Two novel complexes [Zn（NIT3-py）（ip）]n 1 and [Zn（im3-py）（ip）]n 2 （NIT3-py = 2-（3＇-pyridyl）-4,4,5,5,-tetramethylimidazoline-1-oxyl-3-oxide, im3-py = 2-（3＇-pyridyl）-4,4,5,5-tetramethylimidazoline-1-oxyl, ...Two novel complexes [Zn（NIT3-py）（ip）]n 1 and [Zn（im3-py）（ip）]n 2 （NIT3-py = 2-（3＇-pyridyl）-4,4,5,5,-tetramethylimidazoline-1-oxyl-3-oxide, im3-py = 2-（3＇-pyridyl）-4,4,5,5-tetramethylimidazoline-1-oxyl, ip = isophthalate） have been synthesized and structurally determined by X-ray diffraction. Crystal data for 1： C32H36N6O8Zn, Mr= 698.04, monoclinic, space group Cc with a = 23.600（3）, b = 10.2073（12）, c = 13.4027（16）A,β = 92.586（2）°, V = 3225.3（7） A^3, Dc= 1.438 g/cm^3, F（000） = 1456,μ（MoKa） = 0.822 mm^-1, Z = 4, the final R = 0.0390 and wR = 0.1032 for 6037 independent reflections with Rint = 0.0214. Crystal data for 2： C32H36N6O6Zn, Mr= 666.04, monoclinic, space group C2/c with a = 24.434（4）, b = 13.543（2）, c = 10.2379（16） A, β = 109.024（2）°, V = 3202.8（9）A3 Dc= 1.381 g/cm^3, F（000） = 1392,μ（MoKa） = 0.820 mm^-1, Z = 4, the final R = 0.0304 and wR = 0.0658 for 2833 independent reflections with Rint = 0.0307. X-ray analysis reveals that both Zn（ Ⅱ ） ions are four-coordinated by two pyridyl-N atoms from nitroxide radicals and two carboxylate oxygen atoms to form distorted tetrahedral geometries. Each isophthalate dianion binds two Zn（ Ⅱ ） ions in a monodentate mode, leading to a I-D chain structure.展开更多
A mixed complex [Zn（C5H6N2）（HL）2] （C5H6N2 = 2-aminopyridine, H2L = acetylacetone） has been synthesized and characterized by IR, elemental analysis and X-ray single-crystal diffraction analysis. The crystal belon...A mixed complex [Zn（C5H6N2）（HL）2] （C5H6N2 = 2-aminopyridine, H2L = acetylacetone） has been synthesized and characterized by IR, elemental analysis and X-ray single-crystal diffraction analysis. The crystal belongs to monoclinic, space group P21/c with a = 7.4490（15）, b = 8.2650（17）, c = 27.615（6） A°, β= 101.69（3）°, V = 1664.9（6）A°^3, Z = 4, Mr = 357.70, Dc = 1.427 g/cm^3, F（000） = 744, μ = 1.493 mm^-1, R = 0.0309 and wR = 0.0771. The Zn（Ⅱ） is coordinated by one nitrogen atom from 2-aminopyridine and four oxygen atoms from two acetylacetone anions to furnish a distorted square pyramid geometry. The complex forms a three-dimensional network through intermolecular hydrogen bonds.展开更多
A novel Zn（Ⅱ） complex, [ZnL2（H2O）4]·H2O（1, HL = 2-（nicotinoyloxy）acetic acid）, was synthesized using Zn（OAc）2·2H2O and 2-（nicotinoyloxy）acetic acid as raw materials. Its structure has been eluci...A novel Zn（Ⅱ） complex, [ZnL2（H2O）4]·H2O（1, HL = 2-（nicotinoyloxy）acetic acid）, was synthesized using Zn（OAc）2·2H2O and 2-（nicotinoyloxy）acetic acid as raw materials. Its structure has been elucidated by elemental analysis, IR and single-crystal X-ray diffraction. The structural analysis revealed that complex 1 crystallizes in triclinic, space group P1 and the Zn（Ⅱ） atom is six-coordinated with two N atoms from two different 2-（nicotinoyloxy）acetate anion ligands and four O atoms from coordinated water molecules. Complex 1 forms a 3D network structure by O–H···O hydrogen bonds. The antitumor activities of 2-（nicotinoyloxy）acetic acid ligand and its Zn（Ⅱ） complex were evaluated against human lung adenocarcinoma A549 cells, human hepatoma SMMC-7721 cells and human colon carcinoma Wi Dr cells.展开更多
