Research Progress on Pathogenesis and Treatment of Type 2 Diabetes Mellitus by Traditional Chinese Medicine and Western Medicine

The prevalence rate of type 2 diabetes is increasing year by year,simple surgery and Western medicine treatment has limitations,doing damage to liver and kidney function,resulting in islet function damage,insulin resistance,poor curative effect and many adverse reactions.According to the difference of patients'health conditions,traditional Chinese medicine has certain advantages in the treatment of this disease by acupuncture,auricular point treatment and prescription based on syndrome differentiation,taking replenishing qi and nourishing yin,invigorating spleen and resolving dampness as the basic principle to enhance the functions of viscera such as lung,spleen and kidney,and to strengthen the body resistance to eliminate pathogenic factors.The curative effect is remarkable and the side effect is extremely low.Therefore,this paper makes a comparative analysis of the current situation of the research on the pathogenesis and treatment of the disease between traditional Chinese medicine and Western medicine,in order to provide new ideas for clinical and scientific researchers.

Etiology and Pathogenesis of Pericarditis from the Perspective of Traditional Chinese and Western Medicine

Pericarditis is a common clinical pericardial disease with complex etiology,pathogenesis,and high recurrence rate.Interleukin-1 is an important inflammatory cytokine,which regulates the occurrence and development of inflammation by regulating IL-1α,IL-1β,and IL-IRA;it plays an important role in pericarditis.In traditional Chinese medicine,the modem understanding of its etiology and pathogenesis has been improved.In this review,the etiology and pathogenesis of pericarditis are discussed from the perspective of traditional Chinese and Western medicine.

An analysis of Liver and Kidney pathogenesis and treatment based on the theory of interpromotion and restraint of the five elements

The interpromotion and restraint of the five elements is the self-regulation mechanism of the five elements system under normal conditions.For the human viscera,by comparing the images,deducing and classifying the attributes of things,the human viscera are connected with the five elements,and it is concluded that the Liver belongs to Wood and the Kidney belongs to Water.According to the law of mutual generation and restriction between the five elements,the pathogenic causes,pathogenesis and relationship with other viscera of the Liver and Kidney can be known,so as to establish corresponding treatment methods,such as"Nourishing Water and protecting Wood"(providing Kidney for the growth of Liver method),"Golden Water symbiosis"(generation between the Lung and Kidney),"Cultivating soil and generating gold"(warming the Kidney and benefited Spleen method),Supporting lung to suppress Liver,purging heart Fire to nourish renal Water method,etc.It is of referential significance for the treatment of Liver and Kidney diseases in the diagnosis and treatment of traditional Chinese medicine.

Research progress of non-specific neck pain in traditional Chinese medicine and western medicine

Non-specific neck pain is a common disease in clinic,and its pathogenesis is not clear.With the progress of the times and the change of living and working habits,the incidence of non-specific neck pain is increasing year by year,which has a great impact on people’s physical and mental health,work and life.Traditional Chinese medicine mainly treats non-specific neck pain by acupuncture and massage,while western medicine generally uses exercise and manipulation therapy,but the quality of clinical evidence of all kinds of therapy is not high,which needs to be verified.This paper summarizes the research progress of traditional Chinese medicine and western medicine in the treatment of non-specific neck pain from the aspects of pathogenesis,etiology and pathogenesis of traditional Chinese medicine,and treatment of traditional Chinese medicine and western medicine,so as to provide reference for doctors in clinical treatment of this disease.

Treatment of Hashimoto's thyroiditis traditional Chinese and western medicine:A review

Hashimoto's Thyroiditis is a common Autoimmune disease,and clinical related research has made great progress.This article summarizes the clinical and experimental studies on Hashimoto's Thyroiditis in recent years,summarizes in five aspects from its western medicine pathogenesis(Genetics,Environment,Gender,Immunity,mi RNA),traditional Chinese medicine etiology and pathogenesis,western medicine treatment(Glucocorticoid therapy,Chemokine receptor antagonist therapy,Nutrition therapy),traditional Chinese medicine therapy(Treatment by type,Treatment by stages,Treatment by liver,Treatment by spleen and kidney,Treatment by gas,blood,phlegm and blood stasis,Prescription of experience,Characteristic theory of physician and Characteristic therapy of Traditional Chinese Medicine)and combine traditional Chinese and western medicine treatment,and puts forward the integrated treatment of traditional Chinese and western medicine is the general trend of future diagnosis and treatment of Hashimoto thyroiditis.

