Objective： To observe the effect of electroacupuncture （EA） and herbal cake-partitioned moxibustion on anxiety and depression in patients with Crohn＇s disease （CD） in remission. Methods： Sixty CD cases were ran...Objective： To observe the effect of electroacupuncture （EA） and herbal cake-partitioned moxibustion on anxiety and depression in patients with Crohn＇s disease （CD） in remission. Methods： Sixty CD cases were randomly allocated into an EA group （n=30） and an herbal cake-partitioned moxibustion group （n=30） using the random number table by the ratio of 1：1. In addition, 30 healthy subjects were included in a control group. Bilateral Tianshu （ST 25）, Qihai （CV 6） and Zhongwan （CV 12） were used in the EA and herbal cake- partitioned moxibustion groups. The treatment was done 3 times a week, for a total of 12 weeks. The efficacy was evaluated using self-rating anxiety scale （SAS）, self-rating depression scale （SDS） and traditional Chinese medicine （TCM） symptom scores. Results： Before treatment, the SAS and SDS scores in CD patients were remarkably higher than those in healthy subjects. After EA or herbal cake-partitioned moxibustion treatment, the SAS and SDS scores were significantly decreased in both groups, showing significant intra-group differences （P〈0.05）; the symptom scores of abdominal pain （severity, frequency and duration）, bowel sounds/flatus and general fatigue were significantly decreased, showing significant intra-group differences （P〈0.05）; however, there were no between-group statistical differences （P〉0.05）. Conclusion： Both EA and herbal cake-partitioned moxibustion can significantly decrease abnormally high SAS and SDS scores in CD patients as well as TCM symptom scores. The two therapies share similar effects in alleviating common symptoms and improving anxiety and depression.展开更多
基金supported by National Basic Research Program of China 973 Program(No.2015CB554501,No.2009CB522900)Shanghai Rising-star Program(No.16QA1403400)the Program for New Century Excellent Talents in University of Ministry of Education(No.NCET-13-0907)~~
文摘Objective： To observe the effect of electroacupuncture （EA） and herbal cake-partitioned moxibustion on anxiety and depression in patients with Crohn＇s disease （CD） in remission. Methods： Sixty CD cases were randomly allocated into an EA group （n=30） and an herbal cake-partitioned moxibustion group （n=30） using the random number table by the ratio of 1：1. In addition, 30 healthy subjects were included in a control group. Bilateral Tianshu （ST 25）, Qihai （CV 6） and Zhongwan （CV 12） were used in the EA and herbal cake- partitioned moxibustion groups. The treatment was done 3 times a week, for a total of 12 weeks. The efficacy was evaluated using self-rating anxiety scale （SAS）, self-rating depression scale （SDS） and traditional Chinese medicine （TCM） symptom scores. Results： Before treatment, the SAS and SDS scores in CD patients were remarkably higher than those in healthy subjects. After EA or herbal cake-partitioned moxibustion treatment, the SAS and SDS scores were significantly decreased in both groups, showing significant intra-group differences （P〈0.05）; the symptom scores of abdominal pain （severity, frequency and duration）, bowel sounds/flatus and general fatigue were significantly decreased, showing significant intra-group differences （P〈0.05）; however, there were no between-group statistical differences （P〉0.05）. Conclusion： Both EA and herbal cake-partitioned moxibustion can significantly decrease abnormally high SAS and SDS scores in CD patients as well as TCM symptom scores. The two therapies share similar effects in alleviating common symptoms and improving anxiety and depression.