A new Zn（Ⅱ） complex, [Zn（L）2（phen）（H2O）]（1, HL = N-acetyl-L-phenylalanine, phen = 1,10-phenanthroline） has been synthesized and characterized by elemental analysis, IR and X-ray single-crystal diffraction a...A new Zn（Ⅱ） complex, [Zn（L）2（phen）（H2O）]（1, HL = N-acetyl-L-phenylalanine, phen = 1,10-phenanthroline） has been synthesized and characterized by elemental analysis, IR and X-ray single-crystal diffraction analysis. The Zn（Ⅱ） complex belongs to monoclinic, space group P21 with a = 12.6749（13）, b = 5.5965（6）, c = 22.985（2） A, β = 104.296（2）°, V = 1580.0（3） A^3, Z = 2, Mr = 676.02, Dc = 1.421 μg·m^（-3）, μ = 0.833 mm^-1, F（000） = 704, and the final R = 0.0460, wR = 0.0899 for 4422 observed reflections with I 〉 2σ（I）. The molecules form a 1D chained structure by hydrogen bonds. The antitumor activities of Zn（Ⅱ） complex against human hepatoma SMMC-7721 cells, human lung adenocarcinoma A549 cells and human colon carcinoma WiDr cells have also been investigated.展开更多
The electrospray ionization mass spectrometry investigation showed that the binding sites of [ZnL]^2＋, where L is 2-[bis（2- aminoethyl）amino]ethanol, with oxidized insulin B chain are Phel, His5 and Arg22, which le...The electrospray ionization mass spectrometry investigation showed that the binding sites of [ZnL]^2＋, where L is 2-[bis（2- aminoethyl）amino]ethanol, with oxidized insulin B chain are Phel, His5 and Arg22, which lead to the selective cleavages of the peptide bonds at Phe1-Val2, His5-Leu6, Glu21-Arg22, and Arg22-Gly23 of oxidized insulin B chain.展开更多
A new Zn（II） complex, [ZnL2Br2] （L = triadimenol） was synthesized by the reaction of ZnBr2 with the commercial fungicide of triadimenol, then characterized by elemental analysis, IR spectroscopy and single-crystal...A new Zn（II） complex, [ZnL2Br2] （L = triadimenol） was synthesized by the reaction of ZnBr2 with the commercial fungicide of triadimenol, then characterized by elemental analysis, IR spectroscopy and single-crystal X-ray diffraction. The crystal structure shows that the complex [ZnL2Br2] crystallizes in orthorhombic, Pnam space group with a = 11.263（2）, b = 8.4478（15）, c = 36.125 （7） A, V = 3437.2 （11 ） ,A Z = 4, C28H36Br2C12N604Zn, Mr = 816.72, Dc = 1.578 g/cm3, F（000） = 1648,μ = 3.236 mm-1, the final R = 0.0388 and wR = 0.0879 for 2399 observed reflections with I 〉 2σ（/）. The central metals adopt square plane coordination geometry. And intermolecular hydrogen bonds connect Zn（Ⅱ） into a one-dimensional chain. In addition, the title complex and triadimenol were screened for antifungal activities against four selected fungi using the mycelial growth rate method. The results indicate that the complex synthesized shows better antifungal activities than the ligand triadimenol.展开更多
