This study develops an Enhanced Threshold Based Energy Detection approach(ETBED)for spectrum sensing in a cognitive radio network.The threshold identification method is implemented in the received signal at the second...This study develops an Enhanced Threshold Based Energy Detection approach(ETBED)for spectrum sensing in a cognitive radio network.The threshold identification method is implemented in the received signal at the secondary user based on the square law.The proposed method is implemented with the signal transmission of multiple outputs-orthogonal frequency division multiplexing.Additionally,the proposed method is considered the dynamic detection threshold adjustments and energy identification spectrum sensing technique in cognitive radio systems.In the dynamic threshold,the signal ratio-based threshold is fixed.The threshold is computed by considering the Modified Black Widow Optimization Algorithm(MBWO).So,the proposed methodology is a combination of dynamic threshold detection and MBWO.The general threshold-based detection technique has different limitations such as the inability optimal signal threshold for determining the presence of the primary user signal.These limitations undermine the sensing accuracy of the energy identification technique.Hence,the ETBED technique is developed to enhance the energy efficiency of cognitive radio networks.The projected approach is executed and analyzed with performance and comparison analysis.The proposed method is contrasted with the conventional techniques of theWhale Optimization Algorithm(WOA)and GreyWolf Optimization(GWO).It indicated superior results,achieving a high average throughput of 2.2 Mbps and an energy efficiency of 3.8,outperforming conventional techniques.展开更多
BACKGROUND Previous studies have validated the efficacy of both magnetic compression and surgical techniques in creating rabbit tracheoesophageal fistula(TEF)models.Magnetic compression achieves a 100%success rate but...BACKGROUND Previous studies have validated the efficacy of both magnetic compression and surgical techniques in creating rabbit tracheoesophageal fistula(TEF)models.Magnetic compression achieves a 100%success rate but requires more time,while surgery,though less frequently successful,offers rapid model establishment and technical maturity in larger animal models.AIM To determine the optimal approach for rabbit disease modeling and refine the process.METHODS TEF models were created in 12 rabbits using both the modified magnetic compression technique and surgery.Comparisons of the time to model establishment,success rate,food and water intake,weight changes,activity levels,bronchoscopy findings,white blood cell counts,and biopsies were performed.In response to the failures encountered during modified magnetic compression modeling,we increased the sample size to 15 rabbit models and assessed the repeatability and stability of the models,comparing them with the original magnetic compression technique.RESULTS The modified magnetic compression technique achieved a 66.7%success rate,whereas the success rate of the surgery technique was 33.3%.Surviving surgical rabbits might not meet subsequent experimental requirements due to TEF-related inflammation.In the modified magnetic compression group,one rabbit died,possibly due to magnet corrosion,and another died from tracheal magnet obstruction.Similar events occurred during the second round of modified magnetic compression modeling,with one rabbit possibly succumbing to aggravated lung infection.The operation time of the first round of modified magnetic compression was 3.2±0.6 min,which was significantly reduced to 2.1±0.4 min in the second round,compared to both the first round and that of the original technique.CONCLUSION The modified magnetic compression technique exhibits lower stress responses,a simple procedure,a high success rate,and lower modeling costs,making it a more appropriate choice for constructing TEF models in rabbits.展开更多
A novel method for automatic ultra-precision alignment is presented.This method relies on the modified Moiré technique,and alignment marks are used in the form of gratings.The modified Moiré technique can ef...A novel method for automatic ultra-precision alignment is presented.This method relies on the modified Moiré technique,and alignment marks are used in the form of gratings.The modified Moiré technique can effectively improve detecting sensitivity of signals and simplify the control system by using only one pair of laser-Moiré sensors.We present the mathematical model and simulation results of diffracting two gratings.The effect of various parameters on Moiré signals is studied theoretically and experimentally,and the results are found to be consistent.A computer controlled alignment device using one pair of Moiré sensors is designed.The device can achieve a fully automatic precision alignment by the modified Moiré signal.The experimental result shows that the alignment device can obtain the resolution of 5 nm and the positioning accuracy of ±0 5 μm.展开更多
Based on the nonlinear failure criterion and the upper bound theorem, the modified tangential technique method was proposed to derive the expression of supporting pressure acting on shallow tunnel. Instead of the same...Based on the nonlinear failure criterion and the upper bound theorem, the modified tangential technique method was proposed to derive the expression of supporting pressure acting on shallow tunnel. Instead of the same stress state, different normal stresses on element boundaries were used. In order to investigate the influence of different factors on supporting pressures, the failure mechanism was established. The solution of supporting pressure, with different parameters, was obtained by optimization theory. The corresponding failure mechanism and numerical results were presented. In comparison with the results using the single tangential technique method, it is found that the proposed method is effective, and the good agreement shows that the present solution of supporting pressure is reliable.展开更多
