Impact of COVID-19 on Safety Performance for Motorcycles: Pre-and during-Pandemic Conditions

Florida has the highest number of motorcycle fatalities in the United States and contains the second largest population of registered motorcycles. The COVID-19 pandemic influenced the roads, traffic, and driving behavior in the continental United States. Motorcycle crashes decreased during the COVID-19 years (2020 and 2021) while the fatality rates increased. The purpose of this study is to 1) investigate motorcycle crashes before and during the Pandemic period to understand the impacts on motorcycle safety and contributing factors to the crash severity levels;2) develop the crash predictive model for different degrees of severity in motorcycle crashes in Florida. Florida statewide crash data were collected. T tests have been conducted to compare the contributing factors between two periods. The injury severities are significantly different among all five levels between those during normal period and the Pandemic period. A crash predictive model has been developed to determine the facts to injury severity levels for motorcycle crashes. A total of eight variables are found to significantly increase the injury severity levels for motorcycle crashes during the Pandemic period.

INVESTIGATION IN REDUCING EXHAUST EMISSIONS FROM TWO STROKE MOTORCYCLES

Test results of reducing two stroke motorcycle emissions with new type carburettors and electronic fuel injection systems are presented. Analyses and comparison between different systems are discussed. The adoption of electronically controlled injection and corresponding electronic control technique is an effective measure of prolonged vitality to improve emissions from two stroke motorcycles. Suggestions about the strategic steps of China′s motorcycle emission control are proposed.

2021年老挝M_(S)6.0地震序列研究

云南地震活动与周边强震存在“构造相连,动力同源”的特征,研究周边强震的序列演化特征及发震构造,对云南地区地震研究具有重要意义。2021年12月24日老挝M_(S)6.0地震发生在滇西南地区的NW向整董断裂附近,震源机制解显示,此次地震是一次走滑型破裂事件,破裂方向与区域构造特征一致。老挝M_(S)6.0地震序列属于前震-主震-余震型序列,主震前震中附近出现3~4级地震非常活跃的现象,前震序列参数计算显示b值波动相对幅度较大,h值出现“上翘”形态,而余震序列b值和h值变化均相对平稳,主震的同震库伦应力结果表明老挝地震可能对云南地区有应力加载作用。

Research on Transient Response of Motorcycle with One Tire Colliding on Ground

Aim To study the transient response of motorcycle with one tire colliding on ground. Methods Taking the colliding velocity as an independent variable, the changing law of the biggest collision inertia load of motorcycle′s sprung mass, unsprung mass and driver was studied, while its front and rear tire colliding on ground respectively.Results and Conclusion According to the working conditions of motorcycle shock absorbers and the characteristic of response curve, the transient response of the acceleration, the velocity and the displacement were discussed section by section. And the result of simulating the actual JH125 motorcycle was given.

遗传性蛋白S缺乏症致兄弟二人患肺栓塞报告

肺栓塞(pulmonary embolism, PE)是临床上常见的急危重症之一,具有致死性,由于症状及体征均不典型,常常导致漏诊、误诊。青少年肺栓塞性相对少见,更容易被临床医师忽视。但该类患者可能发病年龄早,应注重其求因的检查尤其遗传缺陷。本文通过报道兄弟患肺栓塞病例,最终确诊为遗传性蛋白S缺乏症,且为少见的复杂杂合变异病例,而提高临床医师对于青少年PE的诊治水平。

