目的对34例异常血红蛋白Hb New York患者进行基因诊断并分析其血液学特征。方法应用血常规检测和血红蛋白电泳对所有采集的外周血标本进行分析,使用gap-PCR、PCR-RDB和DNA测序方法对所有提取的DNA标本进行β珠蛋白基因的鉴定。结果经基...目的对34例异常血红蛋白Hb New York患者进行基因诊断并分析其血液学特征。方法应用血常规检测和血红蛋白电泳对所有采集的外周血标本进行分析,使用gap-PCR、PCR-RDB和DNA测序方法对所有提取的DNA标本进行β珠蛋白基因的鉴定。结果经基因检测,25例病例为单纯的Hb New York杂合子,其红细胞参数表现为正常或轻度降低,血红蛋白电泳提示43.9%~52.0%的Hb K异常带;1例为Hb New York合并β0-地中海贫血,表现为明显降低的红细胞参数和升高的Hb K(91.8%);8例为Hb New York合并α-地中海贫血,其血液学特征也有不同的改变。结论单纯的Hb New York杂合子无明显的临床表现,但合并其他地中海贫血时可改变其血液学特征。展开更多
目的分析血红蛋白(Hb)New York在不同年龄段的携带人群中的表达差异。方法收集2017-10~2020-03在该院体检、就诊的103351例外周血和脐带血,55909例新生儿末梢血,对筛查结果为Hb New York的样本进行血液学分析和基因型检测。结果携带Hb N...目的分析血红蛋白(Hb)New York在不同年龄段的携带人群中的表达差异。方法收集2017-10~2020-03在该院体检、就诊的103351例外周血和脐带血,55909例新生儿末梢血,对筛查结果为Hb New York的样本进行血液学分析和基因型检测。结果携带Hb New York的样本共185例,其中脐带血4例,新生儿58例,成人123例。胎儿脐带血中Hb New York的含量为(1.30±0.94)%,新生儿含量为(7.87±6.21)%,成人含量为(43.30±2.83)%。携带Hb New York的成人血液学参数均处于正常参考值范围,除红细胞平均血红蛋白浓度(MCHC)外,其他参数与正常成人对照组比较差异均有统计学意义。基因检测显示,Hb New York杂合子167例,Hb New York复合静止型α-地贫7例,Hb New York复合轻型α-地贫11例。结论Hb New York在不同年龄人群的含量不同,与β珠蛋白基因的表达水平正相关。携带者血液学表型正常,合并地贫易表现为贫血,在地贫筛查与婚检、孕检的遗传咨询中值得关注。展开更多
This book presents general theories and applications of structural optimization methods. The first chapter of the book introduces various basic concepts of structural optimization through several illustrative examples...This book presents general theories and applications of structural optimization methods. The first chapter of the book introduces various basic concepts of structural optimization through several illustrative examples. Chapter 2 is devoted to a comprehensive review of math- ematical programming methods, including classical methods such as the simplex method, the （SLP） method, the interior point method and relatively new approaches such as genetic algo- rithms. The third chapter presents the main topic of this book, the SLP methods based on the incremental equations of structures. Some useful techniques in implementation of SLP, including the move limit, scaling and active constraint identifying, are discussed. In chapter 4, classical optimality criterion approaches, including the fully stress approach for truss struc- tures and its extensions for membrane and plate structures, are presented with demonstrative examples. The remaining chapters develop an overview of structural optimization problems, among which are dynamic optimization, multi-criterion optimization, earlier work on the op- timal layouts of plates, as well as some practical issues in general size and shape optimization problems.展开更多
The purpose of this research is to see the image of New York and London in Charles Dickens＇s writings. In American Notes （1987）, on the surface, the city shows Dickens＇s eye of observation, revealing the dark side...The purpose of this research is to see the image of New York and London in Charles Dickens＇s writings. In American Notes （1987）, on the surface, the city shows Dickens＇s eye of observation, revealing the dark side of the city. However, his writing expresses more than what he sees. In this paper, the author sees New York and London not only as realistic accounts of what things look like, but also a true realization of how Dickens feels about himself, and about the country in which he was situated in. In Oliver Twist （2003）, a New York prison can be linked to Dickens＇s London, representing the darkness of the city with the prison cell and its suggestiveness, including punishment, exclusion, and dehumanization. A New York Asylum reveals the dialectic of order and disorder, in a way which alienation brings out the crisis of humanity. This research shows that New York is an extension of London, in a way which the personal crisis is vividly revealed, as the reader can see in Charles Dickens. A Life （2012）. Through New York, Dickens is more conscious about his London childhood, as spatial representations of London have their own symbolic meanings展开更多