In this paper, to investigate the influence of soil inhomogeneity on the bending of circular thinplates on elastic foundations, the static problem of circular thin plates on Gibson elasticfoundation is solved using an...In this paper, to investigate the influence of soil inhomogeneity on the bending of circular thinplates on elastic foundations, the static problem of circular thin plates on Gibson elasticfoundation is solved using an iterative method based on the modified Vlasov model. On the basisof the principle of minimum potential energy, the governing differential equations and boundaryconditions for circular thin plates on modified Vlasov foundation considering the characteristics ofGibson soil are derived. The equations for the attenuation parameter in bending problem are alsoobtained, and the issue of unknown parameters being difficult to determine is solved using theiterative method. Numerical examples are analyzed and the results are in good agreement withthose form other literatures. It proves that the method is practical and accurate. Theinhomogeneity of modified Vlasov foundations has some influence on the deformation andinternal force behavior of circular thin plates. The effects of various parameters on the bending ofcircular plates and characteristic parameters of the foundation are discussed. The modified modelfurther enriches and develops the elastic foundations. Relevant conclusions that are meaningful toengineering practice are drawn.展开更多
Over the years vaccination has proven to be the most successful health protection program for large populations,to prevent them from acquiring serious infectious and contagious diseases caused by exogenous antigens(ag...Over the years vaccination has proven to be the most successful health protection program for large populations,to prevent them from acquiring serious infectious and contagious diseases caused by exogenous antigens(ags) such as bacteria and viruses.Protection is generally achieved by an active immunization program,though passive immunization has also been employed, especially in the past,to combat diseases caused by certain bacterial infections(e.g.tetanus, diphtheria,etc.). Most recently,encouraging research data suggests that therapeutic approaches employing vaccination techniques can also be used to correct or deal with mishaps induced by or involving endogenous ags.However,most attempts at employing conventional vaccination techniques to do so have proven less than successful.In the case of cancer,one of the reasons for this is that the presentation of cancer related ags in presently available immunization frameworks is unable to evoke a powerful,specific cancer killing response.Therefore,drug treatments have been required in order to achieve additional beneficial effects. Recently,the Barabas group has developed a new vaccination technique(the third vaccination method,after active and passive immunization) called Modified Vaccination Technique(MVT). In experiments the MVT has been able to prevent-and with equal effectiveness,terminatemishaps induced by or involving endogenous ags,e.g.in an experimental autoimmune kidney disease called slowly progressive Heymann nephritis(SPHN). The MVT is safe,and is able to initiate a specific immune response in the injected host(provided the injected components are in pure form).The MVT promises to provide the next generation of vaccines for the prevention,treatment,and termination of chronic disorders in humans,such as autoimmune diseases,cancer,and chronic infections.展开更多
Objectives: In this study, we aimed to compare early results of the modified eversion carotid endarterectomy technique with the conventional carotid endarterectomy technique. The modified eversion carotid endarterecto...Objectives: In this study, we aimed to compare early results of the modified eversion carotid endarterectomy technique with the conventional carotid endarterectomy technique. The modified eversion carotid endarterectomy technique consisted of a longitudinal arteriotomy that was begun from the common carotid artery proximally to the origin of external carotid artery. We also avoided applying a carotid shunt during surgery in both techniques. Methods: Each patient was evaluated for coronary artery stenosis and valve replacement indications. Diagnosis of significant coronary artery stenosis or valve disease directed us to a combination of CEA and cardiac surgery (CABG/Valvular). We generally had a tendency to perform these two surgical procedures separately. Patients which had surgery for both at the same session were excluded in this study. As a result, our study included 120 patients and 137 carotid interventions. We performed the modified eversion carotid endarterectomy technique in 61 patients (68 carotid interventions) (Group A) and the conventional CEA technique in 59 patients (69 carotid interventions) (Group B). At follow-up, the patients were evaluated by physical examination and color Doppler USG. Results: There was no significant difference between the groups in terms of demographic data. Statistically significant difference was observed in one operative