BACKGROUND Hypertensive intracerebral hemorrhage is a common critical disease of the nervous system,comprising one fifth of all acute cerebrovascular diseases and has a high disability and mortality rate.It severely a...BACKGROUND Hypertensive intracerebral hemorrhage is a common critical disease of the nervous system,comprising one fifth of all acute cerebrovascular diseases and has a high disability and mortality rate.It severely affects the patients’quality of life.AIM To analyze the short-term effect and long-term prognosis of neuroendoscopic minimally invasive surgery for hypertensive intracerebral hemorrhage.METHODS From March 2018 to May 2020,118 patients with hypertensive intracerebral hemorrhage were enrolled in our study and divided into a control group and observation group according to the surgical plan.The control group used a hard-channel minimally invasive puncture and drainage procedure.The observation group underwent minimally invasive neuroendoscopic surgery.The changes in the levels of serum P substances(SP),inflammatory factors[tumor necrosis factor-α,interleukin-6(IL-6),IL-10],and the National Hospital Stroke Scale(NIHSS)and Barthel index scores were recorded.Surgery related indicators and prognosis were compared between the two groups.RESULTS The operation time(105.26±28.35)of the observation group was min longer than that of the control group,and the volume of intraoperative bleeding was 45.36±10.17 mL more than that of the control group.The hematoma clearance rates were 88.58%±4.69%and 94.47%±4.02%higher than those of the control group at 48 h and 72 h,respectively.Good prognosis rate(86.44%)was higher in the observation group than in the control group,and complication rate(5.08%)was not significantly different from that of the control group(P>0.05).The SP level and Barthel index score of the two groups increased(P<0.05)and the inflam-matory factors and NIHSS score decreased(P<0.05).The cytokine levels,NIHSS score,and Barthel index score were better in the observation group than in the control group(P<0.05).CONCLUSION Neuroendoscopic minimally invasive surgery is more complicated than hard channel minimally invasive puncture drainage in the treatment of hypertensive intracerebral hemorrhage;however,hematoma clearance is more thorough,and the short-term effect and long-term prognosis are better than hard channel minimally invasive puncture drainage.展开更多
目的探讨CT立体定向微创软管道置管配合尿激酶治疗高血压性脑出血的效果。方法回顾性分析北京中医药大学东方医院2012年10月~2017年5月收治的高血压性脑出血80例患者的临床资料,其中采用内科保守治疗的40例患者设为对照组,采用CT立体定...目的探讨CT立体定向微创软管道置管配合尿激酶治疗高血压性脑出血的效果。方法回顾性分析北京中医药大学东方医院2012年10月~2017年5月收治的高血压性脑出血80例患者的临床资料,其中采用内科保守治疗的40例患者设为对照组,采用CT立体定向微创软通道置管配合尿激酶治疗的40例患者设为观察组,对两组的日常生活活动能力(ADL)、格拉斯哥预后评分(GOS)、格拉斯哥昏迷评分(GCS)、Barthel指数进行比较。结果两组治疗30 d ADL分级改善比较,差异无统计学意义(P>0.05)。观察组治疗30、90 d GOS评分和治疗5 d GCS评分均明显高于对照组,治疗前与治疗30 d Barthel指数差值亦高于对照组,差异均有统计学意义(均P<0.05)。观察组并发症发生率明显低于对照组,差异有统计学意义(P<0.05)。结论 CT立体定向微创软通道置管配合尿激酶治疗高血压性脑出血的效果显著优于内科保守治疗,能够提高患者日常生活活动能力,减少并发症,具有积极的临床使用价值。展开更多
