目的探讨肿瘤放射治疗专业规培医师教学实践中引入LPCBL(lecture,problem and case based learning)联合MDT教学模式的效果。方法选取2016年9月—2019年11月在医院放疗科轮转的68名规培医师为研究对象。根据所提供的教学模式的不同,将2...目的探讨肿瘤放射治疗专业规培医师教学实践中引入LPCBL(lecture,problem and case based learning)联合MDT教学模式的效果。方法选取2016年9月—2019年11月在医院放疗科轮转的68名规培医师为研究对象。根据所提供的教学模式的不同,将2016年9月—2017年8月的19名规培医师归为对照组(常规教学组),2017年9月—2019年11月的49名规培医师归为试验组(LPCBL+MDT教学组)。从教学效果(标准化考试成绩)及教学满意度(问卷调查)两方面做比较分析。结果在放疗基础理论成绩、放疗病例分析成绩及放疗靶区勾画成绩等方面,试验组规培医师对比对照组均具有优势,两组差异有统计学意义(P<0.05);在带教老师满意度、学习动力与兴趣、理论知识掌握度、临床思维能力及临床协作能力等方面,试验组规培医师对比对照组均具有优势,两组差异有统计学意义(P<0.05)。结论将LPCBL联合MDT教学模式引入肿瘤放疗专业规培医师教学实践中,有利于提高教学效果及满意度。展开更多
Extragonadal primary yolk sac tumor of the intestinal tract origin is exceedingly rare. Through a multiple disciplinary team, the diagnosis and treatment of primary intestinal yolk sac tumor were further defined. We r...Extragonadal primary yolk sac tumor of the intestinal tract origin is exceedingly rare. Through a multiple disciplinary team, the diagnosis and treatment of primary intestinal yolk sac tumor were further defined. We report 2 such cases with detailed histologic and immunohistochemical analysis. The two patients were a 7-year-old girl and a 29-year-old woman. Both of them preoperatively had an elevated serum alpha fetoprotein(AFP) level(≥ 1,210 ng/mL). The tumors are located in the intestine and imaging examination indicated the rectum as the primary site. Grossly the mass was grey-white and crisp texture. Microscopic examination featured reticular, microcystic, macrocystic, papillary, solid, and some glandular patterns. Immunohistochemically,tumor cells of both cases were positive for SALL4, AFP, pan-cytokeratin(AE1/AE3), and glypican-3. Simultaneously, a stain for EMA, OCT4, CD30, HCG, vimentin and CK20 were negative in all 2 neoplasms. The features of morphology,immunohistochemistry, laboratory examinations and imaging studies consist of the diagnosis of primary yolk sac tumor of the intestine.展开更多
文摘目的探讨肿瘤放射治疗专业规培医师教学实践中引入LPCBL(lecture,problem and case based learning)联合MDT教学模式的效果。方法选取2016年9月—2019年11月在医院放疗科轮转的68名规培医师为研究对象。根据所提供的教学模式的不同,将2016年9月—2017年8月的19名规培医师归为对照组(常规教学组),2017年9月—2019年11月的49名规培医师归为试验组(LPCBL+MDT教学组)。从教学效果(标准化考试成绩)及教学满意度(问卷调查)两方面做比较分析。结果在放疗基础理论成绩、放疗病例分析成绩及放疗靶区勾画成绩等方面,试验组规培医师对比对照组均具有优势,两组差异有统计学意义(P<0.05);在带教老师满意度、学习动力与兴趣、理论知识掌握度、临床思维能力及临床协作能力等方面,试验组规培医师对比对照组均具有优势,两组差异有统计学意义(P<0.05)。结论将LPCBL联合MDT教学模式引入肿瘤放疗专业规培医师教学实践中,有利于提高教学效果及满意度。
基金supported by Tianjin Municipal Health Bureau Science and Technology Foundation(Grant No.16KG125)National Clinical Research Center for Cancer
文摘Extragonadal primary yolk sac tumor of the intestinal tract origin is exceedingly rare. Through a multiple disciplinary team, the diagnosis and treatment of primary intestinal yolk sac tumor were further defined. We report 2 such cases with detailed histologic and immunohistochemical analysis. The two patients were a 7-year-old girl and a 29-year-old woman. Both of them preoperatively had an elevated serum alpha fetoprotein(AFP) level(≥ 1,210 ng/mL). The tumors are located in the intestine and imaging examination indicated the rectum as the primary site. Grossly the mass was grey-white and crisp texture. Microscopic examination featured reticular, microcystic, macrocystic, papillary, solid, and some glandular patterns. Immunohistochemically,tumor cells of both cases were positive for SALL4, AFP, pan-cytokeratin(AE1/AE3), and glypican-3. Simultaneously, a stain for EMA, OCT4, CD30, HCG, vimentin and CK20 were negative in all 2 neoplasms. The features of morphology,immunohistochemistry, laboratory examinations and imaging studies consist of the diagnosis of primary yolk sac tumor of the intestine.
