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Effects of different courses of moxibustion treatment on intestinal flora and inflammation of a rat model of knee osteoarthritis 被引量:10
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作者 Ye-juan Jia Tian-yu Li +3 位作者 Peng Han Yu Chen Li-jia Pan Chun-sheng Jia 《Journal of Integrative Medicine》 SCIE CAS CSCD 2022年第2期173-181,共9页
Objective:This study was done to determine the effects of different courses of moxibustion on a rat knee osteoarthritis(KOA)model,and explore the dose–effect relationship of moxibustion on KOA from the perspectives o... Objective:This study was done to determine the effects of different courses of moxibustion on a rat knee osteoarthritis(KOA)model,and explore the dose–effect relationship of moxibustion on KOA from the perspectives of intestinal flora and inflammatory factors.Methods:Wistar rats were randomly divided into five groups:normal,model,moxibustion for 2 weeks,moxibustion for 4 weeks and moxibustion for 6 weeks groups(n=5 each group).A KOA rat model was induced by monosodium iodoacetate,and moxibustion intervention was performed at the acupoints“Dubi”(ST35)and“Zusanli”(ST36),once every other day.Pathologic changes in the cartilage of rat knee joints were assessed after intervention,and fecal samples were subjected to 16 S r RNA high-throughput sequencing for microbial diversity analysis.Results:Damage to the knee articular cartilage was obvious in the model group,which also had increased levels of pro-inflammatory factors,decreased levels of anti-inflammatory factors,and intestinal flora disorders with decreased diversity.The degree of cartilage damage in the 4 and 6 weeks of moxibustion groups was significantly improved compared with the model group.The 4 and 6 weeks of moxibustion groups also demonstrated reduced levels of interleukin-1βand tumor necrosis factor-a and increased levels of interleukin-10(P<0.05).Both the abundance and diversity of the intestinal flora were increased,approaching those of the normal group.Abundances of probiotics Eubacterium coprostanoligenes group and Ruminococcaceae UCG-014 increased,while that of the pathogenic bacteria Lachnospiraceae NK4 A136 group decreased(P<0.05).Although the abundance of Lachnospiraceae NK4 A136 group decreased in the 2 weeks of moxibustion group compared with the model group(P<0.05),there was no statistically significant difference in serum inflammatory factors,flora species diversity or degree of pathological damage compared with the model group.Conclusion:Moxibustion treatment led to significant improvements in the intestinal flora and inflammatory factors of rats with KOA.Moxibustion treatment of 4 and 6 weeks led to better outcomes than the 2-week course.Moxibustion for 4 and 6 weeks can regulate intestinal flora dysfunction with increased probiotics and reduced pathogenic bacteria,reduce pro-inflammatory factors and increase antiinflammatory factors.No significant differences were seen between the effects of moxibustion for 4 weeks and 6 weeks. 展开更多
关键词 Knee osteoarthritis Different courses moxibustion treatment Intestinal flora Inflammatory cytokines
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A toxicological investigation of the air quality in a moxibustion treatment room as measured through particulate concentration and oxidative capacity 被引量:1
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作者 Bai-Xiao Zhao Ping Liu +5 位作者 Cha-Xi Huang Li-Xing Lao Long-Yi Shao Li-Han Ying-Xue Cui Jia Yang 《World Journal of Traditional Chinese Medicine》 2015年第2期61-67,共7页
Background: Moxibustion is a traditional Chinese medicine(TCM) therapy in which mugwort(Artemisia vulgaris) floss is burned to warm and stimulate acupoints. The modality has been used traditionally for thousands of ye... Background: Moxibustion is a traditional Chinese medicine(TCM) therapy in which mugwort(Artemisia vulgaris) floss is burned to warm and stimulate acupoints. The modality has been used traditionally for thousands of years. However, smoke-related safety issues have recently been of concern, and little is known about moxa smoke and air quality in the clinical moxibustion environment.Objective: To assess the air quality in a typical moxibustion treatment room using particulate matter(PM) concentration and DNA oxidative damage at PM10.Methods: The study was conducted in August and November to December, 2011, at a TCM clinic in Beijing, China, in a moxibustion treatment room. A moxa-free treatment room and the outdoor area adjacent to the clinic were used as controls. PM10 concentrations were monitored with a portable digital dust indicator. The oxidative capacity of whole and water-soluble fractions of PM10 were detected using plasmid DNA assay. The results were shown as TD40 values; that is, the amount of PM10 that causes plasmid DNA damage of 40%.Results: Average PM10 concentrations in the moxibustion room were 2.56 mg m^(-3) in summer and 2.78 mg m^(-3) in winter, much higher than