“Intel Multi-Core师资培训研讨班”在浙大顺利举办

2006年12月19-21日，在“水光滟潋、山色空蒙”的美丽杭州——浙江大学软件学院举行了为期三天的“Intel Multi-Core师资培训研讨班”。参加此次培训的老师超过40人，主要来自全国各省市重点高校，其中有南京大学、电子科技大学、西安交通大学、同济大学、北京邮电大学、东北大学、四川大学、山东大学、北京交通大学、深圳大学等。参加培训的老师来自各个院系，包括软件学院、信息学院、计算机系，电子工程系等。

Enrichment of Fetal Nucleated Red Blood Cells by Multi-core Magnetic Composite Particles for Non-invasive Prenatal Diagnosis

A novel kind of multi-core magnetic composite particles, the surfaces of which were respectively mo- dified with goat-anti-mouse IgG and antitransferrin receptor（anti-CD71）, was prepared. The fetal nucleated red blood cells（FNRBCs） in the peripheral blood of a gravida were rapidly and effectively enriched and separated by the mo- dified multi-core magnetic composite particles in an external magnetic field. The obtained FNRBCs were used for the identification of the fetal sex by means of fluorescence in situ hybridization（FISH） technique. The results demonstrate that the multi-core magnetic composite particles meet the requirements for the enrichment and speration of FNRBCs with a low concentration and the accuracy of detetion for the diagnosis of fetal sex reached to 95%. Moreover, the obtained FNRBCs were applied to the non-invasive diagnosis of Down syndrome and chromosome 3p21 was de- tected. The above facts indicate that the novel multi-core magnetic composite particles-based method is simple, relia- ble and cost-effective and has opened up vast vistas for the potential application in clinic non-invasive prenatal diag- nosis.

A 3D Nonhydrostatic Compressible Atmospheric Dynamic Core by Multi-moment Constrained Finite Volume Method

A 3D compressible nonhydrostatic dynamic core based on a three-point multi-moment constrained finite-volume (MCV) method is developed by extending the previous 2D nonhydrostatic atmospheric dynamics to 3D on a terrainfollowing grid. The MCV algorithm defines two types of moments: the point-wise value (PV) and the volume-integrated average (VIA). The unknowns (PV values) are defined at the solution points within each cell and are updated through the time evolution formulations derived from the governing equations. Rigorous numerical conservation is ensured by a constraint on the VIA moment through the flux form formulation. The 3D atmospheric dynamic core reported in this paper is based on a three-point MCV method and has some advantages in comparison with other existing methods, such as uniform third-order accuracy, a compact stencil, and algorithmic simplicity. To check the performance of the 3D nonhydrostatic dynamic core, various benchmark test cases are performed. All the numerical results show that the present dynamic core is very competitive when compared to other existing advanced models, and thus lays the foundation for further developing global atmospheric models in the near future.

Variation-Aware Task Mapping on Homogeneous Fault-Tolerant Multi-Core Network-on-Chips

A variation-aware task mapping approach is proposed for a multi-core network-on-chips with redundant cores, which includes both the design-time mapping and run-time scheduling algorithms. Firstly, a design-time genetic task mapping algorithm is proposed during the design stage to generate multiple task mapping solutions which cover a maximum range of chips. Then, during the run, one optimal task mapping solution is selected. Additionally, logical cores are mapped to physically available cores. Both core asymmetry and topological changes are considered in the proposed approach. Experimental results show that the performance yield of the proposed approach is 96% on average, and the communication cost, power consumption and peak temperature are all optimized without loss of performance yield.

Theoretical Analysis on Inter-Core Crosstalk Suppression Model for Multi-Core Fiber

Decreasing mode coupling coefficient(κ) is an effective approach to suppress the inter-core crosstalk. Therefore, we deploy a low index rod and rectangle trench in the middle of two neighboring cores to reduce κ so that the overlap of electric field distribution can be suppressed. We also propose approximate analytical solution(AAS) for κ of two crosstalk suppression models, which are two cores with one low index rod deployed in the middle and two cores with one low index rectangle trench deployed in the middle. We then do some modification for the results obtained by AAS and the modified results are proved to agree well with that obtained by finite element method(FEM). Therefore, we can use the modified AAS to get inter-core crosstalk for abovementioned two models quickly.

