Tuberculosis has global presence and no part of human body is immune to it,most frequent site beings lungs.Nasopharyngeal tuberculosis is a rare type oJ extrapulmonary tuberculosis comprising onlv less than 1%of tuber...Tuberculosis has global presence and no part of human body is immune to it,most frequent site beings lungs.Nasopharyngeal tuberculosis is a rare type oJ extrapulmonary tuberculosis comprising onlv less than 1%of tuberculosis found in the upper respiratory tract.The authors are presenting here a case of primary tubereulousis affecting the nasopharynx(adenoids) which is one of the rare differential diagnosis of nasopharyngeal mass.Isolated nasopharyngeal tuberculosis is a rare condition even in the endemic areas.In literature there are varied clinical presentations of nasopharyngeal luberculosis.Tuberculosis should be one of the differential diagnosis of nasopharyngeal lesion.Biopsy and histologic study should be performed in every patient to avoid misdiagnosis.When treated properly,nasopharyngeal luberculosis carries a excellent progno.sis,and complete resolution of disease is the rule.展开更多
Background: Tuberculosis (TB) of the nose and nasopharynx are rare localizations for tuberculosis to manifest. Aim: We hope to present a case of tuberculosis of the nasopharynx and its rare presentation. Case presenta...Background: Tuberculosis (TB) of the nose and nasopharynx are rare localizations for tuberculosis to manifest. Aim: We hope to present a case of tuberculosis of the nasopharynx and its rare presentation. Case presentation: This patient presented with a long standing history of headache and neck pain prior to being seen. Imaging showed a mass at the nasopharynx and a biopsy con-firmed tuberculosis. Patient was initiated on anti-tuberculosis therapy with improvement in her symptoms on follow up. Conclusion: A high index of suspicion is imperative for early diagnosis.展开更多
A tumor-like presentation of systemic amyloidosis in the nasopharynx is exceedingly rare. A male of 52-year-old with a recurrent mass in the nasopharynx underwent surgical resection 2 years ago. Immunohistochemical ex...A tumor-like presentation of systemic amyloidosis in the nasopharynx is exceedingly rare. A male of 52-year-old with a recurrent mass in the nasopharynx underwent surgical resection 2 years ago. Immunohistochemical examination revealed M protein band and kappa immunoglobulin light chain. The sections of the biopsy of the mass in the nasopharynx and anterior abdominal wall were stained with Congo red and examined with microscopy. Amyloid deposits were found. It was diagnosed as systemic amyloidoma. Colchicine, melphalan and prednisone were administered. The mass decreased its size in the 8 months of follow-up. This case suggests that a solitary tumor in the nasopharynx might be an early sign of systemic amyloidosis because of the slow progression of the disease. The existence of a solitary amyloidoma in any location of the body should lead the doctor to look for other symptoms and signs of systemic amyloidosis.展开更多
Primary salivary gland-type carcinoma of the nasopharynx is a rare malignancy with aggressive clinical behavior and poor prognosis. Few cases have been reported in the literature. We report the case of a salivary glan...Primary salivary gland-type carcinoma of the nasopharynx is a rare malignancy with aggressive clinical behavior and poor prognosis. Few cases have been reported in the literature. We report the case of a salivary gland-type carcinoma of the nasopharynx diagnosed in a 70-year-old woman managed in department of radiotherapy at Hassan II University Hospital in Morocco. The patient received a total of 70 Gy of radiations, which were divided into 2 Gy per session during 7 weeks. Follow-up was performed regularly, including nasal endoscopic examination and nasopharyngeal CT. Evolution was marked by disease control after 12 months of follow-up. The aim of this work is to show the rarity of this entity, describe clinical, radiological and histological features and finally discuss the treatment management.展开更多