Two new three-dimensional supramolecular complexes, namely, [Cd(cba)2(bib)]n(1) and [Zn(cba)2(bib)]2 n(2)(Hcba = 2-chlorinebenzoic acid, bib = 1,4-bis(imidazol-1-yl)-butane)were hydrothermally designed and synthesized...Two new three-dimensional supramolecular complexes, namely, [Cd(cba)2(bib)]n(1) and [Zn(cba)2(bib)]2 n(2)(Hcba = 2-chlorinebenzoic acid, bib = 1,4-bis(imidazol-1-yl)-butane)were hydrothermally designed and synthesized. Their structures were determined by elemental analyses, IR spectroscopy, TG, fluorescence spectroscopy, single-crystal and powder X-ray diffraction. Complex 1 exhibits a one-dimensional zigzag chain and complex 2 shows a zero-dimensional structure, which were further extended into three-dimensional supramolecular structures through hydrogen bonds and π-π stacking interactions.展开更多
Two novel complexes [Zn（Him-thz）2（NO3）]·NO3 1 and [Ni（Him-thz）2（NO3）]·NO3 2 （Him-thz = 2-（2＇-thiazole）-4,4,5,5-teramethyl-dihydro-1H-imidazolyl-1-hydroxy） have been prepared and structurally cha...Two novel complexes [Zn（Him-thz）2（NO3）]·NO3 1 and [Ni（Him-thz）2（NO3）]·NO3 2 （Him-thz = 2-（2＇-thiazole）-4,4,5,5-teramethyl-dihydro-1H-imidazolyl-1-hydroxy） have been prepared and structurally characterized by X-ray diffraction method. Both complexes crystallize in orthorho- mbic, space group P21 21 2, Z = 2. Crystal data for 1： ZnC20H30N8O8S2, Mr = 640.2, a = 13.1630（14）, b = 10.5149（11）, c = 10.6670（11） A°, V= 1476.4（3）A°^3, Dc = 1.440 g/cm^3, μ（MoKa） = 1.028 mm^-1, F（000） = 664, R = 0.0398 and wR = 0.0901 for 2131 observed reflections with I 〉 2σ（I）. Crystal data for 2： NiC20H30N8O8S2, Mr = 633.36, a = 13.1611（7）, b = 10.4833（6）, c = 10.6928（6） .4,, V = 1475.30（14）A°^3, Dc = 1.426 g/cm^3 ,μ（MoKa） = 0.854 mm^-1, F（000） = 660, R = 0.0281 and wR = 0.0797 for 3099 observed reflections with I 〉 2σ（I）. X-ray analysis reveals that the crystal structures consist of [M（Him-thz）2（NO3）]^＋ （M = Zn, Ni） moiety and a NO3^- anion. Both Zinc（Ⅱ） and Nickel（Ⅱ） ions are six-coordinated with distorted octahedral geometries.展开更多
ABSTRAC Two new complexes [Cd（2,4＇-bpdc）（DPPZ）]2n·n H2O（1） and [Zn（2,4＇-Hbpdc）2（DPPZ）]· H2O（DPPZ = dipyrido[3,2-a：2＇,3＇-c]phenazine, 2,4＇-H2bpdc = 2,4＇-biphenyldicarboxylic acid） have been...ABSTRAC Two new complexes [Cd（2,4＇-bpdc）（DPPZ）]2n·n H2O（1） and [Zn（2,4＇-Hbpdc）2（DPPZ）]· H2O（DPPZ = dipyrido[3,2-a：2＇,3＇-c]phenazine, 2,4＇-H2bpdc = 2,4＇-biphenyldicarboxylic acid） have been hydrothermally synthesized. The structure of complex 1 was determined by single-crystal X-ray diffraction diffraction and further characterized by elemental analysis, IR spectrum, powder X-ray diffraction（XRD） and single-crystal X-ray diffraction. Complex 1 has 1D chains, which are further connected by π-π stacking interactions of neighbouring chains, generating a steady 3D supramolecular structure. Complex 2 shows the isolated mononuclear units, which are further extended to a 2D supramolecular layered structure through π-π stacking interactions and hydrogen bonds. Furthermore, complexes 1 and 2 exhibit green photoluminescent properties at room temperature.展开更多
