Objective: To explore and analyze the effect of acupoint application combined with microwave treatment on the intestinal barrier dysfunction with moderately severe acute pancreatitis. Methods: A convenient sample of 9...Objective: To explore and analyze the effect of acupoint application combined with microwave treatment on the intestinal barrier dysfunction with moderately severe acute pancreatitis. Methods: A convenient sample of 90 moderately severe acute pancreatitis was selected from March 2017 to December 2017 in the comprehensive hospital with third grade in Tianjin. The patients were divided into group A (acupoint application combined with microwave treatment), group B (acupoint application) and group C (routine nursing). Thirty patients were included in each group. This study need to get the informed consent of the patients. Acupoint application combined with microwave treatment was used, basing on routine nursing measures in group A. Acupoint application was used by the same way and the same traditional Chinese medicine ,basing on routine nursing measures in group B. Routine nursing used in group C. C-reactive protein and the score of intestinal function were measured on 3 th day, 7 th day and 10 th day, after intervention. To record the effective ratio of the treatment after 10 days of intervention. Results: There are significant statistical difference among the three group after intervention (P < 0.05). Conclusion: In some way, acupoint application combined with microwave treatment are able to decrease the time about the recovery of intestinal barrier dysfunction in moderately severe acute pancreatitis and to alleviate the suffering of patients.展开更多
Objective:To explore the curative effect of Chaishao Chengqi Decoction on moderate to severe acute pancreatitis of heat stagnation and Fu-organ excess type and its effect on inflammatory reaction,and to provide new id...Objective:To explore the curative effect of Chaishao Chengqi Decoction on moderate to severe acute pancreatitis of heat stagnation and Fu-organ excess type and its effect on inflammatory reaction,and to provide new ideas for clinical treatment and prognosis evaluation.Methods:60 patients with moderate to severe acute pancreatitis of heat stagnation and Fu-organ excess type from June 2017 to June 2019 were randomly divided into control group treated with conventional therapy and treatment group treated with Chaishao Chengqi Decoction for 2 weeks.The differences of clinical efficacy and TCM syndromes between the two groups were compared.Ranson score,Balthazar CTSI score,SIRS score and modified Marshall score were recorded before and after treatment.The levels of inflammatory factors and oxidative stress-related molecules were compared before and after treatment.Result:After treatment,the total effective rates of the control group and the treatment group were 80.0%and 93.3%,respectively,with statistical difference(χ2=8.845,P=0.027);after treatment,the total effective rates of TCM syndromes evaluation of the control group and the treatment group were 76.7%and 93.3%,respectively,with statistical difference(χ2=10.024,P=0.012);after treatment,the Ranson score,Balthazar CTSI score,SIRS score and improved Marshall score were all significantly decreased(P<0.05),and the decrease was more significant in the treatment group(P<0.05);after treatment,the serum levels of TNF-α,IL-6 and MDA were significantly decreased in both groups,and superoxide dismutase(SOD)was significantly increased(P<0.05),and the treatment group improved more(P<0.05).Conclusion:Chaishao Chengqi Decoction has a good curative effect on moderate to severe acute pancreatitis of heat stagnation and Fu-organ excess type,and can effectively improve inflammatory response and oxidative stress,which has a high clinical significance.展开更多
目的探讨中度急性胰腺炎（MSAP）的临床特点，为今后的临床诊治提供参考。方法回顾性分析2008年6月至2013年12月急性胰腺炎（AP）362例[分为轻度急性胰腺炎（MAP）、MSAP和重度急性胰腺炎（SAP）三组]患者的临床资料。结果362倒AP患者中...目的探讨中度急性胰腺炎（MSAP）的临床特点，为今后的临床诊治提供参考。方法回顾性分析2008年6月至2013年12月急性胰腺炎（AP）362例[分为轻度急性胰腺炎（MAP）、MSAP和重度急性胰腺炎（SAP）三组]患者的临床资料。结果362倒AP患者中MSAP178例（49．2％）。MSAP患者病因以胆石症及高脂血症为主。与MAP比较，MSAP患者的住院时间更长（12d vs 16d），但明显短于SAP（16d vs 40d，P=0．00）。三组BISAP评分差并有显著性（P〈0．01）。MSAP患者86．0％出现局部并发症，43．2％并发SIRS，仅12．9％并发器官功能衰竭，发生率均显著低于SAP。MSAP患者ICU监护需要率及监护天数、器官支持治疗需要率均明显低于SAP（P〈0．01）。178例MSAP患者均治愈好转出院，而SAP患者35％死亡。结论MSAP并发症以局部并发症为主，全身并发症及器官功能衰竭发生率低。ICU监护需要率及器官支持需要率低，监护时间短，预后好，病死率低。展开更多