parameter between Group A and Group B;patchplasty requirements during surgery (12 carotid interventions in group B and 4 carotid interventions in group A, p = 0.036). We recorded temporary tongue deviation in five cases, facial asymmetry in eight cases, hoarseness in four cases, neurocognitive impairment in three cases and transient neurologic in two cases with no significant difference between the groups. There was in one case of permanent neurologic deficit (1 in group B). There were two postoperative deaths (1 in group A and 1 in group B). The death in group A occurred because of subarachnoid haemorrhage and the death in group B occurred because of myocardial infarction. After 6 month follow-up, no restenosis occurred in group A. Restenosis occurred in three patients of group B. Conclusion: The modified eversion technique for carotid endarterectomy decrease the incidence of patchplasty applications and postoperative restenosis by avoiding internal carotid artery manipulation and sewing. Besides, it is easy and possible to remove plaques completely from internal carotid artery via the modified arteriotomy line.展开更多
The purpose of this work is to find new soliton solutions of the complex Ginzburg–Landau equation(GLE)with Kerr law non-linearity.The considered equation is an imperative nonlinear partial differential equation(PDE)i...The purpose of this work is to find new soliton solutions of the complex Ginzburg–Landau equation(GLE)with Kerr law non-linearity.The considered equation is an imperative nonlinear partial differential equation(PDE)in the field of physics.The applications of complex GLE can be found in optics,plasma and other related fields.The modified extended tanh technique with Riccati equation is applied to solve the Complex GLE.The results are presented under a suitable choice for the values of parameters.Figures are shown using the three and two-dimensional plots to represent the shape of the solution in real,and imaginary parts in order to discuss the similarities and difference between them.The graphical representation of the results depicts the typical behavior of soliton solutions.The obtained soliton solutions are of different forms,such as,hyperbolic and trigonometric functions.The results presented in this paper are novel and reported first time in the literature.Simulation results establish the validity and applicability of the suggested technique for the complex GLE.The suggested method with symbolic computational software such as,Mathematica and Maple,is proven as an effective way to acquire the soliton solutions of nonlinear partial differential equations(PDEs)as well as complex PDEs.展开更多
A novel chedrically-modified electrode containing 1:12 phosphomolybdic anions wasachieved on the surface of platinum electrode by the sol-gel technique. The electrode exhibits ahigh catalytic activity towards the elec...A novel chedrically-modified electrode containing 1:12 phosphomolybdic anions wasachieved on the surface of platinum electrode by the sol-gel technique. The electrode exhibits ahigh catalytic activity towards the electroreduction of BrO3- anions.展开更多
Objective:To investigate the clinical effect of modified closed negative pressure suction technique combined with flap transplantation on the treatment of deep chronic refractory wounds.Methods:During March of 2015 to...Objective:To investigate the clinical effect of modified closed negative pressure suction technique combined with flap transplantation on the treatment of deep chronic refractory wounds.Methods:During March of 2015 to April of 2018,52 cases of patients with deep chronic refractory wounds were selected as research objects.They were divided into the control group and the treatment group by use of the random number table method,with 26 cases in each group.Among them,the control group was given conventional debridement combined with flap reconstruction,and the treatment group was treated with modified closed negative pressure suction technique combined with flap transplantation to observe the clinical effect.Results:(1)According to the analysis on the effect of flap transplantation,the excellent and good rate of the treatment group was 92.3%,and in the control group,it was 76.9%(p<0.05).(2)According to the statistics,the incidence of complications in the treatment group was lower than that in the control group(p<0.05).Conclusions:Modified closed negative pressure suction technique combined with flap transplantation has a good effect on the treatment of deep chronic refractory wounds with fewer complications.展开更多
Objective To investigate the operation key points,instrument improvement and shortterm effects in total en bloc spondylectomy (TES) via a single posterior approach for thoracic and lumbar tumors.Methods A series of mo...Objective To investigate the operation key points,instrument improvement and shortterm effects in total en bloc spondylectomy (TES) via a single posterior approach for thoracic and lumbar tumors.Methods A series of modified展开更多
Objective To summarize the clinical study of modified total aortic arch replacement and stent elephant trunk technique treatment to patients with DeBakey Ⅰ thoracic aortic dissection. Methods From January 2006 to Oct...Objective To summarize the clinical study of modified total aortic arch replacement and stent elephant trunk technique treatment to patients with DeBakey Ⅰ thoracic aortic dissection. Methods From January 2006 to October 2010,101 cases of DeBakeyⅠaortic dissection were treated by modified total arch replacement and stent elephant trunk technique,in which emergencey surgery were performed on 73 cases. There were 76 male and 25展开更多
