A new nonlinear optical third\|harmonic imaging technology in reflected fashion in bio\|tissues by using cascading effect, a process whereby the second\|order effects combine to contribute to a...A new nonlinear optical third\|harmonic imaging technology in reflected fashion in bio\|tissues by using cascading effect, a process whereby the second\|order effects combine to contribute to a third\|order nonlinear process, has been analyzed. The performance of the reflected optical third harmonic imaging enhanced by cascading effect in bio\|tissues is analyzed with the semi\|classical theory. The microscopic understanding of the enhancement of cascaded optical third\|harmonic imaging in reflected manner in bio\|tissues has been discussed.Some i deas for further enhancement is given.展开更多
Objectives: To directly compare the quality of harmonic imaging (HI) and fundamental imaging (FI) in fetal echocardiography and to determine any differences in image quality between the two modalities. Methods: Feta...Objectives: To directly compare the quality of harmonic imaging (HI) and fundamental imaging (FI) in fetal echocardiography and to determine any differences in image quality between the two modalities. Methods: Fetal echocardiograms were performed with the use of FI and HI in 58 fetuses, image quality and visualization of left and right atria, left and right ventricles, mitral and tricuspid valves, aortic and pulmonary valves, left and right ventricular outflow tracts were evaluated and compared between FI and HI. Results: Mean HI scores were higher than mean FI scores (2.73±0.43 vs 2.16±0.69, P <0.001)for all the cardiovascular structures evaluated. Compared with FI, HI improved the image quality and visualization of fetal cardiac structures in subjects with both good (2.73±0.43 vs 2.88±0.32, P <0.001) and suboptimal (1.65±0.41 vs 2.58±0.47, P <0.001) echocardiographic windows. The interobserver correlation coefficient for the grading scores was 0.74 ( P <0.001). Conclusions: harmonic imaging enhances and improves the image quality of fetal echocardiography; and has important potential role in cardiac imaging in the fetus.展开更多
In this paper, a phase-coded pulse technique is proposed to improve the signal-to-noise ratio (SNR) in the 3rd harmonic imaging in transmis-sion mode, where three pulses with initial phases of 0o, 120o and 240o are tr...In this paper, a phase-coded pulse technique is proposed to improve the signal-to-noise ratio (SNR) in the 3rd harmonic imaging in transmis-sion mode, where three pulses with initial phases of 0o, 120o and 240o are transmitted and their corre-sponding received signals are linearly summed. By means of simulations and measurements, we show that the 3rd harmonic is enhanced by 9.5 dB, whereas the fundamental or the 2nd harmonic components are suppressed; the axial and lateral beam profiles of the processed 3rd harmonics are superior to those of the fundamental or 2nd harmonic components. In addition, this technique is applied to obtain the 3rd harmonic images for two normal and pathological biological tissues in transmission mode. This technique yields a dramatically cleaner and sharper contrast than the images obtained by the traditional fundamental im-aging and the 2nd harmonic imaging, which helps distinguish the normal and pathological states of tis-sues.展开更多
文摘A new nonlinear optical third\|harmonic imaging technology in reflected fashion in bio\|tissues by using cascading effect, a process whereby the second\|order effects combine to contribute to a third\|order nonlinear process, has been analyzed. The performance of the reflected optical third harmonic imaging enhanced by cascading effect in bio\|tissues is analyzed with the semi\|classical theory. The microscopic understanding of the enhancement of cascaded optical third\|harmonic imaging in reflected manner in bio\|tissues has been discussed.Some i deas for further enhancement is given.
文摘Objectives: To directly compare the quality of harmonic imaging (HI) and fundamental imaging (FI) in fetal echocardiography and to determine any differences in image quality between the two modalities. Methods: Fetal echocardiograms were performed with the use of FI and HI in 58 fetuses, image quality and visualization of left and right atria, left and right ventricles, mitral and tricuspid valves, aortic and pulmonary valves, left and right ventricular outflow tracts were evaluated and compared between FI and HI. Results: Mean HI scores were higher than mean FI scores (2.73±0.43 vs 2.16±0.69, P <0.001)for all the cardiovascular structures evaluated. Compared with FI, HI improved the image quality and visualization of fetal cardiac structures in subjects with both good (2.73±0.43 vs 2.88±0.32, P <0.001) and suboptimal (1.65±0.41 vs 2.58±0.47, P <0.001) echocardiographic windows. The interobserver correlation coefficient for the grading scores was 0.74 ( P <0.001). Conclusions: harmonic imaging enhances and improves the image quality of fetal echocardiography; and has important potential role in cardiac imaging in the fetus.
文摘In this paper, a phase-coded pulse technique is proposed to improve the signal-to-noise ratio (SNR) in the 3rd harmonic imaging in transmis-sion mode, where three pulses with initial phases of 0o, 120o and 240o are transmitted and their corre-sponding received signals are linearly summed. By means of simulations and measurements, we show that the 3rd harmonic is enhanced by 9.5 dB, whereas the fundamental or the 2nd harmonic components are suppressed; the axial and lateral beam profiles of the processed 3rd harmonics are superior to those of the fundamental or 2nd harmonic components. In addition, this technique is applied to obtain the 3rd harmonic images for two normal and pathological biological tissues in transmission mode. This technique yields a dramatically cleaner and sharper contrast than the images obtained by the traditional fundamental im-aging and the 2nd harmonic imaging, which helps distinguish the normal and pathological states of tis-sues.
