A Simple Method for Source Depth Estimation with Multi-path Time Delay in Deep Ocean

A method of source depth estimation based on the multi-path time delay difference is proposed. When the minimum time arrivals in all receiver depths are snapped to a certain time on time delay-depth plane, time delay arrivals of surface-bottom reflection and bottom-surface reflection intersect at the source depth. Two hydrophones deployed vertically with a certain interval are required at least. If the receiver depths are known, the pair of time delays can be used to estimate the source depth. With the proposed method the source depth can be estimated successfully in a moderate range in the deep ocean without complicated matched-field calculations in the simulations and experiments.

Prescribed Performance Tracking Control of Time-Delay Nonlinear Systems With Output Constraints

The problem of prescribed performance tracking control for unknown time-delay nonlinear systems subject to output constraints is dealt with in this paper. In contrast with related works, only the most fundamental requirements, i.e., boundedness and the local Lipschitz condition, are assumed for the allowable time delays. Moreover, we focus on the case where the reference is unknown beforehand, which renders the standard prescribed performance control designs under output constraints infeasible. To conquer these challenges, a novel robust prescribed performance control approach is put forward in this paper.Herein, a reverse tuning function is skillfully constructed and automatically generates a performance envelop for the tracking error. In addition, a unified performance analysis framework based on proof by contradiction and the barrier function is established to reveal the inherent robustness of the control system against the time delays. It turns out that the system output tracks the reference with a preassigned settling time and good accuracy,without constraint violations. A comparative simulation on a two-stage chemical reactor is carried out to illustrate the above theoretical findings.

Attosecond ionization time delays in strong-field physics

Electronic processes within atoms and molecules reside on the timescale of attoseconds. Recent advances in the laserbased pump-probe interrogation techniques have made possible the temporal resolution of ultrafast electronic processes on the attosecond timescale, including photoionization and tunneling ionization. These interrogation techniques include the attosecond streak camera, the reconstruction of attosecond beating by interference of two-photon transitions, and the attoclock. While the former two are usually employed to study photoionization processes, the latter is typically used to investigate tunneling ionization. In this review, we briefly overview these timing techniques towards an attosecond temporal resolution of ionization processes in atoms and molecules under intense laser fields. In particular, we review the backpropagation method, which is a novel hybrid quantum-classical approach towards the full characterization of tunneling ionization dynamics. Continued advances in the interrogation techniques promise to pave the pathway towards the exploration of ever faster dynamical processes on an ever shorter timescale.

A nonlocal dispersal and time delayed HIV infection model with general incidences

Biologically,because of the impact of reproduction period and nonlocal dispersal of HIV-infected cells,time delay and spatial heterogeneity should be considered.In this paper,we establish an HIV infection model with nonlocal dispersal and infection age.Moreover,applying the theory of Fourier transformation and von Foerster rule,we transform the model to an integrodifferential equation with nonlocal time delay and dispersal.The well-posedness,positivity,and boundedness of the solution for the model are studied.

Research on the Damping Mechanism of Time-Delay Coupled Negative Stiffness Dynamic Absorber in Nonlinear Vibration Damping System

A study was conducted on the effect of time delay and structural parameters on the vibration reduction of a time delayed coupled negative stiffness dynamic absorber in nonlinear vibration reduction systems. Taking dynamic absorbers with different structural and control parameters as examples, the effects of third-order nonlinear coefficients, time-delay control parameters, and negative stiffness coefficients on reducing the replication of the main system were discussed. The nonlinear dynamic absorber has a very good vibration reduction effect at the resonance point of the main system and a nearby area, and when 1 increases to a certain level, the stable region of the system continues to increase. The amplitude curve of the main system of a nonlinear dynamic absorber will generate Hop bifurcation and saddle node bifurcation in the region far from the resonance point, resulting in almost periodic motion and jumping phenomena in the system. For nonlinear dynamic absorbers with determined structural parameters, time-delay feedback control can be adopted to control the amplitude of the main system. For different negative stiffness coefficients, there exists a minimum damping point for the amplitude of the main system under the determined system structural parameters and time-delay feedback control parameters.

