Based on the situation that the statistic of the missile facilities' stability was small, and the conventional big example preview method was no longer of use. So, this article used the gray GM (1, 1) model to prev...Based on the situation that the statistic of the missile facilities' stability was small, and the conventional big example preview method was no longer of use. So, this article used the gray GM (1, 1) model to preview a facility' s stability .The gray GM (1, 1) model doesn' t need a large number of example statistics, and it is also accurate, so this model solved the problem in the analyze and preview of the stability of the missile' s electronic facility system, and it has possibility to imply to engineering use.展开更多
This paper present a simulation study of an evolutionary algorithms, Particle Swarm Optimization PSO algorithm to optimize likelihood function of ARMA(1, 1) model, where maximizing likelihood function is equivalent ...This paper present a simulation study of an evolutionary algorithms, Particle Swarm Optimization PSO algorithm to optimize likelihood function of ARMA(1, 1) model, where maximizing likelihood function is equivalent to maximizing its logarithm, so the objective function 'obj.fun' is maximizing log-likelihood function. Monte Carlo method adapted for implementing and designing the experiments of this simulation. This study including a comparison among three versions of PSO algorithm “Constriction coefficient CCPSO, Inertia weight IWPSO, and Fully Informed FIPSO”, the experiments designed by setting different values of model parameters al, bs sample size n, moreover the parameters of PSO algorithms. MSE used as test statistic to measure the efficiency PSO to estimate model. The results show the ability of PSO to estimate ARMA' s parameters, and the minimum values of MSE getting for COPSO.展开更多
We propose the Dantzig selector based on the l_(1-q)(1<q≤2)minimization model for the sparse signal recovery.First,we discuss some properties of l_(1-q)minimization model and give some useful inequalities.Then,we ...We propose the Dantzig selector based on the l_(1-q)(1<q≤2)minimization model for the sparse signal recovery.First,we discuss some properties of l_(1-q)minimization model and give some useful inequalities.Then,we give a sufficient condition based on the restricted isometry property for the stable recovery of signals.The l_(1-2)minimization model of Yin-Lou-He is extended to the l_(1-q)minimization model.展开更多
To create a new prediction model, the unbiased GM (1,1) model is optimized by the five-point slide method in this paper. Then, based on the occurrence areas of dce blast in Enshi District during 1995 -2004, the new ...To create a new prediction model, the unbiased GM (1,1) model is optimized by the five-point slide method in this paper. Then, based on the occurrence areas of dce blast in Enshi District during 1995 -2004, the new model and unbiased GM (1, 1 ) model are applied to predict the occurrence areas of rice blast during 2005 -2010. Predicting outcomes show that the prediction accuracy of five-point unbiased sliding optimized GM (1, 1 ) model is higher than the unbiased GM (1,1) model. Finally, combined with the prediction results, the author provides some suggestion for Enshi District in the prevention and control of rice blast in 2010.展开更多
Recent advances in understanding type 1 diabetes(T1D)highlight the complexity of managing hypoglycemia,a frequent and perilous complication of diabetes therapy.This letter delves into a novel study by Jin et al,which ...Recent advances in understanding type 1 diabetes(T1D)highlight the complexity of managing hypoglycemia,a frequent and perilous complication of diabetes therapy.This letter delves into a novel study by Jin et al,which elucidates the role of intestinal glucagon-like peptide-1(GLP-1)in the counterregulatory response to hypoglycemia in T1D models.The study employed immunofluorescence,Western blotting,and enzyme-linked immunosorbent assay to track changes in GLP-1 and its receptor expression in diabetic mice subjected to recurrent hypoglycemic episodes.Findings indicate a significant increase in intestinal GLP-1 and GLP-1 receptor expression,correlating with diminished adrenal and glucagon responses,crucial for glucose stabilization during hypoglycemic events.This letter aims to explore the implications of these findings for future therapeutic strategies and the broader understanding of T1D management.展开更多
Evapotranspiration is the most important expenditure item in the water balance of terrestrial ecosystems,and accurate evapotranspiration modeling is of great significance for hydrological,ecological,agricultural,and w...Evapotranspiration is the most important expenditure item in the water balance of terrestrial ecosystems,and accurate evapotranspiration modeling is of great significance for hydrological,ecological,agricultural,and water resource management.Artificial forests are an important means of vegetation restoration in the western Loess Plateau,and accurate estimates of their evapotranspiration are essential to the management and development of water use strategies for artificial forests.This study estimated the soil moisture and evapotranspiration based on the HYDRUS-1D model for the artificial Platycladus orientalis(L.)Franco forest in western mountains of Loess Plateau,China from 20 April to 31 October,2023.Moreover,the influence factors were identified by combining the correlation coefficient method and the principal component analysis(PCA)method.The results showed that HYDRUS-1D model had strong applicability in portraying hydrological processes in this area and revealed soil water surplus from 20 April to 31 October,2023.The soil water accumulation was 49.64 mm;the potential evapotranspiration(ET_(p))was 809.67 mm,which