Modeling of Few-Mode Multi-Core Optical Fiber Channel Based on Non-Uniform Mode Field Distribution

In this paper, the influencing factors that affect few-mode and multi core optical fiber channel are analyzed in a comprehensive way. The theoretical modeling and computer simulation of the information channel are carried out and then the modeling scheme of few-mode multicore optical fiber channel based on non-uniform mode field distribution is put forward. The proposed modeling scheme can not only exponentially increases the system capacity through fewmode multi-core optical fiber channel, but has better transmission performance compared to the channel of the same type to the uniform channel revealing from the simulation results.

RF-TSV DESIGN, MODELING AND APPLICATION FOR 3D MULTI-CORE COMPUTER SYSTEMS

The state-of-the-art multi-core computer systems are based on Very Large Scale three Dimensional (3D) Integrated circuits (VLSI). In order to provide high-speed vertical data transmission in such 3D systems, efficient Through-Silicon Via (TSV) technology is critically important. In this paper, various Radio Frequency (RF) TSV designs and models are proposed. Specifically, the Cu-plug TSV with surrounding ground TSVs is used as the baseline structure. For further improvement, the dielectric coaxial and novel air-gap coaxial TSVs are introduced. Using the empirical parameters of these coaxial TSVs, the simulation results are obtained demonstrating that these coaxial RF-TSVs can provide two-order higher of cut-off frequencies than the Cu-plug TSVs. Based on these new RF-TSV technologies, we propose a novel 3D multi-core computer system as well as new architectures for manipulating the interfaces between RF and baseband circuit. Taking into consideration the scaling down of IC manufacture technologies, predictions for the performance of future generations of circuits are made. With simulation results indicating energy per bit and area per bit being reduced by 7% and 11% respectively, we can conclude that the proposed method is a worthwhile guideline for the design of future multi-core computer ICs.

Check Point VPN-1 Power Multi—core采用加速技术提供吉比特处理能力

Check Point软件技术有限公司全新的VPN-1 Power Multi—core已经面市。该方案采用了Check Point在2006年5月推出、正在申请专利的CoreXL加速技术，能在安全及性能表现方面取得平衡，确保用户在取得最高水平的整合应用安全保护的同时，不会影响网络的数据传输流畅度而影响最终用户的互联网使用体验。

基于OpenMP的Multi-Critical分子动力学并行算法优化

为提高分子动力学模拟在多核共享内存式服务器上的运算速度,在现有的分子动力学并行算法基础上提出了Multi-Critical算法。该算法使用手动划分力矩阵的方法,使多个线程进入不同名的临界区,并使用分块叠加的方法优化了并行算法,提高了并行效率。实验结果表明,对比之前的Critical算法,该算法的加速比和并行效率均有较大幅度的提高。

基于Multi-Agent建筑工程概预算系统的设计

近年来Agent及Multi-Agent技术发展迅速。文中分析了建筑概预算系统中引入Agent的必要性,阐明了Agent在建筑概预算中应用的意义,并根据建筑工程概预算特点,针对当前各种概预算软件智能性不高的问题,结合Agent技术,采用"内核—类集"的构造方式,设计了一套基于Multi-Agent的建筑工程概预算系统(MA-CBS)的整体框架,详细描述了施工图Agent的内部结构和实现算法,最后介绍了系统各个Agent间通信的语言、方式和结构。该系统具有分布性、并行性和可拓展性,提高了编制概预算文件的自动化程度。

MicroRNA-185-5p mediates regulation of SREBP2 expression by hepatitis C virus core protein