at control sites. For whole and water-soluble fractional PM10, the average summer TD40 values collected in the moxibustion room were 791.67 μg ml^(-1) and 876.33 μg ml^(-1) respectively, and the winter values were 779.86 μg ml^(-1) and 879.57 μg ml^(-1). These results of winter samples were significantly higher(p < 0.001) than the corresponding results from control sites. However, there was no statistical difference(p = 0.06)between the TD40 values of both the whole and water-soluble fractional PM10 from the moxibustion treatment room, while differences were significant in the general treatment room(p = 0.025) and at the outdoor site(P < 0.001).Conclusion: Our study shows that moxa smoke increases PM10 concentration. However, the oxidative capacity of PM10 in the moxibustion room was much lower than that at control sites with the same particulate burden, and the bioactivity at that site was mainly from the watersoluble fraction, another difference from the controls. This unexpected bioactivity is assumed to relate to the low toxicity of moxa smoke or to its proven antioxidant activity. Overall, further research is needed. 展开更多
关键词 moxibustion treatment room moxa smoke PM10 mass concentration oxidative capacity
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APPLICATION OF PRINCIPLE OF "PREVENTION IN PREFERENCE TO TREATMENT OF DISEASES" IN ACUPUNCTURE-MOXIBUSTION CLINIC
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作者 王茎 《World Journal of Acupuncture-Moxibustion》 2004年第3期52-57,共6页
In the present paper the author reviews the viewpoint of 'preventive treatment of diseases' in the ancient literature of traditional Chinese medicine (TCN) and its clinical application from (1) prevention firs... In the present paper the author reviews the viewpoint of 'preventive treatment of diseases' in the ancient literature of traditional Chinese medicine (TCN) and its clinical application from (1) prevention first before the occurrence of diseases; and (2) preventing development after onset of diseases. In the preventive treatment of diseases, the ancient Chinese doctors usually (1) regulated qi of both Conception Vessel and Governor Vessel for health care; (2) performed regular moxibustion; and (3) applied plaster to the acupoint in summer for treating winter-diseases. In the treatment of diseases after onset, the ancient Chinese usually (1) tried best to make early diagnosis and early treatment; and (2) strengthened the related internal organ in advance to check their development; and (3) employed appropriate remedies to recuperate the patient's health. 展开更多
关键词 Preventive treatment of diseases Acupuncture and moxibustion Preventing development of diseases
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INFLUENCE OF DIFFERENT INTERVALS OF ACUPUNCTURE TREATMENT ON BONE INTENSITY IN PRIMARY OSTEOPOROSIS PATIENTS
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作者 蔡红 《World Journal of Acupuncture-Moxibustion》 2003年第2期12-15,共4页
Objective: To observe the influence of different intervals of acupuncture treatment on bone intensity in primary osteoporosis subjects. Methods: A total of 45 cases of primary osteoporosis female patients were randoml... Objective: To observe the influence of different intervals of acupuncture treatment on bone intensity in primary osteoporosis subjects. Methods: A total of 45 cases of primary osteoporosis female patients were randomly divided into 1 treatment/week (1-T/W), 2 treatments/week (2-T/W) and 3 treatments/week (3-T/W) groups, with 15 cases being in each group. Guanyuan (CV 4), Zusanli (ST 36), Sanyinjiao (SP 6), Shenshu (BL 23), Taixi (KI 3) and Pishu (BL 20) were used and stimulated with reinforcing needling manipulation. For patients with deficiency syndrome of kidney-yang, thermal acupuncture was applied to Shenshu (BL 23), and for patients with spleen-deficiency syndrome, thermal acupuncture applied to Zusanli (ST 36). Results: After 6 months’ treatment, in 1-T/W group, no apparent change of bone intensity was observed, while in 2-T/W and 3-T/W groups, the bone intensity was increased significantly (P<0.05, 0.01). Conclusion: Acupuncture plus moxibustion treatment twice or 3 times every week can obviously improve the bone intensity. 展开更多
关键词 Acupuncture and moxibustion therapies treatment interval Primary osteoporosis Bone intensity
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艾灸联合耳穴贴压治疗脑卒中肩手综合征的疗效观察 被引量:12
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作者 彭婷婷 刘从秀 《中医药临床杂志》 2015年第10期1426-1428,共3页
目的:观察艾灸联合耳穴贴压治疗肩手综合征的临床疗效。方法:将65例脑卒中后肩手综合征患者按照随机数字表法分为实验组和对照组。对照组为32例,采用常规康复训练;实验组为33例,在常规康复训练的基础上加艾灸联合耳穴贴压,治疗4周。2组... 目的:观察艾灸联合耳穴贴压治疗肩手综合征的临床疗效。方法:将65例脑卒中后肩手综合征患者按照随机数字表法分为实验组和对照组。对照组为32例,采用常规康复训练;实验组为33例,在常规康复训练的基础上加艾灸联合耳穴贴压,治疗4周。2组在治疗前后均采用目测类比评分法(VAS)、改良的Fugl-Meyer量表比较临床疗效。结果:治疗前2组偏瘫侧肩痛评分、Fugl-Meyer评分比较无统计学意义;治疗后实验组在减轻偏瘫侧疼痛和改善上肢运动功能效果优于对照组(P<0.05)。结论:在常规康复训练的基础上艾灸联合耳穴贴压治疗脑卒中后肩手综合征疗效更好。 展开更多
关键词 肩手综合征 艾灸 耳穴贴压 康复训练
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