基于“微生物-肠-脑轴”探讨补肾通腑方对APP/PS1小鼠肠道菌群及LPS/TLR4/NF-κB通路的影响

目的探讨补肾通腑方调控肠道菌群,改善阿尔茨海默病(Alzheimer’s disease,AD)模型小鼠学习记忆能力的作用机制。方法以APP/PS1小鼠为研究对象,给予补肾通腑方治疗8周,采用Morris水迷宫法观察小鼠空间学习记忆能力变化;16S rDNA检测小鼠肠道菌群丰度、多样性变化;HE染色观察海马病理形态学变化;免疫荧光检测海马区小胶质细胞活化情况;Western blot检测TLR4、NF-κB、IL-6等炎症因子表达。结果与模型组相比,补肾通腑方可以缩短AD模型小鼠逃避潜伏期、游泳路径,增加跨越平台次数(P<0.05),提升肠道菌群多样性,调节肠道菌群丰度,促进海马神经元细胞损伤修复,降低iNOS/Iba1共表达,提高Arg1/Iba1共表达(P<0.01),促进小胶质细胞从M1型向M2型转化,下调TLR4、NF-κB、IL-6等促炎因子的表达。结论补肾通腑方改善AD模型小鼠学习记忆能力的作用机制可能与调节肠道菌群介导的LPS/TLR4/NF-κB通路,从而抑制促炎型小胶质细胞活化、减轻中枢神经系统炎症、改善海马区神经元细胞损伤有关。

Performance of Pd/CeO_2-ZrO_2-Al_2O_3 catalyst for motorcycle

The Pd-only catalysts for motorcycle were prepared by impregnating CeO2-ZrO2-Al2O3 and CeO2-ZrO2+Al2O3 with PdCl2 aqueous solution and characterized by X-ray diffraction (XRD), oxygen storage capacity (OSC) and H2-temperature-programmed reduction (H2-TPR) methods. The XRD result indicated that the CeO2-ZrO2-Al2O3 compound prepared by co-precipitation formed a single solid solution and had good thermal stability, and Pd phase was not observed in all catalysts. The TPR results showed that the reduction temperature of Pd/CeO2-ZrO2-Al2O3 catalyst was lower than that of Pd/CeO2-ZrO2+Al2O3 catalyst whether they were fresh or aged catalysts. The Pd/CeO2-ZrO2-Al2O3 exhibited high three-way catalytic activity at low temperature, high thermal stability, and wide working window, suggesting a great potential for applications.

Driving Cycle for Motorcycle Using Micro-Simulation Model

Driving cycle of vehicle has been used in emission estimation and fuel consumption study. Existing method of data collection using car chasing technique is expensive. The technique using micro simulation approach is cheaper and fast to derive the driving cycle. In this paper a traffic simulation model Driving Cycle Micro-Simulation Model for Motorcycle has been developed. The issue of lateral and longitudinal movement aspect in motorcycle driving has been examined in the model. Parameters to cover such movement have been built in the model and applied on a stretch in Edinburgh city of Scotland. Results from model have been both calibrated and validated. The results show that Driving Cycle Micro-Simulation Model for Motorcycle gives better representation of driving cycle and it can be used to understand the effect of driving modes on emission for better understanding of vehicular emission control.

Fuzzy Comprehensive Evaluation Research of Goal Attainment of Green Transportation Development Policy —Take Dongguan “Motorcycle Ban” Policy as an Example

Launching the evaluation research of green transportation can grasp the green transportation implementation accurately and diagnose the existing problems. From the perspective of green transportation, this research chose Dongguan “motorcycle ban” policy as the research object, and constructed secondary evaluation index system in transportation and environmental harmony, transportation and future harmony, transportation and society harmony, transportation and resource harmony, four dimensions. Then it used fuzzy comprehensive evaluation model to do the evaluation and found that the policy’s positive effect on the Dongguan green transportation development was average. Finally, based on the evaluation results, measures and advices were proposed.

Assessment of Benchmark Dose in BEAS-2B Cells by Evaluating the Cell Relative Viability with Particulates in Motorcycle Exhaust via the Air-liquid Interface Exposure

Objective This study aimed to use an air-liquid interface(ALI)exposure system to simulate the inhalation exposure of motorcycle exhaust particulates(MEPs)and then investigate the benchmark dose(BMD)of MEPs by evaluating cell relative viability(CRV)in lung epithelial BEAS-2B cells.Methods The MEPs dose was characterized by measuring the number concentration(NC),surface area concentration(SAC),and mass concentration(MC).BEAS-2B cells were exposed to MEPs at different concentrations via ALI and CRV was determined using Cell Counting Kit(CCK-8)assay.BMD software was applied to calculate BMD and the lower limit of benchmark dose(BMDL)according to Akaike Information Coefficient(AIC),with P-value based on Hill,Linear,Polynomial,and Power model.Results Our results reveal that BMD of NC and SAC were estimated by the best-fitting Hill model,while MC was estimated by Polynomial model.The BMDL for CRV following ALI exposure to MEPs were as follows:364.2#/cm^(3)for NC;0.662×10^(7)nm^(2)/cm^(3)for SAC;and 0.278μg/m^(3)for MC.Conclusion These results indicate that MEPs exposure via ALI system induces a dose-dependent decrease of CRV and provides the potential exposure threshold of MEPs in a lung cell model.

