A new biomimetic bulk acoustic wave sensor based on molecularly imprinted microspheres (MUM) technique was described. The sensing materials were synthesized by precipitation polymerization. By using the Scatchard anal...A new biomimetic bulk acoustic wave sensor based on molecularly imprinted microspheres (MUM) technique was described. The sensing materials were synthesized by precipitation polymerization. By using the Scatchard analysis, the equilibrium dissociation constant K-D and the apparent maximum number Q(max) of the binding sites were calculated to be 3.70 mmol (.) L-1 and 9.11 mumol (.) g(-1), respectively. The sensor exhibited a sensitive response to the template compound (dipyridamole) in liquid phase with a detection Unfit of 2 x 10(-9) mol (.) L-1. The recoveries of the sensor were 95.1%-105.4%. Studies presented in this paper show that the stability of this sensor is excellent. The sensor has been applied successfully to the determination of dipyridamole in human urine.展开更多
文摘A new biomimetic bulk acoustic wave sensor based on molecularly imprinted microspheres (MUM) technique was described. The sensing materials were synthesized by precipitation polymerization. By using the Scatchard analysis, the equilibrium dissociation constant K-D and the apparent maximum number Q(max) of the binding sites were calculated to be 3.70 mmol (.) L-1 and 9.11 mumol (.) g(-1), respectively. The sensor exhibited a sensitive response to the template compound (dipyridamole) in liquid phase with a detection Unfit of 2 x 10(-9) mol (.) L-1. The recoveries of the sensor were 95.1%-105.4%. Studies presented in this paper show that the stability of this sensor is excellent. The sensor has been applied successfully to the determination of dipyridamole in human urine.
基金Project of Chinese Nature Science Foundation(21205054)Applied Basic Research Program of Yunnan Provincial Science and Technology Department(2011FZ043)College Students Science and Technology Innovation Project of Kunming University of Science and Technology(20131125111021)
