血液透析对尿毒症患者血NO含量的影响

目的 探讨血液透析对尿毒症患者血ＮＯ含量的影响，探讨其在ＣＲＦ 发病过程中的作用，为治疗提供新的手段和依据；方法 对伴有高血压的尿毒症病人分为透析和非透析两组，每组３０ 例，血透前后用化学比色法测定其血液中ＮＯ 含量；结果 尿毒症患者血中ＮＯ含量明显低于健康人（ Ｐ＜ ０ ．０１） ，非血透组明显低于血透组（ Ｐ＜ ０ ．０１） ；结论 尿毒症患者血ＮＯ 低于正常人，ＨＤ 可明显提高其血中ＮＯ 含量，调整病人血中ＮＯ含量，保持最佳生理状态可改善尿毒症患者的病情。

Nitric Oxide:from a mysterious labile factor to the molecule of the Nobel Prize Recent progress in nitric oxide research

NO is now known to be an important messenger molecule in biology.It regulates a variety of functions within cells and tissues including vasodilation, neurotransmission and immunological process. This review will focus on the nitric oxide synthase gene family and recent progress on molecular genetic analysis of NOS1, NOS2 and N0S3 genes.