Oncocytic metaplasia is a well-established pathological entity that may occur in many organs;including salivary glands, thyroid, parathyroid and kidney. The occurrence of oncocytic metaplasia in the nasopharynx is unc...Oncocytic metaplasia is a well-established pathological entity that may occur in many organs;including salivary glands, thyroid, parathyroid and kidney. The occurrence of oncocytic metaplasia in the nasopharynx is uncommon and metaplasia with melanin pigmentation is extremely rare, no more than twenty cases having been reported to date.展开更多
Nasopharyngeal liposarcoma is an extremely rare clinical entity. Less than ten cases have been reported in the literature. It mainly occurs in humans. The non-specificity of the clinical and radiological signs explain...Nasopharyngeal liposarcoma is an extremely rare clinical entity. Less than ten cases have been reported in the literature. It mainly occurs in humans. The non-specificity of the clinical and radiological signs explains the difficulty of the diagnosis confirmed by anatomopathological and immunohistochemical examinations. Its pathogenesis remains obscure and often correlates with genetic abnormalities. Pleomorphic liposarcoma is its rarest subtype, remarkable for its aggressiveness and rapidity of growth. Complete surgical excision remains the treatment of choice. We report a case of liposarcoma whose diagnosis was made during histological examination coupled with immunohistochemistry. .展开更多
目的探讨骨科住院患者的金黄色葡萄球菌(staphylococcus aureus,SA)和耐甲氧西林金黄色葡萄球菌(methicillin-resistant staphylococcus aureus,MRSA)定植特点及其与术后手术切口感染(surgical site infections,SSI)的相关性,并分析影...目的探讨骨科住院患者的金黄色葡萄球菌(staphylococcus aureus,SA)和耐甲氧西林金黄色葡萄球菌(methicillin-resistant staphylococcus aureus,MRSA)定植特点及其与术后手术切口感染(surgical site infections,SSI)的相关性,并分析影响定植的相关因素。方法采集2020年1月~2022年10月在浙江省立同德医院骨科住院的420例患者的鼻拭子和咽拭子标本,使用聚合酶链反应(polymerase chain reaction,PCR)法检测SA和MRSA阳性定植情况,获取患者的临床资料,采用χ^(2)检验分析SA阳性定植与术后SSI的相关性,采用单因素和多因素Logistic回归分析探讨影响SA定植的相关因素。结果420例患者中,19例患者SA检测阳性,总体SA定植阳性率为4.5%。19例中有17例患者同时呈MRSA检测阳性,MRSA定植阳性率为4.0%。SA定植阳性者与定植阴性者术后发生SSI比较,差异无统计学意义(P>0.05),SA与术后SSI的发生无明显相关性。单因素Logistic回归分析结果显示,年龄、体重指数(body mass index,BMI)是SA定植的影响因素,多因素Logistic回归分析结果显示,BMI是SA定植的危险因素,BMI越大定植风险越高。年龄是SA定植的保护因素,随着年龄增大SA定植风险降低。结论骨科住院患者SA阳性定植不会增加术后SSI的风险,术前进行增加患者医疗成本的SA去定植措施是没有必要的。BMI是骨科住院患者SA定植的危险因素,年龄是其保护因素。骨科住院患者SA定植具有区域属性,每个区域需要根据本地域的SA定植流行病学特点制定医疗方案。展开更多
罗道病（Rosai-Dorfman病）又称窦组织细胞增生伴巨大淋巴结病（sinus hisliocytosis with massive lymphadenopathy,SHML）是一种良性淋巴组织增生性疾病，1966年Azoury和Reed首先报道，1969年Rosai和Dorfman对其做了详细研究，并正式...罗道病（Rosai-Dorfman病）又称窦组织细胞增生伴巨大淋巴结病（sinus hisliocytosis with massive lymphadenopathy,SHML）是一种良性淋巴组织增生性疾病，1966年Azoury和Reed首先报道，1969年Rosai和Dorfman对其做了详细研究，并正式命名。展开更多
文摘Tuberculosis has global presence and no part of human body is immune to it,most frequent site beings lungs.Nasopharyngeal tuberculosis is a rare type oJ extrapulmonary tuberculosis comprising onlv less than 1%of tuberculosis found in the upper respiratory tract.The authors are presenting here a case of primary tubereulousis affecting the nasopharynx(adenoids) which is one of the rare differential diagnosis of nasopharyngeal mass.Isolated nasopharyngeal tuberculosis is a rare condition even in the endemic areas.In literature there are varied clinical presentations of nasopharyngeal luberculosis.Tuberculosis should be one of the differential diagnosis of nasopharyngeal lesion.Biopsy and histologic study should be performed in every patient to avoid misdiagnosis.When treated properly,nasopharyngeal luberculosis carries a excellent progno.sis,and complete resolution of disease is the rule.
文摘Background: Tuberculosis (TB) of the nose and nasopharynx are rare localizations for tuberculosis to manifest. Aim: We hope to present a case of tuberculosis of the nasopharynx and its rare presentation. Case presentation: This patient presented with a long standing history of headache and neck pain prior to being seen. Imaging showed a mass at the nasopharynx and a biopsy con-firmed tuberculosis. Patient was initiated on anti-tuberculosis therapy with improvement in her symptoms on follow up. Conclusion: A high index of suspicion is imperative for early diagnosis.
