Application of molybdenum target X-ray photography in imaging analysis of caudal intervertebral disc degeneration in rats

BACKGROUND Conventional plain X-ray images of rats,the most common animals used as degeneration models,exhibit unclear vertebral structure and blurry intervertebral disc spaces due to their small size,slender vertebral bodies.AIM To apply molybdenum target X-ray photography in the evaluation of caudal intervertebral disc(IVD)degeneration in rat models.METHODS Two types of rat caudal IVD degeneration models(needle-punctured model and endplate-destructed model)were established,and their effectiveness was verified using nuclear magnetic resonance imaging.Molybdenum target inspection and routine plain X-ray were then performed on these models.Additionally,four observers were assigned to measure the intervertebral height of degenerated segments on molybdenum target plain X-ray images and routine plain X-ray images,respectively.The degeneration was evaluated and statistical analysis was subsequently conducted.RESULTS Nine rats in the needle-punctured model and 10 rats in the endplate-destructed model were effective.Compared with routine plain X-ray images,molybdenum target plain X-ray images showed higher clarity,stronger contrast,as well as clearer and more accurate structural development.The McNemar test confirmed that the difference was statistically significant(P=0.031).In the two models,the reliability of the intervertebral height measured by the four observers on routine plain X-ray images was poor(ICC<0.4),while the data obtained from the molybdenum target plain X-ray images were more reliable.CONCLUSIONMolybdenum target inspection can obtain clearer images and display fine calcification in the imaging evaluation of caudal IVD degeneration in rats,thus ensuring a more accurate evaluation of degeneration.

乳腺癌新辅助化疗前后X线征象的变化及意义

目的:对乳腺癌新辅助化疗(NCT)前后各种钼靶X线征象进行观察分析,以评价其疗效。方法:对比分析47例乳腺癌NCT前后钼靶摄影各主要征象的变化。结果:肿块变化发生率89.3%(42/47),其中类圆形肿块变化87.5%(7/8)、形态变化趋向不规则;模糊肿块93.7%(15/16)肿块边缘趋于清晰;肿块周围毛刺90.5%(19/21)变短甚至消失;透亮环肿块(1/2)可见瘤性实体缩小;病灶钙化74.2%(23/31)出现范围、数目、分布上的变化。结论:乳腺癌NCT前后钼靶摄影各种X线征象均有所变化。

乳腺导管内癌患者高频彩色多普勒超声与X线摄片检查早期诊断价值比较

【目的】比较导管内癌患者高频彩色多普勒超声与X线摄片检查的影像学征象及早期诊断价值。【方法】收集湖州市中心医院55例经手术和病理结果证实为导管内癌患者的临床资料,回顾性分析其影像学资料,包括高频彩色多普勒超声与X线摄片检查,比较两种影像学方法导管内癌影像学征象及其早期诊断价值。【结果】55例患者中,经高频彩色多普勒超声检查具有导管内癌表现28例,诊断准确率为50.9%;经X线摄片检查具有导管内癌表现39例,诊断准确率为70.9%。经统计结果显示,经X线摄片检查对导管内癌诊断准确率较高频彩色多普勒超声检查明显升高(P=0.049)。X线摄片检查诊断肿瘤微钙化的准确率为67.3%,较彩超检查的47.3%明显升高(P=0.034)。结合彩超与X线摄片诊断为导管内癌共43例,诊断准确率明显提高,为78.2%。【结论】乳腺X线摄片对导管内癌的早期诊断价值明显优于高频彩色多普勒超声检查,临床中可联合这两种影像学检查方法以起到优势互补、取长补短的作用,有助于提高对导管内癌的诊断准确率,降低漏诊率。

乳腺癌的临床体征和乳腺钼靶分析

目的通过比较乳腺癌乳腺钼钯检查和临床扪诊的各自特点，提高乳腺癌的诊断水平。方法回顾分析2002～2006年我院常规体检且经手术和病理穿刺证实为乳腺癌的28例患者，比较及分析临床扪诊与乳腺X线检查病变特征。结果28例乳腺癌患者，24例临床扪及包块，乳腺X线检查28例均有恶性征象，其中4例仅见钙化。结论乳腺X线检查优于临床扪诊，临床扪诊也是配合乳腺X线检查的重要步骤。

乳腺癌的钼靶X线诊断

目的：探讨乳腺癌的钼靶X线的表现特征，提高钼靶X线直接征象与间接征象对乳腺癌诊断的准确性。方法：鳍舍文献回顾分析我院87例经手术病理证实的乳腺癌的钼靶X线表现。结果：87例均为单侧发病，凭直接征象或直接征象加间接征象诊断乳腺癌71例。仅凭间接征象诊断乳腺癌7例，还有9例误诊。结论：钼靶X线摄影是诊断乳腺癌的常用方法，显示乳腺癌的直接和间接征象，结合临床一般可以做出正确诊断。