A highly practical asymmetric cpoxidation procedure for the synthesis of optically pure epoxychromans has been developed which employs 30% hydrogen peroxied as the oxidant and the Jacobsen-catalyst as the catalyst. Th...A highly practical asymmetric cpoxidation procedure for the synthesis of optically pure epoxychromans has been developed which employs 30% hydrogen peroxied as the oxidant and the Jacobsen-catalyst as the catalyst. The presence of imidazole has a significant effect on epoxidation rates and total turnovers. A variety of chromene derivatives were converted into corresponding epoxides of 89～100% ee in 72～92% isolated yields.展开更多
The authors have prepared supramolecular systems as artificial metalloproteins composed of several chiral salen-type Mn（II） and Co（II） complexes in a HSA （human serum albumin） matrix. The docking was discussed b...The authors have prepared supramolecular systems as artificial metalloproteins composed of several chiral salen-type Mn（II） and Co（II） complexes in a HSA （human serum albumin） matrix. The docking was discussed by UV-vis spectral changes and a ligand-protein docking simulation program. After linearly polarized UV light irradiation, that anisotropy of molecular orientation of the complexes increased was confirmed by polarized IR spectra. The authors have observed that the electrochemical behavior of the aligned complexes incorporating diphenyl groups in HSA can be tuned without UV radiation damage of HSA higher structures.展开更多
文摘A highly practical asymmetric cpoxidation procedure for the synthesis of optically pure epoxychromans has been developed which employs 30% hydrogen peroxied as the oxidant and the Jacobsen-catalyst as the catalyst. The presence of imidazole has a significant effect on epoxidation rates and total turnovers. A variety of chromene derivatives were converted into corresponding epoxides of 89～100% ee in 72～92% isolated yields.
文摘The authors have prepared supramolecular systems as artificial metalloproteins composed of several chiral salen-type Mn（II） and Co（II） complexes in a HSA （human serum albumin） matrix. The docking was discussed by UV-vis spectral changes and a ligand-protein docking simulation program. After linearly polarized UV light irradiation, that anisotropy of molecular orientation of the complexes increased was confirmed by polarized IR spectra. The authors have observed that the electrochemical behavior of the aligned complexes incorporating diphenyl groups in HSA can be tuned without UV radiation damage of HSA higher structures.
基金supported by the National Natural Science Foundation of China(20972015)the Natural Science Foundation of Beijing(Grant2082016)a joint project of Beijing Municipal Education Commission(China)