AIM: To investigate the molecular mechanism for regulation of cholesterol metabolism by hepatitis C virus(HCV) core protein in Hep G2 cells.METHODS: HCV genotype 1b core protein was cloned and expressed in Hep G2 cells. The cholesterol content was determined after transfection. The expression of sterol regulatory element binding protein 2(SREBP2) and the rate-limiting enzyme in cholesterol synthesis(HMGCR) was measured by quantitative real-time PCR and immunoblotting after transfection. The effects of core protein on the SREBP2 promoter and 3'-untranslated region were analyzed by luciferase assay. We used different target predictive algorithms, micro RNA(mi RNA) mimics/inhibitors, and site-directed mutation to identify a putative target of a particular mi RNA.RESULTS: HCV core protein expression in Hep G2 cells increased the total intracellular cholesterol level(4.05 ± 0.17 vs 6.47 ± 0.68, P = 0.001), and this increase corresponded to an increase in SREBP2 and HMGCR m RNA levels(P = 0.009 and 0.037, respectively) and protein expression. The molecular mechanism studyrevealed that the HCV core protein increased the expression of SREBP2 by enhancing its promoter activity(P = 0.004). In addition, mi R-185-5p expression was tightly regulated by the HCV core protein(P = 0.041). Moreover, overexpression of mi R-185-5p repressed the SREBP2 m RNA level(P = 0.022) and protein expression. In contrast, inhibition of mi R-185-5p caused upregulation of SREBP2 protein expression. mi R-185-5p was involved in the regulation of SREBP2 expression by HCV core protein. CONCLUSION: HCV core protein disturbs the cholesterol homeostasis in Hep G2 cells via the SREBP2 pathway; mi R-185-5p is involved in the regulation of SREBP2 by the core protein.

Multi-features Based Approach for Moving Shadow Detection

In the video-based surveillance application, moving shadows can affect the correct localization and detection of moving objects. This paper aims to present a method for shadow detection and suppression used for moving visual object detection. The major novelty of the shadow suppression is the integration of several features including photometric invariant color feature, motion edge feature, and spatial feature etc. By modifying process for false shadow detected, the averaging detection rate of moving object reaches above 90% in the test of Hall-Monitor sequence.

The Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST)

The Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST, also called the Guo Shou Jing Telescope) is a special reflecting Schmidt telescope. LAMOST’s special design allows both a large aperture (effective aperture of 3.6 m–4.9 m) and a wide field of view (FOV) (5°). It has an innovative active reflecting Schmidt configuration which continuously changes the mirror’s surface that adjusts during the observation process and combines thin deformable mirror active optics with segmented active optics. Its primary mirror (6.67m×6.05 m) and active Schmidt mirror (5.74m×4.40 m) are both segmented, and composed of 37 and 24 hexagonal sub-mirrors respectively. By using a parallel controllable fiber positioning technique, the focal surface of 1.75 m in diameter can accommodate 4000 optical fibers. Also, LAMOST has 16 spectrographs with 32 CCD cameras. LAMOST will be the telescope with the highest rate of spectral acquisition. As a national large scientific project, the LAMOST project was formally proposed in 1996, and approved by the Chinese government in 1997. The construction started in 2001, was completed in 2008 and passed the official acceptance in June 2009. The LAMOST pilot survey was started in October 2011 and the spectroscopic survey will launch in September 2012. Up to now, LAMOST has released more than 480 000 spectra of objects. LAMOST will make an important contribution to the study of the large-scale structure of the Universe, structure and evolution of the Galaxy, and cross-identification of multiwaveband properties in celestial objects.

From molecular dynamics to lattice Boltzmann:a new approach for pore-scale modeling of multi-phase flow

Most current lattice Boltzmann （LBM） models suffer from the deficiency that their parameters have to be obtained by fitting experimental results. In this paper, we propose a new method that integrates the molecular dynamics （MD） simulation and LBM to avoid such defect. The basic idea is to first construct a molecular model based on the actual components of the rock-fluid system, then to compute the interaction force between the rock and the fluid of different densities through the MD simulation. This calculated rock-fluid interaction force, combined with the fluid-fluid force determined from the equation of state, is then used in LBM modeling. Without parameter fitting, this study presents a new systematic approach for pore-scale modeling of multi-phase flow. We have validated this ap- proach by simulating a two-phase separation process and gas-liquid-solid three-phase contact angle. Based on an actual X-ray CT image of a reservoir core, we applied our workflow to calculate the absolute permeability of the core, vapor-liquid H20 relative permeability, and capillary pressure curves.

