Purpose: To evaluate the additive IOP effect of physical aerobic exercise (bicycle ergometer), in healthy individuals, after the in- stillation of b-blockers. Material: 20 healthy individuals. Methods: The IOP was mea...Purpose: To evaluate the additive IOP effect of physical aerobic exercise (bicycle ergometer), in healthy individuals, after the in- stillation of b-blockers. Material: 20 healthy individuals. Methods: The IOP was measured before and 2 hours after the instillation of eye drops (b-blockers) in the right eye (OD) of the individuals.. The IOP was measured again within 5 minutes after the completion of physical exercise on a bicycle ergometer (about 10 minutes of duration - till exhaustion). Results: The instillation of b-blocker eye drops in the right eye was followed by an IOP decrease after 2 hours. The IOP decreased further more after the performance of the bicycle ergometer exercise. Mean IOP before the instillation of b-blocker. right eyes: 16.25, left eyes: 16.15. Mean IOP after the instillation of b-blocker. right eyes: 12.35 (decrease ranged from 3 to 5 mm Hg), left eyes: 14.20.. The IOP lowering effect after the bicycle ergometer exercise for the right eyes ranged from 1 to 5 mmHg. Mean IOP 10.20.展开更多
Oxygen uptake(V O_(2))was measured during a non-exhaustive high-intensity intermittent cross-exercise(HIICE)protocol consisting of four alternating bouts of 20 s running(R)and three bouts of bicycle exercise(BE)at~160...Oxygen uptake(V O_(2))was measured during a non-exhaustive high-intensity intermittent cross-exercise(HIICE)protocol consisting of four alternating bouts of 20 s running(R)and three bouts of bicycle exercise(BE)at~160%and~170%maximal oxygen uptake(V O_(2)max),respectively,with 10 s between-bout rests(sequence R-BE-R-BER-BE-R).The V O_(2) during the last BE([52.2±5.0]mL⋅kg^(-1)⋅min^(-1))was significantly higher than the V O_(2)max of the BE([48.0±5.4]mL⋅kg^(-1)⋅min^(-1),n=30)and similar to that of running.For clarifying the underlying mechanisms,a corresponding HIICE-protocol with BE and arm cranking ergometer exercise(AC)was used(sequence AC-AC-BE-AC-BE-AC-AC-BE).In some experiments,thigh blood flow was occluded by a cuff around the upper thigh.Without occlusion,the V O_(2) during the AC([39.2±7.1]mL⋅kg^(-1)⋅min^(-1)[6th bout])was significantly higher than the V O_(2)max of AC([30.2±4.4]mL⋅kg^(-1)⋅min^(-1),n=7).With occlusion,the corresponding V O_(2)([29.8±3.9]mL⋅kg^(-1)⋅min^(-1))was reduced to that of the V O_(2)max of AC and significantly less than the V O_(2) without occlusion.These findings suggest that during the last bouts of HIICE may exceed the of the specific exercise,probably because it is a summation of the V O_(2) for the ongoing exercise plus excess post-oxygen consumption(EPOC)produced by the previous exercise with a higher V O_(2)max.展开更多
文摘Purpose: To evaluate the additive IOP effect of physical aerobic exercise (bicycle ergometer), in healthy individuals, after the in- stillation of b-blockers. Material: 20 healthy individuals. Methods: The IOP was measured before and 2 hours after the instillation of eye drops (b-blockers) in the right eye (OD) of the individuals.. The IOP was measured again within 5 minutes after the completion of physical exercise on a bicycle ergometer (about 10 minutes of duration - till exhaustion). Results: The instillation of b-blocker eye drops in the right eye was followed by an IOP decrease after 2 hours. The IOP decreased further more after the performance of the bicycle ergometer exercise. Mean IOP before the instillation of b-blocker. right eyes: 16.25, left eyes: 16.15. Mean IOP after the instillation of b-blocker. right eyes: 12.35 (decrease ranged from 3 to 5 mm Hg), left eyes: 14.20.. The IOP lowering effect after the bicycle ergometer exercise for the right eyes ranged from 1 to 5 mmHg. Mean IOP 10.20.
基金supported in part by a KAKENHI Grant-in-Aid for Challenging Exploratory Research 26560406 from the Japan Society for the Promotion of Sciences.
文摘Oxygen uptake(V O_(2))was measured during a non-exhaustive high-intensity intermittent cross-exercise(HIICE)protocol consisting of four alternating bouts of 20 s running(R)and three bouts of bicycle exercise(BE)at~160%and~170%maximal oxygen uptake(V O_(2)max),respectively,with 10 s between-bout rests(sequence R-BE-R-BER-BE-R).The V O_(2) during the last BE([52.2±5.0]mL⋅kg^(-1)⋅min^(-1))was significantly higher than the V O_(2)max of the BE([48.0±5.4]mL⋅kg^(-1)⋅min^(-1),n=30)and similar to that of running.For clarifying the underlying mechanisms,a corresponding HIICE-protocol with BE and arm cranking ergometer exercise(AC)was used(sequence AC-AC-BE-AC-BE-AC-AC-BE).In some experiments,thigh blood flow was occluded by a cuff around the upper thigh.Without occlusion,the V O_(2) during the AC([39.2±7.1]mL⋅kg^(-1)⋅min^(-1)[6th bout])was significantly higher than the V O_(2)max of AC([30.2±4.4]mL⋅kg^(-1)⋅min^(-1),n=7).With occlusion,the corresponding V O_(2)([29.8±3.9]mL⋅kg^(-1)⋅min^(-1))was reduced to that of the V O_(2)max of AC and significantly less than the V O_(2) without occlusion.These findings suggest that during the last bouts of HIICE may exceed the of the specific exercise,probably because it is a summation of the V O_(2) for the ongoing exercise plus excess post-oxygen consumption(EPOC)produced by the previous exercise with a higher V O_(2)max.