Refinement of the Proposed Gamma-Ray Burst Time Delay Model

This paper is the second instalment in our study of the observed time delay in the arrival times of radio photons emanating from Gamma Ray Bursts (GRBs). The mundane assumption in contemporary physics as to the cause of these pondersome time delays is that they are a result of the photon being endowed with a non-zero mass. While we do not rule out the possibility of a non-zero mass for the photon, our working assumption is that the major cause of these time delays may very well be that these photons are travelling in a rarefied cosmic plasma in which the medium’s electrons interact with the electric component of the Photon, thus generating tiny currents that lead to dispersion, hence, a frequency-dependent speed of Light (FDSL). In the present instalment, we “improve” on the model presented in the first instalment by dropping the assumption that the resultant pairs of these radio photons leave the shock front simultaneously. The new assumption of a non-simultaneous— albeit systematic—emission of these photon pairs allows us to obtain a much more convincing and stronger correlation in the time delay. This new correlation allows us to build a unified model for the four GRBs in our sample using a relative distance correction mechanism. The new unified model allows us to obtain as our most significant result a value for the frequency equivalence of the interstellar medium (ISM)’s conductance ν* ~ 1.500 ± 0.009 Hzand also an independent distance measure to the GRBs where we obtain for our four GRB samples an average distance of: ~69.40 ± 0.10, 40.00 ± 0.00, 58.40 ± 0.40, and 86.00 ± 1.00 Mpc, for GRB 030329, 980425, 000418 and 021004 respectively.

Associate factors for endoscopic submucosal dissection operation time and postoperative delayed hemorrhage of early gastric cancer

BACKGROUND Endoscopic submucosal dissection(ESD)is a treatment for early gastric cancer with the advantages of small invasion,fewer complications,and a low local recurrence rate.However,there is a high risk of complications such as bleeding and perforation,and the operation time is also longer.ESD operation time is closely related to bleeding and perforation.AIM To investigate the influencing factors associated with ESD operation time and postoperative delayed hemorrhage to provide a reference for early planning,early identification,and prevention of complications.METHODS We conducted a retrospective study based on the clinical data of 520 patients with early gastric cancer in the Second Affiliated Hospital of Hainan Medical University from January 2019 to December 2021.The baseline data,clinical features,and endoscopic and pathological characteristics of patients were collected.The multivariate linear regression model was used to investigate the influencing factors of ESD operation time.Logistic regression analysis was carried out to evaluate the influencing factors of postoperative delayed hemorrhage.RESULTS The multivariate analysis of ESD operation time showed that the maximum lesion diameter could affect 8.815%of ESD operation time when other influencing factors remained unchanged.The operation time increased by 3.766%or 10.247%if the lesion was mixed or concave.The operation time increased by 4.417%if combined with an ulcer or scar.The operation time increased by 3.692%if combined with perforation.If infiltrated into the submucosa,it increased by 2.536%.Multivariate analysis of delayed hemorrhage after ESD showed that the maximum diameter of the lesion,lesion morphology,and ESD operation time were independent influencing factors for delayed hemorrhage after ESD.Patients with lesion≥3.0 cm(OR=3.785,95%CI:1.165-4.277),lesion morphology-concave(OR=10.985,95%CI:2.133-35.381),and ESD operation time≥60 min(OR=2.958,95%CI:1.117-3.526)were prone to delayed hemorrhage after ESD.CONCLUSION If the maximum diameter of the lesion in patients with early gastric cancer is≥3.0 cm,and the shape of the lesion is concave,or accompanied by an ulcer or scar,combined with perforation,and infiltrates into the submucosa,the ESD operation will take a longer time.When the maximum diameter of the lesion is≥3.0 cm,the shape of the lesion is concave in patients and the operation time of ESD takes longer time,the risk of delayed hemorrhage after ESD is higher.

Whole-brain CT Perfusion at Admission and During Delayed Time-window Detects the Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage

Objective To evaluate the utility of computed tomography perfusion(CTP)both at admission and during delayed cerebral ischemia time-window(DCITW)in the detection of delayed cerebral ischemia(DCI)and the change in CTP parameters from admission to DCITW following aneurysmal subarachnoid hemorrhage.Methods Eighty patients underwent CTP at admission and during DCITW.The mean and extreme values of all CTP parameters at admission and during DCITW were compared between the DCI group and non-DCI group,and comparisons were also made between admission and DCITW within each group.The qualitative color-coded perfusion maps were recorded.Finally,the relationship between CTP parameters and DCI was assessed by receiver operating characteristic(ROC)analyses.Results With the exception of cerebral blood volume(P=0.295,admission;P=0.682,DCITW),there were significant differences in the mean quantitative CTP parameters between DCI and non-DCI patients both at admission and during DCITW.In the DCI group,the extreme parameters were significantly different between admission and DCITW.The DCI group also showed a deteriorative trend in the qualitative color-coded perfusion maps.For the detection of DCI,mean transit time to the center of the impulse response function(Tmax)at admission and mean time to start(TTS)during DCITW had the largest area under curve(AUC),0.698 and 0.789,respectively.Conclusion Whole-brain CTP can predict the occurrence of DCI at admission and diagnose DCI during DCITW.The extreme quantitative parameters and qualitative color-coded perfusion maps can better reflect the perfusion changes of patients with DCI from admission to DCITW.