文摘Objective: To explore and analyze the effect of acupoint application combined with microwave treatment on the intestinal barrier dysfunction with moderately severe acute pancreatitis. Methods: A convenient sample of 90 moderately severe acute pancreatitis was selected from March 2017 to December 2017 in the comprehensive hospital with third grade in Tianjin. The patients were divided into group A (acupoint application combined with microwave treatment), group B (acupoint application) and group C (routine nursing). Thirty patients were included in each group. This study need to get the informed consent of the patients. Acupoint application combined with microwave treatment was used, basing on routine nursing measures in group A. Acupoint application was used by the same way and the same traditional Chinese medicine ,basing on routine nursing measures in group B. Routine nursing used in group C. C-reactive protein and the score of intestinal function were measured on 3 th day, 7 th day and 10 th day, after intervention. To record the effective ratio of the treatment after 10 days of intervention. Results: There are significant statistical difference among the three group after intervention (P < 0.05). Conclusion: In some way, acupoint application combined with microwave treatment are able to decrease the time about the recovery of intestinal barrier dysfunction in moderately severe acute pancreatitis and to alleviate the suffering of patients.
基金Zhangjiagang municipal commission of health and family planning system youth science and technology project in 2018(ZJGQNLKJ201813).
文摘Objective:To explore the curative effect of Chaishao Chengqi Decoction on moderate to severe acute pancreatitis of heat stagnation and Fu-organ excess type and its effect on inflammatory reaction,and to provide new ideas for clinical treatment and prognosis evaluation.Methods:60 patients with moderate to severe acute pancreatitis of heat stagnation and Fu-organ excess type from June 2017 to June 2019 were randomly divided into control group treated with conventional therapy and treatment group treated with Chaishao Chengqi Decoction for 2 weeks.The differences of clinical efficacy and TCM syndromes between the two groups were compared.Ranson score,Balthazar CTSI score,SIRS score and modified Marshall score were recorded before and after treatment.The levels of inflammatory factors and oxidative stress-related molecules were compared before and after treatment.Result:After treatment,the total effective rates of the control group and the treatment group were 80.0%and 93.3%,respectively,with statistical difference(χ2=8.845,P=0.027);after treatment,the total effective rates of TCM syndromes evaluation of the control group and the treatment group were 76.7%and 93.3%,respectively,with statistical difference(χ2=10.024,P=0.012);after treatment,the Ranson score,Balthazar CTSI score,SIRS score and improved Marshall score were all significantly decreased(P<0.05),and the decrease was more significant in the treatment group(P<0.05);after treatment,the serum levels of TNF-α,IL-6 and MDA were significantly decreased in both groups,and superoxide dismutase(SOD)was significantly increased(P<0.05),and the treatment group improved more(P<0.05).Conclusion:Chaishao Chengqi Decoction has a good curative effect on moderate to severe acute pancreatitis of heat stagnation and Fu-organ excess type,and can effectively improve inflammatory response and oxidative stress,which has a high clinical significance.
文摘目的探讨中度急性胰腺炎（MSAP）的临床特点，为今后的临床诊治提供参考。方法回顾性分析2008年6月至2013年12月急性胰腺炎（AP）362例[分为轻度急性胰腺炎（MAP）、MSAP和重度急性胰腺炎（SAP）三组]患者的临床资料。结果362倒AP患者中MSAP178例（49．2％）。MSAP患者病因以胆石症及高脂血症为主。与MAP比较，MSAP患者的住院时间更长（12d vs 16d），但明显短于SAP（16d vs 40d，P=0．00）。三组BISAP评分差并有显著性（P〈0．01）。MSAP患者86．0％出现局部并发症，43．2％并发SIRS，仅12．9％并发器官功能衰竭，发生率均显著低于SAP。MSAP患者ICU监护需要率及监护天数、器官支持治疗需要率均明显低于SAP（P〈0．01）。178例MSAP患者均治愈好转出院，而SAP患者35％死亡。结论MSAP并发症以局部并发症为主，全身并发症及器官功能衰竭发生率低。ICU监护需要率及器官支持需要率低，监护时间短，预后好，病死率低。
