In order to overcome the shortcomings that the reconstructed spectral reflectance may be negative when using the classic principal component analysis (PCA)to reduce the dimensions of the multi-spectral data, a nonne...In order to overcome the shortcomings that the reconstructed spectral reflectance may be negative when using the classic principal component analysis (PCA)to reduce the dimensions of the multi-spectral data, a nonnegative constrained principal component analysis method is proposed to construct a low-dimensional multi-spectral space and accomplish the conversion between the new constructed space and the multispectral space. First, the reason behind the negative data is analyzed and a nonnegative constraint is imposed on the classic PCA. Then a set of nonnegative linear independence weight vectors of principal components is obtained, by which a lowdimensional space is constructed. Finally, a nonlinear optimization technique is used to determine the projection vectors of the high-dimensional multi-spectral data in the constructed space. Experimental results show that the proposed method can keep the reconstructed spectral data in [ 0, 1 ]. The precision of the space created by the proposed method is equivalent to or even higher than that by the PCA.展开更多
This paper develops a wide-band multi-spectral space for color representationwith Aitken PCA algorithm. This novel mathematical space using the broad-band spectra matchingmethod aims at improving the accuracy of color...This paper develops a wide-band multi-spectral space for color representationwith Aitken PCA algorithm. This novel mathematical space using the broad-band spectra matchingmethod aims at improving the accuracy of color representation as well as reducing costs forprocessing and storing multi-spectral images. The results show that the space can present ourexperimental original spectral spaces (i. e. Munsell color matt and DIN-6164 color chips) with highefficiency, and that the spanning space with three eigenvectors can present the original space atmore than 98% CSCR, and when 5 eigenvectors are used it can cover almost the whole o-riginal spaces.展开更多
Based on diverse landforms, the correlation between soil organic matter content and multi-spectral band of remote sensing image was analyzed in this pa- per. In addition, the inversion models were built for the soil o...Based on diverse landforms, the correlation between soil organic matter content and multi-spectral band of remote sensing image was analyzed in this pa- per. In addition, the inversion models were built for the soil organic matter content in different landforms. The results showed that the spectral reflectance was nega- tively related to soil organic matter content; linear regression analysis of remove was performed throughout the bands using SPSS. When the inversion models were built based on all the bands, better fitting effect was obtained. The precision of in- version models built based on different landforms was higher than those built re- gardless landforms. Compared with the actual value, the identification level of soil organic matter content was 91 65% under the allowable error was 7%. It indicated that the extraction of soil organic matter with inversion model that was built based on different landforrrs was feasible with higher precision.展开更多
[Objective] The aim of this study was to extract effective feature bands of damaged rice leaves by planthoppers to make identification and classification rapidly from great amounts of imaging spectral data. [Method] T...[Objective] The aim of this study was to extract effective feature bands of damaged rice leaves by planthoppers to make identification and classification rapidly from great amounts of imaging spectral data. [Method] The experiment, using multi-spectral imaging system, acquired the multi-spectral images of damaged rice leaves from band 400 to 720 nm by interval of 5 nm. [Result] According to the principle of band index, it was calculated that the bands at 515, 510, 710, 555, 630, 535, 505, 530 and 595 nm were having high band index value with rich information and little correlation. Furthermore, the experiment used two classification methods and calcu-lated the classification accuracy higher than 90.00% for feature bands and ful bands of damaged rice leaves by planthoppers respectively. [Conclusion] It can be con-cluded that these bands can be considered as effective feature bands to identify damaged rice leaves by planthoppers quickly from a large scale of crops.展开更多
