Comparison of the Imaging Manifestations and Diagnostic Values of Multi-slice Spiral CT and Enhanced MRI Scans of Primary Liver Cancer(PLC)Intrahepatic Lesions

Objective:To compare and analyze the clinical diagnostic value of multi-slice spiral CT and enhanced MRI for primary liver cancer(PLC),and to summarize the imaging findings.Methods:The research subjects in this article were 50 patients with PLC who were admitted to our hospital from 2017 April to 2018 September.After the patients were admitted,they were examined by multi-slice spiral CT and enhanced MRI scanning,and the pathological diagnosis results were followed up.Relevant information was reviewed and analyzed.Results:The detection rate of multi-slice spiral CT was higher than that of MRI in the portal venous phase lesion detection.The difference was statistically significant(P<0.05).The detection rate of lesions in the arterial phase and delayed phase was not statistically significant(P>0.05);the diagnostic accuracy of multi-slice spiral CT was 85.96%,and the diagnostic accuracy of enhanced MRI scanning was 91.11%,which was not statistically significant(P>0.05).MRI scans showed the capsules of primary liver cancer better than CT,but the difference was not statistically significant(P>0.05).Conclusion:In conclusion,both multi-slice spiral CT and enhanced MRI can be used for the effective diagnosis of primary liver cancer intrahepatic lesions.The diagnostic value of the two is equivalent,but enhanced MRI has a slightly higher diagnostic accuracy and can be used as the preferred method.

Three-dimensional Imaging of Multi-slice Spiral CT in Bronchial Artery Correlative Study on Blood Supply of Central Lung Cancer and Its Clinical Significance

Objective: To evaluate three-dimensional bronchial artery imaging charactersin central lung cancer and applied values with multi-slice spiral CT (MSCT) to provide theoreticalevidence on blood supply and intervention therapy. Methods: Eighteen patients with central lungcancer underwent MSCT with real time helical thin-slice CT scanning. Three-dimensional bronchialartery reconstruction was done at the console work-station. The space anatomical characters ofbronchial artery were observed through different rotations. Results: For 6 cases, thethree-dimensional images of bronchial artery (33.33%) could exactly show the origins, the routes(lung inner segment and mediatism segment) and the diameters of bronchial arteries. Vision rate ofbronchial arteries was the highest in pulmonary artery stricture and truncation groups, and thevessels' diameter became larger apparently. These characters demonstrated blood supply of this kindof central lung cancer come from bronchial artery. Volume rendering images were the best ones amongthree-dimensional images. Conclusion: Three-dimensional imaging with MSCT in bronchial artery canreveal the anatomical characters of bronchial artery and provide theoretical evidence on bloodsupply and intervention therapy of central lung cancer.

Using receiver operating characteristic curves to evaluate the diagnostic value of the combination of multislice spiral CT and alpha-fetoprotein levels for small hepatocellular carcinoma in cirrhotic patients

BACKGROUND： The various combination of multiphase enhancement multislice spiral CT （MSCT） makes the diagno- sis of a small hepatocellular carcinoma （sHCC） on the back- ground of liver cirrhosis possible. This study was to explore whether the combination of MSCT enhancement scan and alpha-fetoprotein （AFP） level ficiency for sHCC. could increase the diagnostic ef- METHODS： This study included 35 sHCC patients and 52 cir- rhotic patients without image evidence of HCC as a control group. The diagnoses were made by three radiologists em- ploying a 5-point rating scale, with postoperative pathologic results as the gold standard. Receiver operating characteristic （ROC） curve analysis was performed to evaluate the diag- nostic value of the three MSCT combination modes （arterial phase＋portal-venous phase, arterial phase＋delayed phase, arterial phase＋portal-venous phase＋delayed phase） and AFP levels for sHCC on the background of liver cirrhosis. RESULTS： The area under ROC curve （AUC）, sensitivity, and specificity of the combination of arterial phase＋portal- venous phase＋delayed phase were 0.93, 93%, and 82%, respectively. The average AUC of the arterial phase＋portal- venous phase＋delayed phase combination was significantly greater than that of the arterial phase＋portal-venous phase （AUC=0.84, P=0.01） and arterial phase＋delayed phase （AUC=0.85, P=0.03）. Arterial phase＋portal-venous phase had a smaller AUC （0.84） than arterial phase＋delayed phase （0.85）, but the difference was insignificant （P=0.15）. After combining MSCT enhancement scan with AFP, the AUC, sensitivity, and specificity were 0.95, 94%, and 83%, respectively, indicating a greatly increased diagnostic efficiency for sHCC. CONCLUSIONS： The combination of AFP and 3 phases MSCT enhancement scan could increase the diagnostic efficiency for sHCC on the background of liver cirrhosis. The application of ROC curve analysis has provided a new method and reference in HCC diagnosis.