A novel zinc（Ⅱ） complex of empirical formula,ZnL2（L=anionic forms of S-benzyl-β-N-（2,4-dichlorobenzylidene） hydrazine carbodithioate）,has been synthesized and characterized by elemental analysis,IR spectra and...A novel zinc（Ⅱ） complex of empirical formula,ZnL2（L=anionic forms of S-benzyl-β-N-（2,4-dichlorobenzylidene） hydrazine carbodithioate）,has been synthesized and characterized by elemental analysis,IR spectra and single-crystal X-ray diffraction.The crystal belongs to the triclinic system,space group P with a = 9.3168（9）,b = 13.0353（13）,c = 14.7702（15） ,α = 71.2860（10）,= 87.5140（10）,γ = 79.4480（10）o,V = 1670.0（3） 3,Z = 2,Mr = 773.93,Dc = 1.539 g/cm3,μ = 1.334 mm-1,F（000） = 784,the final R = 0.0403 and wR = 0.0800 for 4060 observed reflections with I〉2（I）.In the crystal structure,the zinc（Ⅱ） complex has a distorted tetrahedral geometry in which the zinc ion is coordinated by the nitrogen and sulfur atoms from two Schiff base ligands,respectively.The preliminary bioassay indicates that the Schiff base and its zinc complex exhibit inhibitory activity against the human gastric cancer cell lines（MKN45） and hepatoma cell lines（HepG2）.展开更多
The binuclear Zn(Ⅱ) complex [Zn2(L)2(Mf)2] with 2-hydroxyacetophenone benzoylhydrazone(H2L) and monodentate N-heterocycle,morphine(Mf) has been synthesized and characterized by elemental analysis,IR,UV,molar conducti...The binuclear Zn(Ⅱ) complex [Zn2(L)2(Mf)2] with 2-hydroxyacetophenone benzoylhydrazone(H2L) and monodentate N-heterocycle,morphine(Mf) has been synthesized and characterized by elemental analysis,IR,UV,molar conductivity,TG and X-ray diffraction structural analysis.Crystal data: monoclinic,space group P21/n with a=1.263 9(6) nm,b=1.085 2(4) nm,c=1.313 4(5) nm,β=92.16(2)°,V=1.800(1) nm3,Z=2,Dc=1.493 g.cm-3,μ= 1.388 mm-1,F(000) =840,and final R =0.038 4,wR =0.087 9.The two Zn (Ⅱ) centers in the centrosymmetric binuclear complex are bridged by phenolic oxygen atoms with Zn…Zn separation of 0.315 0(1) nm.The coordina-tion geometry of each Zn(Ⅱ) atom is trigonal bipyramidal.The fluorescence activities of ligand and the complex were also studied.展开更多
基金the National Natural Science Foundation of China (Nos. 20471032, 20331010)
文摘Two novel complexes [Zn（NIT3-py）（ip）]n 1 and [Zn（im3-py）（ip）]n 2 （NIT3-py = 2-（3＇-pyridyl）-4,4,5,5,-tetramethylimidazoline-1-oxyl-3-oxide, im3-py = 2-（3＇-pyridyl）-4,4,5,5-tetramethylimidazoline-1-oxyl, ip = isophthalate） have been synthesized and structurally determined by X-ray diffraction. Crystal data for 1： C32H36N6O8Zn, Mr= 698.04, monoclinic, space group Cc with a = 23.600（3）, b = 10.2073（12）, c = 13.4027（16）A,β = 92.586（2）°, V = 3225.3（7） A^3, Dc= 1.438 g/cm^3, F（000） = 1456,μ（MoKa） = 0.822 mm^-1, Z = 4, the final R = 0.0390 and wR = 0.1032 for 6037 independent reflections with Rint = 0.0214. Crystal data for 2： C32H36N6O6Zn, Mr= 666.04, monoclinic, space group C2/c with a = 24.434（4）, b = 13.543（2）, c = 10.2379（16） A, β = 109.024（2）°, V = 3202.8（9）A3 Dc= 1.381 g/cm^3, F（000） = 1392,μ（MoKa） = 0.820 mm^-1, Z = 4, the final R = 0.0304 and wR = 0.0658 for 2833 independent reflections with Rint = 0.0307. X-ray analysis reveals that both Zn（ Ⅱ ） ions are four-coordinated by two pyridyl-N atoms from nitroxide radicals and two carboxylate oxygen atoms to form distorted tetrahedral geometries. Each isophthalate dianion binds two Zn（ Ⅱ ） ions in a monodentate mode, leading to a I-D chain structure.