Objective To investigate the effect of a modified technique for reparing secondary unilateral cleft nasal deformity. Methods Nasal alar cartilage was explosed through dish - like incision,and base of naris was cut to ...Objective To investigate the effect of a modified technique for reparing secondary unilateral cleft nasal deformity. Methods Nasal alar cartilage was explosed through dish - like incision,and base of naris was cut to loosening and replacing the orbicularis oris,releasing展开更多
A nano-displacement measurement system with duo-gratings is analyzed by using optics theory,a math- ematic model for the system is established,and the characteristic of laser Moirésignals is studied through CAD s...A nano-displacement measurement system with duo-gratings is analyzed by using optics theory,a math- ematic model for the system is established,and the characteristic of laser Moirésignals is studied through CAD simu- lation.To improve signal sensitivity and positioning accuracy,two methods of precision positioning are brought for- ward:differential Moirépositioning method and modified Moirépositioning method.A compound control system for precision positioning is set up by combining these 2 Moiréalignment methods,in which the modified Moiréalignment technique is used for coarse alignment and the differential Moiréalignment technique is used for fine alignment,and the system obtains positioning accuracy of±10 nm in±500μm positioning range with shot response time.展开更多
Multi<span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">objective optimization problem (MOOP) is an important class of optimization problem that ensures...Multi<span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">objective optimization problem (MOOP) is an important class of optimization problem that ensures users </span><span style="font-family:Verdana;">to </span><span style="font-family:Verdana;">model a large variety of real world applications. In this paper an advanced transformation technique has been proposed to solve MOOP. An algorithm is suggested and the computer application of algorithm has </span><span style="font-family:Verdana;">been </span><span style="font-family:Verdana;">demonstrated by a flow chart. This method is comparatively easy to calculate. Applying on different types of examples, the result indicate</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> that the proposed method gives better solution than other methods and it is less time consuming. Physical presentation and data analysis represent the worth of the method more compactly.</span>展开更多
In this paper, the problem of optimum allocation of repairable and replaceable components in a system is formulated as a Bi-objective stochastic non linear programming problem. The system maintenance time and cost are...In this paper, the problem of optimum allocation of repairable and replaceable components in a system is formulated as a Bi-objective stochastic non linear programming problem. The system maintenance time and cost are random variable and has gamma and normal distribution respectively. A Bi-criteria optimization technique, weighted Tchebycheff is used to obtain the optimum allocation for a system. A numerical example is also presented to illustrate the computational details.展开更多
Applications of certain multi-parameter acceleration techniques used with themodified New-ton-Raphson (mN-R) methods to solve the nonlinear equations arising from rigid-plasticfinite element analysis are investigated....Applications of certain multi-parameter acceleration techniques used with themodified New-ton-Raphson (mN-R) methods to solve the nonlinear equations arising from rigid-plasticfinite element analysis are investigated. New modified multi-parameter techniques, developed fromCrisfield's multi-parameter methods, are utilized to solve these nonlinear equations. The numericalperformance of these techniques is compared with the standard Newton-Raphson method (sN-R),Crisfield's single parameter method (C1), Crisfield's two parameter method (C2) and Crisfield'sthree parameter method (C3). The new techniques do not involve additional residual force calculationand require little extra computational effort. In addition, they are more robust and efficient thanother existing acceleration techniques.展开更多
For many years,surgical treatment of buried penis in children has been researched by several scholars,and numerous methods exist.This study aimed to explore the clinical effect of a modified fixation technique in trea...For many years,surgical treatment of buried penis in children has been researched by several scholars,and numerous methods exist.This study aimed to explore the clinical effect of a modified fixation technique in treating buried penis in children.Clinical data of 94 patients with buried penis who were treated using the modified penile fixation technique from March 2017 to February 2019 in Fujian Maternity and Child Health Hospital(Fuzhou,China)were retrospectively collected,compared,and analyzed.Clinical data of 107 patients with buried penis who were treated using traditional penile fixation technique from February 2014 to February 2017 were chosen for comparison.The results showed that at 6 months and 12 months after surgery,the penile lengths in the modified penile fixation group were longer than those in the traditional penile fixation group(both P<0.05).The incidence of postoperative skin contracture and penile retraction in the modified penile fixation group was less than that in the traditional penile fixation group(P=0.034 and P=0.012,respectively).When the two groups were compared in terms of parents'satisfaction scores,the scores for penile size,penile morphology,and voiding status in the modified penile fixation group were higher than those in the traditional penile fixation group at 2-week,6-month,and 12-month follow-ups after surgery(all P<0.05).We concluded that the modified penile fixation technique could effectively reduce the incidence of skin contracture and penile retraction and improve the penile length and satisfaction of patients'parents.展开更多
