Progress in neurorehabilitation research and the support by the National Natural Science Foundation of China from 2010 to 2022

The National Natural Science Foundation of China is one of the major funding agencies for neuro rehabilitation research in China.This study reviews the frontier directions and achievements in the field of neurorehabilitation in China and wo rldwide.We used data from the Web of Science Core Collection(WoSCC) database to analyze the publications and data provided by the National Natural Science Foundation of China to analyze funding information.In addition,the prospects for neurorehabilitation research in China are discussed.From 2010 to 2022,a total of 74,220 publications in neurorehabilitation were identified,with there being an overall upward tendency.During this period,the National Natural Science Foundation of China has funded 476 research projects with a total funding of 192.38 million RMB to support neuro rehabilitation research in China.With the support of the National Natural Science Foundation of China,China has made some achievements in neurorehabilitation research.Research related to neurorehabilitation is believed to be making steady and significant progress in China.

Aortic Dissection Research in China:Analysis of Studies Funded by the National Natural Science Foundation of China

Objective The National Natural Science Foundation of China(NSFC)has made great progress in promoting the development of aortic dissection research in recent years.This study aimed to examine the development and research status of aortic dissection research in China so as to provide references for future research.Methods The NSFC projects data from 2008 to 2019 were collected from the Internet-based Science Information System and other websites utilized as search engines.The publications and citations were retrieved by Google Scholar,and the impact factors were checked by the InCite Journal Citation Reports database.The investigator’s degree and department were identified from the institutional faculty profiles.Results A total of 250 grant funds totaling 124.3 million Yuan and resulting in 747 publications were analyzed.The funds in economically developed and densely populated areas were more than those in underdeveloped and sparsely populated areas.There was no significant difference in the amount of funding per grant between different departments’investigators.However,the funding output ratios of the grants for cardiologists were higher than those for basic science investigators.The amount of funding for clinical researchers and basic scientific researchers in aortic dissection was also similar.Clinical researchers were better in terms of the funding output ratio.Conclusion These results suggest that the medical and scientific research level of aortic dissection in China has been greatly improved.However,there are still some problems that urgently need to be solved,such as the unreasonable regional allocation of medical and scientific research resources,and the slow transition from basic science to clinical practice.

The 2010–2020 National Natural Science Foundation of China:Radiation Therapy

Objective This study explains the application number and funding rate of oncology projects undertaken by the National Natural Science Foundation of China(NSFC),with focus on tumor radiotherapy-related research over the past 11 years.Methods A stratified analysis was carried out on the application and funding status of tumor radiotherapy studies in different NSFC project categories,different research areas,and different tumor types.Research areas that required specific focus,such as immunology-related radiotherapy,multimodality imaging and radiomics,and post-radiotherapy organ injury,were separately analyzed.Results The status and development trends of various related research fields were studied,and the research results were presented with the support of the NSFC,in order to provide reference for future applications and funding allocations.Conclusion The number of applications for funding increases every year.Although the total number of funded projects has also increased every year,the funding rate has decreased year by year.Projects on radiotherapy and immunization have been at the forefront in recent years,and the funding rate for these projects increases yearly.

LIRR's Project of “Study on Spalling Mechanism Mechanism of Dense Refractory Castables by Rapid Heating-up” Being Obtained the Support from National Natural Natural Science Foundation of China

LIRR＇s Priject of ＂Research on Spalling Mechanism Due to Rapid Heating-up of Dense Refractory Castables＂ declared by Wang Zhanmin,vice-president of LIRR,will gain the fund support from National Natural Science Foundation of China in 2011.

2022年NSFC心血管领域中、西医申请资助情况分析

系统梳理分析2022年国家自然科学基金心血管领域中、西医学面上项目、青年科学基金项目和地区科学基金项目3类常规项目的申请和资助情况、所涉及主要病种、研究热点和研究思路。结果显示,两个领域研究的主要病种相似,研究热点也基本一致。均以动脉粥样硬化、冠心病、心力衰竭、高血压、继发性心肌损伤和心律失常为主,主要开展表观遗传学、外泌体、细胞焦亡或铁死亡、细胞自噬、肠道微生物群以及线粒体功能方面的研究,思路呈现多样化的特点。但西医心血管领域的病种更为广泛,还包括心脏移植等中医心血管领域不涉及的病种。在科学问题导向和研究内容方面,中医心血管领域要求在中医药理论的指导下,以解决中医学科的关键科学问题为导向,体现中医药的特色。此外,研究热点只是探索科学问题的技术手段,应深入凝练科学问题,避免盲目追求结合研究热点反而缺乏了创新性思想和科学依据,鼓励原创性基础研究。

