This study prospectively examined the intranasal distribution of nasal spray after nasal septal correction and decongestant administration. A cohort of 20 patients was assessed for the distribution of nasal spray befo...This study prospectively examined the intranasal distribution of nasal spray after nasal septal correction and decongestant administration. A cohort of 20 patients was assessed for the distribution of nasal spray before and after nasal septum surgery. Sprays were dyed and administered one puff per nostril when patients hold their head up in an upright position. Before and after decongestant admini-stration, the intranasal distribution was semi-quantitatively determined by nasal endoscopy. The results showed that the dyed drug was preferentially sprayed onto the nasal vestibule, the head of the inferior turbinate, the anterior part of septum and nasal floor. As far as the anterior-inferior segment of the nasal cavity was concerned, the distribution was found to be influenced neither by the decongestant nor by the surgery (P〉0.05). However, both the decongestant and surgery expanded the distribution to the anatomical structures in the superior and posterior nasal cavity such as olfactory fissure, middle turbinate head and middle nasal meatus. No distribution was observed in the sphenoethmoidal recess, posterior septum, tail of inferior turbinate and nasopharynx. It was concluded that nasal septum surgery and decongestant administration significantly improves nasal spray distribution in the nasal cavity.展开更多
目的探究鼻内镜下鼻中隔矫正术加鼻窦开放治疗慢性鼻窦炎伴鼻中隔偏曲(deviation of nasal sep⁃tum,DNS)的效果。方法回顾性选取2022年1月—2024年1月宁德市中医院收治的78例慢性鼻窦炎伴DNS患者的临床资料,按治疗方案不同将患者分为对...目的探究鼻内镜下鼻中隔矫正术加鼻窦开放治疗慢性鼻窦炎伴鼻中隔偏曲(deviation of nasal sep⁃tum,DNS)的效果。方法回顾性选取2022年1月—2024年1月宁德市中医院收治的78例慢性鼻窦炎伴DNS患者的临床资料,按治疗方案不同将患者分为对照组和观察组,各39例。对照组予以鼻内镜下鼻窦开放手术,观察组予以鼻内镜下同期行鼻中隔矫正术加鼻窦开放手术。比较两组临床疗效、并发症发生率、症状评分、鼻腔鼻窦情况。结果观察组治疗总有效率为94.87%(37/39),高于对照组的79.49%(31/39),差异有统计学意义(χ^(2)=4.129,P<0.05)。观察组并发症总发生率低于对照组,差异有统计学意义(P<0.05)。术后3个月,观察组鼻塞、脓涕、嗅觉减退、呼吸困难症状评分均低于对照组,差异有统计学意义(P均<0.05)。术后3个月,观察组鼻内镜CT Lund-Mackay评分、鼻腔鼻窦结局测试-22量表评分均低于对照组,差异有统计学意义(P均<0.05)。结论鼻内镜下鼻中隔矫正术加鼻窦开放治疗慢性鼻窦炎伴DNS的疗效确切,同时也能明显减少并发症发生率,促进症状消退,加快鼻腔鼻窦功能恢复。展开更多
目的比较鼻内镜辅助下低温等离子技术与传统唇龈沟入路在鼻前庭囊肿手术中的疗效。方法收集2013年1月-2016年11月在右江民族医学院附属医院耳鼻咽喉头颈外科收住的鼻前庭囊肿患者共38例,分为对照组20例和实验组18例,对照组采用唇龈沟入...目的比较鼻内镜辅助下低温等离子技术与传统唇龈沟入路在鼻前庭囊肿手术中的疗效。方法收集2013年1月-2016年11月在右江民族医学院附属医院耳鼻咽喉头颈外科收住的鼻前庭囊肿患者共38例,分为对照组20例和实验组18例,对照组采用唇龈沟入路手术,实验组采用鼻内镜辅助下低温等离子消融,比较两组患者手术时间、术中出血量、术后住院时间、术后并发症以及复发情况等。结果实验组与对照组比较,平均手术时间减少[(65.45±27.51)vs(34.72±17.61)min,P=0.000]、术中出血量减少[(22.35±18.41)vs(3.17±1.69)ml,P=0.000]、术后住院时间缩短[(6.35±0.75)vs(3.61±1.19)d,P=0.000]和术后并发症减少(16 vs 1,P=0.000),两组复发情况差异无统计学意义(1 vs 0,P=0.783)。结论鼻内镜辅助下低温等离子技术治疗鼻前庭囊肿相对于传统唇龈沟入路,具有时间短、创伤小、恢复快、操作简单和疗效好的优势,值得推广。展开更多
