Eleven evaluating parameters for rice core collection were assessed based on genotypic values and molecular marke' information. Monte Carlo simulation combined with mixed linear model was used to eliminate the interf...Eleven evaluating parameters for rice core collection were assessed based on genotypic values and molecular marke' information. Monte Carlo simulation combined with mixed linear model was used to eliminate the interference from environment in order to draw more reliable results. The coincidence rate of range (CR) was the optimal parameter. Mean Simpson index (MD), mean Shannon-Weaver index of genetic diversity (M1) and mean polymorphism information content (MPIC) were important evaluating parameters. The variable rate of coefficient of variation (VR) could act as an important reference parameter for evaluating the variation degree of core collection. Percentage of polymorphic loci (p) could be used as a determination parameter for the size of core collection. Mean difference percentage (MD) was a determination parameter for the reliability judgment of core collection. The effective evaluating parameters for core collection selected in the research could be used as criteria for sampling percentage in different plant germplasm populations.展开更多
A powerful investigative tool in biology is to consider not a single mathematical model but a collection of models designed to explore different working hypotheses and select the best model in that collection.In these...A powerful investigative tool in biology is to consider not a single mathematical model but a collection of models designed to explore different working hypotheses and select the best model in that collection.In these lecture notes,the usual workflow of the use of mathematical models to investigate a biological problem is described and the use of a collection of model is motivated.Models depend on parameters that must be estimated using observations;and when a collection of models is considered,the best model has then to be identified based on available observations.Hence,model calibration and selection,which are intrinsically linked,are essential steps of the workflow.Here,some procedures for model calibration and a criterion,the Akaike Information Criterion,of model selection based on experimental data are described.Rough derivation,practical technique of computation and use of this criterion are detailed.展开更多
Collective computation is the process by which groups store and share information to arrive at decisions for collective behavior.How societies engage in effective collective computation depends partly on their scale.S...Collective computation is the process by which groups store and share information to arrive at decisions for collective behavior.How societies engage in effective collective computation depends partly on their scale.Social arrangements and technologies that work for small-and mid-scale societies are inadequate for dealing effectively with the much larger communication loads that societies face during the growth in scale that is a hallmark of the Holocene.An important bottleneck for growth may be the development of systems for persistent recording of information(writing),and perhaps also the abstraction of money for generalizing exchange mechanisms.Building on Shin et al.,we identify a Scale Threshold to be crossed before societies can develop such systems,and an Information Threshold which,once crossed,allows more or less unlimited growth in scale.We introduce several additional articles in this special issue that elaborate or evaluate this Thresholds Model for particular types of societies or times and places in the world.展开更多
Web Service是目前研究界和产业界广泛关注的技术之一.随着Web Service的广泛应用,研究者们普遍认识到,服务的非功能属性,即服务质量(Quality of Service,QoS)是面向服务的应用能否成功的关键因素之一.因此,研究者们尝试从多个角度对Qo...Web Service是目前研究界和产业界广泛关注的技术之一.随着Web Service的广泛应用,研究者们普遍认识到,服务的非功能属性,即服务质量(Quality of Service,QoS)是面向服务的应用能否成功的关键因素之一.因此,研究者们尝试从多个角度对QoS相关问题展开了研究.然而,现有工作普遍关注基于QoS的动态服务选择和组装等上层应用技术,而对于如何获取、存储、度量QoS等基础支持技术研究较少,而这些基础性工作对QoS相关的研究工作具有显著的重要性.此外,不同应用领域对Web Service QoS的需求不尽相同,因此,需要有一套灵活的机制支持在QoS模型定义、QoS度量方法、QoS信息采集等方面体现出的领域特性.针对这个问题,文中提出了一个可扩展的Web Service QoS信息管理框架,详细分析了该框架涉及到的重要方法与核心技术,并给出了该框架在北京大学软件构件库系统中的设计决策和方案.最后,介绍了文中框架在一个863计划项目中的应用实例,该实例展示了用户根据其应用的领域需求对本框架进行扩展并进行Web Service QoS管理的方法,从而验证了本管理框架的可扩展性及实用性.展开更多
基金the National Natural Science Foundation of China (Grant No. 30270759) the Science and Technology Department of Zhejiang Province (Grant No. 2005C32001).