目的:对比三维多回波恢复梯度回波(3D MERGE)、三维可变反转角快速自旋回波(3D SPACE STIR)序列在腰椎间盘突出症(LDH)检查中的应用效果。方法:选择2020年1月~2022年11月收治的135例LDH患者,回顾性分析患者临床和磁共振成像(MRI)资料,...目的:对比三维多回波恢复梯度回波(3D MERGE)、三维可变反转角快速自旋回波(3D SPACE STIR)序列在腰椎间盘突出症(LDH)检查中的应用效果。方法:选择2020年1月~2022年11月收治的135例LDH患者,回顾性分析患者临床和磁共振成像(MRI)资料,所有患者均接受常规MRI扫描及3D MERGE、3D SPACE STIR序列扫描,对比3D MERGE、3D SPACE STIR序列测量神经根直径的一致性,评价两种序列的图像质量参数[信噪比(SNR)、对比噪声比(CNR)]、图像清晰度评分。结果:3D MERGE和3D SPACE STIR序列测量的L3~S1神经根直径比较差异无统计学意义(P>0.05),且两组序列测量的L3、L4、L5和S1直径均显示出较高相关性(r=0.957,0.986,0.975,0.972,P<0.05);3D MERGE序列的SNR及CNR均高于3D SPACE STIR序列,神经根显示分级、图像清晰度评分优于3D SPACE STIR序列,差异有统计学意义(P<0.05)。结论:3D MERGE、3D SPACE STIR序列在LDH神经根直径测量中具有极高一致性,3D MERGE序列较3D SPACE STIR序列能够更清晰显示神经跟的解剖形态,图像质量更好。展开更多
螺旋藻(Spirulina)藻蓝蛋白具有独特的理化特性及生理功能,是药物、食品和化妆品的天然原料,具有较大的开发潜力。为探讨螺旋藻藻蓝蛋白的研究现状与发展前景,对中国知网和Web of Science数据库中1990—2023年发表的文献进行检索并筛选...螺旋藻(Spirulina)藻蓝蛋白具有独特的理化特性及生理功能,是药物、食品和化妆品的天然原料,具有较大的开发潜力。为探讨螺旋藻藻蓝蛋白的研究现状与发展前景,对中国知网和Web of Science数据库中1990—2023年发表的文献进行检索并筛选,使用Cite Space软件对文章发文量、研究团队及研究热点进行图谱分析。综合分析可知,国内年发文量偏少,呈平稳趋势;国外年发文量持续上升,尤其近几年发文量迅速增长,且发文量超过了100篇;国外研究热点集中于藻蓝蛋白在食品、医药行业的应用方面,而国内研究热点集中在提取纯化、稳定性、功能活性的研究与应用,下一步应结合研究现状开发适合规模化生产的提取纯化工艺,进一步加强藻蓝蛋白研究的广度与深度;国内外研究群体主要是高校的相关生物技术学院或研究机构等,总体来讲,学者间存在较为密切的合作,但研究机构间尚未形成紧密的合作关系,在地域上比较分散,各大高校和研究机构应突破地区或机构间的各种限制,促进该研究领域的深度融合和快速发展,深入挖掘藻蓝蛋白在各个领域的潜在应用。展开更多
Histogram of collinear gradient-enhanced coding (HCGEC), a robust key point descriptor for multi-spectral image matching, is proposed. The HCGEC mainly encodes rough structures within an image and suppresses detaile...Histogram of collinear gradient-enhanced coding (HCGEC), a robust key point descriptor for multi-spectral image matching, is proposed. The HCGEC mainly encodes rough structures within an image and suppresses detailed textural information, which is desirable in multi-spectral image matching. Experiments on two multi-spectral data sets demonstrate that the proposed descriptor can yield significantly better results than some state-of- the-art descriptors.展开更多
Image fusion is performed between one band of multi-spectral image and two bands of hyperspectral image to produce fused image with the same spatial resolution as source multi-spectral image and the same spectral reso...Image fusion is performed between one band of multi-spectral image and two bands of hyperspectral image to produce fused image with the same spatial resolution as source multi-spectral image and the same spectral resolution as source hyperspeetral image. According to the characteristics and 3-Dimensional (3-D) feature analysis of multi-spectral and hyperspectral image data volume, the new fusion approach using 3-D wavelet based method is proposed. This approach is composed of four major procedures: Spatial and spectral resampling, 3-D wavelet transform, wavelet coefficient integration and 3-D inverse wavelet transform. Especially, a novel method, Ratio Image Based Spectral Resampling (RIBSR)method, is proposed to accomplish data resampling in spectral domain by utilizing the property of ratio image. And a new fusion rule, Average and Substitution (A&S) rule, is employed as the fusion rule to accomplish wavelet coefficient integration. Experimental results illustrate that the fusion approach using 3-D wavelet transform can utilize both spatial and spectral characteristics of source images more adequately and produce fused image with higher quality and fewer artifacts than fusion approach using 2-D wavelet transform. It is also revealed that RIBSR method is capable of interpolating the missing data more effectively and correctly, and A&S rule can integrate coefficients of source images in 3-D wavelet domain to preserve both spatial and spectral features of source images more properly.展开更多