Many new cities and new areas in China are planning to build a Central Park.Taking New York Central Park as an example,this study analyzed the design of ecological environment,the people-oriented planning and the sust...Many new cities and new areas in China are planning to build a Central Park.Taking New York Central Park as an example,this study analyzed the design of ecological environment,the people-oriented planning and the sustainable development of it,and summarized the enlightenment to the planning of China’s Central Park.展开更多
America is a nation of immigrants and New York is the destination of many immigrants. In this article, immigrants to New York from three countries are examined. The third wave of immigrants has brought a lot of change...America is a nation of immigrants and New York is the destination of many immigrants. In this article, immigrants to New York from three countries are examined. The third wave of immigrants has brought a lot of changes. The newly arrived immigrants employ different patterns of assimilation while assimilating into American society. This is due to the fact that the problems they face are different from those of old immigrants.展开更多
Based on Robert E.Park’s theoretical frame of social urban study,the“psychophysical mechanism”,urban poetics mainly researches the mutual relations between the physical and the moral organizations of a city in urba...Based on Robert E.Park’s theoretical frame of social urban study,the“psychophysical mechanism”,urban poetics mainly researches the mutual relations between the physical and the moral organizations of a city in urban poems,novels and dramas.This article considers John Updike as an urban poet since his poem collection Americana(2001)is a collection of urban poems.One of the representative poems,the sonnet“New York City”,depicts a despairing“separate nation”by presenting three typical physical cityscapes:television,beggars and skyscrapers.Each physical cityscape reveals its cultural value and social tradition of the city,and the psychological problems of the city dwellers.Tracing Updike’s personal urban experience and the poem’s intertextual space,this article explores his criticism on American big city:the alienated human relations,the anxiety of city life and the smallness of solipsism.His intention to parody John Milton’s Pandemonium in Paradise Lost,and to pay homage to Walt Whitman,reveals that this sonnet embodies rich connotations of urban poetics.展开更多
Saul Bellow’s seventh novel Mr.Sammler’s Planet combines the urban narrative of New York City with the Holocaust narrative,revealing the crisis of postmodern American society.This paper explores Sammler’s unique pe...Saul Bellow’s seventh novel Mr.Sammler’s Planet combines the urban narrative of New York City with the Holocaust narrative,revealing the crisis of postmodern American society.This paper explores Sammler’s unique perspective as a witness to the Holocaust history and the social phenomena of the 1960s,so as to excavate the characteristics of New York City.Under the shackles of modern instrumental rationality and social order,the feverish Holocaust turns into fanatical destruction that subverts traditional ethical values.Sammler discerns the destructive factors in history and the darkness in human nature,but he is not entirely pessimistic and makes exploration for the future of New York City.展开更多
SARS-CoV-2, a novel coronavirus that causes the human disease COVID-19, was determined to be the cause of a cluster of pneumonia cases in Wuhan, China which began in December 2019 [1]. The first case in the United Sta...SARS-CoV-2, a novel coronavirus that causes the human disease COVID-19, was determined to be the cause of a cluster of pneumonia cases in Wuhan, China which began in December 2019 [1]. The first case in the United States reportedly occurred on 20 January 2020 in Washington state in a patient with a history of travel to Wuhan [2]. We report an earlier case of COVID-19 in Queens, New York in November 2019. While it is not perfectly clear from the initial November 2019 emergency department case presentation, if the patient had influenza alone, COVID-19 alone, or combined influenza and COVID-19 infection, presenting lung lesions and constitutional symptoms, later follow-up antibody and immune cell analyses, and the possibility of false-positive RIDT, do strongly suggest initial COVID-19 infection (with or without initial influenza infection). This clinical paper becomes important, because it may describe the earliest now-reported COVID-19 case in the United States, and because emergency department and post-emergency department treatments contributed to a successful patient outcome.展开更多