Multi-slice spiral CT angiography in evaluating donors of living-related liver transplantation

BACKGROUND: During the past years, the number of liver transplantation has increased greatly, but the number of available organs has not increased. In view of the critical shortage of organs, the indications for living-related liver transplantation (LRLT) have broadened since experience with the procedure has been achieved. This study was undertaken to assess the value of multi-slice spiral CT (MSCT) angiography in evaluating the hepatic arterial and veinous anatomy of potential donors for LRLT. METHODS: MSCT was performed after intravenous injection of contrast material at 3 ml/s. The total dose was calculated as 2 ml/kg. Twenty LRLT donors (2 men and 18 women) were subjected to MSCT angiography of hepatic blood vessels. These were generated by volume rendering and maximum intensity projection, while curved planar reformation was added in 5 patients. RESULTS: We identified 10 important hepatic vascular variants in 9 of the 20 donors (4 arterial, 4 venous, and 2 portal venous variants). In hepatic arterial variants, two had a replaced right hepatic artery arising from the superior mesenteric artery, an accessory right hepatic artery from the superior mesenteric artery and a replaced left hepatic artery arising from the left gastric artery. In hepatic venous variants, three had an accessory inferior right hepatic vein and one had two accessory inferior right hepatic veins. In hepatic portal venous variants, two had trifurcation of the main portal vein. CONCLUSIONS: As a non-invasive and reliable method, MSCT angiography is of value in the clinical evaluation of LRLT donors. MSCT angiography should be recommended as a routine preoperative examination for potential LRLT donors.

Diagnostic value of multi-slice spiral CT in aortic dissection

Background Aortic dissection occurs at a low incidence, but is associated with high mortality. It is generally acute onset, complicated and is often misdiagnosed; therefore is a macro vascular disease that poses major threat on patients’ lives. Timely diagnosis and management are essential, so we investigated the diagnostic value of multi-slice spiral CT in aortic dissection. Methods clinical data from 21 patients with confirmed aortic dissection were retrospectively analyzed. All patients had undergone plain and contrasted multi-slice spiral CT scans. Results true lumen and pseudo cavity were clearly revealed in all 21 patients, of which 17 showed intimal flap, four showed intimal calcification and inward displacement, while 2 had thrombosis in the pseudo cavity. As for classification among these 21 patients, 9 had type Ⅰ aortic dissection, including two patients with innominate artery involvement, 1 with celiac trunk involvement and 2 with left renal artery involvement; 2 had type Ⅱ aortic dissection, including 1 patient with innominate artery involvement; Another ten patients had type III aortic dissection, including 2 patients with left subclavian artery involvement and 1 with celiac trunk involvement. Nineteen out of 21 patients had clearly revealed initial rupture. Conclusion multi-slice spiral CT is characterized by rapidness, non-invasiveness and accuracy. It provides clear visualization of the location and scope of aortic dissection, location of the rupture as well as the valves, which makes it a first-choice imaging approach for the diagnosis of aortic dissection.

Study on the combined value of multi-slice spiral CT in the diagnosis of elderly colorectal cancer colorectal cancer tumor markers

Objective:To investigate the value of tumor markers in colorectal cancer with multi-slice spiral CT in the diagnosis of elderly colorectal cancer.Methods:From January 2016 to September 2017 year period, 73 elderly patients with colorectal cancer treated in our hospital were selected as observation group;64 elderly patients with intestinal benign lesions were selected as control group during the same period. Serum samples were collected to detect contents of CEA, CA72-4, CA19-9 and CYFRA21-1 by Roche luminous immunoassay analyzer, and multi slice spiral CT was used.Results:Serum levels of CEA, CA72-4, CA19-9 and CYFRA21-1 levels of the observation group were significantly higher than that of the control group;the positive rate of CEA, CA72-4, CA19-9, CYFRA21-1 and their combined detection were all significantly higher than that of the control group;positive rate of MSCT in the observation group was higher than the control group;positive rates of tumor markers combining with MSCT examination of colorectal cancer were higher than that of combined detection of tumor markers and MSCT examination;but there was no significant difference in positive rate of combined detection of tumor markers and the positive rate of MSCT detection of colorectal cancer.Conclusion:Colorectal cancer tumor markers combined with multi-slice spiral CT in the diagnosis of colorectal cancer in elderly has important research value, can significantly improve the positive rate of diagnosis.