Rules and Characteristics of TCM Treatment Prescriptions for Patients with Decreased Ovarian Reserve

[Objectives]To analyze the characteristics and rules of traditional Chinese medicine(TCM)in the treatment of decreased ovarian reserve(DOR)in Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine.[Methods]A total of 107 patients with DOR in Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine were selected for sorting,and the usage,classification,nature,taste and meridian homing of the used drugs were statistically analyzed.[Results]A total of 107 patients were included in this stud and a total of 189 flavors of TCM are used.The total frequency of drugs was 4345 times,and a total of 535 prescriptions were issued.The top five frequency of drug use were 2261 times(50.04%)of Paeoniae Radix Alba(Cynanchum otophyllum Schneid.),2037 times(46.88%)of Corni Fructus(Cornus officinalis Sieb.et Zucc.),1818 times(41.84%)of Rehmanniae Radix Praeparata[Rehmannia glutinosa(Gaertn.)Libosch EX Fisch.et Mey.],1610 times(37.05%)of Guiban[Chinemys reevesii(Gray)],and 1303 times(29.99%)of Uncariae Ramulus Cum Uncis(Uncariar hynchophylla Miq.ex Havil.).Kidney deficiency syndrome accounted for the largest proportion at 51.40%,and the use frequency of tonic drugs accounted for the highest at 50.64%;heat-clearing drugs and qi and blood-boosting drugs separately accounted for 19.24%and 17.39%;the top 3 medicinal tastes are sweet(52.02%),pungent(20.71%)and bitter(20.32%);medicinal properties are ranked as warm(60.54%),cold(24.16%),hot(8.72%)and cool(6.49%);the main meridians are spleen,lung,liver,stomach and kidney.[Conclusions]The basic pathogenesis of DOR is deficiency of qi and blood,mainly due to dysfunction of the spleen,lung,liver,liver,stomach and other organs,and kidney deficiency and spleen deficiency are more common.

脓毒症发病机制及中西医治疗研究进展

脓毒症是一种危重病,由感染引起全身炎症反应综合征导致多器官功能障碍。目前认为,脓毒症的中西医发病机制异常复杂。中西医结合治疗脓毒症的方法也逐渐得到了研究与应用,属治疗脓毒症重要的发展方向之一。鉴于此,本文旨在对脓毒症发病机制及中西医治疗研究进展做一综述。

乳腺增生症的中西医认识及治疗研究进展

乳腺增生症(hyperplasia of mammary gland,HMG)中医病名为乳癖,是一种乳腺组织增生的疾病,其中医基本病机为情志失常,病机以肝内气机郁滞为主,兼有脾肾不足等,由此导致气滞、血瘀、痰凝。气、血、痰、瘀于乳络互结。西医病因病理尚未完全明确。西药目前尚无特异性疗法,中药治疗具有良好效果。文章将对乳癖的中西医病因病机进行论述,并结合临床案例及经验总结中医药治法治则及常用药物,以临床为角度基础,提出治疗乳癖的方法,并为乳癖病因病机的研究与探讨提供新思路。

卵巢储备功能减退的中西医病因及治疗现状

卵巢储备功能(OR)反映了女性生殖内分泌的潜能,取决于卵巢内库存卵泡的数量和质量,代表了卵巢皮质区卵泡生长、发育并形成可受精的卵母细胞的能力。很多因素会引起女性OR的下降甚至过早衰退,从而造成月经改变、闭经、不孕及流产等生殖内分泌功能紊乱表现。现代医学对卵巢储备功能减退(DOR)的病因机制阐述颇多,但临床治疗尚未统一,各种治疗方法均有一定的积极意义,但部分效果有待证实。中医从中药、针灸等方面着手,治疗优势逐渐凸显。

