1,2,4-Triazine compounds were synthesized via two coupled domino strategies employing simple and readily available arylacetaldehydes/arylethyl alcohols as starting materials. The reactions proceed smoothly in one pot ...1,2,4-Triazine compounds were synthesized via two coupled domino strategies employing simple and readily available arylacetaldehydes/arylethyl alcohols as starting materials. The reactions proceed smoothly in one pot with the advantages of high functional groups tolerance, being transition metal-free, and employing environmentally friendly oxidants such as I2 and IBX. nroviding, access to the desired 1,2,4-triazine products in excellent yields.展开更多
基金Acknowledgement We are sincerely grateful for sponsorship of this project by the National Natural Science Foundation of China （No. 21372102）.
文摘1,2,4-Triazine compounds were synthesized via two coupled domino strategies employing simple and readily available arylacetaldehydes/arylethyl alcohols as starting materials. The reactions proceed smoothly in one pot with the advantages of high functional groups tolerance, being transition metal-free, and employing environmentally friendly oxidants such as I2 and IBX. nroviding, access to the desired 1,2,4-triazine products in excellent yields.
