AIM: To evaluate the efficacy of intralesional radiofrequency ablation in the treatment of periorbital syringomas. METHODS: We tried the intralesional radiofrequency ablation for 64 patients with periorbital syringoma...AIM: To evaluate the efficacy of intralesional radiofrequency ablation in the treatment of periorbital syringomas. METHODS: We tried the intralesional radiofrequency ablation for 64 patients with periorbital syringomas from 2007 to 2011. The operation was performed under 2.5 loupe magnifications. The handpiece was assembled with a needle electrode and connected to the radiofrequency ablation apparatus. The electrode was then inserted into the target lesions in dermis and delivering injury to the base of these tumors. Results were assessed clinically by comparing pre- and post-treatment photographs and patient satisfaction rates. RESULTS: Clinical improvement increased with each subsequent treatment session. The percent of patients whose clinic improvement grade were >= 3 after each session was respectively 71.9% (Session1), 83.3% (Session2), and 100% (Session3). The statistical results indicated the concordance of the clinical assessment and the satisfaction level of patients (kappa=0.78 of the session1; kappa=0.82 of the session2). The majority of patients had good or excellent cosmetic results. Postoperatively, there were no permanent side effects or recurrences. CONCLUSION: As a new technique of minimally invasion, the intralesional radiofrequency ablation was found to be an effective, inexpensive, highly precise and safe way of treating periorbital syringomas.展开更多
BACKGROUND Chondroid syringoma(CS)is a rare tumor of the apocrine or eccrine glands.CS of the lower back is rare,and its clinical manifestations are similar to those of lipoma,which is a common misdiagnosis for this d...BACKGROUND Chondroid syringoma(CS)is a rare tumor of the apocrine or eccrine glands.CS of the lower back is rare,and its clinical manifestations are similar to those of lipoma,which is a common misdiagnosis for this disease.CASE SUMMARY A 39-year-old woman presented with a 2-year history of an asymptomatic subcutaneous mass on the lower back.The lesions increased progressively over time.The patient denied any history.Dermatological examination showed that there was a subcutaneous mass,ranging from 3-4 cm in diameter,with a clear boundary on the lower back.The surface of the skin was smooth without ulceration or scaling.Histopathologic examination was consistent with the diagnosis of CS.CONCLUSION CS is a rare tumor of the apocrine or eccrine glands.It usually presents as a wellcircumscribed and single subcutaneous masses.Histopathology showed the tumor was located in the dermis,with nests,sheets,and cords of basal-like cells,mucin deposition,and chondroid structures.We herein report a case of CS located in the lower back.CS of the lower back is rare,and its clinical manifestations are similar to those of lipoma,for which it is commonly misdiagnosed.展开更多
目的研究皮肤混合瘤(mixed tumor of the skin,MTS)的临床及组织病理特点。方法回顾性归纳分析本院1980-2007年26例MTS的临床病理资料。结果26例患者中23例为大汗腺性MTS,其中8例出现毛囊和/或皮脂腺分化,5例呈软骨样变,8例出现多少不...目的研究皮肤混合瘤(mixed tumor of the skin,MTS)的临床及组织病理特点。方法回顾性归纳分析本院1980-2007年26例MTS的临床病理资料。结果26例患者中23例为大汗腺性MTS,其中8例出现毛囊和/或皮脂腺分化,5例呈软骨样变,8例出现多少不等的脂肪组织,8例出现浆细胞样细胞,并有1例出现明显软骨及骨样化生;另外4例小汗腺性MTS出现透明细胞,26例MTS肿瘤间质成分均有不同程度的黏液样物质沉积。结论MTS可向毛囊和/或皮脂腺分化,间质表现多样化。展开更多
基金Supported by Military Medical Specialized Research Fund in the 11th Five-Year Period, China (No. 200626Z000058)
文摘AIM: To evaluate the efficacy of intralesional radiofrequency ablation in the treatment of periorbital syringomas. METHODS: We tried the intralesional radiofrequency ablation for 64 patients with periorbital syringomas from 2007 to 2011. The operation was performed under 2.5 loupe magnifications. The handpiece was assembled with a needle electrode and connected to the radiofrequency ablation apparatus. The electrode was then inserted into the target lesions in dermis and delivering injury to the base of these tumors. Results were assessed clinically by comparing pre- and post-treatment photographs and patient satisfaction rates. RESULTS: Clinical improvement increased with each subsequent treatment session. The percent of patients whose clinic improvement grade were >= 3 after each session was respectively 71.9% (Session1), 83.3% (Session2), and 100% (Session3). The statistical results indicated the concordance of the clinical assessment and the satisfaction level of patients (kappa=0.78 of the session1; kappa=0.82 of the session2). The majority of patients had good or excellent cosmetic results. Postoperatively, there were no permanent side effects or recurrences. CONCLUSION: As a new technique of minimally invasion, the intralesional radiofrequency ablation was found to be an effective, inexpensive, highly precise and safe way of treating periorbital syringomas.
基金Supported by Shenzhen Sanming Project,No.SZSM201812059Shenzhen Key Medical Discipline Construction Fund,No.SZXK040。
文摘BACKGROUND Chondroid syringoma(CS)is a rare tumor of the apocrine or eccrine glands.CS of the lower back is rare,and its clinical manifestations are similar to those of lipoma,which is a common misdiagnosis for this disease.CASE SUMMARY A 39-year-old woman presented with a 2-year history of an asymptomatic subcutaneous mass on the lower back.The lesions increased progressively over time.The patient denied any history.Dermatological examination showed that there was a subcutaneous mass,ranging from 3-4 cm in diameter,with a clear boundary on the lower back.The surface of the skin was smooth without ulceration or scaling.Histopathologic examination was consistent with the diagnosis of CS.CONCLUSION CS is a rare tumor of the apocrine or eccrine glands.It usually presents as a wellcircumscribed and single subcutaneous masses.Histopathology showed the tumor was located in the dermis,with nests,sheets,and cords of basal-like cells,mucin deposition,and chondroid structures.We herein report a case of CS located in the lower back.CS of the lower back is rare,and its clinical manifestations are similar to those of lipoma,for which it is commonly misdiagnosed.
文摘目的研究皮肤混合瘤(mixed tumor of the skin,MTS)的临床及组织病理特点。方法回顾性归纳分析本院1980-2007年26例MTS的临床病理资料。结果26例患者中23例为大汗腺性MTS,其中8例出现毛囊和/或皮脂腺分化,5例呈软骨样变,8例出现多少不等的脂肪组织,8例出现浆细胞样细胞,并有1例出现明显软骨及骨样化生;另外4例小汗腺性MTS出现透明细胞,26例MTS肿瘤间质成分均有不同程度的黏液样物质沉积。结论MTS可向毛囊和/或皮脂腺分化,间质表现多样化。