目的：分析简易头皮定位下锥颅软通道置管引流治疗外伤性脑内血肿的效果。方法对34例（格拉斯哥评分6~14分）未发生脑疝的外伤性脑内血肿患者行头皮简易定位下锥颅软通道置管引流治疗，术后给予尿激酶盐水溶解血肿。结果33例疗效满意，...目的：分析简易头皮定位下锥颅软通道置管引流治疗外伤性脑内血肿的效果。方法对34例（格拉斯哥评分6~14分）未发生脑疝的外伤性脑内血肿患者行头皮简易定位下锥颅软通道置管引流治疗，术后给予尿激酶盐水溶解血肿。结果33例疗效满意，患者均在8 d 内清除血肿量的80％~90％。引流时间3~5天19例，6~8天14例，平均住院时间24天。1例患者因术后血肿扩大、意识障碍加深行开颅去骨瓣减压。33例患者随访6~24个月。按日常生活能力（ADL）评定患者远期疗效，Ⅰ级：25例，Ⅱ级：3例，Ⅲ级：3例，Ⅳ级：1例，Ⅴ级：1例；复查头颅 CT发生轻度脑积水仅1例（2.9％）。结论对于未发生脑疝、病情相对稳定的颅脑损伤患者，锥颅治疗外伤性脑内血肿简单易行、创伤小、恢复快，并发症少。展开更多
文摘BACKGROUND Hypertensive intracerebral hemorrhage is a common critical disease of the nervous system,comprising one fifth of all acute cerebrovascular diseases and has a high disability and mortality rate.It severely affects the patients’quality of life.AIM To analyze the short-term effect and long-term prognosis of neuroendoscopic minimally invasive surgery for hypertensive intracerebral hemorrhage.METHODS From March 2018 to May 2020,118 patients with hypertensive intracerebral hemorrhage were enrolled in our study and divided into a control group and observation group according to the surgical plan.The control group used a hard-channel minimally invasive puncture and drainage procedure.The observation group underwent minimally invasive neuroendoscopic surgery.The changes in the levels of serum P substances(SP),inflammatory factors[tumor necrosis factor-α,interleukin-6(IL-6),IL-10],and the National Hospital Stroke Scale(NIHSS)and Barthel index scores were recorded.Surgery related indicators and prognosis were compared between the two groups.RESULTS The operation time(105.26±28.35)of the observation group was min longer than that of the control group,and the volume of intraoperative bleeding was 45.36±10.17 mL more than that of the control group.The hematoma clearance rates were 88.58%±4.69%and 94.47%±4.02%higher than those of the control group at 48 h and 72 h,respectively.Good prognosis rate(86.44%)was higher in the observation group than in the control group,and complication rate(5.08%)was not significantly different from that of the control group(P>0.05).The SP level and Barthel index score of the two groups increased(P<0.05)and the inflam-matory factors and NIHSS score decreased(P<0.05).The cytokine levels,NIHSS score,and Barthel index score were better in the observation group than in the control group(P<0.05).CONCLUSION Neuroendoscopic minimally invasive surgery is more complicated than hard channel minimally invasive puncture drainage in the treatment of hypertensive intracerebral hemorrhage;however,hematoma clearance is more thorough,and the short-term effect and long-term prognosis are better than hard channel minimally invasive puncture drainage.
文摘目的探讨CT立体定向微创软管道置管配合尿激酶治疗高血压性脑出血的效果。方法回顾性分析北京中医药大学东方医院2012年10月~2017年5月收治的高血压性脑出血80例患者的临床资料,其中采用内科保守治疗的40例患者设为对照组,采用CT立体定向微创软通道置管配合尿激酶治疗的40例患者设为观察组,对两组的日常生活活动能力(ADL)、格拉斯哥预后评分(GOS)、格拉斯哥昏迷评分(GCS)、Barthel指数进行比较。结果两组治疗30 d ADL分级改善比较,差异无统计学意义(P>0.05)。观察组治疗30、90 d GOS评分和治疗5 d GCS评分均明显高于对照组,治疗前与治疗30 d Barthel指数差值亦高于对照组,差异均有统计学意义(均P<0.05)。观察组并发症发生率明显低于对照组,差异有统计学意义(P<0.05)。结论 CT立体定向微创软通道置管配合尿激酶治疗高血压性脑出血的效果显著优于内科保守治疗,能够提高患者日常生活活动能力,减少并发症,具有积极的临床使用价值。
文摘目的：分析简易头皮定位下锥颅软通道置管引流治疗外伤性脑内血肿的效果。方法对34例（格拉斯哥评分6~14分）未发生脑疝的外伤性脑内血肿患者行头皮简易定位下锥颅软通道置管引流治疗，术后给予尿激酶盐水溶解血肿。结果33例疗效满意，患者均在8 d 内清除血肿量的80％~90％。引流时间3~5天19例，6~8天14例，平均住院时间24天。1例患者因术后血肿扩大、意识障碍加深行开颅去骨瓣减压。33例患者随访6~24个月。按日常生活能力（ADL）评定患者远期疗效，Ⅰ级：25例，Ⅱ级：3例，Ⅲ级：3例，Ⅳ级：1例，Ⅴ级：1例；复查头颅 CT发生轻度脑积水仅1例（2.9％）。结论对于未发生脑疝、病情相对稳定的颅脑损伤患者，锥颅治疗外伤性脑内血肿简单易行、创伤小、恢复快，并发症少。