China Textile & Apparel Trade Show will celebrate the 9~th convention from June 18 to June 20, 2008 at Javits Convention Center of New York city. The trade show, sponsored by China National Textile & Apparel C...China Textile & Apparel Trade Show will celebrate the 9~th convention from June 18 to June 20, 2008 at Javits Convention Center of New York city. The trade show, sponsored by China National Textile & Apparel Council (CNTAC) and co-organized by the Sub-Council of Textile Industry,展开更多
Life changed for companies and people throughout the world after the September 11 terrorist attacks on the World Trade Center. Few felt the impact on its operations as keenly as the Port Authority of New York and New ...Life changed for companies and people throughout the world after the September 11 terrorist attacks on the World Trade Center. Few felt the impact on its operations as keenly as the Port Authority of New York and New Jersey. This unique public agency operates vital transportation and trade facilities at the core of the New展开更多
In the Emigrant Savings Bank building,the chairman’s floor,the classically elegant decoration creates an atmosphere unique to traditional American Businesses.If it were not for the shelves of the Siku Quanshu,the cal...In the Emigrant Savings Bank building,the chairman’s floor,the classically elegant decoration creates an atmosphere unique to traditional American Businesses.If it were not for the shelves of the Siku Quanshu,the calligraphy hanging in the office,and the Chairman’s self-introduction in Chinese,it would be very hard to imagine that this traditional American family business had such deep ties to China.展开更多
New York, USA, on 8 October 2009-The world’s largest economies took the biggest hit in the World Economic Forum’s second annual Financial Development Report released today.
New Jersey Governor James E.McGreevey today joined Port AuthorityChairman Anthony R.Coscia at the Eliza-beth-Port Authority Marine Terminal tohail a record-breaking year for the Port ofNew York and New Jersey as he an...New Jersey Governor James E.McGreevey today joined Port AuthorityChairman Anthony R.Coscia at the Eliza-beth-Port Authority Marine Terminal tohail a record-breaking year for the Port ofNew York and New Jersey as he announcedthe 2003 international trade statistics.Thelargest port on the east coast of NorthAmerica saw its container volumes growby more than eight percent and the value oftotal cargo in the port increased nearly 12percent.展开更多
The 8th China Textile and Apparel Trade Show(New York)sponsored by China Textile and Apparel Council and organized by CCPIT TEX,STS and Youthful USA held from June 12th to 14th in Javits Convention Center in New York ...The 8th China Textile and Apparel Trade Show(New York)sponsored by China Textile and Apparel Council and organized by CCPIT TEX,STS and Youthful USA held from June 12th to 14th in Javits Convention Center in New York and now it is all set to open. China Textile and Apparel Trade Show(New York)has been successfully held in the last seven years through the careful operation of the sponsor and the organizers and the support of the展开更多
