N-Hydroxylacridinedione derivatives were synthesized by three-component reaction of aromatic aldehydes, 1,3-dicarbonyl compounds and hydroxylamine hydrochloride using triethylbenzylammonium chloride （TEBA） as the ca...N-Hydroxylacridinedione derivatives were synthesized by three-component reaction of aromatic aldehydes, 1,3-dicarbonyl compounds and hydroxylamine hydrochloride using triethylbenzylammonium chloride （TEBA） as the catalysis in water. The reaction has many advantages including good yields, easy to be separated and environmental friendliness.展开更多
The title compound N-hydroxy-9-（3＇,4＇-methylenedioxyphenyl）-1,8-dioxo-1,2,3,4,5,6,7,8,9,10-decahydroacridine （C2oH19NO5, Mr=353.36） is of orthorhombic, space group Pna2t with a=14.6914（16）, b=8.8103（10）, c=1...The title compound N-hydroxy-9-（3＇,4＇-methylenedioxyphenyl）-1,8-dioxo-1,2,3,4,5,6,7,8,9,10-decahydroacridine （C2oH19NO5, Mr=353.36） is of orthorhombic, space group Pna2t with a=14.6914（16）, b=8.8103（10）, c=12.6648（14）A°, Z=4, V=1639.3（3） A°^3 Dc=1.432 g/cm^3, μ（MoKa）=0.103 mm^-1, F（000）=744, R=0.0445 and wR=0.1043 for 2172 observed reflections （I〉 2σ（I））. X-ray analysis reveals that the pyridine and cyclohexane rings adopt boat and half-chair configurations, respectively. In addition, there is an intermolecular hydrogen bond （O（1）-H…O（3）） in the title molecule.展开更多
文摘N-Hydroxylacridinedione derivatives were synthesized by three-component reaction of aromatic aldehydes, 1,3-dicarbonyl compounds and hydroxylamine hydrochloride using triethylbenzylammonium chloride （TEBA） as the catalysis in water. The reaction has many advantages including good yields, easy to be separated and environmental friendliness.
基金This work was supported by the Foundation of "Innovation Project" of Xuzhou Normal University
文摘The title compound N-hydroxy-9-（3＇,4＇-methylenedioxyphenyl）-1,8-dioxo-1,2,3,4,5,6,7,8,9,10-decahydroacridine （C2oH19NO5, Mr=353.36） is of orthorhombic, space group Pna2t with a=14.6914（16）, b=8.8103（10）, c=12.6648（14）A°, Z=4, V=1639.3（3） A°^3 Dc=1.432 g/cm^3, μ（MoKa）=0.103 mm^-1, F（000）=744, R=0.0445 and wR=0.1043 for 2172 observed reflections （I〉 2σ（I））. X-ray analysis reveals that the pyridine and cyclohexane rings adopt boat and half-chair configurations, respectively. In addition, there is an intermolecular hydrogen bond （O（1）-H…O（3）） in the title molecule.