Value of Multi-slice Spiral CT in the Diagnosis and Resectability of Pancreatic Cancer

Objective:To analyze the value of multislice spiral CT in the diagnosis and resectability of pancreatic cancer.Method:56 patients with pancreatic cancer treated in our hospital from January 2018 to October 2019 were selected as the research subjects.All patients underwent multi-phase scanning by multislice spiral CT.According to the results of the images,observe whether the pancreatic cancer has affected the blood vessels surrounding the pancreas,evaluate the resectability based on the results of the examination,and analyze the final results of the operation which was taken as the standard.Results:all the 56 cases presented slightly low density or equal density,and 28 cases had complete outline.Multi-slice spiral assessment of patients’vascular invasion types found that 192 branches can be resected with 70 branches cannot;Multi-slice spiral assessment of the main arterial and venous invasion grades around the pancreas of the patients found that 212 branches can be resected with 50 branches cannot;Multi-slice spiral CT was used to evaluate the resectability of pancreatic cancer compared with surgical results.The accuracy of resectable types of vascular invasion was 72.52%;the accuracy of resectable vascular invasion grades was 79.39%.Conclusion:the application of multi-slice spiral CT in the diagnosis of pancreatic cancer can provide a clear understanding of the condition of vascular invasion and distant metastasis,and the accuracy of assessing resection can reach more than 70.00%,which provides a reference for clinical application.

Multi-slice spiral computed tomography in diagnosing unstable pelvic fractures in elderly and effect of less invasive stabilization

BACKGROUND Older people are more likely to experience pelvic fractures than younger people.Multi-slice spiral computed tomography(CT)uses three-dimensional(3D)reconstruction technology to generate 3D images that can clearly demonstrate the 3D space of fractures and detect fractures at a higher rate.AIM To investigate the clinical value of multi-slice spiral CT 3D reconstruction in the diagnosis of unstable pelvic fractures in the elderly as well as the effect of less invasive stabilization.METHODS A total of 86 patients with unstable pelvic fractures treated between March 2016 and March 2019 underwent femoral supracondylar bone traction before surgery.Pelvic radiography and multi-row spiral CT were performed successively once the patient’s vital signs and hemodynamic indices were stable.Secondary processing of the original data was performed to obtain 3D reconstruction images and determine the vertical displacement of the pelvis.After basic or complete reduction,minimally invasive internal fixation using hollow lag screws was performed.The detection rates of fracture location and classification by X-ray and CT reconstruction were compared.Patients were divided into two groups according to the presence or absence of preoperative 3D reconstruction to compare postoperative reduction,wound healing time,fracture healing time,hospitalization time,visual analog scale(VAS)score,poor internal fixation,and functional recovery.RESULTS The diagnostic coincidence rates of X-rays for pubic symphysis,ilium wing,sacroiliac periarticular,and sacral fractures were lower than those of CT reconstruction.The coincidence rate of CT reconstruction in the clinical classification of pelvic fractures was 100%,whereas 11 cases were misdiagnosed by X-ray;the total coincidence rate was 87.21%.The total excellent and good rates of postoperative reduction were significantly higher in the study group than in the control group(P<0.05).The wound healing,fracture healing,and hospitalization times were significantly shorter in the study group than in the control group(P<0.05).The VAS scores decreased in both groups postoperatively and were lower in the study group than in the control group(P<0.05).The total incidence of poor postoperative internal fixation was significantly lower in the study group than in the control group(P<0.05).The overall rate of postoperative functional recovery was significantly higher in the study group than in the control group(P<0.05).CONCLUSION Multi-slice spiral CT has high guiding significance for the diagnosis,classification,and treatment of unstable pelvic fractures in the elderly.Preoperative 3D reconstruction can effectively shorten the operation time and promote fracture healing,while minimally invasive internal fixation can effectively reduce pain and promote functional recovery of fracture sites,making it worthy of clinical application.

