AIM to observe the effect of targeted therapy with 64-slice spiral computed tomography (CT) combined with cryoablation for liver cancer. METHODS A total of 124 patients ( 142 tumors) were enrolled into this study. Acc...AIM to observe the effect of targeted therapy with 64-slice spiral computed tomography (CT) combined with cryoablation for liver cancer. METHODS A total of 124 patients ( 142 tumors) were enrolled into this study. According to the use of dual-slice spiral CT or 64-slice spiral CT as a guide technology, patients were divided into two groups: dual-slice group (n = 56, 65 tumors) and 64-slice group (n = 8, 77 tumors). All patients were accepted and received targeted therapy by an argon-helium superconducting surgery system. The guided scan times of the two groups was recorded and compared. In the two groups, the lesion ice coverage in diameter of >= 3 cm and < 3 cm were recorded, and freezing effective rate was compared. Hepatic perfusion values [ hepatic artery perfusion (HAP), portal vein perfusion (PVP), and the hepatic arterial perfusion index (HAPI)] of tumor tissues, adjacent tissues and normal liver tissues at preoperative and postoperative four weeks in the two groups were compared. Local tumor changes were recorded and efficiency was compared at four weeks post-operation. Adverse events were recorded and compared between the two groups, including fever, pain, frostbite, nausea, vomiting, pleural effusion and abdominal bleeding. RESULTS Guided scan times in the dual-slice group was longer than that in the 64-slice group (t = 11.445, P = 0.000). The freezing effective rate for tumors < 3 cm in diameter in the dual-slice group (81.58%) was lower than that in the 64-slice group (92.86%) (chi(2) = 5.707, P = 0.017). The HAP and HAPI of tumor tissues were lower at four weeks post-treatment than at pretreatment in both groups (all P < 0.05), and those in the 64-slice group were lower than that in the dual-slice group ( all P < 0.05). HAP and PVP were lower and HAPI was higher in tumor adjacent tissues at post-treatment than at pre-treatment ( all P < 0.05). Furthermore, the treatment effect and therapeutic efficacy in the dual-slice group were lower than the 64-slice group at four weeks post-treatment (all P < 0.05). Moreover, pleural effusion and intraperitoneal hemorrhage occurred in patients in the dual-slice group, while no complications occurred in the 64-slice group (all P < 0.05). CONCLUSION 64-slice spiral CT applied with cryoablation in targeted therapy for liver cancer can achieve a safe and effective freezing treatment, so it is worth being used.展开更多
目的探讨1.5 T磁共振成像(magnetic resonance imaging,MRI)与64排多层螺旋计算机体层成像(computed tomography,CT)对脊柱骨折的诊断价值。方法方便选取2021年1月—2022年12月泰兴市第二人民医院收治的82例疑似脊柱骨折患者作为研究对...目的探讨1.5 T磁共振成像(magnetic resonance imaging,MRI)与64排多层螺旋计算机体层成像(computed tomography,CT)对脊柱骨折的诊断价值。方法方便选取2021年1月—2022年12月泰兴市第二人民医院收治的82例疑似脊柱骨折患者作为研究对象,均予1.5 T MRI与64排多层螺旋CT检查,以手术结果为金标准,评估两种技术对脊柱骨折的诊断效能,并分析其对脊柱骨折分型的诊断价值。结果1.5 T MRI对脊柱骨折诊断的准确度、灵敏度与64排螺旋CT比较,差异无统计学意义(P均>0.05)。两种方法与金标准一致性均较好(kappa值≥0.75)。1.5 T MRI对脊柱骨折A、B、C型分型诊断整体符合率为97.56%,高于64排多层螺旋CT的86.59%,差异有统计学意义(χ^(2)=7.111,P<0.05)。结论1.5 T MRI与64排螺旋CT对脊柱骨折诊断效能相当,但1.5 T MRI的分型诊断效能更高。展开更多
基金Supported by Hebei Province Health Department of Scientific Research fund project,No.20110157
文摘AIM to observe the effect of targeted therapy with 64-slice spiral computed tomography (CT) combined with cryoablation for liver cancer. METHODS A total of 124 patients ( 142 tumors) were enrolled into this study. According to the use of dual-slice spiral CT or 64-slice spiral CT as a guide technology, patients were divided into two groups: dual-slice group (n = 56, 65 tumors) and 64-slice group (n = 8, 77 tumors). All patients were accepted and received targeted therapy by an argon-helium superconducting surgery system. The guided scan times of the two groups was recorded and compared. In the two groups, the lesion ice coverage in diameter of >= 3 cm and < 3 cm were recorded, and freezing effective rate was compared. Hepatic perfusion values [ hepatic artery perfusion (HAP), portal vein perfusion (PVP), and the hepatic arterial perfusion index (HAPI)] of tumor tissues, adjacent tissues and normal liver tissues at preoperative and postoperative four weeks in the two groups were compared. Local tumor changes were recorded and efficiency was compared at four weeks post-operation. Adverse events were recorded and compared between the two groups, including fever, pain, frostbite, nausea, vomiting, pleural effusion and abdominal bleeding. RESULTS Guided scan times in the dual-slice group was longer than that in the 64-slice group (t = 11.445, P = 0.000). The freezing effective rate for tumors < 3 cm in diameter in the dual-slice group (81.58%) was lower than that in the 64-slice group (92.86%) (chi(2) = 5.707, P = 0.017). The HAP and HAPI of tumor tissues were lower at four weeks post-treatment than at pretreatment in both groups (all P < 0.05), and those in the 64-slice group were lower than that in the dual-slice group ( all P < 0.05). HAP and PVP were lower and HAPI was higher in tumor adjacent tissues at post-treatment than at pre-treatment ( all P < 0.05). Furthermore, the treatment effect and therapeutic efficacy in the dual-slice group were lower than the 64-slice group at four weeks post-treatment (all P < 0.05). Moreover, pleural effusion and intraperitoneal hemorrhage occurred in patients in the dual-slice group, while no complications occurred in the 64-slice group (all P < 0.05). CONCLUSION 64-slice spiral CT applied with cryoablation in targeted therapy for liver cancer can achieve a safe and effective freezing treatment, so it is worth being used.
文摘目的探讨1.5 T磁共振成像(magnetic resonance imaging,MRI)与64排多层螺旋计算机体层成像(computed tomography,CT)对脊柱骨折的诊断价值。方法方便选取2021年1月—2022年12月泰兴市第二人民医院收治的82例疑似脊柱骨折患者作为研究对象,均予1.5 T MRI与64排多层螺旋CT检查,以手术结果为金标准,评估两种技术对脊柱骨折的诊断效能,并分析其对脊柱骨折分型的诊断价值。结果1.5 T MRI对脊柱骨折诊断的准确度、灵敏度与64排螺旋CT比较,差异无统计学意义(P均>0.05)。两种方法与金标准一致性均较好(kappa值≥0.75)。1.5 T MRI对脊柱骨折A、B、C型分型诊断整体符合率为97.56%,高于64排多层螺旋CT的86.59%,差异有统计学意义(χ^(2)=7.111,P<0.05)。结论1.5 T MRI与64排螺旋CT对脊柱骨折诊断效能相当,但1.5 T MRI的分型诊断效能更高。