Synchronization of stochastic complex networks with time-delayed coupling

Noise and time delay are inevitable in real-world networks. In this article, the framework of master stability function is generalized to stochastic complex networks with time-delayed coupling. The focus is on the effects of noise, time delay,and their inner interactions on the network synchronization. It is found that when there exists time-delayed coupling in the network and noise diffuses through all state variables of nodes, appropriately increasing the noise intensity can effectively improve the network synchronizability;otherwise, noise can be either beneficial or harmful. For stochastic networks, large time delays will lead to desynchronization. These findings provide valuable references for designing optimal complex networks in practical applications.

Hopf bifurcation and phase synchronization in memristor-coupled Hindmarsh–Rose and FitzHugh–Nagumo neurons with two time delays

A memristor-coupled heterogenous neural network consisting of two-dimensional(2D)FitzHugh–Nagumo(FHN)and Hindmarsh–Rose(HR)neurons with two time delays is established.Taking the time delays as the control parameters,the existence of Hopf bifurcation near the stable equilibrium point in four cases is derived theoretically,and the validity of the Hopf bifurcation condition is verified by numerical analysis.The results show that the two time delays can make the stable equilibrium point unstable,thus leading to periodic oscillations induced by Hopf bifurcation.Furthermore,the time delays in FHN and HR neurons have different effects on the firing activity of neural network.Complex firing patterns,such as quiescent state,chaotic spiking,and periodic spiking can be induced by the time delay in FHN neuron,while the neural network only exhibits quiescent state and periodic spiking with the change of the time delay in HR neuron.Especially,phase synchronization between the heterogeneous neurons is explored,and the results show that the time delay in HR neurons has a greater effect on blocking the synchronization than the time delay in FHN neuron.Finally,the theoretical analysis is verified by circuit simulations.

A True-Time-Delay Array Architecture for Wideband Multi-Beam Tracking

The true-time delay(TTD)units are critical for solving beam squint and frequency selective fading inWideband Large-Scale Antenna Systems(LSASs).In this work,we propose a TTD array architecture for wideband multi-beam tracking that eliminates the beam squint phenomenon and filters out interference signals by applying a spatial filter and time delay estimations(TDEs).The paper presents a novel approach to spatial filter design by introducing a transformation matrix that can optimize the beam response in a specific direction and at a specific frequency.Using the variable fractional delay(VFD)filters,we propose a TDE algorithm with a Newton-Raphson iteration update process that corrects the arrival time delay difference between sensors.Simulations and examples have demonstrated that the proposed architecture can achieve beam tracking within 10 ms at the low signalto-noise ratio(SNR)and demodulation loss is less than 0.5 dB in wideband multi-beam scenarios.

An improved ISR-WV rumor propagation model based on multichannels with time delay and pulse vaccination

The rapid development of the Internet has broadened the channels of dissemination of information,it has also led to the rapid and widespread propagation of rumors,which can have a serious negative impact socially.In this paper,an improved ISR-WV rumor propagation model integrating multichannels is proposed by considering the system’s time delay,and the influence of different channels of propagation on the dynamic process is further analyzed.Moreover,the basic reproduction number R0,rumor-free equilibrium,and rumor-prevailing equilibrium,as well as their stability,are deduced.Then,an optimal control problem with pulse vaccination is designed.Finally,the validity of the model and theoretical results is verified by numerical simulations and a practical application.The results show that the rumor propagation threshold R0 is more sensitive to the rate of the propagation of the information base channel.The shorter the thinking timeτ_(1)required for the ignorant to react after obtaining the information,the larger the final scale of propagation.Under this condition,the time delayτ_(2)spent by a spreader in producing a video is negatively related to the final scale of the propagation;conversely,a longerτ_(1)implies that the person tends to more cognizant,which can suppress the spread of rumors.Under this condition,τ_(2)has little effect on the final scale of propagation.In addition,the results also prove that timely implementation of the pulse vaccination control strategy of popular science education can effectively control the propagation of rumors and reduce their negative impact.

