is located 3 cun directly above the tip of the medial malleolus, on the posterior border of the medial aspect of the tibia, where the three yin channels of... Point Sanyinjiao (SP 6) gets its name due to its location. It is located 3 cun directly above the tip of the medial malleolus, on the posterior border of the medial aspect of the tibia, where the three yin channels of the liver, spleen, and kidney meet. 展开更多
关键词 Acupuncture Therapy ADULT FEMALE Foot Injuries Humans MALE Middle Aged migraine disorders Urinary Retention
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Effect of Qilongtoutong granule on calcitonin gene-related peptide,beta-endorphin, serotonin, dopamine, and noradrenalin in migraine model rats and mice 被引量:9
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作者 Xiaofang Wu Meikui Zhang Huai Huang 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2014年第2期188-193,共6页
OBJECTIVE: To study the effect of Qilongtoutong granule (QLTT) on plasma calcitonin gene-related peptide (CGRP), beta-endorphin (I[3-EP), 5-HT, dopa- mine (DA), noradrenalin (NE), and blood viscosity in mig... OBJECTIVE: To study the effect of Qilongtoutong granule (QLTT) on plasma calcitonin gene-related peptide (CGRP), beta-endorphin (I[3-EP), 5-HT, dopa- mine (DA), noradrenalin (NE), and blood viscosity in migraine model rats and mice. METHODS: Both the acute blood stasis model group and nitroglycerin-induced migraine model group included 60 Sprague-Dawley rats. The reser- pine-reduced model group had 60 Kunming mice. Rats from each test were grouped into normal con- trol group, model group, Zhengtian pill (ZTP) group, and high, moderate, or low-dose QLTT groups. In the acute blood stasis model test, after gavage for 7 days, rats were given 0.8 mL/kg adren- aline hydrochloride subcutaneously twice, and kept in ice water for 5 min. After fasting for 12 h, rats were anesthetized and blood samples were collected for detection of blood viscosity. In the nitro- glycerin-induced migraine group, after gavage for 7 days, rats were intraperitoneally injected nitro- glycerin (10 mg/kg), and 4 h later, blood samples were collected from postcava for measuring the plasma CGRP and 13-EP levels. In the reserpine-re- duced model test, except the normal control group, mice were administered reserpine (0.25 mg/ kg, i.h.) for 9 days. Mice received intragastric admin- istration from the third day to the ninth day. One hour after the last gavage, blood and brain tissue samples were obtained. Then, blood clotting time and the contents of neurotransmitters were deter- mined. RESULTS: QLTT- (3.6, 1.8, and 0.9 g/kg) and ZTP-treated rats had lower blood viscosity than that in model rats under different shear rates (P〈 0.01). QLTT- (3.6, 1.8 g/kg) and ZTP-treated rats had significantly lower plasma CGRP levels and higher plasma 13-EP levels than those in model rats (P〈 0.01). QLTT treatment at dose of 0.9 g/kg had lower plasma CGRP levels as well (P〈0.05). QLTT- (5.2, 2.6 g/kg) and ZTP-treated mice had longer blood clotting time than that in model mice (P〈0.01). QLTT- (2.6 g/kg) and ZTP-treated mice had higher plasma serotonin (5-HT) levels than those in model mice (P〈0.05). CONCLUSION: QLTT-treated animals had lower plasma CGRP level, higher plasma 13-EP, 5-HT, high- er brain tissue 5-HT, NE, DA levels, and lower blood viscosity than those in the migraine model animals. 展开更多
关键词 migraine disorders Calcitonin gene-related peptide BETA-ENDORPHIN Medicine Chinesetraditional Qilongtoutong granule
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Clinical observation on acupuncture at points of Shaoyang meridians plus moving cupping on the neck and shoulder for migraine 被引量:5
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作者 李芳玲 贲定严 吴江昀 《Journal of Acupuncture and Tuina Science》 CSCD 2017年第5期377-381,共5页
