A new series of 1-substituted phenyl-2-（1H-1,2,4-triazol-l-yl）ethanone derivatives 3a--3f was synthe- sized and their structures were characterized by IR, 1H NMR, lSC NMR and HRMS spectral analysis. Antimicrobial ac...A new series of 1-substituted phenyl-2-（1H-1,2,4-triazol-l-yl）ethanone derivatives 3a--3f was synthe- sized and their structures were characterized by IR, 1H NMR, lSC NMR and HRMS spectral analysis. Antimicrobial activities of the derivatives were measured against both bacteria and fimgi. In vitro antifungal evaluation showed that five compotmds（3b---3f） had growth inhibitory effects on the tested fungus, and three of them（3b, 3c and 3e） showed special efficacy against Gram negative bacteria.展开更多
文摘A new series of 1-substituted phenyl-2-（1H-1,2,4-triazol-l-yl）ethanone derivatives 3a--3f was synthe- sized and their structures were characterized by IR, 1H NMR, lSC NMR and HRMS spectral analysis. Antimicrobial activities of the derivatives were measured against both bacteria and fimgi. In vitro antifungal evaluation showed that five compotmds（3b---3f） had growth inhibitory effects on the tested fungus, and three of them（3b, 3c and 3e） showed special efficacy against Gram negative bacteria.