High-Precision Time Delay Estimation Based on Closed-Form Offset Compensation

To improve the estimation accuracy,a novel time delay estimation(TDE)method based on the closed-form offset compensation is proposed.Firstly,we use the generalized cross-correlation with phase transform(GCC-PHAT)method to obtain the initial TDE.Secondly,a signal model using normalized cross spectrum is established,and the noise subspace is extracted by eigenvalue decomposition(EVD)of covariance matrix.Using the orthogonal relation between the steering vector and the noise subspace,the first-order Taylor expansion is carried out on the steering vector reconstructed by the initial TDE.Finally,the offsets are compensated via simple least squares(LS).Compared to other state-of-the-art methods,the proposed method significantly reduces the computational complexity and achieves better estimation performance.Experiments on both simulation and real-world data verify the efficiency of the proposed approach.

Exact Solutions and Finite Time Stability of Linear Conformable Fractional Systems with Pure Delay

We study nonhomogeneous systems of linear conformable fractional differential equations with pure delay.By using new conformable delayed matrix functions and the method of variation,we obtain a representation of their solutions.As an application,we derive a finite time stability result using the representation of solutions and a norm estimation of the conformable delayedmatrix functions.The obtained results are new,and they extend and improve some existing ones.Finally,an example is presented to illustrate the validity of our theoretical results.

Critical dispersion of chirped fiber Bragg grating for eliminating time delay signature of distributed feedback laser chaos

Optical chaos has attracted widespread attention owing to its complex dynamic behaviors.However,the time delay signature(TDS)caused by the external cavity mode reduces the complexity of optical chaos.We propose and numerically demonstrate the critical dispersion of chirped fiber Bragg grating(CFBG)for eliminating the TDS of laser chaos in this work.The critical dispersion,as a function of relaxation frequency and bandwidth of the optical spectrum,is found through extensive dynamics simulations.It is shown that the TDS can be eliminated when the dispersion of CFBG is above this critical dispersion.In addition,the influence of dispersive feedback light and output light from a laser is investigated.These results provide important quantitative guidance for designing chaotic semiconductor lasers without TDS.

Time Delay Estimation in Radar System using Fuzzy Based Iterative Unscented Kalman Filter

RSs(Radar Systems)identify and trace targets and are commonly employed in applications like air traffic control and remote sensing.They are necessary for monitoring precise target trajectories.Estimations of RSs are non-linear as the parameters TDEs(time delay Estimations)and Doppler shifts are computed on receipt of echoes where EKFs(Extended Kalman Filters)and UKFs(Unscented Kalman Filters)have not been examined for computations.RSs,certain times result in poor accuracies and SNRs(low signal to noise ratios)especially,while encountering complicated environments.This work proposes IUKFs(Iterated UKFs)to track onlinefilter performances while using optimization techniques to enhance outcomes.The use of cost functions can assist state corrections while lowering costs.A new parameter is optimized using MCEHOs(Mutation Chaotic Elephant Herding Optimizations)by linearly approximating system non-linearity where OIUKFs(Optimized Iterative UKFs)predict a target's unknown parameters.To obtain optimal solutions theoretically,OIUKFs take less iteration,resulting in shorter execution times.The proposed OIUKFs provide numerical approximations which are derivative-free implementations.Simulation evaluation results with estimators show better performances in terms of reduced NMSEs(Normalized Mean Square Errors),RMSEs(Root Mean Squared Errors),SNRs,variances,and better accuracies than current approaches.

Tumor-Immune Interaction System with the Effect of Time Delay and Hyperglycemia on the Breast Cancer Cells

Breast cancer in women is a complicated and multifaceted disease. Studies have demonstrated that hyperglycemia is one of the most significant risk factors for breast cancer. Hyperglycemia is when the sugar level in human blood is too high, which means excess glucose. Glucose excess can encourage the growth, invasion, and migration of breast cancer cells at the cellular level. Though, the effects of glucose on the dynamics of breast cancer cells have been examined mathematically by a system of ordinary differential equations. However, the non-instantaneous biological occurrences leading to the secretion of immuno-suppressive cytokines by tumors to evade immune surveillance and the immune cells’ derivation of cytokines to attack the tumor cells are not yet discussed. Therefore, investigating the biological process involved in the dynamics of tumors, immune and normal cells with excessive glucose concentration is inviolable to determining the best procedure for controlling tumors’ uncontrollable growth. Time delay, denoted by τ, is used to describe the time tumor cells take to secrete immunosuppressive cytokines to evade immune surveillance and the time immune cells take to recognize and attack the tumor cells. We have studied the local stability analysis of the biological steady states in both delayed and non-delayed system. The Routh-Hurwitz stability criterion is used to analyze the dynamical equilibrium of the cells’ population. Hopf bifurcation was analyzed by using time delay s as a bifurcation parameter. The analytical results suggest an unstable scenario for a tumor-free equilibrium point as normal cells are bound to grow to their carrying capacity. The result predicts a stable system for coexisting equilibrium when the interaction is instantaneous (τ = 0). However, when τ > 0, the coexisting equilibrium point switches from stable to unstable. The numerical results not only validate all the analytical results but also show the case of possible situations when glucose concentration is varied, indicating that both tumor growth and immune system efficiency are highly affected by the level of glucose in the blood. This concluded that the delay in the secretion of cytokines by immune cells and derivation cytokines by the tumors helps to identify the possible chaotic situation under different glucose concentration and the extent to which such delay can have on restoration of the normal cells when glucose concentration is low.