文摘Eleven evaluating parameters for rice core collection were assessed based on genotypic values and molecular marke' information. Monte Carlo simulation combined with mixed linear model was used to eliminate the interference from environment in order to draw more reliable results. The coincidence rate of range (CR) was the optimal parameter. Mean Simpson index (MD), mean Shannon-Weaver index of genetic diversity (M1) and mean polymorphism information content (MPIC) were important evaluating parameters. The variable rate of coefficient of variation (VR) could act as an important reference parameter for evaluating the variation degree of core collection. Percentage of polymorphic loci (p) could be used as a determination parameter for the size of core collection. Mean difference percentage (MD) was a determination parameter for the reliability judgment of core collection. The effective evaluating parameters for core collection selected in the research could be used as criteria for sampling percentage in different plant germplasm populations.
基金SP is supported by a Discovery Grant of the Natural Sciences and Engineering Research Council of Canada(RGOIN-2018-04967).
文摘A powerful investigative tool in biology is to consider not a single mathematical model but a collection of models designed to explore different working hypotheses and select the best model in that collection.In these lecture notes,the usual workflow of the use of mathematical models to investigate a biological problem is described and the use of a collection of model is motivated.Models depend on parameters that must be estimated using observations;and when a collection of models is considered,the best model has then to be identified based on available observations.Hence,model calibration and selection,which are intrinsically linked,are essential steps of the workflow.Here,some procedures for model calibration and a criterion,the Akaike Information Criterion,of model selection based on experimental data are described.Rough derivation,practical technique of computation and use of this criterion are detailed.
基金the National Science Foundation(No.SMA-1620462)T.A.Kohler further acknowledges support from the Cluster of Excellence ROOTS,EXC 2150the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation)under Germany’s Excellence Strategy.
文摘Collective computation is the process by which groups store and share information to arrive at decisions for collective behavior.How societies engage in effective collective computation depends partly on their scale.Social arrangements and technologies that work for small-and mid-scale societies are inadequate for dealing effectively with the much larger communication loads that societies face during the growth in scale that is a hallmark of the Holocene.An important bottleneck for growth may be the development of systems for persistent recording of information(writing),and perhaps also the abstraction of money for generalizing exchange mechanisms.Building on Shin et al.,we identify a Scale Threshold to be crossed before societies can develop such systems,and an Information Threshold which,once crossed,allows more or less unlimited growth in scale.We introduce several additional articles in this special issue that elaborate or evaluate this Thresholds Model for particular types of societies or times and places in the world.
文摘Web Service是目前研究界和产业界广泛关注的技术之一.随着Web Service的广泛应用,研究者们普遍认识到,服务的非功能属性,即服务质量(Quality of Service,QoS)是面向服务的应用能否成功的关键因素之一.因此,研究者们尝试从多个角度对QoS相关问题展开了研究.然而,现有工作普遍关注基于QoS的动态服务选择和组装等上层应用技术,而对于如何获取、存储、度量QoS等基础支持技术研究较少,而这些基础性工作对QoS相关的研究工作具有显著的重要性.此外,不同应用领域对Web Service QoS的需求不尽相同,因此,需要有一套灵活的机制支持在QoS模型定义、QoS度量方法、QoS信息采集等方面体现出的领域特性.针对这个问题,文中提出了一个可扩展的Web Service QoS信息管理框架,详细分析了该框架涉及到的重要方法与核心技术,并给出了该框架在北京大学软件构件库系统中的设计决策和方案.最后,介绍了文中框架在一个863计划项目中的应用实例,该实例展示了用户根据其应用的领域需求对本框架进行扩展并进行Web Service QoS管理的方法,从而验证了本管理框架的可扩展性及实用性.