Dynamic Response of Functional Virtual Prototyping of Motorcycle under Combined Excitations

This paper developed 3D product models of motorcycle and engine by UGNX as well as virtual prototyping by ADAMS program with road roughness generated by MATLAB. Under the straight-line running condition, the dynamic responses of motorcycle multibody system to both road and engine excitations were compared with those to only road excitation in terms of vertical acceleration response, amplitude frequency response and power spectral density. The comparisons of simulation data showed that the response due to flat road excitation was around 20 Hz, while that to the combined excitations was in a wide frequency band, of which the major components focused on 10 Hz, 15 Hz, 35 Hz ,70 Hz, 100 Hz and even higher frequencies, reflecting the characteristics of engine excitation based on its unbalanced inertia force and torque. It is concluded that the high fidelity virtual prototyping can simulate the dynamics of motorcycle product well in investigating the vibration and ride comfort performance.

Modeling and Evaluation of the Impact of Motorcycles Mobility on Vehicular Traffic

Traffic simulation can help to evaluate the impact of different mobility behaviors on the traffic flow from safety, efficiency, and environmental views. The objective of this paper is to extend the SUMO (Simulation of Urban Mobility) road traffic simulator to model and evaluate the impact of motorcycles mobility on vehicular traffic. First, we go through diverse mobility aspects and models for motorcycles in SUMO. Later, we opt for the most suitable mobility models of motorcycles. Finally, the impact of motorcycle mobility on different kinds of vehicles is investigated in terms of environment, fuel consumption, velocity and travel time. The result of modeling and evaluation shows that based on the mobility model of the motorcycle, vehicular traffic flow can be enhanced or deteriorated.

2021年漾濞M_(S)6.4地震前重力段差指标量分析及场源特征反演

基于2016-2021年云南地区流动重力重复观测资料,利用流动重力段差变化可视化方法及重力场变化显著性程度指标量G和C值研究了2021年漾濞M_(S)6.4地震前的重力变化,并反演了其与地震孕育相关的场源分布特征,开展了对研究区重力变化及场源特征的定性和定量研究。结果表明:①段差表示法的大小和方向对地下物质的运移方向有一定的指示意义,震前重力指标量呈显著上升,震后又迅速回落,重力变化指标量G和C值可作为评价测网区域重力变化显著性程度的定量依据;②反演得到的重力变化场源位置主要集中在红河断裂带北段至滇西北一带,且表现出与维西-乔后断裂及红河断裂带走向较为一致的分布特征,这可能与地震前中上地壳的深部物质运移相关。

泸定M_(S)4.5地震不对称高陡谷坡地震动响应

基于2023年四川泸定M_(S)4.5地震实测地震动数据,开展不对称斜坡时频域数据分析。结果表明:1)位于右岸1^(#)监测点的PGA放大系数最大,水平向和竖直向分别为3.16~15.08、4.37;2)Arias强度右岸最大值为2.24 cm/s,左岸最大值为0.79 cm/s,说明右岸地震动响应能量更强;3)斜坡右岸监测点的卓越频率为2~9 Hz,左岸卓越频率为2~17 Hz,地震幅值所呈现出来的能量在水平向比竖直向更为集中。地震动响应在不对称高陡谷坡右岸凸出半岛状斜坡地形比直线形斜坡更为强烈,高位覆盖层的存在会增强地震动响应。