Designing Proportional-Integral Consensus Protocols for Second-Order Multi-Agent Systems Using Delayed and Memorized State Information

This paper is concerned with consensus of a secondorder linear time-invariant multi-agent system in the situation that there exists a communication delay among the agents in the network.A proportional-integral consensus protocol is designed by using delayed and memorized state information.Under the proportional-integral consensus protocol,the consensus problem of the multi-agent system is transformed into the problem of asymptotic stability of the corresponding linear time-invariant time-delay system.Note that the location of the eigenvalues of the corresponding characteristic function of the linear time-invariant time-delay system not only determines the stability of the system,but also plays a critical role in the dynamic performance of the system.In this paper,based on recent results on the distribution of roots of quasi-polynomials,several necessary conditions for Hurwitz stability for a class of quasi-polynomials are first derived.Then allowable regions of consensus protocol parameters are estimated.Some necessary and sufficient conditions for determining effective protocol parameters are provided.The designed protocol can achieve consensus and improve the dynamic performance of the second-order multi-agent system.Moreover,the effects of delays on consensus of systems of harmonic oscillators/double integrators under proportional-integral consensus protocols are investigated.Furthermore,some results on proportional-integral consensus are derived for a class of high-order linear time-invariant multi-agent systems.

Turing Instability of Gray-Scott Reaction-Diffusion Model with Time Delay Effects

The reaction diffusion Gray-Scott model with time delay is put forward with the assumption of Neumann boundary condition is satisfied. Based on the Turing bifurcation condition, the Turing curves on two parameter plane are discussed without time delay. The normal form is computed via applying Lyapunov-Schmidt reduction method in system of PDE, and the bifurcating direction of pitchfork bifurcation underlying codimension-1 singularity of Turing point is computed. The continuation of Pitchfork bifurcation is simulated with varying free parameter continuously near the turing point, which is in coincidence with the theoritical analysis results. The wave pattern formation in the case of turing instability is also simulated which discover Turing oscillation phenomena from periodicity to irregularity.

Diagnostic delay in inflammatory bowel diseases in a German population

BACKGROUND Early diagnosis is key to prevent bowel damage in inflammatory bowel disease(IBD).Risk factor analyses linked with delayed diagnosis in European IBD patients are scarce and no data in German IBD patients exists.AIM To identify risk factors leading to prolonged diagnostic time in a German IBD cohort.METHODS Between 2012 and 2022,430 IBD patients from four Berlin hospitals were enrolled in a prospective study and asked to complete a 16-item questionnaire to determine features of the path leading to IBD diagnosis.Total diagnostic time was defined as the time from symptom onset to consulting a physician(patient waiting time)and from first consultation to IBD diagnosis(physician diagnostic time).Univariate and multivariate analyses were performed to identify risk factors for each time period.RESULTS The total diagnostic time was significantly longer in Crohn’s disease(CD)compared to ulcerative colitis(UC)patients(12.0 vs 4.0 mo;P<0.001),mainly due to increased physician diagnostic time(5.5 vs 1.0 mo;P<0.001).In a multivariate analysis,the predominant symptoms diarrhea(P=0.012)and skin lesions(P=0.028)as well as performed gastroscopy(P=0.042)were associated with longer physician diagnostic time in CD patients.In UC,fever was correlated(P=0.020)with shorter physician diagnostic time,while fatigue(P=0.011)and positive family history(P=0.046)were correlated with longer physician diagnostic time.CONCLUSION We demonstrated that CD patients compared to UC are at risk of long diagnostic delay.Future efforts should focus on shortening the diagnostic delay for a better outcome in these patients.