BACKGROUND： Genotypes of hepatitis C virus （HCV） are distributed differently across the world. There is a paucity of such data in a multi-ethnic Asian population like Malaysia. The objectives of this study were to ...BACKGROUND： Genotypes of hepatitis C virus （HCV） are distributed differently across the world. There is a paucity of such data in a multi-ethnic Asian population like Malaysia. The objectives of this study were to determine the distribution of HCV genotypes between major ethnic groups and to ascer- tain their association with basic demographic variables like age and gender.展开更多
<strong>Background: </strong>Given the increase in the numbers of expatriates in Saudi Arabia and the shortage of information about expatriates’ oral health and periodontal disease severity and progressio...<strong>Background: </strong>Given the increase in the numbers of expatriates in Saudi Arabia and the shortage of information about expatriates’ oral health and periodontal disease severity and progression. <strong>Objectives: </strong>This study aimed to evaluate the effects of the racial differences on oral health and periodontal disease extent, staging, and grading among the multi-ethnic expatriates in the Aseer region, Saudi Arabia. <strong>Materials and Methods:</strong> This cross-sectional study was carried out on 300 expatriates in Aseer region, Saudi Arabia. They were divided into three equal racial different groups (n = 100), Arabs (AR), Asians (AS), and Africans (AF). The interviews of all participants were completed then the clinical examinations of periodontal diseases extent, staging, and grading parameters were performed. Statistical analysis was done by ANOVA test, Tukey’s test, and Chi-square test. The statistical significance level was determined at p < 0.05. <strong>Results: </strong>There were statistically significant differences in the comparison between the three ethnic/racial groups in clinical parameters except in GBI, PCR, FI, TFO, and BC, where there were no statistically significant differences in the comparison between the three ethnic/racial groups. There were differences associated with age, gender, smoking, and diabetes, without statistically significant differences among the three racial groups.<strong> Conclusion:</strong> We concluded that most participants in this study had a generalized severe grade 4 plaque-induced gingivitis and localized periodontitis stage III grade B.展开更多
It is a scorching summer in Huocheng County, Yining City, northwest China＇s Xinjiang Uygur Autonomous Region. Sarim Airsha and his wife Zhang Jinhua are preparing lunch in their kitchen close to the green vineyard. T...It is a scorching summer in Huocheng County, Yining City, northwest China＇s Xinjiang Uygur Autonomous Region. Sarim Airsha and his wife Zhang Jinhua are preparing lunch in their kitchen close to the green vineyard. They share the cook- ing： Sarim slices carrots into small pieces on the chopping board, while Zhang cleans展开更多
The Xinjiang Uygur Autonomous Region （also called Xinjiang for short）, situated in the border area of northwest China and the hinterland of the Eurasian Continent, occupies an area of 1.6649 million sq km, accountin...The Xinjiang Uygur Autonomous Region （also called Xinjiang for short）, situated in the border area of northwest China and the hinterland of the Eurasian Continent, occupies an area of 1.6649 million sq km, accounting for one sixth of Chinese territory. It has a land border of 5,600 km bounded by eight countries. It was an important section of the ancient Silk Road. According to statistics,展开更多
Human genetic variants have long been known to play an important role in both Mendelian disorders and common diseases. Notably, pathogenic variants are not limited to single-nucleotide variants. It has become apparent...Human genetic variants have long been known to play an important role in both Mendelian disorders and common diseases. Notably, pathogenic variants are not limited to single-nucleotide variants. It has become apparent that human diseases can also be caused by copy number variations （CNVs）, especially patient- specific novel CNVs （lafrate et al., 2004; Sebat et al., 2004; Redon et al., 2006; LuDski, 2007; Zhan~ et al.. 2009： Wu et al.. 2015）.展开更多
基金supported by University of Malaya High Impact Research grant(UM.C/625/1/HIR/MOHE/MED/31)
文摘BACKGROUND： Genotypes of hepatitis C virus （HCV） are distributed differently across the world. There is a paucity of such data in a multi-ethnic Asian population like Malaysia. The objectives of this study were to determine the distribution of HCV genotypes between major ethnic groups and to ascer- tain their association with basic demographic variables like age and gender.
文摘<strong>Background: </strong>Given the increase in the numbers of expatriates in Saudi Arabia and the shortage of information about expatriates’ oral health and periodontal disease severity and progression. <strong>Objectives: </strong>This study aimed to evaluate the effects of the racial differences on oral health and periodontal disease extent, staging, and grading among the multi-ethnic expatriates in the Aseer region, Saudi Arabia. <strong>Materials and Methods:</strong> This cross-sectional study was carried out on 300 expatriates in Aseer region, Saudi Arabia. They were divided into three equal racial different groups (n = 100), Arabs (AR), Asians (AS), and Africans (AF). The interviews of all participants were completed then the clinical examinations of periodontal diseases extent, staging, and grading parameters were performed. Statistical analysis was done by ANOVA test, Tukey’s test, and Chi-square test. The statistical significance level was determined at p < 0.05. <strong>Results: </strong>There were statistically significant differences in the comparison between the three ethnic/racial groups in clinical parameters except in GBI, PCR, FI, TFO, and BC, where there were no statistically significant differences in the comparison between the three ethnic/racial groups. There were differences associated with age, gender, smoking, and diabetes, without statistically significant differences among the three racial groups.<strong> Conclusion:</strong> We concluded that most participants in this study had a generalized severe grade 4 plaque-induced gingivitis and localized periodontitis stage III grade B.
文摘It is a scorching summer in Huocheng County, Yining City, northwest China＇s Xinjiang Uygur Autonomous Region. Sarim Airsha and his wife Zhang Jinhua are preparing lunch in their kitchen close to the green vineyard. They share the cook- ing： Sarim slices carrots into small pieces on the chopping board, while Zhang cleans
文摘The Xinjiang Uygur Autonomous Region （also called Xinjiang for short）, situated in the border area of northwest China and the hinterland of the Eurasian Continent, occupies an area of 1.6649 million sq km, accounting for one sixth of Chinese territory. It has a land border of 5,600 km bounded by eight countries. It was an important section of the ancient Silk Road. According to statistics,
基金supported by the National Basic Research Program of China(No.2012CB944600)the National Key Research and Development Program of China(No.2016YFC0905100)+1 种基金the National Natural Science Foundation of China(Nos.31521003,31625015,31571297,31601046,31525014 and 91331204)the Science and Technology Commission of Shanghai Municipality(No.16YF1413900)
文摘Human genetic variants have long been known to play an important role in both Mendelian disorders and common diseases. Notably, pathogenic variants are not limited to single-nucleotide variants. It has become apparent that human diseases can also be caused by copy number variations （CNVs）, especially patient- specific novel CNVs （lafrate et al., 2004; Sebat et al., 2004; Redon et al., 2006; LuDski, 2007; Zhan~ et al.. 2009： Wu et al.. 2015）.
