AIM:To investigate auto-cortex of crystalline lens induced iris neovascularization (INV). METHODS: Thirty-six eyes of 36 guinea-pigs were included and divided into three groups randomly in this cohort study. Group A: ...AIM:To investigate auto-cortex of crystalline lens induced iris neovascularization (INV). METHODS: Thirty-six eyes of 36 guinea-pigs were included and divided into three groups randomly in this cohort study. Group A: the right lens nucleus was extracted and the remaining cortical lens material was aspirated thoroughly.. Group B: the lens was removed and 30 mu L precipitated lens cortex was injected into the anterior chamber again. Group C: aspirated the lens cortex of the left eyes and inject them into the right anterior chambers about 10 mu L. Clinical changes were followed by slit-lamp examination and photograph. The eye balls were enucleated at the day of 2, 4, 7, 11, 13, 17 after operation. HE was used to detect the pathological changes. ' RESULTS:Group A:INV had not been observed until the end of empirical study. The stromal layer contained thick wall vessels, without expansion. Group B: All eyes developed INV. Postoperative (po) 7 days; the eyes developed intense and extensive INV. The vessels of iris expanded remarkably and neovascularization was observed erupting from it's lateral wall and stretching towards the anterior surface. Poll days, INV regressed gradually after lens cortex had been absorbed. Group C: Po four (4) days, new blood vessels liking red line were presented on the anterior surface of the iris and they were not obvious. CONCLUSION: Anterior chamber inside lens coriaceous can induce iris new blood vessels.展开更多
In a first-of-its-kind finding,a new stroke-healing gel helped regrow neurons and blood vessels in mice with stroke-damaged brains.The results suggest that such an approach may someday be a new therapy for stroke in p...In a first-of-its-kind finding,a new stroke-healing gel helped regrow neurons and blood vessels in mice with stroke-damaged brains.The results suggest that such an approach may someday be a new therapy for stroke in people.The study tested this in laboratory mice to determine if it would repair the brain in a model展开更多
基金Supported by National Natural Science Foundation of China (No.39870801)Innovative Drug and Technological Development Program of Guangzhou Municipality, China (No.2006Z3-E4091)Guangdong Provincial Medical Science and Technology Research Foundation, China(No.B2006118)
文摘AIM:To investigate auto-cortex of crystalline lens induced iris neovascularization (INV). METHODS: Thirty-six eyes of 36 guinea-pigs were included and divided into three groups randomly in this cohort study. Group A: the right lens nucleus was extracted and the remaining cortical lens material was aspirated thoroughly.. Group B: the lens was removed and 30 mu L precipitated lens cortex was injected into the anterior chamber again. Group C: aspirated the lens cortex of the left eyes and inject them into the right anterior chambers about 10 mu L. Clinical changes were followed by slit-lamp examination and photograph. The eye balls were enucleated at the day of 2, 4, 7, 11, 13, 17 after operation. HE was used to detect the pathological changes. ' RESULTS:Group A:INV had not been observed until the end of empirical study. The stromal layer contained thick wall vessels, without expansion. Group B: All eyes developed INV. Postoperative (po) 7 days; the eyes developed intense and extensive INV. The vessels of iris expanded remarkably and neovascularization was observed erupting from it's lateral wall and stretching towards the anterior surface. Poll days, INV regressed gradually after lens cortex had been absorbed. Group C: Po four (4) days, new blood vessels liking red line were presented on the anterior surface of the iris and they were not obvious. CONCLUSION: Anterior chamber inside lens coriaceous can induce iris new blood vessels.
文摘In a first-of-its-kind finding,a new stroke-healing gel helped regrow neurons and blood vessels in mice with stroke-damaged brains.The results suggest that such an approach may someday be a new therapy for stroke in people.The study tested this in laboratory mice to determine if it would repair the brain in a model