IgA肾病的中西医诊治进展

IgA肾病是一种原发性肾小球肾炎,容易引起肾损害,最终导致终末期肾病,使患者进入肾替代治疗阶段,给患者及其家庭带来严重的心理及经济负担。针对IgA肾病,西医逐渐研制各种靶向药物但疗效及不良反应仍需观察。文献、临床实践表明,中医药治疗IgA肾病可有效减少尿蛋白及尿红细胞,有效延缓肾功能减退,且无毒副作用。现收集大量文献,从中医对IgA肾病的病因病机认识及西医对IgA肾病的发病机制研究和治疗进行总结,让更多的青年医师借鉴学习,为更多的IgA肾病患者带来福音。

中西医协同防治慢性病的科学思路与方法

慢性病是临床上较为常见的疾病类型,具有发展隐匿、发病机制复杂、患者预后较差、临床治疗难度大等特点。中西医协同治疗对提高慢性病患者的生存质量、临床疗效有显著优势。随着社会的不断进步和人民对健康意识的不断提高,中西医协同治疗慢性病成为了当今卫生服务发展的主要方向。通过文献综述方法系统地整理了慢性病具有虚弱性、缠绵性和复杂性的发病特点,以络虚不荣、痰瘀阻络、久虚络瘀为其核心病机,同时提出了中西医协同全方位、全周期防治慢性病的科学思路与方法,旨在为慢性病防治工作提供更为全面、更科学的参考依据。

生殖器疱疹的中西医发病机制及治疗进展

生殖器疱疹(genital herpes, GH)作为临床常见的性传播疾病,根据其临床表现可归属于中医“热疮”“阴疮”等范畴,具有易复发、难根治的特点,严重影响了患者的身心健康。现代医学治疗GH主要以抗病毒、调节免疫为主,临床上取得一定成效,但都未能达到根治目的并且存在不良反应。中医药治疗GH方法多样,以辨证施治为主,具有缓解临床症状、减轻不良反应等优势。同时临床上还采用中西医结合的方法治疗GH,中西医并重取长补短,发挥各自的优势。文章就GH的中西医发病机制与治疗研究进展进行综述,为相关研究提供参考。

徐振晔从脾肾论治肺癌经验

介绍徐振晔教授从脾肾论治肺癌的经验。徐教授认为脾虚精亏是肺癌发生发展的重要因素,治疗以益气健脾、养精解毒为原则,创制了益气健脾、养精解毒特色的中医经验方,在肺癌患者手术后、放射治疗、化学疗法、靶向治疗、免疫治疗等不同时期都充分发挥了中西医结合的优势。并附验案1则。

胆囊切除术后胆汁反流性胃炎中西医研究现状

胆汁反流性胃炎(BRG)的病因众多,可能与胃肠动力紊乱、幽门螺杆菌感染、胆系疾患、外科手术等有关。其中,胆囊切除与BRG的发生关系密切,目前认为,胆囊切除术后BRG发病机制与术后胆囊功能缺失、神经体液调节异常、幽门-十二指肠运动失调、胆汁酸代谢异常等有关。目前中西医结合治疗已成为趋势。本文对近年来胆囊切除术后BRG的中西医发病机制及治疗现状进行综述,以期为临床治疗胆囊切除术后BR G提供诊疗思路。

中西医治疗癌性发热研究进展

通过收集整理近年来中西医治疗癌性发热的相关文献,分别从癌性发热的病因与发病机制、发热特点与诊断标准以及治则治法等方面系统总结目前癌性发热的治疗进展,指出可将中医辨证论治与现代药理研究相结合,将抗癌中药合理组方并配合中药外治等,可在治疗癌性发热的同时控制肿瘤细胞增殖、促进缩小瘤体、改善临床症状。

高彦彬教授从络病论治慢性肾衰经验

慢性肾衰是各类进展性肾脏疾病的最终结局,病机错综复杂,中医对其治疗具有较好疗效。高彦彬教授学术思想师承国医大师吕仁和教授,临证四十载,认为此病属于“络病”范畴,并针对慢性肾衰提出肾元虚衰、肾络瘀结、浊毒内停的基本病机和益气固肾、解毒通络的基本治法。临床上以虚定型,以实定候进行辨证论治,并基于治未病理论,提出慢性肾病三级预防策略。