In order to reduce both the weight of vehicles and the damage of occupants in a crash event simultaneously, it is necessary to perform a multi-objective optimal design of the automotive energy absorbing components. Mo...In order to reduce both the weight of vehicles and the damage of occupants in a crash event simultaneously, it is necessary to perform a multi-objective optimal design of the automotive energy absorbing components. Modified non-dominated sorting genetic algorithm II(NSGA II) was used for multi-objective optimization of automotive S-rail considering absorbed energy(E), peak crushing force(Fmax) and mass of the structure(W) as three conflicting objective functions. In the multi-objective optimization problem(MOP), E and Fmax are defined by polynomial models extracted using the software GEvo M based on train and test data obtained from numerical simulation of quasi-static crushing of the S-rail using ABAQUS. Finally, the nearest to ideal point(NIP)method and technique for ordering preferences by similarity to ideal solution(TOPSIS) method are used to find the some trade-off optimum design points from all non-dominated optimum design points represented by the Pareto fronts. Results represent that the optimum design point obtained from TOPSIS method exhibits better trade-off in comparison with that of optimum design point obtained from NIP method.展开更多
文摘This study develops an Enhanced Threshold Based Energy Detection approach(ETBED)for spectrum sensing in a cognitive radio network.The threshold identification method is implemented in the received signal at the secondary user based on the square law.The proposed method is implemented with the signal transmission of multiple outputs-orthogonal frequency division multiplexing.Additionally,the proposed method is considered the dynamic detection threshold adjustments and energy identification spectrum sensing technique in cognitive radio systems.In the dynamic threshold,the signal ratio-based threshold is fixed.The threshold is computed by considering the Modified Black Widow Optimization Algorithm(MBWO).So,the proposed methodology is a combination of dynamic threshold detection and MBWO.The general threshold-based detection technique has different limitations such as the inability optimal signal threshold for determining the presence of the primary user signal.These limitations undermine the sensing accuracy of the energy identification technique.Hence,the ETBED technique is developed to enhance the energy efficiency of cognitive radio networks.The projected approach is executed and analyzed with performance and comparison analysis.The proposed method is contrasted with the conventional techniques of theWhale Optimization Algorithm(WOA)and GreyWolf Optimization(GWO).It indicated superior results,achieving a high average throughput of 2.2 Mbps and an energy efficiency of 3.8,outperforming conventional techniques.
基金Independent Scientific Research Project for Graduate Students of Beijing University of Chinese Medicine(2023),No.ZJKT2023020.
文摘BACKGROUND Previous studies have validated the efficacy of both magnetic compression and surgical techniques in creating rabbit tracheoesophageal fistula(TEF)models.Magnetic compression achieves a 100%success rate but requires more time,while surgery,though less frequently successful,offers rapid model establishment and technical maturity in larger animal models.AIM To determine the optimal approach for rabbit disease modeling and refine the process.METHODS TEF models were created in 12 rabbits using both the modified magnetic compression technique and surgery.Comparisons of the time to model establishment,success rate,food and water intake,weight changes,activity levels,bronchoscopy findings,white blood cell counts,and biopsies were performed.In response to the failures encountered during modified magnetic compression modeling,we increased the sample size to 15 rabbit models and assessed the repeatability and stability of the models,comparing them with the original magnetic compression technique.RESULTS The modified magnetic compression technique achieved a 66.7%success rate,whereas the success rate of the surgery technique was 33.3%.Surviving surgical rabbits might not meet subsequent experimental requirements due to TEF-related inflammation.In the modified magnetic compression group,one rabbit died,possibly due to magnet corrosion,and another died from tracheal magnet obstruction.Similar events occurred during the second round of modified magnetic compression modeling,with one rabbit possibly succumbing to aggravated lung infection.The operation time of the first round of modified magnetic compression was 3.2±0.6 min,which was significantly reduced to 2.1±0.4 min in the second round,compared to both the first round and that of the original technique.CONCLUSION The modified magnetic compression technique exhibits lower stress responses,a simple procedure,a high success rate,and lower modeling costs,making it a more appropriate choice for constructing TEF models in rabbits.