文摘A tumor-like presentation of systemic amyloidosis in the nasopharynx is exceedingly rare. A male of 52-year-old with a recurrent mass in the nasopharynx underwent surgical resection 2 years ago. Immunohistochemical examination revealed M protein band and kappa immunoglobulin light chain. The sections of the biopsy of the mass in the nasopharynx and anterior abdominal wall were stained with Congo red and examined with microscopy. Amyloid deposits were found. It was diagnosed as systemic amyloidoma. Colchicine, melphalan and prednisone were administered. The mass decreased its size in the 8 months of follow-up. This case suggests that a solitary tumor in the nasopharynx might be an early sign of systemic amyloidosis because of the slow progression of the disease. The existence of a solitary amyloidoma in any location of the body should lead the doctor to look for other symptoms and signs of systemic amyloidosis.
文摘Primary salivary gland-type carcinoma of the nasopharynx is a rare malignancy with aggressive clinical behavior and poor prognosis. Few cases have been reported in the literature. We report the case of a salivary gland-type carcinoma of the nasopharynx diagnosed in a 70-year-old woman managed in department of radiotherapy at Hassan II University Hospital in Morocco. The patient received a total of 70 Gy of radiations, which were divided into 2 Gy per session during 7 weeks. Follow-up was performed regularly, including nasal endoscopic examination and nasopharyngeal CT. Evolution was marked by disease control after 12 months of follow-up. The aim of this work is to show the rarity of this entity, describe clinical, radiological and histological features and finally discuss the treatment management.
文摘Oncocytic metaplasia is a well-established pathological entity that may occur in many organs;including salivary glands, thyroid, parathyroid and kidney. The occurrence of oncocytic metaplasia in the nasopharynx is uncommon and metaplasia with melanin pigmentation is extremely rare, no more than twenty cases having been reported to date.
文摘Nasopharyngeal liposarcoma is an extremely rare clinical entity. Less than ten cases have been reported in the literature. It mainly occurs in humans. The non-specificity of the clinical and radiological signs explains the difficulty of the diagnosis confirmed by anatomopathological and immunohistochemical examinations. Its pathogenesis remains obscure and often correlates with genetic abnormalities. Pleomorphic liposarcoma is its rarest subtype, remarkable for its aggressiveness and rapidity of growth. Complete surgical excision remains the treatment of choice. We report a case of liposarcoma whose diagnosis was made during histological examination coupled with immunohistochemistry. .
文摘目的探讨骨科住院患者的金黄色葡萄球菌(staphylococcus aureus,SA)和耐甲氧西林金黄色葡萄球菌(methicillin-resistant staphylococcus aureus,MRSA)定植特点及其与术后手术切口感染(surgical site infections,SSI)的相关性,并分析影响定植的相关因素。方法采集2020年1月~2022年10月在浙江省立同德医院骨科住院的420例患者的鼻拭子和咽拭子标本,使用聚合酶链反应(polymerase chain reaction,PCR)法检测SA和MRSA阳性定植情况,获取患者的临床资料,采用χ^(2)检验分析SA阳性定植与术后SSI的相关性,采用单因素和多因素Logistic回归分析探讨影响SA定植的相关因素。结果420例患者中,19例患者SA检测阳性,总体SA定植阳性率为4.5%。19例中有17例患者同时呈MRSA检测阳性,MRSA定植阳性率为4.0%。SA定植阳性者与定植阴性者术后发生SSI比较,差异无统计学意义(P>0.05),SA与术后SSI的发生无明显相关性。单因素Logistic回归分析结果显示,年龄、体重指数(body mass index,BMI)是SA定植的影响因素,多因素Logistic回归分析结果显示,BMI是SA定植的危险因素,BMI越大定植风险越高。年龄是SA定植的保护因素,随着年龄增大SA定植风险降低。结论骨科住院患者SA阳性定植不会增加术后SSI的风险,术前进行增加患者医疗成本的SA去定植措施是没有必要的。BMI是骨科住院患者SA定植的危险因素,年龄是其保护因素。骨科住院患者SA定植具有区域属性,每个区域需要根据本地域的SA定植流行病学特点制定医疗方案。
文摘罗道病（Rosai-Dorfman病）又称窦组织细胞增生伴巨大淋巴结病（sinus hisliocytosis with massive lymphadenopathy,SHML）是一种良性淋巴组织增生性疾病，1966年Azoury和Reed首先报道，1969年Rosai和Dorfman对其做了详细研究，并正式命名。
