INTRODUCTIONPancreatic cancer remains the fourth commonest cause of cancer related death in the western world[1]. The prognosis remains dismal due partly to late presentation, with associated low resectability rates, ...INTRODUCTIONPancreatic cancer remains the fourth commonest cause of cancer related death in the western world[1]. The prognosis remains dismal due partly to late presentation, with associated low resectability rates, and the aggressive biological nature of these tumors. The median survival time from diagnosis in unresectable tumors remains only 4 6 months.For those patients amenable to surgical resection over the last 20 years have seen marked improvements in postoperative mortality and morbidity, especially in specialist pancreatic centres 23. Despite these changes long-term survival remains low. with a total 5-year survival rate remaining less than 5%.Patients with ampullary cancer have a better 5-year survival of 40°%-60°%.展开更多
Methods The patients were divided into A,Band C groups:3155 patients (group A)were treated surgically in the first 14 years ,5952 patients (group B)in the next 10 years ,and 3863 patients (group C)in the last 10 years...Methods The patients were divided into A,Band C groups:3155 patients (group A)were treated surgically in the first 14 years ,5952 patients (group B)in the next 10 years ,and 3863 patients (group C)in the last 10 years .The early stage lesions (Tis ,Ti)were as-signed as a separate group.The results of these groups were compared. Results The respectability for esophageal and gastric cardiac carcinoma wsa 94.0% and 84.4% respectively ,and the overall respectability .The overall operative mortality was 1.8%,it was 4.4% for group A, 1.6% for group B,and 0.5% for group C.The overall 5-year sur-vival was 31.6%.The 5-year survival for groups A, B,C and the early stage group was 27.0% ,29.1%,32.0% and 92.6%,respect-tively.Among the 3 temporal groups,differences were observed in tems of lesion stage,location and size,surgery with or without com-bined therapy and postoperative complications. Conclusion Best results were achieved in the early cases,with a respectability of 100% and a 5-year survival of 92.6%.The indications for surgical treatment were extended with increased respectability and decreased mortality.Subtotal esophagectomy combined with cervical esophagogastrostomy was advocated as the procedure of first choice for esophageal carcinoma in attempt to diminish the chance of recur-rence,and to achieve better outcomes by using combined therapy for patients with≥stage Ⅲ lesion.展开更多
Objective: To probe the effect of mastoscopic in modified radical mastectomy operation for preserving nipple-areolar complex in the treatment of breast cancer. Methods: Thirty patients, with breast cancer of a diamete...Objective: To probe the effect of mastoscopic in modified radical mastectomy operation for preserving nipple-areolar complex in the treatment of breast cancer. Methods: Thirty patients, with breast cancer of a diameter≤3 cm and a distance≥3 cm from the mammary areola were treated by mastoscopic from November 2003 to August 2006. After the lipoly- sis and suction of axillary fat, mastoscopic axillary lymph node dissection was performed. Results: The average operation time was 128.9 min (120–156 min), the intraoperative blood loss was 56 mL (30–100 mL). The mean lymph nodes harvested by endoscopy were 16 (6–34). Excellent cosmetic outcomes were obtained with symmetrical breast development and all the patients were satisfied with the treatment. Postoperative follow-up for 2–29 months (mean, 16.6 months) found no local recur-rence. Conclusion:This model of operation can protect the upper limb function and has value of aesthetics of the brisket. What’s more, improve the quality of survive of the patients.展开更多
Objective: To evaluate the treatment effects of total gastrectomy (TG) and proximal gastrectomy (PG) for cancer of the cardia and esophagogastric junction. Methods: forty-five patients with cancer of the cardia and es...Objective: To evaluate the treatment effects of total gastrectomy (TG) and proximal gastrectomy (PG) for cancer of the cardia and esophagogastric junction. Methods: forty-five patients with cancer of the cardia and esophagogastric junc- tion underwent surgical resection. Of them, 29 were treated using proximal gastrectomy and 16 total gastrectomy. The 3-year and 5-year survival rate and the postoperative complication rate and mortality rate were followed up and compared between the two groups. Results: The 3-year and 5-year survival rates of group PG were 44.8% and 20.7%, of group TG were 37.5% and 18.8%, respectively, and the differences were not statistically significant (χ2 = 3.84, P > 0.05; χ2 = 3.89, P > 0.05). The postoperative complication and mortality rate of group PG were 13.7% and 6.8%, of group TG was all 6%, respectively. Conclusion: Proximal and total gastrectomy treatment effects can not significantly influence the prognosis of patients in progressive stage of cancer of cardia and esophagogastric junction.展开更多
文摘INTRODUCTIONPancreatic cancer remains the fourth commonest cause of cancer related death in the western world[1]. The prognosis remains dismal due partly to late presentation, with associated low resectability rates, and the aggressive biological nature of these tumors. The median survival time from diagnosis in unresectable tumors remains only 4 6 months.For those patients amenable to surgical resection over the last 20 years have seen marked improvements in postoperative mortality and morbidity, especially in specialist pancreatic centres 23. Despite these changes long-term survival remains low. with a total 5-year survival rate remaining less than 5%.Patients with ampullary cancer have a better 5-year survival of 40°%-60°%.