To monitor growth and predict the yield of rice over a large area, the chlorophyll contents in the rice canopy were estimated using the unmanned aerial vehicle(UAV) remote sensing technology. In this work, multi-spect...To monitor growth and predict the yield of rice over a large area, the chlorophyll contents in the rice canopy were estimated using the unmanned aerial vehicle(UAV) remote sensing technology. In this work, multi-spectral image information of the rice crop was obtained using a 6-channel multi-spectral camera mounted on a fixed wing UAV, which was flown 600 m above the ground, between 11: 00-14: 00 on a sunny day in summer. The measured chlorophyll values were collected as sample sets. The s-REP index was screened out to estimate chlorophyll contents through the analysis of six kinds of spectral indexes of chlorophyll estimated capacity. An inversion model of the chlorophyll contents was then built using the least square support vector regression(LS-SVR)algorithm, with calibration and prediction R-square values of 0.89 and 0.83, respectively. Finally, remote sensing mapping for a UAV image of the Fangzheng County Dexter Rice Planting Park was accomplished using the inversion model. The inversion and measured values were then compared using regression fitting. R-square and root-mean-square error of the fitting model were 0.79 and 2.39,respectively. The results demonstrated that accurate estimation of rice-canopy chlorophyll contents was feasible using the LS-SVR inversion model developed using the s-REP vegetation index.展开更多
目的梳理国内多发伤急救相关研究文献,分析研究现状、热点和趋势,为我国多发伤急救研究提供借鉴和指导。方法检索中国知网数据库中2011—2021年关于多发伤急救的相关文献,使用Cite Space 6.1.R3可视化软件对该领域的年发文量、机构、作...目的梳理国内多发伤急救相关研究文献,分析研究现状、热点和趋势,为我国多发伤急救研究提供借鉴和指导。方法检索中国知网数据库中2011—2021年关于多发伤急救的相关文献,使用Cite Space 6.1.R3可视化软件对该领域的年发文量、机构、作者、关键词进行分析。结果最终纳入多发伤急救研究文献2519篇,整体发文数量较平稳,以2016年为小高峰;发文量最高的机构是华中科技大学附属同济医院。多发伤急救研究热点包括院前急救、并发症护理、风险因素分析和预后效果评估,研究前沿包括不同多发伤人群的诊断、治疗、手术和护理体会等方面。结论本文通过可视化分析国内多发伤急救研究的热点及趋势,指明了多发伤目前研究存在的问题和未来研究发展的方向,为进一步完善多发伤急救卫生服务和管理体系提供指导。展开更多
Evaluation of the impact of herbicides on maize was done through multi- spectral and multi-modal imaging and multi-spectral fluorescence imaging combined with statistical methods. Spectra containing 13 wavelengths ran...Evaluation of the impact of herbicides on maize was done through multi- spectral and multi-modal imaging and multi-spectral fluorescence imaging combined with statistical methods. Spectra containing 13 wavelengths ranging from 375 nm to 940 nm were derived from multi-spectral images in transmission, reflection and scattering mode and fluorescence images obtained using high-pass filters (F450 nm, F500 nm, F550 nm, F600 nm, F650 nm) on control maize samples and maize samples treated with Herbextra herbicide were used. The appearance of the spectra allowed us to characterize the effect of the herbicide on the maize pigment concentration. The fluorescence images allowed us to track the fate of absorbed energy and through PLS-DA and SVM-DA to discriminate the two leaf categories with very low error rates for the test, i.e. 4.9% and 2% respectively. The results of this technique can be used in the context of precision agriculture.展开更多
为了解国内外近10年护理不良事件的研究热点与前沿,为医院管理和临床护士提供参考,保障患者安全,通过检索中国期刊全文数据库(CNKI)和Web of Science(WOS)数据库,检索时限为2012年1月—2022年8月,导入CiteSpace进行可视化分析。研究显示...为了解国内外近10年护理不良事件的研究热点与前沿,为医院管理和临床护士提供参考,保障患者安全,通过检索中国期刊全文数据库(CNKI)和Web of Science(WOS)数据库,检索时限为2012年1月—2022年8月,导入CiteSpace进行可视化分析。研究显示,从发文量看,国内外学者对护理不良事件的关注度整体较高,可视化分析结果并未发现作者之间、机构之间的联系。未来减少护理不良事件的方法一定会越来越紧贴科学技术,越来越多的新型信息化平台、App等会用于医疗行业,降低护理不良事件预防的难度,但护理人员仍要重视护理安全。展开更多
Considering the problem of traditional cervical cancer detection method that brings high false negative rate (FNR) and high false positive rate (FPR), a new abnormal cervical cells detection method of multi-spectr...Considering the problem of traditional cervical cancer detection method that brings high false negative rate (FNR) and high false positive rate (FPR), a new abnormal cervical cells detection method of multi-spectral Pap smear is proposed in this thesis, on the basis of multi-spectral microscopic imaging technology and computer automotive recognition technology. At first, image in a specific wave band is segmented according to the relationship between intensity and spectrum of each pixel. Then, multi-spectral features of each pixel are extracted making use of improved cosine correlation analysis (CCA) algorithm. Combined with the characteristic of each cell's area, final definition is made. Experiments have proved the new approach could identify abnormal cells efficiently as well as lower FNR and FPR.展开更多