was divided into potential evaporation(E_(p);95.07 mm)and potential transpiration(T_(p);714.60 mm);and the actual evapotranspiration(ET_(a))was 580.27 mm,which was divided into actual evaporation(E_(a);68.27 mm)and actual transpiration(T_(a);512.00 mm).From April to October 2023,the ET_(p),E_(p),T_(p),ET_(a),E_(a),and T_(a) first increased and then decreased on both monthly and daily scales,exhibiting a single-peak type trend.The average ratio of T_(a)/ET_(a) was 0.88,signifying that evapotranspiration mainly stemmed from transpiration in this area.The ratio of ET_(a)/ET_(p) was 0.72,indicating that this artificial forest suffered from obvious drought stress.The ET_(p) was significantly positively correlated with ET_(a),and the R^(2) values on the monthly and daily scales were 0.9696 and 0.9635(P<0.05),respectively.Furthermore,ET_(a) was significantly positively correlated with temperature,solar radiation,and wind speed,and negatively correlated with relative humidity and precipitation(P<0.05);and temperature exhibited the highest correlation with ET_(a).Thus,ET_(p) and temperature were the decisive contributors to ET_(a) in this area.The findings provide an effective method for simulating regional evapotranspiration and theoretical reference for water management of artificial forests,and deepen understanding of effects of each influence factors on ET_(a) in arid areas.展开更多
Background:This study aimed to construct and characterize a humanized influenza mouse model expressing hST6GAL1.Methods:Humanized fragments,consisting of the endothelial cell-specific K18 promoter,human ST6GAL1-encodi...Background:This study aimed to construct and characterize a humanized influenza mouse model expressing hST6GAL1.Methods:Humanized fragments,consisting of the endothelial cell-specific K18 promoter,human ST6GAL1-encoding gene,and luciferase gene,were microinjected into the fertilized eggs of mice.The manipulated embryos were transferred into the oviducts of pseudopregnant female mice.The offspring were identified using PCR.Mice exhibiting elevated expression of the hST6GAL1 gene were selectively bred for propagation,and in vivo analysis was performed for screening.Expression of the humanized gene was tested by performing immunohistochemical(IHC)analysis.Hematologic and biochemical analyses using the whole blood and serum of humanized hST6GAL1 mice were performed.Results:Successful integration of the human ST6GAL1 gene into the mouse genome led to the overexpression of human SiaT ST6GAL1.Seven mice were identified as carrying copies of the humanized gene,and the in vivo analysis indicated that hST6GAL1gene expression in positive mice mirrored influenza virus infection characteristics.The IHC results revealed that hST6GAL1 was expressed in the lungs of humanized mice.Moreover,the hematologic and biochemical parameters of the positive mice were within the normal range.Conclusion:A humanized influenza mouse model expressing the hST6GAL1 gene was successfully established and characterized.展开更多
文摘Based on the situation that the statistic of the missile facilities' stability was small, and the conventional big example preview method was no longer of use. So, this article used the gray GM (1, 1) model to preview a facility' s stability .The gray GM (1, 1) model doesn' t need a large number of example statistics, and it is also accurate, so this model solved the problem in the analyze and preview of the stability of the missile' s electronic facility system, and it has possibility to imply to engineering use.
文摘This paper present a simulation study of an evolutionary algorithms, Particle Swarm Optimization PSO algorithm to optimize likelihood function of ARMA(1, 1) model, where maximizing likelihood function is equivalent to maximizing its logarithm, so the objective function 'obj.fun' is maximizing log-likelihood function. Monte Carlo method adapted for implementing and designing the experiments of this simulation. This study including a comparison among three versions of PSO algorithm “Constriction coefficient CCPSO, Inertia weight IWPSO, and Fully Informed FIPSO”, the experiments designed by setting different values of model parameters al, bs sample size n, moreover the parameters of PSO algorithms. MSE used as test statistic to measure the efficiency PSO to estimate model. The results show the ability of PSO to estimate ARMA' s parameters, and the minimum values of MSE getting for COPSO.
基金supported by the National Natural Science Foundation of China“Variable exponential function spaces on variable anisotropic Euclidean spaces and their applications”(12261083),“Harmonic analysis on affine symmetric spaces”(12161083).
文摘We propose the Dantzig selector based on the l_(1-q)(1<q≤2)minimization model for the sparse signal recovery.First,we discuss some properties of l_(1-q)minimization model and give some useful inequalities.Then,we give a sufficient condition based on the restricted isometry property for the stable recovery of signals.The l_(1-2)minimization model of Yin-Lou-He is extended to the l_(1-q)minimization model.
基金Supported by Science Research Project of Department of Education of Hubei Province (B20092901)~~
文摘To create a new prediction model, the unbiased GM (1,1) model is optimized by the five-point slide method in this paper. Then, based on the occurrence areas of dce blast in Enshi District during 1995 -2004, the new model and unbiased GM (1, 1 ) model are applied to predict the occurrence areas of rice blast during 2005 -2010. Predicting outcomes show that the prediction accuracy of five-point unbiased sliding optimized GM (1, 1 ) model is higher than the unbiased GM (1,1) model. Finally, combined with the prediction results, the author provides some suggestion for Enshi District in the prevention and control of rice blast in 2010.
