Although several surgical procedures exist for treating cubital tunnel syndrome, the best surgical option remains controversial. To evaluate the efficacy of anterior subcutaneous transposition of the ulnar nerve in pa...Although several surgical procedures exist for treating cubital tunnel syndrome, the best surgical option remains controversial. To evaluate the efficacy of anterior subcutaneous transposition of the ulnar nerve in patients with moderate to severe cubital tunnel syndrome and to analyze prognostic factors, we retrospectively reviewed 62 patients（65 elbows） diagnosed with cubital tunnel syndrome who underwent anterior subcutaneous transposition. Preoperatively, the initial severity of the disease was evaluated using the Mc Gowan scale as modified by Goldberg： 18 patients（28%） had grade IIA neuropathy, 20（31%） had grade IIB, and 27（42%） had grade III. Postoperatively, according to the Wilson ＆ Krout criteria, treatment outcomes were excellent in 38 patients（58%）, good in 16（25%）, fair in 7（11%）, and poor in 4（6%）, with an excellent and good rate of 83%. A negative correlation was found between the preoperative Mc Gowan grade and the postoperative Wilson ＆ Krout score. The patients having fair and poor treatment outcomes had more advanced age, lower nerve conduction velocity, and lower action potential amplitude compared with those having excellent and good treatment outcomes. These results suggest that anterior subcutaneous transposition of the ulnar nerve is effective and safe for the treatment of moderate to severe cubital tunnel syndrome, and initial severity, advancing age, and electrophysiological parameters can affect treatment outcome.展开更多
Objective： To explore the effect of electro-acupuncture and musk injection on recovery of injured sciatic nerve function in rats, so as to provide the experimental evidences for the promotion of peripheral nerve rege...Objective： To explore the effect of electro-acupuncture and musk injection on recovery of injured sciatic nerve function in rats, so as to provide the experimental evidences for the promotion of peripheral nerve regeneration by electro-acupuncture and musk injection. Methods： Following establishing rat model of sciatic nerve injury by operation, the rats were randomly divided into electro-acupuncture group, musk injection group, electro-acupuncture plus musk injection group and model group, then sciatic functional index （SFI） and motor nerve conduction velocity （MNCV） were measured after 4 weeks of treatment, 8 weeks of treatment and 12 weeks of treatment respectively to evaluate recovery of nerve function. Results： SFI and MNCV in electro-acupuncture group, musk injection group and electro-acupuncture plus musk injection group were improved more obviously than that in model group, with significant differences（P〈0.01, P〈0.05）. Conclusions： Both electro-acupuncture and musk injection could promote recovery of injured nerve function, and they had a certain synergetic effect and might be the effective methods in promoting recovery of injured peripheral nerve function.展开更多
目的系统评价针灸治疗2型糖尿病周围神经病变(DPN)对腓神经神经传导速度的影响,为针灸治疗DPN提供临床参考。方法通过检索中国生物力学文献数据库(CBM)、中国期刊全文数据库(CNKI)、维普期刊数据库(VIP)、万方数据库、Pub Med、Springer...目的系统评价针灸治疗2型糖尿病周围神经病变(DPN)对腓神经神经传导速度的影响,为针灸治疗DPN提供临床参考。方法通过检索中国生物力学文献数据库(CBM)、中国期刊全文数据库(CNKI)、维普期刊数据库(VIP)、万方数据库、Pub Med、Springer、Medline数据库,收集2000年1月至2014年1月关于针灸治疗2型DPN的随机对照试验(RCT),提取腓神经传导速度相关资料并进行方法学质量评价,采用Rev Man 5.1软件进行Meta分析。结果共纳入10个随机对照试验,合计685例患者,其中治疗组355例,对照组330例。Meta分析结果显示,针灸治疗2型DPN在提高腓神经运动神经传导速度(MNCV)和感觉神经传导速度(SNCV)方面可能优于对照组,差异均有统计学意义[MD=3.55,95%CI(0.79,6.31);MD=4.10,95%CI(0.22,7.99)]。结论针灸治疗2型DPN可以改善腓神经传导速度,值得临床应用。但由于本系统评价纳入研究较少,样本量小,且质量不高,存在偏倚的高度可能性,因此上述结论尚需要高质量、大样本、多中心的随机对照试验加以证实。展开更多