Objective: To observe the efficacy of acupuncture at points of Shaoyang meridians plus moving cupping on neck and shoulder for migraine. Methods: A total of 64 migraine cases were randomly allocated into an observat... Objective: To observe the efficacy of acupuncture at points of Shaoyang meridians plus moving cupping on neck and shoulder for migraine. Methods: A total of 64 migraine cases were randomly allocated into an observation group and a control group, 32 cases in each group. Random number table method was used in allocation. Acupuncture at points of Shaoyang meridians and cupping on neck and shoulder were used for cases in the observation group, which contain acupuncture 5 times a week and cupping once a week. Oral flunarizine hydrochloride capsules were used for cases in the control group, 10 mg for each dose, 1 dose a day. 2 weeks constitutes a course of treatment. The patients were treated for two courses of treatment in both groups. After that, the changes of visual analogue scale (VAS) and the migraine disability assessment questionnaire (MIDAS) were observed, as well as the clinical efficacy. Results: The total effective rate and recovery and marked effective rate in the observation group were 93.8% and 71.0% respectively, versus 78.1% and 43.8% in the control group, showing statistical significant differences (both P〈O.05). There were significant decreases in VAS and MIDAS scores after treatments in both groups (both P〈O.05). VAS and MIDAS scores in the observation group were significantly different from those in the control group (both P〈0.05). Conclusion: Combining acupuncture at points of Shaoyang meridians and cupping on neck and shoulder can relieve headache and reduce influence of migraine on life. It can produce a better efficacy than oral flunarizine hydrochloride capsules in treating migraine patients. 展开更多
关键词 Acupuncture Therapy Cupping Therapy Moving Cupping Therapy migraine disorders Shaoyang Meridians Visual Analogue scale Pain Measurement
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Cerebral fractional amplitude of low-frequency fluctuations may predict headache intensity improvement following acupuncture treatment in migraine patients 被引量:5
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作者 Li Zhengjie Zhou Jun +9 位作者 Cheng Shirui Lan Lei Sun Ruirui Liu Mailan Yang Jie Gao Yujie Guo Taipin Gong Qiyong Zeng Fang Liang Fanrong 《Journal of Traditional Chinese Medicine》 SCIE CSCD 2020年第6期1041-1051,共11页
OBJECTIVE:To explore how baseline resting-state cerebral function predicts clinical outcomes of acupuncture treatment for migraine.METHODS:One hundred migraine patients and 46 healthy subjects were recruited.Patients ... OBJECTIVE:To explore how baseline resting-state cerebral function predicts clinical outcomes of acupuncture treatment for migraine.METHODS:One hundred migraine patients and 46 healthy subjects were recruited.Patients were randomized into the acupuncture,sham acupuncture,and waiting list groups.Resting-state functional magnetic resonance imaging data were collected at baseline and after 1 month of longitudinal acupuncture treatments.Fractional amplitude of low-frequency fluctuations(f ALFF)calculations were applied to explore the associations between baseline f ALFF and changes in clinical variables in the acupuncture treatment group and the waiting list group.RESULTS:Compared with healthy subjects,migraine patients had lower f ALFF in the left rostral ventromedial medulla,right thalamus,left amygdala,and right angular gyrus.Regression analyses revealed that baseline f ALFF values in the left middle frontal gyrus,left superior temporal gyrus,and middle temporal gyrus were positively associated with headache intensity changes in the acupuncture treatment group,while baseline f ALFF values in the bilateral lingual gyrus and cuneus were negatively associated with headache intensity changes in this group.CONCLUSION:The baseline f ALFF values of brain regions associated with cognitive pain modulation,but not migraine severity,may predict future headache intensity improvement levels in migraine patients receiving acupuncture treatment. 展开更多
关键词 Acupuncture migraine disorders Treatment outcome Magnetic resonance imaging
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Effect of acupuncture at Fengchi(GB 20)on the activity of myosin light chain kinase in the middle meningeal artery of migraine modeled rats 被引量:6
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作者 Zhou Peijuan Wang Aicheng +2 位作者 Li Bai Liu Chunyan Wang Yu 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2015年第3期301-305,共5页