文摘Methods The patients were divided into A,Band C groups:3155 patients (group A)were treated surgically in the first 14 years ,5952 patients (group B)in the next 10 years ,and 3863 patients (group C)in the last 10 years .The early stage lesions (Tis ,Ti)were as-signed as a separate group.The results of these groups were compared. Results The respectability for esophageal and gastric cardiac carcinoma wsa 94.0% and 84.4% respectively ,and the overall respectability .The overall operative mortality was 1.8%,it was 4.4% for group A, 1.6% for group B,and 0.5% for group C.The overall 5-year sur-vival was 31.6%.The 5-year survival for groups A, B,C and the early stage group was 27.0% ,29.1%,32.0% and 92.6%,respect-tively.Among the 3 temporal groups,differences were observed in tems of lesion stage,location and size,surgery with or without com-bined therapy and postoperative complications. Conclusion Best results were achieved in the early cases,with a respectability of 100% and a 5-year survival of 92.6%.The indications for surgical treatment were extended with increased respectability and decreased mortality.Subtotal esophagectomy combined with cervical esophagogastrostomy was advocated as the procedure of first choice for esophageal carcinoma in attempt to diminish the chance of recur-rence,and to achieve better outcomes by using combined therapy for patients with≥stage Ⅲ lesion.
文摘Objective: To probe the effect of mastoscopic in modified radical mastectomy operation for preserving nipple-areolar complex in the treatment of breast cancer. Methods: Thirty patients, with breast cancer of a diameter≤3 cm and a distance≥3 cm from the mammary areola were treated by mastoscopic from November 2003 to August 2006. After the lipoly- sis and suction of axillary fat, mastoscopic axillary lymph node dissection was performed. Results: The average operation time was 128.9 min (120–156 min), the intraoperative blood loss was 56 mL (30–100 mL). The mean lymph nodes harvested by endoscopy were 16 (6–34). Excellent cosmetic outcomes were obtained with symmetrical breast development and all the patients were satisfied with the treatment. Postoperative follow-up for 2–29 months (mean, 16.6 months) found no local recur-rence. Conclusion:This model of operation can protect the upper limb function and has value of aesthetics of the brisket. What’s more, improve the quality of survive of the patients.
基金Shanghai Baoshan Science and Technology developing funds (No: 03-A-34)
文摘Objective: To evaluate the treatment effects of total gastrectomy (TG) and proximal gastrectomy (PG) for cancer of the cardia and esophagogastric junction. Methods: forty-five patients with cancer of the cardia and esophagogastric junc- tion underwent surgical resection. Of them, 29 were treated using proximal gastrectomy and 16 total gastrectomy. The 3-year and 5-year survival rate and the postoperative complication rate and mortality rate were followed up and compared between the two groups. Results: The 3-year and 5-year survival rates of group PG were 44.8% and 20.7%, of group TG were 37.5% and 18.8%, respectively, and the differences were not statistically significant (χ2 = 3.84, P > 0.05; χ2 = 3.89, P > 0.05). The postoperative complication and mortality rate of group PG were 13.7% and 6.8%, of group TG was all 6%, respectively. Conclusion: Proximal and total gastrectomy treatment effects can not significantly influence the prognosis of patients in progressive stage of cancer of cardia and esophagogastric junction.