Research on a Dispersed Networked CAD/CAM System of Motorcycle

In order to improve competitive ability of market, mo torcycle enterprises, special the small and middle sized ones must use IT to org anize social resource and adopt effective production mode, namely the dispersed networked design and manufacturing (DNDM), which was put forward and proved to b e one of vitality production modes in recent years. In responding to the new pro duction mode of VMCE, a dispersed networked CAD/CAM system (DNCADMS) of motorcyc le products should be developed. The objective of this paper is to investigate a new design and manufacturing mode and technical environment of motorcycle produ ction based on the concept of the DNDM for the small and meddle sized motorcycle enterprises. Because there are various CAx software systems, including differen t kinds of isolated CD, CAD, CAE, CAPP, CAM, PDM, and so on, are used at differe nt stages of the life period of motorcycle products under heterogeneous environm ents, to build a DNCADMS of motorcycle with high performance, some key issues, n amely the architecture of the DNCADMS, the integration of the isolated CAx softw are systems (CAxs), the data communication and exchange between these isolated s ystems and the data share problem under the dispersed heterogeneous database env ironment, should be solved well. For this, the idea we propose is the combinatio n of Web, CORBA, STEP and Java, which provides an effective mechanism to support the integration of isolated CAxs, and support communication and interoperabilit y among CAx systems. Each isolated CAx has been encapsulated respectively by a c ontainer, which is implemented by the ORBs and the IDL of the COBRA technology s tandard, and managed by the application index server. Each container is connecte d with the others by a local network or intranet/Extranet/internet and communica tes through network. For exchanging design and manufacturing information and kno wledge via a local network or the Internet, a commmerical product data translato r has been employed as a product data translating server to complete product dat a communication and exchange between the isolated CAx systems. And for solving t he data share problem under the dispersed networked heterogeneous database envir onment, the idea we propose is to build a meta-database for the native database s, which is a dispersed database, and links various native databases into a whol e logical database. For managing the meta-database, the database index server, a Java-based integrating mechanism, has been also put forward in this paper. Th e application and database index servers have been implemented with Java lan guage. Moreover, the native data base and knowledge base related to each isolate d CAx are be integrated into a dispersed database system by a meta-base.

SphK1/S1P/S1PR2信号通路促进肌生成:运动改善骨骼肌健康的新视角

背景:近年来,运动改善骨骼肌的健康已成为学者们关注的一个重要研究内容,适宜的运动对骨骼肌具有积极的作用,其中在运动激活鞘氨醇激酶1(sphingosine kinase1,SphK1)/鞘氨醇-1-磷酸(sphingosine-1-phosphate,S1P)/鞘氨醇-1-磷酸受体2(sphingosine-1-phosphate receptor2,S1PR2)信号通路如何改善骨骼肌的健康,正受到科研人员的重视。目的:研究运动经SphK1/S1P/S1PR2信号通路如何改善骨骼肌的健康,探索治疗相关肌肉疾病的新方法,以改善人的骨骼肌健康。方法:检索Web of Science、PubMed、中国知网、万方和维普数据库从建库至今与文章主题相关的文献,以“signaling pathway,SphK1,S1P,S1PR2,skeletal muscle,satellite cell,myogenesis,exercise”为英文检索词,以“信号通路,SphK1,S1P,S1PR2,骨骼肌,卫星细胞,肌生成,运动”为中文检索词,最终纳入69篇文献进行分析。结果与结论:①SphK1/S1P/S1PR2信号通路是一个复杂的调控网络,通过SphK1催化产生的S1P,与S1PR2等受体的相互作用,触发下游信号转导过程,进而调控细胞、组织、器官和系统的多种生物学功能。②SphK1/S1P/S1PR2信号通路能调控卫星细胞增殖和成肌细胞分化,改善肌生成。③文章通过文献资料调研法分析了SphK1/S1P/S1PR2信号通路的生理基础以及运动对其影响的可能性。急性有氧运动可提高骨骼肌中SphK1的表达,人体和动物研究中已证实急性和长期运动均可提高骨骼肌中S1P水平,另外研究表明长期抗阻运动可提高S1PR2在骨骼肌中的表达,部分实验结果表明急性和长期运动对肌肉或者血液中S1P水平无显著影响,出现不同结果的原因可能是选择的研究对象、方式、强度及频率不同,而具体机制尚不明确。④研究认为,运动能够促进SphK1/S1P/S1PR2信号通路在骨骼肌中的表达,调控下游相关信号通路,并且针对这一信号通路的研究可能为骨骼肌疾病的治疗提供新的策略和方法,从而改善骨骼肌健康。⑤未来应深化对SphK1/S1P/S1PR2信号通路与骨骼肌健康关联的研究,进一步揭示其与卫星细胞、成肌细胞的调控关系及与上下游通路的相互作用,挖掘其临床应用价值,制定康复方案时考虑该通路变化,探索不同运动对该通路的影响机制,并将其作为潜在治疗靶点,结合人体肌肉模型提升研究深度和准确性。

