A highly flexible green synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives with CuI nanoparticles as catalyst under solvent-free conditions

CuI nanoparticles as an efficient catalyst have been used for the preparation of 1H-pyrazolo[l,2- b]phthalazine-5,10-diones by the four-component condensation reaction of phthalic anhydride, hydrazine monohydrate, aromatic aldehydes and malononitrile or ethyl cyanoacetate under solvent- free conditions in good to excellent yields, short reaction times and environmentally benign, milder reaction conditions.

A convenient synthesis of 2-aminocyclohex-1-ene-1-carboxylic esters by FeCl_3/SiO_2 nanoparticles as robust and efficient catalyst

A simple and green method has been developed for the synthesis of 2-aminocyclohex-l-ene-l- carboxylic esters through a one-pot three-component condensation reaction of primary amines, ethyl acetoacetate and chalcones using FeCI3/SiO2 nanoparticles in ethanol. This method has several advantages such as high to excellent product yields in short time, using an inexpensive and reusable catalyst and available starting material.