Investigation on the optical scan condition for imaging of multi-slice spiral CT liver perfusion in rats

Background Multi-slice CT liver perfusion has been widely used in experimental studies of hemodynamic changes in liver lesions, and is usually performed as an adjunct to a conventional CT examination because of its high temporal and spatial resolution, simple protocol, good reproducibility, and ability to measure hemodynamic changes of liver tissues at the capillary level. Experimental rat models, especially those of induced liver cancer, are often used in studies of hemodynamic changes in liver cancer. Carcinogenesis in rats has a similar pathological progression and characteristics resembling those in human liver cancer; as a result, rat models are often used as ideal animal models in the study of human liver cancer. However, liver perfusion imaging in rats is difficult to perform, because rats＇ livers are so small that different concentrations, flow rates, and dose of contrast agents during the CT perfusion scanning can influence the quality of liver perfusion images in rats. The purpose of this study, therefore, was to investigate the optimal scan protocol for the imaging of hepatic perfusion using a deconvolution mathematical method in rats by comparing the results of rats in different injection conditions of the contrast agent, including concentration, rate and time. Methods Plain CT scan conditions in eighty 2-month-old male Wistar rats were 5.0 mm slice thickness, 5.0 mm interval, 1.0 pitch, 120 kV tube voltage, 60 mA tube current, 512x512 matrix, and FOV 9.6 cm. Perfusion scanning was carried out with different concentrations of diatrizoate （19%, 38%, 57%, and 76%）, different injection rates （0.3 and 0.5 ml/s）, and different injection times （1, 2-3, 4-5, and 6 seconds）. The above conditions were randomly matched and adjusted to determine the best perfusion scan protocol. Three-phase contrast-enhanced scanning was performed after CT perfusion. Histological examination of the liver tissues with hematoxylin and eosin stains was done after CT scanning. Results When the concentration of the contrast agent was 19% or 38%, no pseudo-color map was created. The viscosity increased when the concentration of the contrast agent was 76%; so it is difficult to inject the contrast agent at such a high concentration. Also no pseudo-color map was generated when the injection time was short （1, 2-3, and 4-5 seconds） or the injection rate was low （0.3 ml/s）. The best perfusion images and perfusion parameters were obtained during 50 seconds scanning. Each rat was given an injection of 57% diatrizoate at 0.5 mils via the tail vein using a high-pressure syringe for 6 seconds. The perfusion parameters included hepatic blood flow （HBF）, hepatic blood volume （HBV）, mean transit time （MTT） of the contrast agent, capillary permeability-surface area product （PS）, hepatic arterial index （HAl）, hepatic artery perfusion （HAP）, and hepatic portal perfusion （HPP）. All these parameters reflected the perfusion status of liver parenchyma in normal rats. Three phases of enhancement were modified according to the time-density curves （TDCs） of the perfusion imaging： hepatic arterial phase （7 seconds）, hepatic portal venous phase （15 seconds）, and a delayed phase （23-31 seconds）. On examination by microscopy, the liver tissues were pathologically normal. Conclusions The appropriate protocol with multi-slice spiral CT liver perfusion reflected normal liver hemodynamics in rats. This study laid a solid foundation for further investigation of the physiological characteristics of liver cancer in a rat model, and was an important supplement to and reference for conventional contrast-enhanced CT scans.

多层螺旋CT增强扫描诊断结直肠癌肺转移的相关因素分析

目的研究多层螺旋CT(MSCT)增强扫描技术在结直肠癌肺转移中的诊断价值,并对肺转移的危险因素进行分析。方法入选2019年1月至2022年2月于我院就诊的结直肠癌患者223例为研究对象,比较X线、MSCT对结直肠癌肺转移的诊断效能。根据活检结果将患者分为转移组和对照组,比较两组患者的临床资料,对影响结直肠癌肺转移的危险因素进行多元Logistic回归分析。结果在评价结直肠癌肺转移的诊断效能指标中,MSCT的准确度更高,且灵敏度、特异度以及阳性和阴性预测值均高于X线,结果具有统计学差异(P<0.05)。38例肺转移患者中11例(28.95%)病灶数目≥3个,MSCT图像中绝大多数病灶为实性结节,68.35%病灶边缘不光整,81.01%的病灶分叶,54.43%的病灶出现短毛刺,82.28%的病灶呈不均匀强化,长毛刺病灶比例较低,为26.58%。多元Logistic回归分析提示癌胚抗原表达升高、肿瘤原发于直肠以及Dukes C期为导致结直肠癌肺转移的独立危险因素。结论MSCT对结直肠癌肺转移的诊断价值较高,影像表现多样化,肿瘤原发部位为直肠、癌胚抗原表达升高及Dukes C期是结直肠癌肺转移的独立危险因素,对此类患者行MSCT增强扫描具有一定的意义。