文摘Recent advances in understanding type 1 diabetes(T1D)highlight the complexity of managing hypoglycemia,a frequent and perilous complication of diabetes therapy.This letter delves into a novel study by Jin et al,which elucidates the role of intestinal glucagon-like peptide-1(GLP-1)in the counterregulatory response to hypoglycemia in T1D models.The study employed immunofluorescence,Western blotting,and enzyme-linked immunosorbent assay to track changes in GLP-1 and its receptor expression in diabetic mice subjected to recurrent hypoglycemic episodes.Findings indicate a significant increase in intestinal GLP-1 and GLP-1 receptor expression,correlating with diminished adrenal and glucagon responses,crucial for glucose stabilization during hypoglycemic events.This letter aims to explore the implications of these findings for future therapeutic strategies and the broader understanding of T1D management.
基金financially supported by the National Natural Science Foundation of China(42071047,41771035)the Basic Research Innovation Group Project of Gansu Province(22JR5RA129)the Excellent Doctoral Program in Gansu Province(24JRRA152).
文摘Evapotranspiration is the most important expenditure item in the water balance of terrestrial ecosystems,and accurate evapotranspiration modeling is of great significance for hydrological,ecological,agricultural,and water resource management.Artificial forests are an important means of vegetation restoration in the western Loess Plateau,and accurate estimates of their evapotranspiration are essential to the management and development of water use strategies for artificial forests.This study estimated the soil moisture and evapotranspiration based on the HYDRUS-1D model for the artificial Platycladus orientalis(L.)Franco forest in western mountains of Loess Plateau,China from 20 April to 31 October,2023.Moreover,the influence factors were identified by combining the correlation coefficient method and the principal component analysis(PCA)method.The results showed that HYDRUS-1D model had strong applicability in portraying hydrological processes in this area and revealed soil water surplus from 20 April to 31 October,2023.The soil water accumulation was 49.64 mm;the potential evapotranspiration(ET_(p))was 809.67 mm,which was divided into potential evaporation(E_(p);95.07 mm)and potential transpiration(T_(p);714.60 mm);and the actual evapotranspiration(ET_(a))was 580.27 mm,which was divided into actual evaporation(E_(a);68.27 mm)and actual transpiration(T_(a);512.00 mm).From April to October 2023,the ET_(p),E_(p),T_(p),ET_(a),E_(a),and T_(a) first increased and then decreased on both monthly and daily scales,exhibiting a single-peak type trend.The average ratio of T_(a)/ET_(a) was 0.88,signifying that evapotranspiration mainly stemmed from transpiration in this area.The ratio of ET_(a)/ET_(p) was 0.72,indicating that this artificial forest suffered from obvious drought stress.The ET_(p) was significantly positively correlated with ET_(a),and the R^(2) values on the monthly and daily scales were 0.9696 and 0.9635(P<0.05),respectively.Furthermore,ET_(a) was significantly positively correlated with temperature,solar radiation,and wind speed,and negatively correlated with relative humidity and precipitation(P<0.05);and temperature exhibited the highest correlation with ET_(a).Thus,ET_(p) and temperature were the decisive contributors to ET_(a) in this area.The findings provide an effective method for simulating regional evapotranspiration and theoretical reference for water management of artificial forests,and deepen understanding of effects of each influence factors on ET_(a) in arid areas.
基金National Key Research and Development Program of China,Grant/Award Number:2021YFC2301403 and 2022YFF0711000。
文摘Background:This study aimed to construct and characterize a humanized influenza mouse model expressing hST6GAL1.Methods:Humanized fragments,consisting of the endothelial cell-specific K18 promoter,human ST6GAL1-encoding gene,and luciferase gene,were microinjected into the fertilized eggs of mice.The manipulated embryos were transferred into the oviducts of pseudopregnant female mice.The offspring were identified using PCR.Mice exhibiting elevated expression of the hST6GAL1 gene were selectively bred for propagation,and in vivo analysis was performed for screening.Expression of the humanized gene was tested by performing immunohistochemical(IHC)analysis.Hematologic and biochemical analyses using the whole blood and serum of humanized hST6GAL1 mice were performed.Results:Successful integration of the human ST6GAL1 gene into the mouse genome led to the overexpression of human SiaT ST6GAL1.Seven mice were identified as carrying copies of the humanized gene,and the in vivo analysis indicated that hST6GAL1gene expression in positive mice mirrored influenza virus infection characteristics.The IHC results revealed that hST6GAL1 was expressed in the lungs of humanized mice.Moreover,the hematologic and biochemical parameters of the positive mice were within the normal range.Conclusion:A humanized influenza mouse model expressing the hST6GAL1 gene was successfully established and characterized.