基金This work was supported by Qingdao Science and Technology Plan Items (03-3-nsh-28)
文摘A mixed complex [Zn（C5H6N2）（HL）2] （C5H6N2 = 2-aminopyridine, H2L = acetylacetone） has been synthesized and characterized by IR, elemental analysis and X-ray single-crystal diffraction analysis. The crystal belongs to monoclinic, space group P21/c with a = 7.4490（15）, b = 8.2650（17）, c = 27.615（6） A°, β= 101.69（3）°, V = 1664.9（6）A°^3, Z = 4, Mr = 357.70, Dc = 1.427 g/cm^3, F（000） = 744, μ = 1.493 mm^-1, R = 0.0309 and wR = 0.0771. The Zn（Ⅱ） is coordinated by one nitrogen atom from 2-aminopyridine and four oxygen atoms from two acetylacetone anions to furnish a distorted square pyramid geometry. The complex forms a three-dimensional network through intermolecular hydrogen bonds.
基金supported by the National Natural Science Foundation of China(No.21171132)the Project of Shandong Province Higher Educational Science and Technology Program(J14LC01)Science Foundation of Weifang
文摘A novel Zn（Ⅱ） complex, [ZnL2（H2O）4]·H2O（1, HL = 2-（nicotinoyloxy）acetic acid）, was synthesized using Zn（OAc）2·2H2O and 2-（nicotinoyloxy）acetic acid as raw materials. Its structure has been elucidated by elemental analysis, IR and single-crystal X-ray diffraction. The structural analysis revealed that complex 1 crystallizes in triclinic, space group P1 and the Zn（Ⅱ） atom is six-coordinated with two N atoms from two different 2-（nicotinoyloxy）acetate anion ligands and four O atoms from coordinated water molecules. Complex 1 forms a 3D network structure by O–H···O hydrogen bonds. The antitumor activities of 2-（nicotinoyloxy）acetic acid ligand and its Zn（Ⅱ） complex were evaluated against human lung adenocarcinoma A549 cells, human hepatoma SMMC-7721 cells and human colon carcinoma Wi Dr cells.
基金supported by the National Natural Science Foundation of China(No.21171132)the Project of Shandong Province Higher Educational Science and Technology Program(J14LC01)Science Foundation of Weifang
文摘A new Zn（Ⅱ） complex, [Zn（L）2（phen）（H2O）]（1, HL = N-acetyl-L-phenylalanine, phen = 1,10-phenanthroline） has been synthesized and characterized by elemental analysis, IR and X-ray single-crystal diffraction analysis. The Zn（Ⅱ） complex belongs to monoclinic, space group P21 with a = 12.6749（13）, b = 5.5965（6）, c = 22.985（2） A, β = 104.296（2）°, V = 1580.0（3） A^3, Z = 2, Mr = 676.02, Dc = 1.421 μg·m^（-3）, μ = 0.833 mm^-1, F（000） = 704, and the final R = 0.0460, wR = 0.0899 for 4422 observed reflections with I 〉 2σ（I）. The molecules form a 1D chained structure by hydrogen bonds. The antitumor activities of Zn（Ⅱ） complex against human hepatoma SMMC-7721 cells, human lung adenocarcinoma A549 cells and human colon carcinoma WiDr cells have also been investigated.
