目的:观察新三期中药外治方案治疗急性外踝韧带损伤的临床疗效。方法:将2023年7月至2023年12月期间招募的64例急性外踝韧带损伤患者,按照治疗方法不同分为观察组和对照组,每组32例。观察组男17例,女15例;年龄25~36(30.59±3.10)岁;...目的:观察新三期中药外治方案治疗急性外踝韧带损伤的临床疗效。方法:将2023年7月至2023年12月期间招募的64例急性外踝韧带损伤患者,按照治疗方法不同分为观察组和对照组,每组32例。观察组男17例,女15例;年龄25~36(30.59±3.10)岁;采用新三期中药外治方案联合“POLICE”治疗方案即保护(protect)、适当负重(optimal loading)、冰敷(ice)、加压包扎(compression)和抬高患肢(elevation)。对照组男14例,女18例;年龄24~37(30.03±3.19)岁;采用“POLICE”治疗方案。分别在初次入组和治疗第1、6周后采用视觉模拟评分(visual analogue scale,VAS)评估和Figure of 8测量法评估受试者踝关节疼痛和肿胀程度。同时采用美国足踝外科踝功能评分(American Orthopaedic Foot and Ankle Society,AOFAS)和Karlsson踝关节功能评分系统评价各阶段患者踝关节功能改善情况。通过MRI特定图像观察距腓前韧带生物愈合程度,通过计算信噪比(signal to noise ratio,SNR)评估,信噪比越低代表韧带含水量越低,愈合越好。结果:所有患者获得6周随访。治疗前两组VAS、AOFAS和Karlsson评分差异无统计学意义(P>0.05),治疗1周和6周后,两组VAS、AOFAS评分和Karlsson评分均较治疗前显著改善(P<0.05)。治疗1周后,观察组VAS(3.21±0.87)分,低于对照组(4.21±1.50)分(P<0.05)。治疗1周后,观察组AOFAS和Karlsson评分[(50.84±4.70)分,(49.97±4.00)分],高于对照组[(46.91±5.56)分,(46.66±5.36)分],P<0.05。MRI图像显示,治疗6周后,观察组SNR值75.25±16.59,低于对照组的85.81±15.55(P<0.05)。结论:与对照组相比,新三期中药外治方案早期临床疗效显著,能够明显减轻急性外踝韧带损伤患者踝关节的疼痛和肿胀程度,提高韧带修复质量,促进患者踝关节功能的恢复。展开更多
Syndrome differentiation is a methodology unique to Chinese medicine. It threads the diagnosis process with clinical treatment into a holistic web of links to determine and regulate the patterns of dysfunctions in t...Syndrome differentiation is a methodology unique to Chinese medicine. It threads the diagnosis process with clinical treatment into a holistic web of links to determine and regulate the patterns of dysfunctions in the human body. It is seen as the essence of Chinese medicine because it takes into account the theoretical principles, diagnostic methodologies and the modality of treatment holistically. In this process the progressive development and changes of syndromes are also considered by the physician. This paper is a systematic study of the methodology of syndrome differentiation in relation to its clinical applications in the treatment of diseases. To illustrate the efficacy of syndrome differentiation, the relationship between pattern identification and diseases is analysed to provide a guiding principle for integration between Chinese medicine and Western medicine. nclude cancer, cardiovascular and metabolic syndromes. A study of renal and hepatic Diseases being selected include cancer, cardiovascular and metabolic syndromes. A study of renal and hepatic diseases related to lifestyle is also included to highlight the clinical efficacy of syndrome differentiation. The paper also includes an analytical summary of the theoretical advancements made in integrative differentiation methodology during the past five decades which links to the recent clinical thinking and practice.展开更多
文摘目的:观察新三期中药外治方案治疗急性外踝韧带损伤的临床疗效。方法:将2023年7月至2023年12月期间招募的64例急性外踝韧带损伤患者,按照治疗方法不同分为观察组和对照组,每组32例。观察组男17例,女15例;年龄25~36(30.59±3.10)岁;采用新三期中药外治方案联合“POLICE”治疗方案即保护(protect)、适当负重(optimal loading)、冰敷(ice)、加压包扎(compression)和抬高患肢(elevation)。对照组男14例,女18例;年龄24~37(30.03±3.19)岁;采用“POLICE”治疗方案。分别在初次入组和治疗第1、6周后采用视觉模拟评分(visual analogue scale,VAS)评估和Figure of 8测量法评估受试者踝关节疼痛和肿胀程度。同时采用美国足踝外科踝功能评分(American Orthopaedic Foot and Ankle Society,AOFAS)和Karlsson踝关节功能评分系统评价各阶段患者踝关节功能改善情况。通过MRI特定图像观察距腓前韧带生物愈合程度,通过计算信噪比(signal to noise ratio,SNR)评估,信噪比越低代表韧带含水量越低,愈合越好。结果:所有患者获得6周随访。治疗前两组VAS、AOFAS和Karlsson评分差异无统计学意义(P>0.05),治疗1周和6周后,两组VAS、AOFAS评分和Karlsson评分均较治疗前显著改善(P<0.05)。治疗1周后,观察组VAS(3.21±0.87)分,低于对照组(4.21±1.50)分(P<0.05)。治疗1周后,观察组AOFAS和Karlsson评分[(50.84±4.70)分,(49.97±4.00)分],高于对照组[(46.91±5.56)分,(46.66±5.36)分],P<0.05。MRI图像显示,治疗6周后,观察组SNR值75.25±16.59,低于对照组的85.81±15.55(P<0.05)。结论:与对照组相比,新三期中药外治方案早期临床疗效显著,能够明显减轻急性外踝韧带损伤患者踝关节的疼痛和肿胀程度,提高韧带修复质量,促进患者踝关节功能的恢复。
文摘Syndrome differentiation is a methodology unique to Chinese medicine. It threads the diagnosis process with clinical treatment into a holistic web of links to determine and regulate the patterns of dysfunctions in the human body. It is seen as the essence of Chinese medicine because it takes into account the theoretical principles, diagnostic methodologies and the modality of treatment holistically. In this process the progressive development and changes of syndromes are also considered by the physician. This paper is a systematic study of the methodology of syndrome differentiation in relation to its clinical applications in the treatment of diseases. To illustrate the efficacy of syndrome differentiation, the relationship between pattern identification and diseases is analysed to provide a guiding principle for integration between Chinese medicine and Western medicine. nclude cancer, cardiovascular and metabolic syndromes. A study of renal and hepatic Diseases being selected include cancer, cardiovascular and metabolic syndromes. A study of renal and hepatic diseases related to lifestyle is also included to highlight the clinical efficacy of syndrome differentiation. The paper also includes an analytical summary of the theoretical advancements made in integrative differentiation methodology during the past five decades which links to the recent clinical thinking and practice.