文摘A novel method for automatic ultra-precision alignment is presented.This method relies on the modified Moiré technique,and alignment marks are used in the form of gratings.The modified Moiré technique can effectively improve detecting sensitivity of signals and simplify the control system by using only one pair of laser-Moiré sensors.We present the mathematical model and simulation results of diffracting two gratings.The effect of various parameters on Moiré signals is studied theoretically and experimentally,and the results are found to be consistent.A computer controlled alignment device using one pair of Moiré sensors is designed.The device can achieve a fully automatic precision alignment by the modified Moiré signal.The experimental result shows that the alignment device can obtain the resolution of 5 nm and the positioning accuracy of ±0 5 μm.
基金Projects(2013CB0360042011CB013800)supported by the National Basic Research Program of China+1 种基金Project(51178468)supported by the National Natural Science Foundation of ChinaProject(2011G013-B)supported by the Science and Technology Development of Railways Department in China
文摘Based on the nonlinear failure criterion and the upper bound theorem, the modified tangential technique method was proposed to derive the expression of supporting pressure acting on shallow tunnel. Instead of the same stress state, different normal stresses on element boundaries were used. In order to investigate the influence of different factors on supporting pressures, the failure mechanism was established. The solution of supporting pressure, with different parameters, was obtained by optimization theory. The corresponding failure mechanism and numerical results were presented. In comparison with the results using the single tangential technique method, it is found that the proposed method is effective, and the good agreement shows that the present solution of supporting pressure is reliable.
基金financially supported by the National Natural Science Foundation of China (Grant 51278420)the Natural Science Foundation of Shaanxi Province (Grant 2017JM5021)
文摘In this paper, to investigate the influence of soil inhomogeneity on the bending of circular thinplates on elastic foundations, the static problem of circular thin plates on Gibson elasticfoundation is solved using an iterative method based on the modified Vlasov model. On the basisof the principle of minimum potential energy, the governing differential equations and boundaryconditions for circular thin plates on modified Vlasov foundation considering the characteristics ofGibson soil are derived. The equations for the attenuation parameter in bending problem are alsoobtained, and the issue of unknown parameters being difficult to determine is solved using theiterative method. Numerical examples are analyzed and the results are in good agreement withthose form other literatures. It proves that the method is practical and accurate. Theinhomogeneity of modified Vlasov foundations has some influence on the deformation andinternal force behavior of circular thin plates. The effects of various parameters on the bending ofcircular plates and characteristic parameters of the foundation are discussed. The modified modelfurther enriches and develops the elastic foundations. Relevant conclusions that are meaningful toengineering practice are drawn.
文摘Over the years vaccination has proven to be the most successful health protection program for large populations,to prevent them from acquiring serious infectious and contagious diseases caused by exogenous antigens(ags) such as bacteria and viruses.Protection is generally achieved by an active immunization program,though passive immunization has also been employed, especially in the past,to combat diseases caused by certain bacterial infections(e.g.tetanus, diphtheria,etc.). Most recently,encouraging research data suggests that therapeutic approaches employing vaccination techniques can also be used to correct or deal with mishaps induced by or involving endogenous ags.However,most attempts at employing conventional vaccination techniques to do so have proven less than successful.In the case of cancer,one of the reasons for this is that the presentation of cancer related ags in presently available immunization frameworks is unable to evoke a powerful,specific cancer killing response.Therefore,drug treatments have been required in order to achieve additional beneficial effects. Recently,the Barabas group has developed a new vaccination technique(the third vaccination method,after active and passive immunization) called Modified Vaccination Technique(MVT). In experiments the MVT has been able to prevent-and with equal effectiveness,terminatemishaps induced by or involving endogenous ags,e.g.in an experimental autoimmune kidney disease called slowly progressive Heymann nephritis(SPHN). The MVT is safe,and is able to initiate a specific immune response in the injected host(provided the injected components are in pure form).The MVT promises to provide the next generation of vaccines for the prevention,treatment,and termination of chronic disorders in humans,such as autoimmune diseases,cancer,and chronic infections.
