A cross sectional epidemiological study of 93 arc welders in a shipyard was conducted to observe the adverse effect of exposure to manganese welding fumes. Among them, 37 workers with paired controls were given the ne...A cross sectional epidemiological study of 93 arc welders in a shipyard was conducted to observe the adverse effect of exposure to manganese welding fumes. Among them, 37 workers with paired controls were given the neurobehavioral tests. Air concentration of manganese in working place, hair manganese and platelet 5 hydroxytryptamine in both exposed workers and controls was also measured. The higher percentage of respiratory symptoms including sour throat and dyspnea in the welders were observed as compared with the controls. The results of neurobehavioral tests showed that the welders exhibited poorer performance in simple reaction time and Santa Ana dexterity tests than that in the controls. The hair manganese concentration was higher and the blood platelet 5 HT level decreased in the welders. In conclusion, symptoms in the welders might be related to the exposure of manganese. Long term exposure to manganese welding fume could cause the change in simple reaction time and Santa Ana dexterity tests. The hair manganese concentration could be used as a biological monitoring index of exposure to manganese.展开更多
Exposure to mercury can cause immune, sensory, neurological, motor and behavioral dysfunctions similar to traits associated with autism spectrum disorders （ASDs）, and these similarities extend to neuroanatomy, neuro...Exposure to mercury can cause immune, sensory, neurological, motor and behavioral dysfunctions similar to traits associated with autism spectrum disorders （ASDs）, and these similarities extend to neuroanatomy, neurotransmitters and biochemistry. It also affects antioxidant system in the cell, resulting in loss of membrane integrity and finally cellular necrosis （Abdel Moneim, 2015）.展开更多
文摘A cross sectional epidemiological study of 93 arc welders in a shipyard was conducted to observe the adverse effect of exposure to manganese welding fumes. Among them, 37 workers with paired controls were given the neurobehavioral tests. Air concentration of manganese in working place, hair manganese and platelet 5 hydroxytryptamine in both exposed workers and controls was also measured. The higher percentage of respiratory symptoms including sour throat and dyspnea in the welders were observed as compared with the controls. The results of neurobehavioral tests showed that the welders exhibited poorer performance in simple reaction time and Santa Ana dexterity tests than that in the controls. The hair manganese concentration was higher and the blood platelet 5 HT level decreased in the welders. In conclusion, symptoms in the welders might be related to the exposure of manganese. Long term exposure to manganese welding fume could cause the change in simple reaction time and Santa Ana dexterity tests. The hair manganese concentration could be used as a biological monitoring index of exposure to manganese.
文摘Exposure to mercury can cause immune, sensory, neurological, motor and behavioral dysfunctions similar to traits associated with autism spectrum disorders （ASDs）, and these similarities extend to neuroanatomy, neurotransmitters and biochemistry. It also affects antioxidant system in the cell, resulting in loss of membrane integrity and finally cellular necrosis （Abdel Moneim, 2015）.