基金The Pre-Research Foundation of National Ministries andCommissions (No9140A16050109DZ01)the Scientific Research Program of the Education Department of Shanxi Province (No09JK701)
文摘In order to overcome the shortcomings that the reconstructed spectral reflectance may be negative when using the classic principal component analysis (PCA)to reduce the dimensions of the multi-spectral data, a nonnegative constrained principal component analysis method is proposed to construct a low-dimensional multi-spectral space and accomplish the conversion between the new constructed space and the multispectral space. First, the reason behind the negative data is analyzed and a nonnegative constraint is imposed on the classic PCA. Then a set of nonnegative linear independence weight vectors of principal components is obtained, by which a lowdimensional space is constructed. Finally, a nonlinear optimization technique is used to determine the projection vectors of the high-dimensional multi-spectral data in the constructed space. Experimental results show that the proposed method can keep the reconstructed spectral data in [ 0, 1 ]. The precision of the space created by the proposed method is equivalent to or even higher than that by the PCA.
基金rojectsupportedbytheNationalNaturalScienceFoundationofChina (No .60 1 770 0 5) .
文摘This paper develops a wide-band multi-spectral space for color representationwith Aitken PCA algorithm. This novel mathematical space using the broad-band spectra matchingmethod aims at improving the accuracy of color representation as well as reducing costs forprocessing and storing multi-spectral images. The results show that the space can present ourexperimental original spectral spaces (i. e. Munsell color matt and DIN-6164 color chips) with highefficiency, and that the spanning space with three eigenvectors can present the original space atmore than 98% CSCR, and when 5 eigenvectors are used it can cover almost the whole o-riginal spaces.
文摘Based on diverse landforms, the correlation between soil organic matter content and multi-spectral band of remote sensing image was analyzed in this pa- per. In addition, the inversion models were built for the soil organic matter content in different landforms. The results showed that the spectral reflectance was nega- tively related to soil organic matter content; linear regression analysis of remove was performed throughout the bands using SPSS. When the inversion models were built based on all the bands, better fitting effect was obtained. The precision of in- version models built based on different landforms was higher than those built re- gardless landforms. Compared with the actual value, the identification level of soil organic matter content was 91 65% under the allowable error was 7%. It indicated that the extraction of soil organic matter with inversion model that was built based on different landforrrs was feasible with higher precision.
基金Supported by National Natural Science Foundation of China under Grant(No.60968001,61168003)Natural Science Foundation of Yunnan Province under Grant(No.2011FZ079,2009CD047)National Training Programs of Innovation and Entrepreneurship for Undergraduates under Grant(No.201210681005,201310681004)~~
文摘[Objective] The aim of this study was to extract effective feature bands of damaged rice leaves by planthoppers to make identification and classification rapidly from great amounts of imaging spectral data. [Method] The experiment, using multi-spectral imaging system, acquired the multi-spectral images of damaged rice leaves from band 400 to 720 nm by interval of 5 nm. [Result] According to the principle of band index, it was calculated that the bands at 515, 510, 710, 555, 630, 535, 505, 530 and 595 nm were having high band index value with rich information and little correlation. Furthermore, the experiment used two classification methods and calcu-lated the classification accuracy higher than 90.00% for feature bands and ful bands of damaged rice leaves by planthoppers respectively. [Conclusion] It can be con-cluded that these bands can be considered as effective feature bands to identify damaged rice leaves by planthoppers quickly from a large scale of crops.