多层螺旋CT血管造影(MSCTA)诊断颅内动脉瘤的影像学特征及诊断效能研究

分析多层螺旋CT血管造影(multislice CT angiography,MSCTA)诊断颅内动脉瘤的影像学特征及诊断效能。选取河北省衡水市第五人民医院2019年1月—2022年12月收治的80例颅内动脉瘤患者为研究对象,根据随机数表法将所有患者分为对照组与观察组,每组各40例。对照组接受数字减影血管造影技术(digital subtraction angiography,DSA)诊断,观察组接受MSCTA诊断。对比两组患者不同部位的脑动脉瘤检出率、两种检测方法下的图像质量分级情况及诊断效能。研究发现,针对颅内动脉瘤的临床诊断,可为患者实施MSCTA检查,此检查与DSA检查相比同样具有理想的诊断价值,动脉瘤检出率与图像质量较高,但与DSA此类有创检查项目相比,MSCTA对患者的影响更小,具有便捷、实惠等优势,可应用于临床诊断中。

256层螺旋CT与MRI对膝关节隐性创伤骨折的诊断价值观察

目的 分析256层螺旋CT与磁共振成像(MRI)对膝关节隐性创伤骨折的诊断价值。方法选取2019年11月~2023年11月期间收治的膝关节骨折患者86例,回顾性分析其临床资料。所有患者均实施手术治疗,术前实施256层螺旋CT与MRI检查。分析256层螺旋CT与MRI检查对膝关节隐性创伤骨折的诊断价值。结果86例患者中,共79例患者发生膝关节隐性创伤骨折,其中以胫骨近端、腓骨近端、髌骨、股骨远端出现隐性创伤骨折为主。256层螺旋CT检查诊断中,诊断准确度为93.02%,敏感度为93.67%,特异度为85.71%,Kappa值为0.630。MRI检查诊断中,诊断准确度为94.19%,敏感度为94.94%,特异度为85.71%,Kappa值为0.675。结论256层螺旋CT检查与MRI检查诊断膝关节隐性创伤骨折的诊断价值均较高。

多层螺旋CT的MPR及VR重建技术对外伤性肋骨骨折的诊断价值

目的探讨多层螺旋CT(MSCT)多平面重建(MPR)、容积再现(VR)技术对外伤性肋骨骨折的诊断价值。方法回顾性分析2022年1—10月四川大学华西医院龙泉医院收治的90例外伤性肋骨骨折患者的MSCT图像,根据轴位薄层图像分别结合MPR、VR重建图像进行诊断,比较两种重建技术对肋骨骨折的诊断价值。结果90例患者共371处肋骨骨折,其中错位骨折254处,MPR及VR的诊断敏感度率分别为98.03%(249/254)、96.85%(246/254),误诊率分别为0.40%(1/250)、0.40%(1/247),MPR及VR对肋骨错位骨折诊断的敏感度及误诊率比较,差异无统计学意义(P>0.05)。MPR及VR对117处无错位骨折的诊断敏感度分别为88.03%(103/117)、74.36%(87/117),误诊率分别为2.83%(3/106)、5.43%(5/92);MPR及VR对总的肋骨骨折诊断敏感度分别为94.88%(352/371)、89.76(333/371),误诊率分别为1.12%(4/356)、1.77%(6/339);MPR对无错位骨折及总的肋骨骨折诊断敏感度高于VR,差异有统计学意义(P<0.05),而误诊率差异无统计学意义(P>0.05)。VR平均诊断时间(174.59±21.64)s短于MPR平均诊断时间(211.66±27.70)s,差异具有统计学意义(P<0.05)。结论VR诊断用时短,MPR对无错位骨折敏感度更高,合理利用两种重建技术能提高肋骨骨折诊断效率和准确性。

Imaging Effect and Accuracy Analysis of 64-Slice Spiral CT in the Diagnosis of Coronary Artery Stenosis