InCites视角的山东省NSFC资助论文产出研究

对基金论文的研究可以了解地区的科研水平和竞争力,同时把握基金资助的效果。以InCites数据库提取到的2018—2022年国家自然科学基金(National Natural Science Foundation of China,NSFC)资助的山东省论文为研究对象,从基金论文的产出数量、产出机构、影响力、期刊分布、国际合作、横向对比等多个维度进行分析,一定程度上揭示了山东省NSFC资助论文产出的整体情况。建议发挥高校基础研究主力军作用,注重人才培养,推动科技合作,加强地区基础研究竞争力,争取更多基金资助,提升资助效能。

Viewing the current situation of pig model application in China’s medical field from the application and funding of NSFC

Background:The National Natural Science Foundation of China(NSFC)is an important part of China’s innovation system.In the last decade,the pig has become more and more widely used in the field of medical science,especially in otology research.Objective:By analyzing and summarizing the funding information over recent years,we intend to identify the characteristics and trends of funding for research using pig models and provide references for future development.Material and methods:This is a comprehensive analysis of features in funding for research projects involving pig models by the NSFC in the past 10 years,with a focus on projects in the field of otolaryngology/head and neck surgery.Results:Both the number and amount of funding provided by the NSFC for research involving pig models are on the rise with each passing year.Researchers at the PLA General Hospital have completed a number of studies using miniature pigs in cochlear morphology,electrophysiology,cochlear implantation,cochlear transcription analysis,gene therapy,inner ear disease modeling and Eustachian tube pathology modeling.Conclusion:Pigs as an ideal large mammal model are well suited in the current national basic research strategy in China,and can help further strengthen China’s leading position in basic research in the world.

Mapping scientific cooperation of the NSFC:A case study of Major International(Regional) Joint Research Program

International cooperations have played an important role in academic activities as more and more researchers endeavor to participate in joint research or exchange with partners aboard. Focused on projects of Major International(Regional) Joint Research Program of the Natural Science Foundation of China(NSFC) from 2003 to 2008, we have investigated the characteristics of the scientific cooperation by mapping the funded projects from the aspects of topics, affiliations and cooperative countries(regions), respectively.Moreover, it is demonstrated that issues related to nano technologies, genes and ecological environments have become the hot topics in the joint research of NSFC, and projects with issues of big science have been preferentially funded under the program’s guide posted every year. Moreover, most granted projects were undertaken by the minority of affiliations with the leading research capability, which is the same to partners abroad. The aggregation effect has been greatly improved with the bilateral or multilateral agreement signed with scientific organizations abroad, so has the competitive mechanism of scientific resources allocation.

2017—2022年度NSFC智能电网联合基金重点技术方向与资助对象分析

该文针对国家自然科学基金智能电网联合基金(含企业创新联合发展基金–新型电力系统领域)2017—2022年度获批项目开展统计分析,在技术领域、项目名称、牵头单位情况等方面进行特征剖析和总结提炼。结果表明,联合基金资助项目研发重点呈现逐年动态调整特征,充分体现了学科发展及行业转型的双重需求,其中大电网安全、设备运行维护、配电等传统业务领域仍为联合基金资助的重点,同时该基金也对综合能源、人工智能、储能等可能对未来电网发展产生颠覆性影响的技术进行积极跟踪。国家电网公司直属科研单位和高校、中科院等研究机构在不同技术领域的实力呈现个性化特点,未来新型电力系统构建有待各类主体发挥各自优势,协同创新。

Remarkable achievements in orogenic belt research——An introduction to a fulfilled program supported by the National Natural Science Foundation of China (NSFC)

THE continental dynamics has become a goaI since the beginning of the 1990s and it will still bethe key subject in the 21st century. Orogenic belts, having experienced the most intensechanges of geotherm and mechanics in the lithosphere, are the important research object in thestudy of continental dynamics. For this reason, the study of orogenic belts forms a hot and dif-ficult point in the geological society and the concentration of efforts is needed for overcomingthis difficult point. China has the most orogenic belts of various types in the world, so the De-partment of Earth Sciences caught this scientific chance in the early 1990s, took the

2023年度地球科学部基金项目评审工作综述

本文总结了2023年度国家自然科学基金委员会地球科学部的评审工作,分析了地球科学部各类项目受理、评审和资助情况,梳理了深化科学基金改革实施情况,提出了下一年度科学基金工作思路。