Air pollution is considered a risk factor for asthma. In this paper, we analyze the association between daily hospital admissions for asthma and ambient air pollution concentrations in four New York City counties. Neg...Air pollution is considered a risk factor for asthma. In this paper, we analyze the association between daily hospital admissions for asthma and ambient air pollution concentrations in four New York City counties. Negative binomial regression is used to model the association between daily asthma hospital admissions and ambient air pollution concentrations. Potential confounding factors such as heat index, day of week, holidays, yearly population changes, and seasonal and long-term trends are controlled for in the models. Nitrogen dioxide (NO2), sulfur dioxide (SO2) and carbon monoxide (CO) show the most consistent statistically significant associations with daily hospitalizations for asthma during the entire period (1996-2000). The associations are stronger for children (0 - 17 years) than for adults (18 - 64 years). Relative risks (RR) for the inter-quartile range (IQR) of same day 24-hour average pollutant concentration and asthma hospitalizations for children for the four county hospitalization totals were: NO2 (IQR = 0.011 ppm, RR = 1.017, 95% CI = 1.001, 1.034), SO2 (IQR = 0.008 ppm, RR = 1.023, 95% CI = 1.004, 1.042), CO (IQR = 0.232 ppm, RR = 1.014, 95% CI = 1.003, 1.025). In the case of ozone (O3) and particulate matter (PM2.5) statistically significant associations were found for daily one-hour maxima values and children’s asthma hospitalization in models that used lagged values for air pollution concentrations. Five-day weighted average lag models resulted in these estimates: O3 (one-hour maxima) (IQR = 0.025 ppm, RR = 1.049, 95% CI = 1.002, 1.098), PM2.5 (one-hour maxima) (IQR = 16.679 μg/m3, RR = 1.055, 95% CI = 1.008, 1.103). In addition, seasonal variations were also explored for PM2.5 and statistically significant associations with daily hospital admissions for asthma were found during the colder months (November-March) of the year. Important differences in pollution effects were found across pollutants, counties, and age groups. The results for PM2.5 suggest that the composition of PM is important to this health outcome, since the major sources of NYC PM differ between winter and summer months.展开更多
文摘目的对34例异常血红蛋白Hb New York患者进行基因诊断并分析其血液学特征。方法应用血常规检测和血红蛋白电泳对所有采集的外周血标本进行分析,使用gap-PCR、PCR-RDB和DNA测序方法对所有提取的DNA标本进行β珠蛋白基因的鉴定。结果经基因检测,25例病例为单纯的Hb New York杂合子,其红细胞参数表现为正常或轻度降低,血红蛋白电泳提示43.9%~52.0%的Hb K异常带;1例为Hb New York合并β0-地中海贫血,表现为明显降低的红细胞参数和升高的Hb K(91.8%);8例为Hb New York合并α-地中海贫血,其血液学特征也有不同的改变。结论单纯的Hb New York杂合子无明显的临床表现,但合并其他地中海贫血时可改变其血液学特征。
文摘目的分析血红蛋白(Hb)New York在不同年龄段的携带人群中的表达差异。方法收集2017-10~2020-03在该院体检、就诊的103351例外周血和脐带血,55909例新生儿末梢血,对筛查结果为Hb New York的样本进行血液学分析和基因型检测。结果携带Hb New York的样本共185例,其中脐带血4例,新生儿58例,成人123例。胎儿脐带血中Hb New York的含量为(1.30±0.94)%,新生儿含量为(7.87±6.21)%,成人含量为(43.30±2.83)%。携带Hb New York的成人血液学参数均处于正常参考值范围,除红细胞平均血红蛋白浓度(MCHC)外,其他参数与正常成人对照组比较差异均有统计学意义。基因检测显示,Hb New York杂合子167例,Hb New York复合静止型α-地贫7例,Hb New York复合轻型α-地贫11例。结论Hb New York在不同年龄人群的含量不同,与β珠蛋白基因的表达水平正相关。携带者血液学表型正常,合并地贫易表现为贫血,在地贫筛查与婚检、孕检的遗传咨询中值得关注。
文摘This book presents general theories and applications of structural optimization methods. The first chapter of the book introduces various basic concepts of structural optimization through several illustrative examples. Chapter 2 is devoted to a comprehensive review of math- ematical programming methods, including classical methods such as the simplex method, the （SLP） method, the interior point method and relatively new approaches such as genetic algo- rithms. The third chapter presents the main topic of this book, the SLP methods based on the incremental equations of structures. Some useful techniques in implementation of SLP, including the move limit, scaling and active constraint identifying, are discussed. In chapter 4, classical optimality criterion approaches, including the fully stress approach for truss struc- tures and its extensions for membrane and plate structures, are presented with demonstrative examples. The remaining chapters develop an overview of structural optimization problems, among which are dynamic optimization, multi-criterion optimization, earlier work on the op- timal layouts of plates, as well as some practical issues in general size and shape optimization problems.