基金supported by a grant from National Natural Science Foundation of China(No.81070772)Zhuhai Medical Scientific Research Fund(No.PC20081046)
文摘This study prospectively examined the intranasal distribution of nasal spray after nasal septal correction and decongestant administration. A cohort of 20 patients was assessed for the distribution of nasal spray before and after nasal septum surgery. Sprays were dyed and administered one puff per nostril when patients hold their head up in an upright position. Before and after decongestant admini-stration, the intranasal distribution was semi-quantitatively determined by nasal endoscopy. The results showed that the dyed drug was preferentially sprayed onto the nasal vestibule, the head of the inferior turbinate, the anterior part of septum and nasal floor. As far as the anterior-inferior segment of the nasal cavity was concerned, the distribution was found to be influenced neither by the decongestant nor by the surgery (P〉0.05). However, both the decongestant and surgery expanded the distribution to the anatomical structures in the superior and posterior nasal cavity such as olfactory fissure, middle turbinate head and middle nasal meatus. No distribution was observed in the sphenoethmoidal recess, posterior septum, tail of inferior turbinate and nasopharynx. It was concluded that nasal septum surgery and decongestant administration significantly improves nasal spray distribution in the nasal cavity.
文摘目的探究鼻内镜下鼻中隔矫正术加鼻窦开放治疗慢性鼻窦炎伴鼻中隔偏曲(deviation of nasal sep⁃tum,DNS)的效果。方法回顾性选取2022年1月—2024年1月宁德市中医院收治的78例慢性鼻窦炎伴DNS患者的临床资料,按治疗方案不同将患者分为对照组和观察组,各39例。对照组予以鼻内镜下鼻窦开放手术,观察组予以鼻内镜下同期行鼻中隔矫正术加鼻窦开放手术。比较两组临床疗效、并发症发生率、症状评分、鼻腔鼻窦情况。结果观察组治疗总有效率为94.87%(37/39),高于对照组的79.49%(31/39),差异有统计学意义(χ^(2)=4.129,P<0.05)。观察组并发症总发生率低于对照组,差异有统计学意义(P<0.05)。术后3个月,观察组鼻塞、脓涕、嗅觉减退、呼吸困难症状评分均低于对照组,差异有统计学意义(P均<0.05)。术后3个月,观察组鼻内镜CT Lund-Mackay评分、鼻腔鼻窦结局测试-22量表评分均低于对照组,差异有统计学意义(P均<0.05)。结论鼻内镜下鼻中隔矫正术加鼻窦开放治疗慢性鼻窦炎伴DNS的疗效确切,同时也能明显减少并发症发生率,促进症状消退,加快鼻腔鼻窦功能恢复。
文摘目的比较鼻内镜辅助下低温等离子技术与传统唇龈沟入路在鼻前庭囊肿手术中的疗效。方法收集2013年1月-2016年11月在右江民族医学院附属医院耳鼻咽喉头颈外科收住的鼻前庭囊肿患者共38例,分为对照组20例和实验组18例,对照组采用唇龈沟入路手术,实验组采用鼻内镜辅助下低温等离子消融,比较两组患者手术时间、术中出血量、术后住院时间、术后并发症以及复发情况等。结果实验组与对照组比较,平均手术时间减少[(65.45±27.51)vs(34.72±17.61)min,P=0.000]、术中出血量减少[(22.35±18.41)vs(3.17±1.69)ml,P=0.000]、术后住院时间缩短[(6.35±0.75)vs(3.61±1.19)d,P=0.000]和术后并发症减少(16 vs 1,P=0.000),两组复发情况差异无统计学意义(1 vs 0,P=0.783)。结论鼻内镜辅助下低温等离子技术治疗鼻前庭囊肿相对于传统唇龈沟入路,具有时间短、创伤小、恢复快、操作简单和疗效好的优势,值得推广。