2023年度工程与材料科学部基金项目评审工作综述

本文总结了2023年度国家自然科学基金委员会工程与材料科学部项目评审工作情况,对各类项目申请、受理、评审和资助情况进行了整理及分析,重点回顾了本年度工程与材料科学部深化科学基金改革新举措及实施成效,并提出了下一年度评审工作的思路及建议,以进一步提高工程与材料科学基础研究资助质量。

2023年度生命科学部科学基金项目评审工作综述

本文总结了2023年度生命科学部各类科学基金项目评审情况,梳理了本年度科学基金深化改革的实施情况,并提出下一年度项目评审的工作思路。

某神经特色医疗机构2020—2023年申请神经系统领域国家自然科学基金项目同行评议意见分析及对策

目的了解首都医科大学附属北京天坛医院神经系统领域国家自然科学基金项目申请未获资助的原因并提出对策,为同行提供借鉴。方法采用内容分析法,对该医院2020—2023年申请国家自然科学基金神经系统领域未获资助的289项青年、面上项目的867人次同行评议意见进行归类整理分析。结果本文共分析了1219条未获资助原因,发现在未获资助的青年和面上项目中,存在问题提及率及比例排名前5位的依次为“研究方案不合理”(32.65%/85.12%)、“研究基础不足”(18.54%/54.33%)、“创新性不足”(15.67%/51.21%)、“立项依据不足”(8.37%/30.10%)、“科学及临床价值不足”(7.88%/28.72%),其中青年项目“创新性不足”(提及率:17.13%vs.13.84%;比例:53.75%vs.48.06%)、“细节问题”(提及率:6.50%vs.3.87%;比例:23.13%vs.15.50%)的提及率及比例略高于面上项目,“科学问题属性选择错误”的提及率(4.28%vs.4.06%)、“关键科学问题凝练不足”的比例(24.38%vs.23.26%)同样在青年项目中略高,但仅“细节问题”提及率在两类项目中的差异有统计学意义(χ^(2)=4.322,P=0.038)。专家意见一致性分析显示,3位专家意见完全一致且排名前3位的反馈意见与上述结果中的前3位一致。结论该医院未中标项目存在问题主要集中在“研究方案不合理”“研究基础不足”“创新性不足”3个方面。建议该医院通过开展多维度的申报培训、精细化辅导等方式帮助申请人完善方案设计,通过设立孵育基金、加强在研课题过程管理等渠道强化研究基础,通过促进学科交叉融合拓展研究领域和思路、提升源头创新能力等措施提高申请书质量及申请中标率。

天津某医院国家自然科学基金管理模式的实践探索与效果评价

目的分析天津医科大学总医院国家自然科学基金情况,评价国家自然科学基金管理模式实践探索的效果。方法选取天津医科大学总医院2019年3月至2024年3月国家自然科学基金申报与获批等项目为研究对象,于2022年4月开始实施完善科技人才体系、加强培育辅导、提高项目支撑及营造科研生态的管理,比较管理前后的国家自然科学基金申报数、获批项目数和中标率,评价管理模式的效果。结果2023年,天津医科大学总医院共获批44项国家自然科学基金,较2022年增长22.22%;获批31项国家自然科学基金青年科学基金,较2022年增长138.50%;国家自然科学基金青年科学基金中标率为15.66%,较2022年增长133.70%。2024年相比2023年,申报国家自然科学基金为425项,增长75项,增长率高达21.43%;其中面上项目为213项,增长74项,增长率高达53.24%。近5年,天津医科大学总医院国家自然科学基金获批项目分布于全院34个科室,其中神经外科18项、神经内科17项及神经所17项等。天津医科大学总医院国家自然科学基金青年科学基金获批项目分布于31个科室,其各科室获批项目数与国家自然科学基金存在不一致性。结论目前采取的基金管理模式有助于医院国家自然科学基金水平的提升,特别是利于青年科技人才的培养。今后还需从下沉科室+精准服务,做到针对性管理;进一步加强新职工培训,促进后备人才成长;落实科研课题过程管理,用好“前一桶金”等方面加以提升。