文摘The purpose of this research is to see the image of New York and London in Charles Dickens＇s writings. In American Notes （1987）, on the surface, the city shows Dickens＇s eye of observation, revealing the dark side of the city. However, his writing expresses more than what he sees. In this paper, the author sees New York and London not only as realistic accounts of what things look like, but also a true realization of how Dickens feels about himself, and about the country in which he was situated in. In Oliver Twist （2003）, a New York prison can be linked to Dickens＇s London, representing the darkness of the city with the prison cell and its suggestiveness, including punishment, exclusion, and dehumanization. A New York Asylum reveals the dialectic of order and disorder, in a way which alienation brings out the crisis of humanity. This research shows that New York is an extension of London, in a way which the personal crisis is vividly revealed, as the reader can see in Charles Dickens. A Life （2012）. Through New York, Dickens is more conscious about his London childhood, as spatial representations of London have their own symbolic meanings
文摘Many new cities and new areas in China are planning to build a Central Park.Taking New York Central Park as an example,this study analyzed the design of ecological environment,the people-oriented planning and the sustainable development of it,and summarized the enlightenment to the planning of China’s Central Park.
文摘America is a nation of immigrants and New York is the destination of many immigrants. In this article, immigrants to New York from three countries are examined. The third wave of immigrants has brought a lot of changes. The newly arrived immigrants employ different patterns of assimilation while assimilating into American society. This is due to the fact that the problems they face are different from those of old immigrants.
基金This paper is one of the research progress and outcomes of the programs“Urban Poetics of John Updike’s Poetry”(2016SJD750045)“Study on Multimodal Narrative in the 21st Century American Novels”(20BWW036),and“Study on Shakespeare’s City Play”(2021SJA1192).
文摘Based on Robert E.Park’s theoretical frame of social urban study,the“psychophysical mechanism”,urban poetics mainly researches the mutual relations between the physical and the moral organizations of a city in urban poems,novels and dramas.This article considers John Updike as an urban poet since his poem collection Americana(2001)is a collection of urban poems.One of the representative poems,the sonnet“New York City”,depicts a despairing“separate nation”by presenting three typical physical cityscapes:television,beggars and skyscrapers.Each physical cityscape reveals its cultural value and social tradition of the city,and the psychological problems of the city dwellers.Tracing Updike’s personal urban experience and the poem’s intertextual space,this article explores his criticism on American big city:the alienated human relations,the anxiety of city life and the smallness of solipsism.His intention to parody John Milton’s Pandemonium in Paradise Lost,and to pay homage to Walt Whitman,reveals that this sonnet embodies rich connotations of urban poetics.
文摘Saul Bellow’s seventh novel Mr.Sammler’s Planet combines the urban narrative of New York City with the Holocaust narrative,revealing the crisis of postmodern American society.This paper explores Sammler’s unique perspective as a witness to the Holocaust history and the social phenomena of the 1960s,so as to excavate the characteristics of New York City.Under the shackles of modern instrumental rationality and social order,the feverish Holocaust turns into fanatical destruction that subverts traditional ethical values.Sammler discerns the destructive factors in history and the darkness in human nature,but he is not entirely pessimistic and makes exploration for the future of New York City.
文摘SARS-CoV-2, a novel coronavirus that causes the human disease COVID-19, was determined to be the cause of a cluster of pneumonia cases in Wuhan, China which began in December 2019 [1]. The first case in the United States reportedly occurred on 20 January 2020 in Washington state in a patient with a history of travel to Wuhan [2]. We report an earlier case of COVID-19 in Queens, New York in November 2019. While it is not perfectly clear from the initial November 2019 emergency department case presentation, if the patient had influenza alone, COVID-19 alone, or combined influenza and COVID-19 infection, presenting lung lesions and constitutional symptoms, later follow-up antibody and immune cell analyses, and the possibility of false-positive RIDT, do strongly suggest initial COVID-19 infection (with or without initial influenza infection). This clinical paper becomes important, because it may describe the earliest now-reported COVID-19 case in the United States, and because emergency department and post-emergency department treatments contributed to a successful patient outcome.
