Rituximab as a treatment for human immunodeficiency virusassociated nemaline myopathy:What does the literature have to tell us?

We presented a letter about a case of a 37-year-old Black female with a history of human immunodeficiency virus and an undetectable viral load.She was evaluated with weakness in the scapular(grade III)and pelvic girdles(grade II),elevation of creatine phosphokinase levels and muscle biopsy compatible with nemaline myopathy.She was treated with rituximab showing improvement of the condition.

线状体肌病的临床及超微病理学特征(附1例报道)

目的探讨线状体肌病的临床特点、病理学特征。方法结合近3年国外文献复习,分析1例线状体肌病患者的临床特点和超微病理学特征。结果患者3岁发病,症状逐渐加重,病程逾20年,表现为典型的肌张力减低和肢体无力,症状以双下肢为主,近端和远端同时受累,伸肌为著,远端为甚,肌萎缩明显;病理检查发现线状小体、肌膜皱缩、肌纤维断裂,α和β颗粒以及一小块变性的神经纤维束。结论线状体肌病可累及全身骨骼肌,临床表现为肌张力减低和肌无力,病理学特征为线状小体。