文摘The electrospray ionization mass spectrometry investigation showed that the binding sites of [ZnL]^2＋, where L is 2-[bis（2- aminoethyl）amino]ethanol, with oxidized insulin B chain are Phel, His5 and Arg22, which lead to the selective cleavages of the peptide bonds at Phe1-Val2, His5-Leu6, Glu21-Arg22, and Arg22-Gly23 of oxidized insulin B chain.
基金the National Natural Science Foundation(21373161)New Century Excellent Talents in University of Ministry of Education of China(NCET-12-1047)
文摘A new Zn（II） complex, [ZnL2Br2] （L = triadimenol） was synthesized by the reaction of ZnBr2 with the commercial fungicide of triadimenol, then characterized by elemental analysis, IR spectroscopy and single-crystal X-ray diffraction. The crystal structure shows that the complex [ZnL2Br2] crystallizes in orthorhombic, Pnam space group with a = 11.263（2）, b = 8.4478（15）, c = 36.125 （7） A, V = 3437.2 （11 ） ,A Z = 4, C28H36Br2C12N604Zn, Mr = 816.72, Dc = 1.578 g/cm3, F（000） = 1648,μ = 3.236 mm-1, the final R = 0.0388 and wR = 0.0879 for 2399 observed reflections with I 〉 2σ（/）. The central metals adopt square plane coordination geometry. And intermolecular hydrogen bonds connect Zn（Ⅱ） into a one-dimensional chain. In addition, the title complex and triadimenol were screened for antifungal activities against four selected fungi using the mycelial growth rate method. The results indicate that the complex synthesized shows better antifungal activities than the ligand triadimenol.
基金supported by the Science and Technology development plan of Jilin Province(2015052006JH)Science and technology research project of Education Department of Jilin Province(2016219)+1 种基金Center for Science and Technology Innovation on Target recognition and photocatalytic degradation Materials of Jilin Province(20180623042TC)Science and technology development plan of Siping city(2013055)
文摘Two new three-dimensional supramolecular complexes, namely, [Cd(cba)2(bib)]n(1) and [Zn(cba)2(bib)]2 n(2)(Hcba = 2-chlorinebenzoic acid, bib = 1,4-bis(imidazol-1-yl)-butane)were hydrothermally designed and synthesized. Their structures were determined by elemental analyses, IR spectroscopy, TG, fluorescence spectroscopy, single-crystal and powder X-ray diffraction. Complex 1 exhibits a one-dimensional zigzag chain and complex 2 shows a zero-dimensional structure, which were further extended into three-dimensional supramolecular structures through hydrogen bonds and π-π stacking interactions.
基金This work was supported by the National Natural Science Foundation of China (No. 20471026) and the Natural Science Foundation of Henan province (No. 0311021200)
文摘Two novel complexes [Zn（Him-thz）2（NO3）]·NO3 1 and [Ni（Him-thz）2（NO3）]·NO3 2 （Him-thz = 2-（2＇-thiazole）-4,4,5,5-teramethyl-dihydro-1H-imidazolyl-1-hydroxy） have been prepared and structurally characterized by X-ray diffraction method. Both complexes crystallize in orthorho- mbic, space group P21 21 2, Z = 2. Crystal data for 1： ZnC20H30N8O8S2, Mr = 640.2, a = 13.1630（14）, b = 10.5149（11）, c = 10.6670（11） A°, V= 1476.4（3）A°^3, Dc = 1.440 g/cm^3, μ（MoKa） = 1.028 mm^-1, F（000） = 664, R = 0.0398 and wR = 0.0901 for 2131 observed reflections with I 〉 2σ（I）. Crystal data for 2： NiC20H30N8O8S2, Mr = 633.36, a = 13.1611（7）, b = 10.4833（6）, c = 10.6928（6） .4,, V = 1475.30（14）A°^3, Dc = 1.426 g/cm^3 ,μ（MoKa） = 0.854 mm^-1, F（000） = 660, R = 0.0281 and wR = 0.0797 for 3099 observed reflections with I 〉 2σ（I）. X-ray analysis reveals that the crystal structures consist of [M（Him-thz）2（NO3）]^＋ （M = Zn, Ni） moiety and a NO3^- anion. Both Zinc（Ⅱ） and Nickel（Ⅱ） ions are six-coordinated with distorted octahedral geometries.