文摘Objectives: In this study, we aimed to compare early results of the modified eversion carotid endarterectomy technique with the conventional carotid endarterectomy technique. The modified eversion carotid endarterectomy technique consisted of a longitudinal arteriotomy that was begun from the common carotid artery proximally to the origin of external carotid artery. We also avoided applying a carotid shunt during surgery in both techniques. Methods: Each patient was evaluated for coronary artery stenosis and valve replacement indications. Diagnosis of significant coronary artery stenosis or valve disease directed us to a combination of CEA and cardiac surgery (CABG/Valvular). We generally had a tendency to perform these two surgical procedures separately. Patients which had surgery for both at the same session were excluded in this study. As a result, our study included 120 patients and 137 carotid interventions. We performed the modified eversion carotid endarterectomy technique in 61 patients (68 carotid interventions) (Group A) and the conventional CEA technique in 59 patients (69 carotid interventions) (Group B). At follow-up, the patients were evaluated by physical examination and color Doppler USG. Results: There was no significant difference between the groups in terms of demographic data. Statistically significant difference was observed in one operative parameter between Group A and Group B;patchplasty requirements during surgery (12 carotid interventions in group B and 4 carotid interventions in group A, p = 0.036). We recorded temporary tongue deviation in five cases, facial asymmetry in eight cases, hoarseness in four cases, neurocognitive impairment in three cases and transient neurologic in two cases with no significant difference between the groups. There was in one case of permanent neurologic deficit (1 in group B). There were two postoperative deaths (1 in group A and 1 in group B). The death in group A occurred because of subarachnoid haemorrhage and the death in group B occurred because of myocardial infarction. After 6 month follow-up, no restenosis occurred in group A. Restenosis occurred in three patients of group B. Conclusion: The modified eversion technique for carotid endarterectomy decrease the incidence of patchplasty applications and postoperative restenosis by avoiding internal carotid artery manipulation and sewing. Besides, it is easy and possible to remove plaques completely from internal carotid artery via the modified arteriotomy line.
基金the National Natural Science Foundation of China(Grant Nos.11971142,11871202,61673169,11701176,11626101,11601485).YMC received the grant for this work.
文摘The purpose of this work is to find new soliton solutions of the complex Ginzburg–Landau equation(GLE)with Kerr law non-linearity.The considered equation is an imperative nonlinear partial differential equation(PDE)in the field of physics.The applications of complex GLE can be found in optics,plasma and other related fields.The modified extended tanh technique with Riccati equation is applied to solve the Complex GLE.The results are presented under a suitable choice for the values of parameters.Figures are shown using the three and two-dimensional plots to represent the shape of the solution in real,and imaginary parts in order to discuss the similarities and difference between them.The graphical representation of the results depicts the typical behavior of soliton solutions.The obtained soliton solutions are of different forms,such as,hyperbolic and trigonometric functions.The results presented in this paper are novel and reported first time in the literature.Simulation results establish the validity and applicability of the suggested technique for the complex GLE.The suggested method with symbolic computational software such as,Mathematica and Maple,is proven as an effective way to acquire the soliton solutions of nonlinear partial differential equations(PDEs)as well as complex PDEs.
文摘A novel chedrically-modified electrode containing 1:12 phosphomolybdic anions wasachieved on the surface of platinum electrode by the sol-gel technique. The electrode exhibits ahigh catalytic activity towards the electroreduction of BrO3- anions.
文摘Objective:To investigate the clinical effect of modified closed negative pressure suction technique combined with flap transplantation on the treatment of deep chronic refractory wounds.Methods:During March of 2015 to April of 2018,52 cases of patients with deep chronic refractory wounds were selected as research objects.They were divided into the control group and the treatment group by use of the random number table method,with 26 cases in each group.Among them,the control group was given conventional debridement combined with flap reconstruction,and the treatment group was treated with modified closed negative pressure suction technique combined with flap transplantation to observe the clinical effect.Results:(1)According to the analysis on the effect of flap transplantation,the excellent and good rate of the treatment group was 92.3%,and in the control group,it was 76.9%(p<0.05).(2)According to the statistics,the incidence of complications in the treatment group was lower than that in the control group(p<0.05).Conclusions:Modified closed negative pressure suction technique combined with flap transplantation has a good effect on the treatment of deep chronic refractory wounds with fewer complications.
文摘Objective To investigate the operation key points,instrument improvement and shortterm effects in total en bloc spondylectomy (TES) via a single posterior approach for thoracic and lumbar tumors.Methods A series of modified
文摘Objective To summarize the clinical study of modified total aortic arch replacement and stent elephant trunk technique treatment to patients with DeBakey Ⅰ thoracic aortic dissection. Methods From January 2006 to October 2010,101 cases of DeBakeyⅠaortic dissection were treated by modified total arch replacement and stent elephant trunk technique,in which emergencey surgery were performed on 73 cases. There were 76 male and 25
文摘Objective To investigate the effect of a modified technique for reparing secondary unilateral cleft nasal deformity. Methods Nasal alar cartilage was explosed through dish - like incision,and base of naris was cut to loosening and replacing the orbicularis oris,releasing
基金Supported by the National High Technology Research and Development Program of China(863 Program)(2005AA303610)
文摘A nano-displacement measurement system with duo-gratings is analyzed by using optics theory,a math- ematic model for the system is established,and the characteristic of laser Moirésignals is studied through CAD simu- lation.To improve signal sensitivity and positioning accuracy,two methods of precision positioning are brought for- ward:differential Moirépositioning method and modified Moirépositioning method.A compound control system for precision positioning is set up by combining these 2 Moiréalignment methods,in which the modified Moiréalignment technique is used for coarse alignment and the differential Moiréalignment technique is used for fine alignment,and the system obtains positioning accuracy of±10 nm in±500μm positioning range with shot response time.