2016-2020年NSFC资助的(H.3201)中药资源科学项目概况及热点分析

目的:探讨2016-2020年国家自然科学基金中药资源科学资助总体情况以及研究热点,以期为中药资源科学基础研究的进一步发展提供参考。方法:通过“八爪鱼采集器(V8.2.2.111911版本)”采集国家自然科学基金查询网、国家自然科学基金项目查询网2016-2020年申请代码为H.3201(中药资源)资助项目所有信息,采用Excel2016数据透视表及透视图分析年度立项项目资助数量、金额、依托单位等,以及通过BDP个人版官方网站对立项省份分布作图展示,并通过PyCharm Community Edition软件撰写jieba分词代码及Microsoft Word2016的宏代码程序对项目名称进行分词,并将研究对象、项目名称词频结果导入Word Art官方网站在线热点词云图绘制以分析研究热点。结果:2016-2020年NSFC中药资源科学领域资助项目数量、金额总体呈轻微下降趋势;项目类别以面上项目和青年科学基金项目为主,依托单位以高等院校为主,资助地域总体布局较广,但呈现出地域发展不平衡的态势。研究对象词汇出现较大比重的有:丹参、人参、三七、地黄、铁皮石斛、白木香、甘草、当归、党参、广藿香等。标题词汇出现较大比重的有:机制、调控、分子、品质、生物合成、转录因子等。结论:2016-2020年NSFC资助的中药资源领域研究立项项目数量及金额略下降,主要集中在高等院校,立项地区发展呈现不均衡,丹参、人参、三七等是重点研究对象,中药生物合成与调控、中药资源品质与评价、转录因子等是研究热衷领域,有学科交叉特点。建议广大学者从药性理论为切入点,多组学技术手段,从生物学、生态学、分子生物学等角度科学研究分析,全方位、多层次推进中药资源基础研究,且应注重中药理论及技术方法的原始创新。

医院国家自然科学基金项目获批影响因素分析及预测模型构建

目的探究医院进行国家自然科学基金管理的有效策略。方法回顾性分析某三甲综合性医院2016—2022年度国家自然科学基金项目申报和获批的情况,运用单因素分析及二分类多因素Logistic回归分析影响国家自然科学基金项目获批的因素并建立函数预测模型。结果本研究共收集了1098位申请人的数据信息,其中青年项目申请人653人,获批178人;面上项目申请人445人,获批114人;多因素Logistic结果显示,在青年项目中,年龄越小、有博士学位、是科研岗位、有海外留学经历、以第一/通讯作者身份发表SCI论文平均影响因子在3~5分、以第一/通讯作者身份发表SCI论文平均影响因子在5分以上、以第一/通讯作者发表4区SCI论文、主持过国家级和院校级课题的申请人更易获批国家自然科学基金青年项目;在面上项目中,有博士学位、有海外留学经历、以第一/通讯作者发表1区和2区SCI论文、主持过国家级课题的申请人更易获批国家自然科学基金面上项目。青年项目回归预测模型AUC曲线下面积为0.860,面上项目回归预测模型AUC曲线下面积为0.838,模型的预测价值较高。结论医院应通过强化政策引导,加大经济投入,提倡申请人进行前期工作布局,聚焦人才培养等途径,全面促进医院国家自然科学基金的有效管理。

国家自然科学基金青年科学基金项目立项的影响因素分析——以上海交通大学医学院为例

目的·基于医学领域国家自然科学基金青年科学基金项目资助率低的现状,对项目申请人展开深入调查,定量分析项目立项的影响因素,为进一步提升项目申报质量、加强青年医学人才培养提供数据参考和决策依据。方法·采用横断面调查法,选取上海交通大学医学院各二级学院及13所附属医院在2020—2022年有国家自然科学基金青年科学基金项目申报经历的申请人进行问卷调查,以项目申请结果为因变量,以申请人基本情况和申报情况等为自变量,通过Logistic逐步回归模型建模与分析。结果·对921名项目申请者的分析结果显示,学历(OR=1.86,95%CI1.14~3.04)、毕业院校(OR=2.45,95%CI 1.47~4.08)、有较为充分的前期工作基础(OR=4.22,95%CI 2.44~7.29)、代表作平均影响因子(OR=1.10,95%CI1.04~1.17)、申请书自评总分(OR=1.06,95%CI1.04~1.08)是项目立项的主要影响因素。且项目获批者代表作平均影响因子和最高影响因子呈逐年递增的趋势。此外,青年医师和专职科研人员项目获批的影响因素不同,青年医师的毕业时间越长,获批率越低。结论·青年科学基金项目资助率低下,对科研成果的要求逐年提升,应注重前期积累,提高申请书撰写质量,并进一步采取措施,加强青年医学人才早期培养,完善分类培养举措,着力夯实研究基础。