基金Supported by the Program for NNSFC(21407064,21576112)NSF of Jilin Province(20130521019JH)the Science and Technology Development Plan of Siping City(2014052,2015049)
文摘ABSTRAC Two new complexes [Cd（2,4＇-bpdc）（DPPZ）]2n·n H2O（1） and [Zn（2,4＇-Hbpdc）2（DPPZ）]· H2O（DPPZ = dipyrido[3,2-a：2＇,3＇-c]phenazine, 2,4＇-H2bpdc = 2,4＇-biphenyldicarboxylic acid） have been hydrothermally synthesized. The structure of complex 1 was determined by single-crystal X-ray diffraction diffraction and further characterized by elemental analysis, IR spectrum, powder X-ray diffraction（XRD） and single-crystal X-ray diffraction. Complex 1 has 1D chains, which are further connected by π-π stacking interactions of neighbouring chains, generating a steady 3D supramolecular structure. Complex 2 shows the isolated mononuclear units, which are further extended to a 2D supramolecular layered structure through π-π stacking interactions and hydrogen bonds. Furthermore, complexes 1 and 2 exhibit green photoluminescent properties at room temperature.
基金supported by NNSFC (No.21001071)Foundation for University Key Teacher by Henan Educational Committee (2010GGJS-157)NSF of Henan Educational Committee (2011B150028)
文摘A novel zinc（Ⅱ） complex of empirical formula,ZnL2（L=anionic forms of S-benzyl-β-N-（2,4-dichlorobenzylidene） hydrazine carbodithioate）,has been synthesized and characterized by elemental analysis,IR spectra and single-crystal X-ray diffraction.The crystal belongs to the triclinic system,space group P with a = 9.3168（9）,b = 13.0353（13）,c = 14.7702（15） ,α = 71.2860（10）,= 87.5140（10）,γ = 79.4480（10）o,V = 1670.0（3） 3,Z = 2,Mr = 773.93,Dc = 1.539 g/cm3,μ = 1.334 mm-1,F（000） = 784,the final R = 0.0403 and wR = 0.0800 for 4060 observed reflections with I〉2（I）.In the crystal structure,the zinc（Ⅱ） complex has a distorted tetrahedral geometry in which the zinc ion is coordinated by the nitrogen and sulfur atoms from two Schiff base ligands,respectively.The preliminary bioassay indicates that the Schiff base and its zinc complex exhibit inhibitory activity against the human gastric cancer cell lines（MKN45） and hepatoma cell lines（HepG2）.
文摘The binuclear Zn(Ⅱ) complex [Zn2(L)2(Mf)2] with 2-hydroxyacetophenone benzoylhydrazone(H2L) and monodentate N-heterocycle,morphine(Mf) has been synthesized and characterized by elemental analysis,IR,UV,molar conductivity,TG and X-ray diffraction structural analysis.Crystal data: monoclinic,space group P21/n with a=1.263 9(6) nm,b=1.085 2(4) nm,c=1.313 4(5) nm,β=92.16(2)°,V=1.800(1) nm3,Z=2,Dc=1.493 g.cm-3,μ= 1.388 mm-1,F(000) =840,and final R =0.038 4,wR =0.087 9.The two Zn (Ⅱ) centers in the centrosymmetric binuclear complex are bridged by phenolic oxygen atoms with Zn…Zn separation of 0.315 0(1) nm.The coordina-tion geometry of each Zn(Ⅱ) atom is trigonal bipyramidal.The fluorescence activities of ligand and the complex were also studied.