文摘Multi<span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">objective optimization problem (MOOP) is an important class of optimization problem that ensures users </span><span style="font-family:Verdana;">to </span><span style="font-family:Verdana;">model a large variety of real world applications. In this paper an advanced transformation technique has been proposed to solve MOOP. An algorithm is suggested and the computer application of algorithm has </span><span style="font-family:Verdana;">been </span><span style="font-family:Verdana;">demonstrated by a flow chart. This method is comparatively easy to calculate. Applying on different types of examples, the result indicate</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> that the proposed method gives better solution than other methods and it is less time consuming. Physical presentation and data analysis represent the worth of the method more compactly.</span>
文摘In this paper, the problem of optimum allocation of repairable and replaceable components in a system is formulated as a Bi-objective stochastic non linear programming problem. The system maintenance time and cost are random variable and has gamma and normal distribution respectively. A Bi-criteria optimization technique, weighted Tchebycheff is used to obtain the optimum allocation for a system. A numerical example is also presented to illustrate the computational details.
文摘Applications of certain multi-parameter acceleration techniques used with themodified New-ton-Raphson (mN-R) methods to solve the nonlinear equations arising from rigid-plasticfinite element analysis are investigated. New modified multi-parameter techniques, developed fromCrisfield's multi-parameter methods, are utilized to solve these nonlinear equations. The numericalperformance of these techniques is compared with the standard Newton-Raphson method (sN-R),Crisfield's single parameter method (C1), Crisfield's two parameter method (C2) and Crisfield'sthree parameter method (C3). The new techniques do not involve additional residual force calculationand require little extra computational effort. In addition, they are more robust and efficient thanother existing acceleration techniques.
文摘For many years,surgical treatment of buried penis in children has been researched by several scholars,and numerous methods exist.This study aimed to explore the clinical effect of a modified fixation technique in treating buried penis in children.Clinical data of 94 patients with buried penis who were treated using the modified penile fixation technique from March 2017 to February 2019 in Fujian Maternity and Child Health Hospital(Fuzhou,China)were retrospectively collected,compared,and analyzed.Clinical data of 107 patients with buried penis who were treated using traditional penile fixation technique from February 2014 to February 2017 were chosen for comparison.The results showed that at 6 months and 12 months after surgery,the penile lengths in the modified penile fixation group were longer than those in the traditional penile fixation group(both P<0.05).The incidence of postoperative skin contracture and penile retraction in the modified penile fixation group was less than that in the traditional penile fixation group(P=0.034 and P=0.012,respectively).When the two groups were compared in terms of parents'satisfaction scores,the scores for penile size,penile morphology,and voiding status in the modified penile fixation group were higher than those in the traditional penile fixation group at 2-week,6-month,and 12-month follow-ups after surgery(all P<0.05).We concluded that the modified penile fixation technique could effectively reduce the incidence of skin contracture and penile retraction and improve the penile length and satisfaction of patients'parents.
文摘In order to reduce both the weight of vehicles and the damage of occupants in a crash event simultaneously, it is necessary to perform a multi-objective optimal design of the automotive energy absorbing components. Modified non-dominated sorting genetic algorithm II(NSGA II) was used for multi-objective optimization of automotive S-rail considering absorbed energy(E), peak crushing force(Fmax) and mass of the structure(W) as three conflicting objective functions. In the multi-objective optimization problem(MOP), E and Fmax are defined by polynomial models extracted using the software GEvo M based on train and test data obtained from numerical simulation of quasi-static crushing of the S-rail using ABAQUS. Finally, the nearest to ideal point(NIP)method and technique for ordering preferences by similarity to ideal solution(TOPSIS) method are used to find the some trade-off optimum design points from all non-dominated optimum design points represented by the Pareto fronts. Results represent that the optimum design point obtained from TOPSIS method exhibits better trade-off in comparison with that of optimum design point obtained from NIP method.