文摘目的:对比三维多回波恢复梯度回波(3D MERGE)、三维可变反转角快速自旋回波(3D SPACE STIR)序列在腰椎间盘突出症(LDH)检查中的应用效果。方法:选择2020年1月~2022年11月收治的135例LDH患者,回顾性分析患者临床和磁共振成像(MRI)资料,所有患者均接受常规MRI扫描及3D MERGE、3D SPACE STIR序列扫描,对比3D MERGE、3D SPACE STIR序列测量神经根直径的一致性,评价两种序列的图像质量参数[信噪比(SNR)、对比噪声比(CNR)]、图像清晰度评分。结果:3D MERGE和3D SPACE STIR序列测量的L3~S1神经根直径比较差异无统计学意义(P>0.05),且两组序列测量的L3、L4、L5和S1直径均显示出较高相关性(r=0.957,0.986,0.975,0.972,P<0.05);3D MERGE序列的SNR及CNR均高于3D SPACE STIR序列,神经根显示分级、图像清晰度评分优于3D SPACE STIR序列,差异有统计学意义(P<0.05)。结论:3D MERGE、3D SPACE STIR序列在LDH神经根直径测量中具有极高一致性,3D MERGE序列较3D SPACE STIR序列能够更清晰显示神经跟的解剖形态,图像质量更好。
文摘螺旋藻(Spirulina)藻蓝蛋白具有独特的理化特性及生理功能,是药物、食品和化妆品的天然原料,具有较大的开发潜力。为探讨螺旋藻藻蓝蛋白的研究现状与发展前景,对中国知网和Web of Science数据库中1990—2023年发表的文献进行检索并筛选,使用Cite Space软件对文章发文量、研究团队及研究热点进行图谱分析。综合分析可知,国内年发文量偏少,呈平稳趋势;国外年发文量持续上升,尤其近几年发文量迅速增长,且发文量超过了100篇;国外研究热点集中于藻蓝蛋白在食品、医药行业的应用方面,而国内研究热点集中在提取纯化、稳定性、功能活性的研究与应用,下一步应结合研究现状开发适合规模化生产的提取纯化工艺,进一步加强藻蓝蛋白研究的广度与深度;国内外研究群体主要是高校的相关生物技术学院或研究机构等,总体来讲,学者间存在较为密切的合作,但研究机构间尚未形成紧密的合作关系,在地域上比较分散,各大高校和研究机构应突破地区或机构间的各种限制,促进该研究领域的深度融合和快速发展,深入挖掘藻蓝蛋白在各个领域的潜在应用。
文摘Histogram of collinear gradient-enhanced coding (HCGEC), a robust key point descriptor for multi-spectral image matching, is proposed. The HCGEC mainly encodes rough structures within an image and suppresses detailed textural information, which is desirable in multi-spectral image matching. Experiments on two multi-spectral data sets demonstrate that the proposed descriptor can yield significantly better results than some state-of- the-art descriptors.
文摘Image fusion is performed between one band of multi-spectral image and two bands of hyperspectral image to produce fused image with the same spatial resolution as source multi-spectral image and the same spectral resolution as source hyperspeetral image. According to the characteristics and 3-Dimensional (3-D) feature analysis of multi-spectral and hyperspectral image data volume, the new fusion approach using 3-D wavelet based method is proposed. This approach is composed of four major procedures: Spatial and spectral resampling, 3-D wavelet transform, wavelet coefficient integration and 3-D inverse wavelet transform. Especially, a novel method, Ratio Image Based Spectral Resampling (RIBSR)method, is proposed to accomplish data resampling in spectral domain by utilizing the property of ratio image. And a new fusion rule, Average and Substitution (A&S) rule, is employed as the fusion rule to accomplish wavelet coefficient integration. Experimental results illustrate that the fusion approach using 3-D wavelet transform can utilize both spatial and spectral characteristics of source images more adequately and produce fused image with higher quality and fewer artifacts than fusion approach using 2-D wavelet transform. It is also revealed that RIBSR method is capable of interpolating the missing data more effectively and correctly, and A&S rule can integrate coefficients of source images in 3-D wavelet domain to preserve both spatial and spectral features of source images more properly.
