At the Plant of Production of Radioisotopes part of Nuclear Center of Mexico （ININ）, weekly radiofarmaceutics of sodium iodohippurate and meta-iodobenzyl-guanidine are prepared, these compounds are known as marked m...At the Plant of Production of Radioisotopes part of Nuclear Center of Mexico （ININ）, weekly radiofarmaceutics of sodium iodohippurate and meta-iodobenzyl-guanidine are prepared, these compounds are known as marked molecules with iodine-131. Currently the processes for the preparation of these compounds are carried out individually and in manual form, in box of gloves, presenting radiological risks. To avoid these risks, this work, shows equipment that is inside a warm cell with the finality of minimizing the radiological risks. Also, this semi-automated equipment has the purpose of to reduce the radiation exposure of personnel involved in the process of marking molecules. The routine industrial production with this equipment starts with the preparation of 9 marked doses of sodium iodohippurate of 2.73 mCi of iodine-131, each of the vials with saline solution of 4.5 mL and the product that containing the marked molecules of 0.5 mL with a percentage of marked of 95.6%. The innovation of this work consists in presenting a new design of equipment, for marked molecules, formed by electrical, mechanical, vacuum systems, and air extraction system.展开更多
文摘At the Plant of Production of Radioisotopes part of Nuclear Center of Mexico （ININ）, weekly radiofarmaceutics of sodium iodohippurate and meta-iodobenzyl-guanidine are prepared, these compounds are known as marked molecules with iodine-131. Currently the processes for the preparation of these compounds are carried out individually and in manual form, in box of gloves, presenting radiological risks. To avoid these risks, this work, shows equipment that is inside a warm cell with the finality of minimizing the radiological risks. Also, this semi-automated equipment has the purpose of to reduce the radiation exposure of personnel involved in the process of marking molecules. The routine industrial production with this equipment starts with the preparation of 9 marked doses of sodium iodohippurate of 2.73 mCi of iodine-131, each of the vials with saline solution of 4.5 mL and the product that containing the marked molecules of 0.5 mL with a percentage of marked of 95.6%. The innovation of this work consists in presenting a new design of equipment, for marked molecules, formed by electrical, mechanical, vacuum systems, and air extraction system.