Objective:To analyze the imaging effect and accuracy of 64-slice spiral CT in the diagnosis of coronary artery stenosis.Methods:30 patients with suspected coronary heart disease admitted to our hospital from March 2022 to March 2023 were selected.All patients underwent both 64-slice spiral CT and digital subtraction angiography(DSA).DSA is considered the gold standard for diagnosis,so it was used to analyze the diagnostic performance of 64-slice spiral CT.Results:(1)The diagnostic results of digital subtraction angiography and 64-slice spiral CT was analyzed and compared with each other.The 64-slice spiral CT had an accuracy of 96.67%(29/30),a sensitivity 96.55%(28/29),and a specificity of 100.00%(1/1)in diagnosing coronary artery stenosis.(2)There was no significant difference between 64-slice spiral CT and digital subtraction angiography in the positive detection rate of anterior descending artery lesion,the positive detection rate of left main lesion,the positive detection rate of left circumflex artery lesion and the positive detection rate of right coronary artery lesion(P>0.05).(3)There was no significant difference between 64-slice spiral CT examination and DSA examination in identifying mild stenosis,moderate stenosis,and severe stenosis of coronary arteries(P>0.05).Conclusion:64-slice spiral CT examination can accurately determine the degree of occlusion of coronary arteries,which allows for the accurate diagnosis of coronary artery stenosis.

多层螺旋CT、肠腔充盈超声造影单独及联合检查对结肠癌的诊断价值

目的探讨多层螺旋CT、肠腔充盈超声造影单独及联合检查对结肠癌的诊断价值。方法选取98例结肠癌患者,术前均行多层螺旋CT、肠腔充盈超声造影检查。以病理检查结果为金标准,比较多层螺旋CT、肠腔充盈超声造影单独及联合检查对结肠癌、淋巴结转移及对结肠癌T分期的诊断符合率。结果病理检查结果显示,98例结肠癌患者中淋巴结转移35例。多层螺旋CT、肠腔充盈超声造影联合检查诊断结肠癌的符合率高于二者单独检查,差异有统计学意义(P﹤0.05);多层螺旋CT、肠腔充盈超声造影单独及联合检查诊断结肠癌淋巴结转移的符合率比较,差异无统计学意义(P﹥0.05)。病理检查结果显示,结肠癌T1~2期25例,T3期54例,T4期19例。多层螺旋CT、肠腔充盈超声造影联合检查诊断结肠癌T3、T4期的符合率均高于二者单独检查(P﹤0.05)。结论多层螺旋CT联合肠腔充盈超声造影检查对结肠癌的诊断价值较高。

多层螺旋CT与数字化X线摄影对多发肋骨骨折患者的诊断效果分析

目的:探讨多层螺旋CT三维成像(MSCT)与数字化X线摄影(DR)检查对多发肋骨骨折患者的诊断价值。方法:选择2022年1月-2023年11月苏州市中医医院100例疑似多发肋骨骨折患者为研究对象,均实施MSCT、DR检查,以临床诊断结果为对照,分析MSCT、DR的诊断效能。结果:100例疑似患者通过临床综合诊断,其中88例证实为多发肋骨骨折,以此结果作为对照,DR检查真阳、真阴、假阳、假阴例数分别为78、7、5、10例;MSCT检查分别为86、11、1、2例。MSCT的诊断敏感度、准确度分别为97.73%、97.00%,均高于DR的88.64%、85.00%,差异均有统计学意义(P<0.05);两种检查方式的特异度分别为58.33%、91.67%,差异无统计学意义(P>0.05)。结论:多发性肋骨骨折诊断中应用MSCT技术,诊断准确率较高,可得到清晰的影像学图像,且无创安全,方便快捷,为疾病诊治提供可靠依据。