OBJECTIVE:To study the effect of acupuncture at Fengchi(GB 20) on the activation of myosin light chain kinase(MLCK) in the middle meningeal artery of migraine modeled rats.METHODS:Forty-four clean grade healthy female... OBJECTIVE:To study the effect of acupuncture at Fengchi(GB 20) on the activation of myosin light chain kinase(MLCK) in the middle meningeal artery of migraine modeled rats.METHODS:Forty-four clean grade healthy female Sprague-Dawley(SD) rats were randomly divided into four groups:the control group,blank control group,Fengchi(GB 20) acupuncture group,and Fengchi(GB 20) prevention group.Neurogenic inflammation of these rats was induced by electrical stimulation.The γ-^(32)P infiltration method was then used to detect MLCK activation in the middle meningeal artery,and immunocytochemistry was applied to detect the structural protein expression of MLCK.RESULTS:The migraine model was successfully established in the rats.Compared with the control group,MLCK activation was significantly decreased in the blank control group(P < 0.01).CONCLUSION:The activation of MLCK in the middle meningeal artery was increased by acupuncture at Fengchi(GB 20),indicating its effectiveness in preventing and curing on acute migraine attacks. 展开更多
关键词 Myosin-light-chain kinase Point GB 20(Fengchi) migraine disorders Middle meningeal artery
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Effect of Tianshu capsule in treatment of migraine:a meta-analysi of randomized control trials 被引量:2
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作者 Wei Xia Mingjin Zhu +4 位作者 Zhe Zhang Deizhao Kong Wei Xiao Lianqun Jia Guanlin Yang 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2013年第1期9-14,共6页
OBJECTIVE: To review the efficacy of Tianshu capsule in the treatment of migraine. METHODS: Retrieving papers from Pubmed, cochrane central register of controlled trials (CENTRAL), Weipu database (VIP), China bi... OBJECTIVE: To review the efficacy of Tianshu capsule in the treatment of migraine. METHODS: Retrieving papers from Pubmed, cochrane central register of controlled trials (CENTRAL), Weipu database (VIP), China biology medicine (CBM), China national knowledge infrastructure (CNKI), and Wanfang Data. Two reviewers retrieved and extracted the information indepen- dently. Retrieval time scale is up to August 2012.Software Review Manager 5.1 was used for analysis RESULTS: A total of 10 studies including 937 mi- graine patients. The merged data shows Tianshu capsule had a higher effective rate in treating mi- graine, and there is no significant heterogeneity between Tianshu capsule group and control group (x2=6.33, dr-=9, P=0.71, F=0%), OR=4.18 [95%0 (2.93,5.95)]. Tianshu capsule alone compared to conventional therapy also showed advantages, and there was low heterogeneity (X2=4.53, dr=3, P=0.21, 12 = 34%), OR=3.95 [95% CI (2.32, 6.72)]. Meta-analysis results show that clinical efficacy of Tianshu capsule was better than that of the control group in the treatment of migraine and there was a signifi- cant difference (P〈0.000 01). CONCLUSION: Tianshu capsule had better efficacy in the treatment of migraine with fewer adverse effects. 展开更多
关键词 migraine disorders META-ANALYSIS Ran-domized controlled trial Tianshu capsule
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Therapeutic Effect Observation on Combining Electroacupuncture and Tuina for Migraine 被引量:2
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作者 Guo Qing Hua Yu +3 位作者 Wang Hai-qin Li Ying Ji Quan Han Chou-ping 《Journal of Acupuncture and Tuina Science》 2014年第3期174-179,共6页