基金supported by grants from the National Program on Key Basic Research Project of China(973 Program),No.2014CB542200a grant from Innovation Program of Ministry of Education,No.IRT1201+1 种基金the National Natural Science Foundation of China,No.31271284,31171150,81171146,30971526,31100860,31040043,31371210Program for New Century Excellent Talents in University of Ministry of Education of China,No.BMU20110270
文摘Although several surgical procedures exist for treating cubital tunnel syndrome, the best surgical option remains controversial. To evaluate the efficacy of anterior subcutaneous transposition of the ulnar nerve in patients with moderate to severe cubital tunnel syndrome and to analyze prognostic factors, we retrospectively reviewed 62 patients（65 elbows） diagnosed with cubital tunnel syndrome who underwent anterior subcutaneous transposition. Preoperatively, the initial severity of the disease was evaluated using the Mc Gowan scale as modified by Goldberg： 18 patients（28%） had grade IIA neuropathy, 20（31%） had grade IIB, and 27（42%） had grade III. Postoperatively, according to the Wilson ＆ Krout criteria, treatment outcomes were excellent in 38 patients（58%）, good in 16（25%）, fair in 7（11%）, and poor in 4（6%）, with an excellent and good rate of 83%. A negative correlation was found between the preoperative Mc Gowan grade and the postoperative Wilson ＆ Krout score. The patients having fair and poor treatment outcomes had more advanced age, lower nerve conduction velocity, and lower action potential amplitude compared with those having excellent and good treatment outcomes. These results suggest that anterior subcutaneous transposition of the ulnar nerve is effective and safe for the treatment of moderate to severe cubital tunnel syndrome, and initial severity, advancing age, and electrophysiological parameters can affect treatment outcome.
文摘Objective： To explore the effect of electro-acupuncture and musk injection on recovery of injured sciatic nerve function in rats, so as to provide the experimental evidences for the promotion of peripheral nerve regeneration by electro-acupuncture and musk injection. Methods： Following establishing rat model of sciatic nerve injury by operation, the rats were randomly divided into electro-acupuncture group, musk injection group, electro-acupuncture plus musk injection group and model group, then sciatic functional index （SFI） and motor nerve conduction velocity （MNCV） were measured after 4 weeks of treatment, 8 weeks of treatment and 12 weeks of treatment respectively to evaluate recovery of nerve function. Results： SFI and MNCV in electro-acupuncture group, musk injection group and electro-acupuncture plus musk injection group were improved more obviously than that in model group, with significant differences（P〈0.01, P〈0.05）. Conclusions： Both electro-acupuncture and musk injection could promote recovery of injured nerve function, and they had a certain synergetic effect and might be the effective methods in promoting recovery of injured peripheral nerve function.
文摘目的系统评价针灸治疗2型糖尿病周围神经病变(DPN)对腓神经神经传导速度的影响,为针灸治疗DPN提供临床参考。方法通过检索中国生物力学文献数据库(CBM)、中国期刊全文数据库(CNKI)、维普期刊数据库(VIP)、万方数据库、Pub Med、Springer、Medline数据库,收集2000年1月至2014年1月关于针灸治疗2型DPN的随机对照试验(RCT),提取腓神经传导速度相关资料并进行方法学质量评价,采用Rev Man 5.1软件进行Meta分析。结果共纳入10个随机对照试验,合计685例患者,其中治疗组355例,对照组330例。Meta分析结果显示,针灸治疗2型DPN在提高腓神经运动神经传导速度(MNCV)和感觉神经传导速度(SNCV)方面可能优于对照组,差异均有统计学意义[MD=3.55,95%CI(0.79,6.31);MD=4.10,95%CI(0.22,7.99)]。结论针灸治疗2型DPN可以改善腓神经传导速度,值得临床应用。但由于本系统评价纳入研究较少,样本量小,且质量不高,存在偏倚的高度可能性,因此上述结论尚需要高质量、大样本、多中心的随机对照试验加以证实。