探究多螺旋CT联合HMGB1检测在儿童先天性胸廓畸形中诊断价值

目的探究多螺旋CT联合HMGB1检测在儿童先天性胸廓畸形中诊断价值。方法选取2021年3月~2023年3月于我院就诊的57例疑似胸廓畸形患儿作为研究对象,以手术诊断为“金标准”,将确诊为胸廓畸形的43例患儿作为观察组,其余14例非胸廓畸形患儿作为对照组。分别检测观察组与对照组血清HMGB1水平。观察组患儿进行MSCT扫描检查,记录其CT相关数据。比较基础资料、不同亚型、不同急性严重程度之间CT相关数据及血清HMGB1水平;比较MSCT扫描、血清HMGB1水平检测及二者联合对先天性漏斗胸的检出率及诊断价值。结果对照组与观察组患儿性别、年龄、BMI方面比较无明显差异(P>0.05),观察组患儿血清HMGB1水平明显高于对照组(P<0.05)。不同亚型漏斗胸患儿Hailer指数、心脏旋转角、胸骨凹陷深度、CT凹陷指数、胸骨凹陷角度、血清HMGB1水平比较,无明显差别(P>0.05)。轻度漏斗胸患儿Hailer指数、心脏旋转角、胸骨凹陷深度、CT凹陷指数、血清HMGB1水平均低于中度、重度漏斗胸患儿,胸骨凹陷角度高于中度、重度漏斗胸患儿(P<0.05);中度漏斗胸患儿Hailer指数、心脏旋转角、胸骨凹陷深度、CT凹陷指数、血清HMGB1水平低于重度漏斗胸患儿,胸骨凹陷角度高于重度漏斗胸患儿(P<0.05)。MSCT联合HMGB1检测漏斗胸检出率是90.70%,远高于MSCT扫描的69.77%、血清HMGB1水平检测的41.86%(P<0.05)。ROC曲线分析MSCT扫描、血清HMGB1、二者联合检测对先天性漏斗胸灵敏度及特异度分析发现,二者联合检测的灵敏度、特异性及AUC均高于MSCT扫描及血清HMGB1。结论MSCT联合HMGB1检测能高效诊断出儿童先天性胸廓畸形,具有较高诊断价值。

多层螺旋CT检查诊断肠梗阻的应用及准确度评价

目的 研究在肠梗阻的临床诊断中应用多层螺旋CT检查的价值。方法 选取2022年1月—2023年12月新泰市人民医院收治的917例疑似肠梗阻患者为研究对象,所有受试者入院后均接受多层螺旋CT扫描。以临床表现、体格检查和影像学检查等综合诊断为金标准,分析多层螺旋CT的诊断符合率与诊断效能。结果 在疑似肠梗阻患者中,综合诊断确诊915例肠梗阻患者,多层螺旋CT诊断的准确度、灵敏度、特异度依次为99.89%(916/917)、100.00%(915/915)、50.00%(1/2),kappa值为0.666。CT对不同类型肠梗阻的诊断符合率为99.89%(914/915)。结论 多层螺旋CT检查对诊断肠梗阻具有较高的准确度、灵敏度。

64排螺旋CT冠状动脉成像诊断老年冠状动脉狭窄的应用价值

目的:探讨64排螺旋CT冠状动脉(以下简称冠脉)成像诊断老年冠状动脉狭窄的应用价值。方法:选择2020年1月—2023年6月收治的老年冠心病患者50例,均接受64排128层螺旋CT(64-SCTA)及冠状动脉造影(CAG)检查,以CAG检查结果作为冠脉狭窄诊断的“金标准”,计算64-SCTA检查的诊断价值指标,包括灵敏度、特异度和准确度。结果:64-SCTA诊断冠状动脉狭窄的灵敏度、特异度及准确度分别为64.82%,94.35%和70.80%;进一步去除钙化节段,64-SCTA诊断冠状动脉狭窄的灵敏度、特异度及准确度分别为84.09%,97.33%和84.09%,其中诊断灵敏度和准确度较前显著提高,差异有统计学意义(P<0.05),特异度较前提高,但是差异无统计学意义(P>0.05)。结论:64排螺旋CT冠状动脉成像检查诊断老年冠状动脉狭窄的灵敏度和准确度较高。

踝关节骨折的低剂量螺旋CT影像检查效果

目的 探讨踝关节骨折的低剂量螺旋CT影像检查效果。方法 研究中60例踝关节骨折患者均在2020年1月—2023年7月随机抽选自我院;临床对所有踝关节骨折患者合理展开常规剂量螺旋CT扫描操作以及低剂量螺旋CT扫描操作,对两种方法的辐射剂量、诊断符合率、客观性图像质量指标以及图像清晰度分级展开比较。结果 与常规剂量CT诊断剂量长度乘积(DLP)以及CT容积剂量指数(CTDIvol)展开比较,低剂量CT测定结果均更低(均P <0.05);低剂量CT与常规剂量CT对于总诊断符合率、CT值、噪声值(SD)、图像信噪比(SNR)以及图像清晰度展开比较,结果均未呈现出统计学差异(P> 0.05)。结论 临床对踝关节骨折患者在实施CT诊断期间,发现低剂量CT以及常规剂量CT的诊断效果均较为明显,对于踝关节的损伤位置均可以明确诊断,但低剂量螺旋CT扫描运用,可将辐射剂量显著降低,所以安全性更高。