Modification of the Genetic Polymorphism of Glutathione-S-Transferase (GSTM1 and GSTT1) in Motorcycle Drivers Exposed to BTEX in Cotonou

The glutathione-S-transferase genes mainly the GSTM1 and GSTT1 alleles are responsible for the synthesis of detoxication enzymes that can remove toxic substances. The objective of this study is to seek changes in the genetic polymorphism of glutathione-S-transferase GSTM1 and GSTT1 in motorcycle drivers exposed to BTEX. Our study group consists of 60 motorcycle drivers including 30 professional and 30 non-professional. Blood samples were preleveled from the study population in the EDTA tubes and DNA was extracted by the phenol/chloroform method. The PCR technique was used to determine the presence or absence of genes. Our results showed that the percentage of GSTM1 null genotype has a statistically significant difference (P = 0.02), while the percentage of GSTT1 null genotype was non-significant (P = 0.76) between the two groups. The percentage of deletion of both genes is higher in professional than non-professional motorcycle drivers. Air pollution in Cotonou by BTEX seems to influence the deletion of the GSTM1 and GSTT1 genes at a higher percentage among professional than non-professional motorcycle drivers.

A Matlab-Based Simulation for Hybrid Electric Motorcycle

This paper presents a simulation and modeling package based on Matlab for a parallel hybrid electric motorcycle (HEM). The package consists of several main detailed models: internal combustion engine (ICE), motor, continuously variable transmission (CVT), battery, energy management system (EMS) etc . Each component is built as a library, and can be connected together according to the parallel HEM's topology. Simulation results, such as ICE power demand, motor power demand, battery instantaneous state of charge (SOC), pollution emissions etc. are given and discussed. Lastly experimental data verify our simulation results.

Performance Assessment of Motorcycle Operation, as a Means of Urban Mobility in Lokoja, Nigeria

Motorcycles contribute significantly to the number of automobiles on the roads in Lokoja, Nigeria. This scenario is attributable to pitiable public transport supply and bad roads that are synonymous to the country Nigeria. Motorcycles are the major means of urban mobility in Lokoja due to the fact that the available taxies within the town operate within a designed route only (Felele-Army Barrack and Ganaja-Felele, vice-versa). The situations have led to high increases in the number of motorcycle operators and patronages in Lokoja. To this fact, the paper assessed motorcycle operation as means of urban mobility in Lokoja. The study was conducted using questionnaires and field observation to collect the required data. Data were also collected from the Federal Road Safety Commission and Commercial Motorcycle Association of Nigeria, Lokoja to compliment the data collected from the commercial motorcycle operators and passengers in the study area. The weekly records of movement were sourced from Okada Riders Association in Lokoja. A total of 1125 commercial operators and 4000 commuters were arrived, while 10% of the populations were sampled. Altogether 113 commercial motorcycle operators and 400 passengers were sampled respectively and this amounted to 513 samples. Descriptive statistics such as frequency counts and percentages were employed in the data analysis. Findings revealed that unemployment situation in the state have led many people, particularly the youth, into the commercial motorcycle operation in the city and the ability to provide door-to-door service have made many people patronize commercial motorcycle in the area. On this note, Government should create more job opportunities, introduce the use of three wheel cycles and improve on the operational efficiencies of city taxies which will go a long way in reducing road accidents and thus reducing the influx of commercial motorcycles.