糖尿病周围神经病变中西医发病机制及治疗的研究进展

糖尿病周围神经病变(DPN)属于糖尿病常见慢性并发症之一,近年来,其发病率和致残率逐年上升。中医认为DPN的根本病机在于脏腑阴阳气血亏虚,瘀血阻络,西医则认为糖脂代谢紊乱、神经营养因子(NTF)缺乏、氧化应激(OS)、自身免疫性疾病都能导致DPN。中医应用方药治疗、针刺治疗及中医物理治疗等多种手段,从多方面、多角度改善DPN患者的临床症状。西医则主要从纠正代谢紊乱、对症镇痛、抗氧化应激、营养神经及外科手术等方面予以治疗。文章通过大量阅读相关文献和结合临床实践观察从传统中医和现代西医两个角度对DPN发病机制及治疗方法进行归纳总结,为该病治疗提供新思路。

胃食管反流病中西医发病机制及药物治疗研究进展

胃食管反流病(Gastroesophageal reflux disease GERD)系胃内容物反流进入食管引起的食管黏膜损伤性炎症疾病,该病发病机制复杂,中西医尚缺乏对其药物作用机理的系统阐述。通过检索近年来国内外相关研究,从中西医两个角度总结GERD的发病机制和药物作用机理,发现该病以胃气上逆为基本病机,无论是经典名方还是新的组方以及单味中药,均体现出多靶点、多通路干预相关因子的转录表达,发挥抑制促炎基因及其受体的表达、下调炎症反应、抑制胃酸胃蛋白酶分泌、增强食管上皮屏障功能等作用促进黏膜损伤恢复。西医常与细胞因子介导的损伤等机制有关,治疗以降低胃酸分泌为主,作用方式及机制单一,因此,中医治疗有独特优势。文章对GERD的中西医病因病机及药物治疗进行探讨,就其病机与作用机制间的联系作一综述,为该病的中西医诊治及药物研发提供新的思路。

刘凤斌对慢性萎缩性胃炎“炎-癌”转化的病机探索与辨治思路

慢性萎缩性胃炎(chronic atrophic gastritis,CAG)是临床上常见的难治性胃病,属于胃癌前病变。刘凤斌教授及其团队历经30余年的探索和实践,提出“脾虚为本,气血湿为标,瘀毒为变”是CAG“炎-癌”转化的病机演变特点。脾胃虚弱为CAG发病的始动因素,贯穿疾病始终;气滞、血瘀、湿阻为CAG“炎-癌”转化的触发和加重因素;瘀毒的形成是CAG进展和转变的关键。辨治应遵循“证镜结合,分期论治”的原则,辨病和辨证相结合,宏观和微观辨证相补充;健脾扶正需贯穿始终。CAG早期阶段(胃黏膜以轻中度萎缩伴或不伴轻度肠上皮化生),其病机以脾胃虚弱为本,伴有气滞、湿阻、血瘀病理因素,治疗以健脾清热、理气活血为基本治法;CAG晚期阶段(胃黏膜重度萎缩伴或不伴中重度肠上皮和/或轻中度上皮内瘤变),基本病机为脾胃虚弱、痰瘀互结、胃络瘀毒,治疗以扶正散结、通络解毒为基本治法,从而构筑中医药阻断胃“炎-癌”转化的整体防线。

甲状腺结节发病机制与中西医治法研究进展

近年来甲状腺结节疾病高发,该病是由甲状腺细胞的局部异常生长而引起的散在病变,中医称其为“瘿病”。其现代医学病因尚不明确,目前认为可能与雌激素的增殖效应、肥胖、糖尿病、遗传基因等因素有关。中医病因病机可概括为肝郁气滞、痰瘀互结、冲任失调三大类,分别对应囊性结节、增生性结节、甲状腺结节伴乳腺结节。在临床治疗方面,中医根据体质辨识,发现甲状腺结节患者最常见的中医体质类型为气郁质、气虚质、阳虚质、湿热质,可采用疏肝解郁、温阳补气、调补冲任等方法辨证论治。现代医学治疗手段主要有外源性补充左旋甲状腺素、甲状腺切除术、微波及射频消融等。探索现代中西医治疗甲状腺结节的方法具有重要意义,在查阅大量文献的基础上,作者从多方面对甲状腺结节中西医研究进展进行了梳理,以期为进一步提高甲状腺结节临床疗效提供参考。