Objective: To observe the clinical effect of combining electroacupuncture and local tuina for migraine. Methods: A total of 94 migraine cases were randomly allocated into an observation group and a medication group, 4... Objective: To observe the clinical effect of combining electroacupuncture and local tuina for migraine. Methods: A total of 94 migraine cases were randomly allocated into an observation group and a medication group, 48 cases in each group. Electroacupuncture and local tuina were used for cases in the observation group, whereas oral Flunarizine Hydrochloride capsules were used for cases in the medication group. Then the frequency of attacks, severity of the pain, duration of the headache, and associated symptoms of headache before and after treatment in the two groups were observed and compared. Results: The total effective rate in the observation group was 93.8%, versus 63.0% in the medication group, showing a statistical significant difference(P < 0.05). There were statistical significant differences in frequency of attacks, severity of the pain, duration of the headache and associated symptoms between the two groups(P<0.05). In addition, there were statistical significant differences in relapse rates after 4 and 8 weeks of treatment(P<0.05). Conclusion: Combining electroacupuncture and local tuina can obtain better effect and lower relapse rate than oral Flunarizine Hydrochloride capsules in migraine patients. 展开更多
关键词 Acupuncture Therapy ELECTROACUPUNCTURE TUINA MASSAGE migraine disorders HEADACHE
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Effects of feet reflexology versus segmental massage in reducing pain and its intensity,frequency and duration of the attacks in females with migraine:a pilot study 被引量:1
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作者 Wojciech Kobza Pawel Lizis Halina Romualda Zieba 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2017年第2期214-219,共6页
OBJECTIVE:To evaluate the effects of feet reflexology versus segmental massage in reducing pain and its intensity, frequency and duration of the attacks in females suffering from migraine.METHODS:Forty eight females a... OBJECTIVE:To evaluate the effects of feet reflexology versus segmental massage in reducing pain and its intensity, frequency and duration of the attacks in females suffering from migraine.METHODS:Forty eight females aged 33-58, suffering from migraine for 2 to 10 years were included in this study from November 2013 to November2015.The study protocol was carried out in Department of Chronic Diseases at the Regional Hospital in Zywiec.In the reflexology group(RG) the patients received a series of 10 treatments 2 times per week; in the segmental massage group(SMG) the patients received a series of 15 treatments 3 times per week.Pain during migraine attacks was assessed using the visual analog scale(VAS), and headache features such as intensity(IA), frequency(FA) and duration(DA) of attacks were assessed before the treatment, just after the treatment, 3months after the treatment.RESULTS:All variables(VAS, IA, FA and DA) decreased within RG and SMG 3 months after the treatment in compare with the baseline values, and the differences were statistically significant.The differences between groups were also statistically significant.CONCLUSION:Feet reflexology and segmental massage provide a safe alternative for the pharmacological treatment of migraine.The patients with migraine obtain significant health benefits with feet reflexology. 展开更多
关键词 migraine disorders MASSAGE Visual analog scale Pilot projects
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Observation on Clinical Effects of Electroacupuncture for Migraine Without Aura 被引量:1
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作者 Fang Zhen Zhang Bi-meng 《Journal of Acupuncture and Tuina Science》 2014年第1期21-25,共5页
Objective: To observe the clinical effects of electroacupuncture(EA) for migraine without aura. Methods: The migraine patients in conformity with the conditions were randomly divided into two groups, 34 cases in each ... Objective: To observe the clinical effects of electroacupuncture(EA) for migraine without aura. Methods: The migraine patients in conformity with the conditions were randomly divided into two groups, 34 cases in each group. The treatment group was given EA and the control group was given the routine acupuncture treatment, to observe various pain indexes respectively before and one month after the treatment. Results: The general effect was remarkably better in the treatment group than that in the control group(P<0.05). Conclusion: EA is an effective therapy for migraine without aura. 展开更多
关键词 Acupuncture Therapy Electroacupuncture migraine disorders Headache
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