基金Supported by the National Key R&D Program of China(2016YFD0300610)
文摘To monitor growth and predict the yield of rice over a large area, the chlorophyll contents in the rice canopy were estimated using the unmanned aerial vehicle(UAV) remote sensing technology. In this work, multi-spectral image information of the rice crop was obtained using a 6-channel multi-spectral camera mounted on a fixed wing UAV, which was flown 600 m above the ground, between 11: 00-14: 00 on a sunny day in summer. The measured chlorophyll values were collected as sample sets. The s-REP index was screened out to estimate chlorophyll contents through the analysis of six kinds of spectral indexes of chlorophyll estimated capacity. An inversion model of the chlorophyll contents was then built using the least square support vector regression(LS-SVR)algorithm, with calibration and prediction R-square values of 0.89 and 0.83, respectively. Finally, remote sensing mapping for a UAV image of the Fangzheng County Dexter Rice Planting Park was accomplished using the inversion model. The inversion and measured values were then compared using regression fitting. R-square and root-mean-square error of the fitting model were 0.79 and 2.39,respectively. The results demonstrated that accurate estimation of rice-canopy chlorophyll contents was feasible using the LS-SVR inversion model developed using the s-REP vegetation index.
文摘目的梳理国内多发伤急救相关研究文献,分析研究现状、热点和趋势,为我国多发伤急救研究提供借鉴和指导。方法检索中国知网数据库中2011—2021年关于多发伤急救的相关文献,使用Cite Space 6.1.R3可视化软件对该领域的年发文量、机构、作者、关键词进行分析。结果最终纳入多发伤急救研究文献2519篇,整体发文数量较平稳,以2016年为小高峰;发文量最高的机构是华中科技大学附属同济医院。多发伤急救研究热点包括院前急救、并发症护理、风险因素分析和预后效果评估,研究前沿包括不同多发伤人群的诊断、治疗、手术和护理体会等方面。结论本文通过可视化分析国内多发伤急救研究的热点及趋势,指明了多发伤目前研究存在的问题和未来研究发展的方向,为进一步完善多发伤急救卫生服务和管理体系提供指导。
文摘Evaluation of the impact of herbicides on maize was done through multi- spectral and multi-modal imaging and multi-spectral fluorescence imaging combined with statistical methods. Spectra containing 13 wavelengths ranging from 375 nm to 940 nm were derived from multi-spectral images in transmission, reflection and scattering mode and fluorescence images obtained using high-pass filters (F450 nm, F500 nm, F550 nm, F600 nm, F650 nm) on control maize samples and maize samples treated with Herbextra herbicide were used. The appearance of the spectra allowed us to characterize the effect of the herbicide on the maize pigment concentration. The fluorescence images allowed us to track the fate of absorbed energy and through PLS-DA and SVM-DA to discriminate the two leaf categories with very low error rates for the test, i.e. 4.9% and 2% respectively. The results of this technique can be used in the context of precision agriculture.
文摘为了解国内外近10年护理不良事件的研究热点与前沿,为医院管理和临床护士提供参考,保障患者安全,通过检索中国期刊全文数据库(CNKI)和Web of Science(WOS)数据库,检索时限为2012年1月—2022年8月,导入CiteSpace进行可视化分析。研究显示,从发文量看,国内外学者对护理不良事件的关注度整体较高,可视化分析结果并未发现作者之间、机构之间的联系。未来减少护理不良事件的方法一定会越来越紧贴科学技术,越来越多的新型信息化平台、App等会用于医疗行业,降低护理不良事件预防的难度,但护理人员仍要重视护理安全。
基金Supported by Key Project of the Tenth Five-Year Plan of the Ministry of Science and Technology of China (2001BA210A02)
文摘Considering the problem of traditional cervical cancer detection method that brings high false negative rate (FNR) and high false positive rate (FPR), a new abnormal cervical cells detection method of multi-spectral Pap smear is proposed in this thesis, on the basis of multi-spectral microscopic imaging technology and computer automotive recognition technology. At first, image in a specific wave band is segmented according to the relationship between intensity and spectrum of each pixel. Then, multi-spectral features of each pixel are extracted making use of improved cosine correlation analysis (CCA) algorithm. Combined with the characteristic of each cell's area, final definition is made. Experiments have proved the new approach could identify abnormal cells efficiently as well as lower FNR and FPR.