文摘China Textile & Apparel Trade Show will celebrate the 9~th convention from June 18 to June 20, 2008 at Javits Convention Center of New York city. The trade show, sponsored by China National Textile & Apparel Council (CNTAC) and co-organized by the Sub-Council of Textile Industry,
文摘Life changed for companies and people throughout the world after the September 11 terrorist attacks on the World Trade Center. Few felt the impact on its operations as keenly as the Port Authority of New York and New Jersey. This unique public agency operates vital transportation and trade facilities at the core of the New
文摘In the Emigrant Savings Bank building,the chairman’s floor,the classically elegant decoration creates an atmosphere unique to traditional American Businesses.If it were not for the shelves of the Siku Quanshu,the calligraphy hanging in the office,and the Chairman’s self-introduction in Chinese,it would be very hard to imagine that this traditional American family business had such deep ties to China.
文摘New York, USA, on 8 October 2009-The world’s largest economies took the biggest hit in the World Economic Forum’s second annual Financial Development Report released today.
文摘New Jersey Governor James E.McGreevey today joined Port AuthorityChairman Anthony R.Coscia at the Eliza-beth-Port Authority Marine Terminal tohail a record-breaking year for the Port ofNew York and New Jersey as he announcedthe 2003 international trade statistics.Thelargest port on the east coast of NorthAmerica saw its container volumes growby more than eight percent and the value oftotal cargo in the port increased nearly 12percent.
文摘The 8th China Textile and Apparel Trade Show(New York)sponsored by China Textile and Apparel Council and organized by CCPIT TEX,STS and Youthful USA held from June 12th to 14th in Javits Convention Center in New York and now it is all set to open. China Textile and Apparel Trade Show(New York)has been successfully held in the last seven years through the careful operation of the sponsor and the organizers and the support of the
文摘Air pollution is considered a risk factor for asthma. In this paper, we analyze the association between daily hospital admissions for asthma and ambient air pollution concentrations in four New York City counties. Negative binomial regression is used to model the association between daily asthma hospital admissions and ambient air pollution concentrations. Potential confounding factors such as heat index, day of week, holidays, yearly population changes, and seasonal and long-term trends are controlled for in the models. Nitrogen dioxide (NO2), sulfur dioxide (SO2) and carbon monoxide (CO) show the most consistent statistically significant associations with daily hospitalizations for asthma during the entire period (1996-2000). The associations are stronger for children (0 - 17 years) than for adults (18 - 64 years). Relative risks (RR) for the inter-quartile range (IQR) of same day 24-hour average pollutant concentration and asthma hospitalizations for children for the four county hospitalization totals were: NO2 (IQR = 0.011 ppm, RR = 1.017, 95% CI = 1.001, 1.034), SO2 (IQR = 0.008 ppm, RR = 1.023, 95% CI = 1.004, 1.042), CO (IQR = 0.232 ppm, RR = 1.014, 95% CI = 1.003, 1.025). In the case of ozone (O3) and particulate matter (PM2.5) statistically significant associations were found for daily one-hour maxima values and children’s asthma hospitalization in models that used lagged values for air pollution concentrations. Five-day weighted average lag models resulted in these estimates: O3 (one-hour maxima) (IQR = 0.025 ppm, RR = 1.049, 95% CI = 1.002, 1.098), PM2.5 (one-hour maxima) (IQR = 16.679 μg/m3, RR = 1.055, 95% CI = 1.008, 1.103). In addition, seasonal variations were also explored for PM2.5 and statistically significant associations with daily hospital admissions for asthma were found during the colder months (November-March) of the year. Important differences in pollution effects were found across pollutants, counties, and age groups. The results for PM2.5 suggest that the composition of PM is important to this health outcome, since the major sources of NYC PM differ between winter and summer months.