Intact Polar and Core Tetraether Lipids in Sediments from the Haiyang 4 Cold-seep of the Northern South China Sea and their Implications

A number of cold seeps have been discovered in the northern South China Sea(SCS) including the Haiyang 4 cold-seep area where Core 973-5 was collected. Intact polar lipids(IPLs) and core lipids(CLs) were analyzed separately in sediments from Core 973-5. The most abundant lipid biomarkers were isoprenoidal GDGTs(iso GDGTs), with Crenarchaeol and GDGT-0 predominating. IPL-iso GDGTs and CL-iso GDGTs were mainly derived from Thaumarchaeota. IPL-iso GDGTs were mainly produced and retained in situ thus containing most of the in situ microbiological information. Branched GDGTs were predominantly derived from generated in marine production, and mixed with some terrestrial inputs. All IPLs groups presented a high value in the sulfate-methane transition zone(SMTZ). Furthermore, IPL and CL-MI, IPL-R;showed the highest values within the SMTZ, while IPL and CL-R;had the lowest values at the SMTZ, suggesting that the contribution of Methanophila and methanogenic to GDGTs increased, while the contribution of ammonia-oxidizing Archaea to GDGTs decreased at the SMTZ.

基于HT-STWLS的配电网PMU设计

随着分布式能源和可调负荷大量接入配电网,其随机性和间歇性增加了配电网信号量测的难度,同时配电网存在节点分支类型变化多、通信条件受限等不确定因素,使相量量测单元(PMU)在配电网中应用受到限制。针对配电网节点多分支特点和量测估计高精度要求等问题,提出了基于HT-STWLS的新型配电网同步量测单元,并搭建了实验装置。首先,该装置采用多核分布式结构,通过网络路由模式,能够有效解决节点多分支量测问题,增强节点边缘计算能力;然后,对装置采集信号进行希尔伯特变换(HT)处理后,将数据代入到对称泰勒加权最小二乘(STWLS)过程中进行信号参数估计,获取高精度基波参数值;最后,通过算法验证和实际电网信号的测试,表明所提装置的HT-STWLS算法能够实现配电网信号参数的高精度估计。

Realization of a broadband terahertz wavelength-selective coupling based on five-core fibers

We propose a novel kind of wavelength-selective coupling for the terahertz range based on solid five-core fiber （FCF）. The performances of coupling, propagation characteristics, and confinement loss properties are numerically investigated by using a full vector beam propagation method （BPM）. Simulation results show that it is possible to realize a broad- band wavelength-selective coupling. The coupling length can reach 1.913 cm, and the confinement loss is better than 1.965 ×10^-4 cm^-1. Furthermore, a parameter, the power difference, is defined, and it numerically demonstrates the working performance of the wavelength-selective coupler; that is, when the power difference is better than - 15 dB, the frequency located in the range of 0.76 THz-100 THz is separated relatively well from the frequency of 0.3 THz. Finally, the effect of the structural parameter on the working performance of the coupler is also investigated. We show that the performance optimization is possible by appropriately tuning the core diameter, and the tunabilities of frequency and bandwidth are possible by appropriately tuning the pitch. The wavelength-selective coupler is of potential application for optical fiber sensing and communication in terahertz wavelength division multiplexer fields.

适用于S-NUCA异构处理器的任务调度与热管理系统

异构多核处理器凭借其高性能、低功耗和广泛的应用场景而成为当前计算机平台的主流方案,且大容量的非均匀缓存架构(S-NUCA)具有较低的平均访问时间。然而,不断上升的晶体管规模给异构多核处理器的资源调度和功耗控制带来挑战,传统的调度算法在面对基于S-NUCA的多核处理器时忽略了核心之间的缓存访问延迟,且传统热管理方案只提供芯片级功率约束,容易使得系统因核心使用率降低而造成性能下降。为此,提出一种适用于S-NUCA异构多核系统、满足热安全约束的动态线程调度机制TSCDM。利用基于动态每周期指令(IPC)值的阶段检测技术,并基于人工神经网络预测线程的IPC值,以获取线程与核心类型的最佳绑定关系,依据S-NUCA缓存特性获得最优映射和基于任务分类的任务迁移策略。在此基础上,TSCDM基于片上热模型为每个核心实时分配功率预算。在HotSniper上运行SPLASH-2性能测试套件进行实验,结果表明,相较于传统调度方案与基于机器学习的调度方案,TSCDM在加速比和资源利用率上均表现出优势,TSCDM中使用的基于瞬态温度的安全功率算法相比传统热安全功率算法能够降低核心热余量,同时处理器的全频段均有更高的能效比。